{"id":3809,"date":"2023-10-06T19:17:32","date_gmt":"2023-10-06T19:17:32","guid":{"rendered":"https:\/\/med.virginia.edu\/cancer-research\/?p=3809"},"modified":"2025-10-21T19:19:59","modified_gmt":"2025-10-21T19:19:59","slug":"molecular-genetics-and-epigenetics-gen-program-pilot-project-awards","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/cancer-research\/2023\/10\/06\/molecular-genetics-and-epigenetics-gen-program-pilot-project-awards\/","title":{"rendered":"Molecular Genetics and Epigenetics (GEN) Program Pilot Project Awards"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-2887 alignright\" src=\"https:\/\/med.virginia.edu\/cancer-research\/wp-content\/uploads\/sites\/438\/2023\/05\/2-1.png\" alt=\"GEN\" width=\"200\" height=\"200\" srcset=\"https:\/\/med.virginia.edu\/cancer-research\/wp-content\/uploads\/sites\/438\/2023\/05\/2-1.png 200w, https:\/\/med.virginia.edu\/cancer-research\/wp-content\/uploads\/sites\/438\/2023\/05\/2-1-150x150.png 150w, https:\/\/med.virginia.edu\/cancer-research\/wp-content\/uploads\/sites\/438\/2023\/05\/2-1-100x100.png 100w, https:\/\/med.virginia.edu\/cancer-research\/wp-content\/uploads\/sites\/438\/2023\/05\/2-1-70x70.png 70w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/>The GEN Program of the UVA Comprehensive Cancer Center provides seed funds for new projects from GEN members that address the accumulation of heritable genetic and epigenetic changes that result in the loss of tumor suppressors and inappropriate activation of proto-oncogenes.\u00a0 The goals of GEN are to understand the molecular mechanisms that underlie these defects to unleash the potential of precision medicine.\u00a0 GEN has a basic science focus and capitalizes on the large number of outstanding investigators at UVA with research expertise in chromatin architecture, transcription, replication, DNA repair, genomics, epigenomics, and cellular checkpoints in cancer.\u00a0 Program members are organized into three thematic areas: <b>1) chromosome function, malfunction, and cellular checkpoints; 2) changes in gene expression and epigenetics that drive cancer; <\/b>and<b> 3) cancer bioinformatics.<\/b><\/p>\n<p><b>Award:<\/b>\u00a0 Up to $50,000 (direct costs only) for 1 year.<\/p>\n<p><b>Eligibility: <\/b>This award is open to UVA faculty. Team applications are encouraged and must include at least one GEN member.<\/p>\n<p><b>Deadline:<\/b> Closed (RFA to be released each June).<\/p>\n<p><b>Contact for Questions: <\/b>Please contact <strong>Hui Li, PhD<\/strong> (<a href=\"mailto:hl9r@virginia.edu\">hl9r@virginia.edu<\/a>) or <strong>Todd Stukenberg, PhD<\/strong> (<a href=\"mailto:pts7h@virginia.edu\">pts7h@virginia.edu)<\/a> with questions and to discuss project alignment.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The GEN Program of the UVA Comprehensive Cancer Center provides seed funds for new projects from GEN members that address the accumulation of heritable genetic and epigenetic changes that result in the loss of tumor suppressors and inappropriate activation of proto-oncogenes.\u00a0 The goals of GEN are to understand the molecular mechanisms that underlie these defects [&hellip;]<\/p>\n","protected":false},"author":1925,"featured_media":2887,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"class_list":["post-3809","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-program-awards"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - 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