{"id":998,"date":"2019-07-11T12:54:53","date_gmt":"2019-07-11T16:54:53","guid":{"rendered":"https:\/\/med.virginia.edu\/bims\/?p=998"},"modified":"2019-08-14T09:02:28","modified_gmt":"2019-08-14T13:02:28","slug":"rheumatoid-arthritis-discovery","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/bims\/rheumatoid-arthritis-discovery\/","title":{"rendered":"Surprise Rheumatoid Arthritis Discovery Points to New Treatment for Joint Inflammation"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-539\" src=\"https:\/\/med.virginia.edu\/bims\/wp-content\/uploads\/sites\/390\/2019\/07\/Ravichandran-Arandjelovic_smsq.jpg\" alt=\"Kodi Ravichandran and Sanja Arandjelovic\" width=\"300\" height=\"240\" \/>Kodi Ravichandran, left, and Sanja Arandjelovic led new research into the causes of rheumatoid arthritis flare-ups.<\/p>\n<p>Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease.\u00a0 The new findings about rheumatoid arthritis came in an unexpected fashion. Sanja Arandjelovic, a research scientist in the Ravichandran group, was seeking to better understand what causes the inflammation associated with inflammatory arthritis when she noted that deleting a gene called ELMO1 alleviated arthritis symptoms in mice. This was particularly surprising because Arandjelovic and Ravichandran initially thought that loss of ELMO1 would result in increased inflammation.\u00a0 [<a href=\"http:\/\/news.virginia.edu\/content\/surprise-rheumatoid-arthritis-discovery-points-new-treatment-joint-inflammation?utm_source=VirginiaFeatured&amp;utm_medium=referral&amp;utm_campaign=news\">Read more<\/a>]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kodi Ravichandran, left, and Sanja Arandjelovic led new research into the causes of rheumatoid arthritis flare-ups. Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease.\u00a0 The new findings about rheumatoid arthritis came in an unexpected fashion. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":539,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[4],"tags":[],"class_list":["post-998","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-highlights"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Surprise Rheumatoid Arthritis Discovery Points to New Treatment for Joint Inflammation - Biomedical Sciences Graduate Program<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/bims\/rheumatoid-arthritis-discovery\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Surprise Rheumatoid Arthritis Discovery Points to New Treatment for Joint Inflammation - Biomedical Sciences Graduate Program\" \/>\n<meta property=\"og:description\" content=\"Kodi Ravichandran, left, and Sanja Arandjelovic led new research into the causes of rheumatoid arthritis flare-ups. 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