Jeffrey W. Holmes
Primary AppointmentProfessor, Biomedical Engineering
Healing after myocardial infarction, cardiac growth and remodeling, and image-based modeling and diagnosis.
Currently, most of our projects are related to myocardial infarction (MI):
1. a translational effort to help prevent MI by developing new quantitative measures of heart wall motion that improve screening for coronary artery disease;
2. a basic biomechanics project focused on understanding how the structure of a healing infarct gives rise to its mechanical properties and how those mechanical properties influence overall heart function; and
3. longer-term efforts to determine how mechanical factors regulate both cardiac wound healing and remodeling of non-infarcted myocardium in post-MI patients