Primary AppointmentAssociate Professor,
- BS, Biology, Tunghai University
- MS, Biology, University of Wisconsin-Milwaukee
- PhD, Neurobiology, University of Pittsburgh
- PhD, Physiology/Pharmacology, Oregon Health Sciences University
Neuroendocrine regulation of energy balance and stress, regulation of pancreatic islet hormone secretion and glucose homeostasis
At the molecular level, we are investigating signaling mechanisms and molecular targets in cells mediating the effects of CRF peptides. Currently we have been focusing on vesicular nucleotide transporter (VNUT) as a downstream molecular mediator underlying the effects of stress peptides. Our study has suggested that VNUT plays an essential role in maintaining cellular energy homeostasis. We employ multiple approaches including gene targeting, viral gene delivery, RNA interference and primary tissue culture to determine the functional role of VNUT in regulating energy balance in cells. These studies will contribute to understanding the underlying mechanisms of stress on energy balance and have implications in the management of eating disorders, obesity and diabetes.
We are always looking for talented, highly motivated and productive undergraduate students, potential graduate students, and postdoctoral fellows. Please email CV and inquires about currently available positions.