Instruments in the Mass Spectrometry Core
Thermo Electron LTQ Velos Orbitrap Mass Spectrometer
The first part of this instrument has two linear ion traps for more efficient operation. Species of interest can be analyzed with high accuracy in the Orbitrap section.
Equipped with Collision Induced Dissociation (CID), Electron Transfer Dissociation (ETD), Higher-Energy Collision Dissociation (HCD) and a microspray ion source for complex mixture and PTM analysis as well as relative quantification.
Thermo Electron TSQ Quantum Access MAX
Equipped with Quantitation-Enhanced Data-Dependent MS/MS (QED-MS/MS) and Highly Selective Reaction Monitoring (H-SRM) to provide accurate quantification at low levels for specific molecules of interest.
Adapting this instrument to perform Selective Reaction Monitoring (SRM)/Multiple Reaction Monitoring on small samples started in December 2009
This triple quadrupole instrument is used for quantitation of proteins, peptides, some metabolites.
Bruker MicroFlex MALDI
This instrument measures masses of intact molecules. Sample preparation is usually relatively simple so this instrument is the first choice to obtain the mass of peptides, proteins and some other molecules.
