|Office Location: Pinn 4017
Email: wxy9cb at virginia.edu
|Understanding the molecular mechanism during diseases is essential for developing drugs and treatments. By using genetically encoded indicators, we can visualize molecular pathways inside cells or even animals. I am interested in using genetically encoded indicators as tools to investigate the molecular mechanisms during neurodegenerative disorders, like Alzheimer’s disease.|
Postdoctoral Research Associate 11/2020-present
Previous Education and Professional Experiences:
Ph.D. in Biological Sciences 09/2014-07/2020
B.S. Biological Sciences 09/2010-07/2014
Li X†, Zhang Y†, Ai HW. Ratiometric Imaging of Mitochondrial Hydrogen Peroxide in Aβ42-Mediated Neurotoxicity. ACS Sens. 2022 Mar 25;7(3):722-729. †Co-first authors.
Tian X, Zhang Y, Li X, Xiong Y, Wu T, Ai HW. A luciferase prosubstrate and a red bioluminescent calcium indicator for imaging neuronal activity in mice. Nat Commun. 2022 Jul 8;13(1):3967.
Ying Xiong, Yiyu Zhang, Zefan Li, Md Shamim Reza, Xinyu Li, Xiaodong Tian, and Hui-wang Ai. Journal of the American Chemical Society 2022 144 (31), 14101-14111.