{"id":2661,"date":"2020-07-20T12:50:18","date_gmt":"2020-07-20T16:50:18","guid":{"rendered":"https:\/\/med.virginia.edu\/bims\/?p=2661"},"modified":"2020-07-20T12:50:18","modified_gmt":"2020-07-20T16:50:18","slug":"brain-cancer-scientists-identify-gene-responsible-for-deadly-glioblastoma","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/bims\/brain-cancer-scientists-identify-gene-responsible-for-deadly-glioblastoma\/","title":{"rendered":"Brain Cancer: Scientists Identify Gene Responsible For Deadly Glioblastoma"},"content":{"rendered":"<p class=\"processed\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-2663\" src=\"https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/07\/hu_li_inline_right.jpg\" alt=\"\" width=\"250\" height=\"250\" srcset=\"https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/07\/hu_li_inline_right.jpg 250w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/07\/hu_li_inline_right-150x150.jpg 150w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/07\/hu_li_inline_right-200x200.jpg 200w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/07\/hu_li_inline_right-100x100.jpg 100w, https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2020\/07\/hu_li_inline_right-70x70.jpg 70w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/>University of Virginia scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal.<\/p>\n<p>The researchers say the oncogene is essential to the survival of the cancer cells. Without it, the cancer cells die. Scientists have already developed many targeted therapies for other cancers with a similar \u201concogene addiction.\u201d<\/p>\n<p>\u201cGlioblastoma is one of the most deadly cancers. Unfortunately, there is no effective treatment option for the disease,\u201d said researcher Hui Li of the\u00a0<a href=\"https:\/\/u7061146.ct.sendgrid.net\/ls\/click?upn=mpkt3et7aBhE1y7FXZskzroyeVATyhLNGR9aTto8A-2Bs-3D_eSy_mUxVefcfwmSeZVijaYaqQXqNgreGSD9GWDVwC97BL0lhZ-2Bw0f9-2F0gJpdy05l1Lp05cGoVz1w4Db6uLsXim6PYwkr3r20Oqt6YRr7-2BbjynJIRisu-2FfO6bYQt9ND7ZnDkSSvmIwgcNX5GqVIEujupHnF-2FPMtDnrUK-2FHZIXzZM8VaI6PMQQtHXVdWMofoU-2B6aDkNyLD4OdmVc9PTDZpeGUIzKlhD-2FJ13DkZ-2FT-2ByZYKyFerKGVQY6ogAjSt7zGoRwJSv6Jdlfpl86xI3bUXlPHke4zZ3CcwLiNFT9VDrHGw251HodNsKLbR-2Blhevo-2BWVNGg1vqNmzBwC2kWfC6mGKj-2Bhh5Kw5zCtFEA35bEqoRxLDBU-3D\">UVA School of Medicine<\/a>\u00a0and the\u00a0<a href=\"https:\/\/cancer.uvahealth.com\/\">UVA Cancer Center<\/a>. \u201cThe current standard option,\u00a0radiation plus temozolomide, which displayed a 2.5-month-better survival rate, was hailed as a great success. Clearly, better understanding and new therapeutic targets are urgently needed.<\/p>\n<p>\u201cThe novel oncogene we discovered promises to be an Achilles\u2019 heel of glioblastoma, with its specific targeting potentially an effective approach for the treatment of the disease.\u201d<\/p>\n<p>Read the full story by Josh Barney at <a href=\"https:\/\/news.virginia.edu\/content\/brain-cancer-scientists-identify-gene-responsible-deadly-glioblastoma\" target=\"_blank\" rel=\"noopener noreferrer\">UVA Today, 7\/14\/20<\/a> (Contributed photo).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>University of Virginia scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal. The researchers say the oncogene is essential to the survival of the cancer cells. Without it, the cancer cells die. Scientists have [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2663,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[4],"tags":[],"class_list":["post-2661","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-highlights"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Brain Cancer: Scientists Identify Gene Responsible For Deadly Glioblastoma - Biomedical Sciences Graduate Program<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/bims\/brain-cancer-scientists-identify-gene-responsible-for-deadly-glioblastoma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brain Cancer: Scientists Identify Gene Responsible For Deadly Glioblastoma - Biomedical Sciences Graduate Program\" \/>\n<meta property=\"og:description\" content=\"University of Virginia scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. 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