{"id":2616,"date":"2020-06-29T11:53:33","date_gmt":"2020-06-29T15:53:33","guid":{"rendered":"https:\/\/med.virginia.edu\/bims\/?p=2616"},"modified":"2020-06-29T11:53:33","modified_gmt":"2020-06-29T15:53:33","slug":"qa-infectious-diseases-expert-talks-vaccines-and-covid-19","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/bims\/qa-infectious-diseases-expert-talks-vaccines-and-covid-19\/","title":{"rendered":"Q&amp;A: Infectious Diseases Expert Talks Vaccines and COVID-19"},"content":{"rendered":"<p class=\"processed\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-2617\" src=\"https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/06\/steven_zeichner_covid_19_vaccines_ss_header.jpg\" alt=\"Steven Zeichner\" width=\"250\" height=\"250\" srcset=\"https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/06\/steven_zeichner_covid_19_vaccines_ss_header.jpg 250w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/06\/steven_zeichner_covid_19_vaccines_ss_header-150x150.jpg 150w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/06\/steven_zeichner_covid_19_vaccines_ss_header-200x200.jpg 200w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/06\/steven_zeichner_covid_19_vaccines_ss_header-100x100.jpg 100w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/06\/steven_zeichner_covid_19_vaccines_ss_header-70x70.jpg 70w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/>As the COVID-19 pandemic continues its spread, harming and hampering lives and economies, one thing is clear: we need a vaccine.<\/p>\n<p>Dr. Steven Zeichner, a University of Virginia infectious diseases specialist and researcher, is responding to that challenge. He is using existing technologies and techniques to develop a unique vaccine-making method that he hopes will not only rapidly produce a safe and effective vaccine, but one that is low-cost and highly manufacturable.<\/p>\n<p>Here, he discusses vaccines generally, and his particular approach to vaccine development.<\/p>\n<p><strong>Q. When do you think an approved COVID-19 vaccine will become available?<\/strong><\/p>\n<p>A. That\u2019s still an open question. A year or so from now would be wonderful, but that would be very fast for a new vaccine because there are a lot of things that can go wrong in development. I would be delighted to see it happen.<\/p>\n<p>It would need to first be widely tested in Phase III clinical trials, and then, if proven safe and effective, would have to be approved by the Food and Drug Administration. It then would have to be produced in sufficient quantities to elicit immunity in a significant fraction of the population.<\/p>\n<p><strong>Q. What are the steps involved in creating a vaccine?<\/strong><\/p>\n<p>A. First, we need a vaccine that can elicit an appropriate immune response in an animal.<\/p>\n<p>If that works, then we do a Phase I study in a small number of people to see if they, too, demonstrate immunity with no evidence of a safety problem.<\/p>\n<p>Then a Phase II study is conducted on a larger number of people to see if there\u2019s more evidence of safety and efficacy.<\/p>\n<p>Next, a large Phase III study is needed, where you immunize many, many people and see if the vaccine actually protects them from getting the infection. If so, that would lead to drug approval and production for the general population.<\/p>\n<p>It\u2019s a long process.<\/p>\n<p>In a pandemic situation, there are groups trying to accelerate this by combining phases, which is a reasonable way to go when faced with a crisis. But until we get the Phase III data, we don\u2019t actually know whether the vaccine is going to be safe and protective, with no adverse effects.<\/p>\n<p>Read the full story at <a href=\"https:\/\/news.virginia.edu\/content\/qa-infectious-diseases-expert-talks-vaccines-and-covid-19\" target=\"_blank\" rel=\"noopener noreferrer\">UVA Today, 6\/23\/20<\/a>. Story by Fariss Samarrai. Photo by Sanjay Suchak.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As the COVID-19 pandemic continues its spread, harming and hampering lives and economies, one thing is clear: we need a vaccine. Dr. Steven Zeichner, a University of Virginia infectious diseases specialist and researcher, is responding to that challenge. He is using existing technologies and techniques to develop a unique vaccine-making method that he hopes will [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2617,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[4],"tags":[],"class_list":["post-2616","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-highlights"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Q&amp;A: Infectious Diseases Expert Talks Vaccines and COVID-19 - Biomedical Sciences Graduate Program<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/bims\/qa-infectious-diseases-expert-talks-vaccines-and-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Q&amp;A: Infectious Diseases Expert Talks Vaccines and COVID-19 - Biomedical Sciences Graduate Program\" \/>\n<meta property=\"og:description\" content=\"As the COVID-19 pandemic continues its spread, harming and hampering lives and economies, one thing is clear: we need a vaccine. 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