Ronald P. Taylor
Primary AppointmentProfessor, Biochemistry and Molecular Genetics
- BS, Chemistry, City College of New York, New York, NY
- PhD, Physical Chemistry, Princeton University, Princeton, NJ
- Postdoc, Physical Chemistry, University of Minnesota, Mpls., MN
Clearance of Pathogens: The role of complement in Immunotherapy: New approaches to vaccine generation
We are also developing general approaches for the treatment of cancer based on the interaction of cancer cells with the complement sysstem. In the presence of serum and normal human IgM and/or specific monoclonal antibodies, large amounts of the complement activation product, C3bi, covalently bind to the cancer cells. We are using monoclonal antibodies specific for cell-associated C3bi to facilitate tumor cell targeting and killing.