Current Graduate Students

Abigail Antoine

aga9gw@virginia.edu
Research Interests:

I am interested in the system-level effects of cell-to-cell communication. Currently, I study how one transmembrane channel, Pannexin 3, affects the intercellular communication between vascular smooth muscle cells and endothelial cells to facilitate constriction and dilation of small resistance arteries.


Christopher Bott

cjb2ma@virginia.edu
Research Interests:

Neurons are one of the most dramatic examples of polarized cell morphology during mammalian development. I study the dynamics and coordination of the neuronal cytoskeleton that contributes to this polar asymmetry.


Danielle Dacrema

dfdh8f@virginia.edu
Research Interests:

The epithelial barrier provides a dynamically regulated diffusion barrier, but little is understood about how this regulation occurs; I use Drosophila larvae as a model to study epithelial barrier regulation during regeneration.


Adam Greene

arg7ef@virginia.edu
Research Interests:

I am interested in studying the host-pathogen relationships involving invasive bacterial pathogens and understanding how perturbations in host homeostasis leads to disease. Currently, I am studying how Salmonella manipulates cholesterol trafficking within host macrophages to facilitate bacterial survival and the mechanisms through which this occurs.


Xavier Horton

xmh8t@Virginia.EDU
Research Interests:

Of the extracellular tear proteins downregulated in dry eye disease, lacritin is the only one known to trigger basal tearing and restore ocular homeostasis. I am interested in elucidating signaling mediators, associated receptor complexes, and ion channels activated through lacritin signaling.


Faith Karanja

fwk3bu@Virginia.EDU
Research Interests:

Loss of regenerative capacity often coincides with changes in systemic hormonal signaling. Using Drosophila larvae as a model, I study the role of hormonal signaling in regulating the timing and morphology of the regenerative response to damage.


Jinwoo Lee

jl9bu@virginia.edu
Research Interests:

I am interested in understanding the signaling events that lead to the formation and patterning of the mammalian nervous system. I work with mouse embryoid bodies and try to recapitulate the neural developments in vitro by engineering morphogen gradients.


Katrina McNeely

ko4ek@Virginia.EDU
Research Interests:

The Dwyer lab is interested in neural development, and we focus on the unique cell division that neural progenitors undergo.  My project centers around the Kinesin-6 family member Kif20b.  Kif20b is involved in the final stage of cell division, abscission.  I am using a loss of function mouse model of Kif20b to elucidate the importance of abscission timing in controlling the size of the brain.


Jessica Neville Little

jln3az@virginia.edu
Research Interests:

The cerebral cortex is formed from neural progenitors that undergo highly specified divisions to form all the neurons and glia of the brain. I study the timing, localization and symmetry of these divisions and the effects they have on cell fate and neuron development.


Prasad Trivedi

pvt4ja@virginia.edu
Research Interests:

I am interested in elucidating molecular pathways ensuring faithful genome segregation during mitosis. Currently, I am trying to figure out how proper kinetochore-microtubule attachment formation in regulated and how and the spindle assembly checkpoint is maintained in absence of proper kinetochore-microtubule attachment.


Tan Truong

tmt2wv@Virginia.EDU
Research Interests:
Insulin acts on cells expressing homo- and/or hetero-dimers of insulin-receptive transmembrane proteins. I am establishing a method to create live cells expressing a uniform population of insulin receptor heterodimers in order to unambiguously study their molecular and morphological consequences in various pathologies.

Jacob Wolpe

jbw8a@Virginia.EDU
Research Interests:

TBA