Trinh, Bon Q
Primary Appointment
Tenure-track Assistant Professor, Pathology
Education
- PhD, Biomedical Sciences, University of Texas Graduate School of Biomedical Sciences
Contact Information
415 Lane Rd. P.O. Box. 800904
MR5 Building, Rm. 3330
Charlottesville, VA 22908-0904
Telephone: 434-982-2341
Email: bontrinh@virginia.edu
Website: https://tinyurl.com/trinhlaboratory
Research Disciplines
Biochemistry, Bioinformatics and Genomics, Cancer Biology, Cell and Developmental Biology, Computational Biology, Development, Epigenetics, Experimental Pathology, Genetics, Molecular Biology, Molecular Pharmacology, Translational Science
Research Interests
Understanding Protein and RNA regulations of gene expression via chromatin structure in myeloid cell development and diseases
Research Description
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we employ experimental and computational approaches to understand how proteins and RNAs act at chromatin level to control activities of key genes involved in normal myeloid cell maturation, leukemia development, myeloid cell - cancer cell communication in the tumor microenvironment, as well as drug response. The aims are to identify actionable molecular targets and diagnostic biomarkers, and to develop innovative therapeutic strategies for diseases such as cancer.