{"id":9,"date":"2014-09-08T19:30:52","date_gmt":"2014-09-08T19:30:52","guid":{"rendered":"https:\/\/mic.med.virginia.edukashatus-demo\/?page_id=9"},"modified":"2026-02-02T15:47:07","modified_gmt":"2026-02-02T15:47:07","slug":"publications","status":"publish","type":"page","link":"https:\/\/med.virginia.edu\/agaisse\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>Alvarez DE, Agaisse H, The Metalloprotease Mpl Supports Listeria monocytogenes Dissemination through Resolution of Membrane Protrusions into Vacuoles., 2016; Infection and immunity. 84(6) 1806-14.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27068088\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 27068088<\/a><\/p>\n<p>Agaisse H, Molecular and Cellular Mechanisms of Shigella flexneri Dissemination., 2016; Frontiers in cellular and infection microbiology. 6() 29.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27014639\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 27014639<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4786538\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC4786538<\/a><\/p>\n<p>Borinskaya S, Velle KB, Campellone KG, Talman A, Alvarez D, Agaisse H, Wu YI, Loew LM, Mayer BJ, Integration of linear and dendritic actin nucleation in Nck-induced actin comets., 2015; Molecular biology of the cell. 27(2) 247-59.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26609071\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 26609071<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4713129\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC4713129<\/a><\/p>\n<p>Agaisse H, Shigella flexneri serotype 3a: the rise of a superbug., 2015; The Lancet. Infectious diseases. 15(8) 867-8.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25936610\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 25936610<\/a><\/p>\n<p>Kuehl CJ, Dragoi AM, Talman A, Agaisse H, Bacterial spread from cell to cell: beyond actin-based motility., 2015; Trends in microbiology. 23(9) 558-66.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26021574\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 26021574<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4560970\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC4560970<\/a><\/p>\n<p>Dragoi AM, Agaisse H, The Class II Phosphatidylinositol 3-Phosphate Kinase PIK3C2A Promotes Shigella flexneri Dissemination through Formation of Vacuole-Like Protrusions., 2015; Infection and immunity. 83(4) 1695-704.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25667265\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 25667265<\/a><\/p>\n<p>Dragoi AM, Agaisse H, The serine\/threonine kinase STK11 promotes Shigella flexneri dissemination through establishment of cell-cell contacts competent for tyrosine kinase signaling., 2014; Infection and immunity. 82(11) 4447-57.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25114112\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 25114112<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4249316\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC4249316<\/a><\/p>\n<p>Kuehl CJ, Dragoi AM, Agaisse H, The Shigella flexneri type 3 secretion system is required for tyrosine kinase-dependent protrusion resolution, and vacuole escape during bacterial dissemination., 2014; PloS one. 9(11) e112738.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25405985\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 25405985<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4236203\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC4236203<\/a><\/p>\n<p>Dragoi AM, Swiss R, Gao B, Agaisse H, Novel strategies to enforce an epithelial phenotype in mesenchymal cells., 2014; Cancer research. 74(14) 3659-72.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24845104\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 24845104<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4102654\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC4102654<\/a><\/p>\n<p>Alvarez DE, Agaisse H, The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility., 2013; The Journal of cell biology. 202(7) 1075-90.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24062339\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 24062339<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3787377\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC3787377<\/a><\/p>\n<p>Talman AM, Chong R, Chia J, Svitkina T, Agaisse H, Actin network disassembly powers dissemination of Listeria monocytogenes., 2013; Journal of cell science. 127(0) 240-9.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24155331\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 24155331<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3874788\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC3874788<\/a><\/p>\n<p>McDonough JA, Newton HJ, Klum S, Swiss R, Agaisse H, Roy CR, Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening., 2013; mBio. 4(1) e00606-12.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23362322\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 23362322<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3560531\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC3560531<\/a><\/p>\n<p>Alvarez DE, Agaisse H, Casein kinase 2 regulates vaccinia virus actin tail formation., 2012; Virology. 423(2) 143-51.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22209233\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 22209233<\/a><\/p>\n<p>Dragoi AM, Talman AM, Agaisse H, Bruton&#8217;s tyrosine kinase regulates Shigella flexneri dissemination in HT-29 intestinal cells., 2012; Infection and immunity. 81(2) 598-607.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23230296\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 23230296<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3553807\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC3553807<\/a><\/p>\n<p>Chong R, Squires R, Swiss R, Agaisse H, RNAi screen reveals host cell kinases specifically involved in Listeria monocytogenes spread from cell to cell., 2011; PloS one. 6(8) e23399.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21853127\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 21853127<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3154492\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC3154492<\/a><\/p>\n<p>Chong R, Swiss R, Briones G, Stone KL, Gulcicek EE, Agaisse H, Regulatory mimicry in Listeria monocytogenes actin-based motility., 2009; Cell host &amp; microbe. 6(3) 268-78.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19748468\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 19748468<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2752869\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC2752869<\/a><\/p>\n<p>Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E, RNA interference screen for human genes associated with West Nile virus infection., 2008; Nature. 455(7210) 242-5.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18690214\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 18690214<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3136529\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC3136529<\/a><\/p>\n<p>Derr\u00e9 I, Pypaert M, Dautry-Varsat A, Agaisse H, RNAi screen in Drosophila cells reveals the involvement of the Tom complex in Chlamydia infection., 2007; PLoS pathogens. 3(10) 1446-58.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17967059\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 17967059<\/a>\u00a0|\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2042019\" target=\"_blank\" rel=\"noopener noreferrer\">PMCID: PMC2042019<\/a><\/p>\n<p>Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE, Genome-wide RNAi screen for host factors required for intracellular bacterial infection., 2005; Science (New York, N.Y.). 309(5738) 1248-51.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16020693\" target=\"_blank\" rel=\"noopener noreferrer\">PMID: 16020693<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alvarez DE, Agaisse H, The Metalloprotease Mpl Supports Listeria monocytogenes Dissemination through Resolution of Membrane Protrusions into Vacuoles., 2016; Infection and immunity. 84(6) 1806-14.\u00a0PMID: 27068088 Agaisse H, Molecular and Cellular Mechanisms of Shigella flexneri Dissemination., 2016; Frontiers in cellular and infection microbiology. 6() 29.\u00a0PMID: 27014639\u00a0|\u00a0PMCID: PMC4786538 Borinskaya S, Velle KB, Campellone KG, Talman A, Alvarez [&hellip;]<\/p>\n","protected":false},"author":1777,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"open","ping_status":"open","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-9","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Publications - Agaisse Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/agaisse\/publications\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publications - Agaisse Lab\" \/>\n<meta property=\"og:description\" content=\"Alvarez DE, Agaisse H, The Metalloprotease Mpl Supports Listeria monocytogenes Dissemination through Resolution of Membrane Protrusions into Vacuoles., 2016; Infection and immunity. 84(6) 1806-14.\u00a0PMID: 27068088 Agaisse H, Molecular and Cellular Mechanisms of Shigella flexneri Dissemination., 2016; Frontiers in cellular and infection microbiology. 6() 29.\u00a0PMID: 27014639\u00a0|\u00a0PMCID: PMC4786538 Borinskaya S, Velle KB, Campellone KG, Talman A, Alvarez [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/med.virginia.edu\/agaisse\/publications\/\" \/>\n<meta property=\"og:site_name\" content=\"Agaisse Lab\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-02T15:47:07+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/publications\\\/\",\"url\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/publications\\\/\",\"name\":\"Publications - Agaisse Lab\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/#website\"},\"datePublished\":\"2014-09-08T19:30:52+00:00\",\"dateModified\":\"2026-02-02T15:47:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/publications\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/publications\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/publications\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/#website\",\"url\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/\",\"name\":\"Agaisse Lab\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/med.virginia.edu\\\/agaisse\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Publications - Agaisse Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/med.virginia.edu\/agaisse\/publications\/","og_locale":"en_US","og_type":"article","og_title":"Publications - Agaisse Lab","og_description":"Alvarez DE, Agaisse H, The Metalloprotease Mpl Supports Listeria monocytogenes Dissemination through Resolution of Membrane Protrusions into Vacuoles., 2016; Infection and immunity. 84(6) 1806-14.\u00a0PMID: 27068088 Agaisse H, Molecular and Cellular Mechanisms of Shigella flexneri Dissemination., 2016; Frontiers in cellular and infection microbiology. 6() 29.\u00a0PMID: 27014639\u00a0|\u00a0PMCID: PMC4786538 Borinskaya S, Velle KB, Campellone KG, Talman A, Alvarez [&hellip;]","og_url":"https:\/\/med.virginia.edu\/agaisse\/publications\/","og_site_name":"Agaisse Lab","article_modified_time":"2026-02-02T15:47:07+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"8 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/med.virginia.edu\/agaisse\/publications\/","url":"https:\/\/med.virginia.edu\/agaisse\/publications\/","name":"Publications - Agaisse Lab","isPartOf":{"@id":"https:\/\/med.virginia.edu\/agaisse\/#website"},"datePublished":"2014-09-08T19:30:52+00:00","dateModified":"2026-02-02T15:47:07+00:00","breadcrumb":{"@id":"https:\/\/med.virginia.edu\/agaisse\/publications\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/med.virginia.edu\/agaisse\/publications\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/med.virginia.edu\/agaisse\/publications\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/med.virginia.edu\/agaisse\/"},{"@type":"ListItem","position":2,"name":"Publications"}]},{"@type":"WebSite","@id":"https:\/\/med.virginia.edu\/agaisse\/#website","url":"https:\/\/med.virginia.edu\/agaisse\/","name":"Agaisse Lab","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/med.virginia.edu\/agaisse\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/users\/1777"}],"replies":[{"embeddable":true,"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":1,"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":453,"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/pages\/9\/revisions\/453"}],"wp:attachment":[{"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/media?parent=9"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/med.virginia.edu\/agaisse\/wp-json\/wp\/v2\/tags?post=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}