{"id":106403,"date":"2023-06-15T11:33:48","date_gmt":"2023-06-15T15:33:48","guid":{"rendered":"https:\/\/med.virginia.edu\/cell-biology\/?p=106403"},"modified":"2026-05-21T12:28:34","modified_gmt":"2026-05-21T16:28:34","slug":"nafiisha-genet-receives-aha-career-development-award","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/cell-biology\/2023\/06\/15\/nafiisha-genet-receives-aha-career-development-award\/","title":{"rendered":"Nafiisha Genet Receives AHA Career Development Award"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-106402\" src=\"https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-200x300.jpg\" alt=\"Nafiisha Genet\" width=\"200\" height=\"300\" srcset=\"https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-200x300.jpg 200w, https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-683x1024.jpg 683w, https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-768x1152.jpg 768w, https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-1024x1536.jpg 1024w, https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-1365x2048.jpg 1365w, https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-133x200.jpg 133w, https:\/\/med.virginia.edu\/cell-biology\/wp-content\/uploads\/sites\/193\/2023\/06\/Nafiisha-Genet-scaled.jpg 1707w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>Nafiisha Genet, newly appointed Research Assistant Professor in the Hirschi Lab, has been awarded a prestigious Career Development Award from the American Heart Association (AHA).\u00a0Her\u00a0recent published\u00a0study\u00a0in Cell Reports\u00a0(April 2023)\u00a0revealed that\u00a0connexin 43 (Cx43)-mediated neurovascular interactions in the adult brain neural stem cell niche is an important regulator of neural stem cell activation.\u00a0Her study shows\u00a0that loss of\u00a0Cx43 in either neural stem cells or\u00a0endothelial cells\u00a0leads\u00a0to neural stem cell activation and proliferation.\u00a0For her newly funded Career Development Award,\u00a0she\u00a0aims to\u00a0study\u00a0the role of endothelial- and\u00a0astroglial-expressed Cx43 in retinal vascular development and retinopathies, namely\u00a0retinopathy of prematurity\u00a0and diabetic retinopathy. Both diseases are\u00a0characterized by astrocytic death\u00a0and\u00a0changes in the retinal microvasculature\u00a0that ultimately lead to blindness.\u00a0Dr. Genet\u2019s project will provide\u00a0insights into\u00a0Cx43-based neurovascular interactions in the developing retinal\u00a0vasculature\u00a0and\u00a0will\u00a0determine whether modulating Cx43 expression and\/or function with Cx43 mimetic peptides can prevent or correct pathological neovascularization in retinopathies, opening a new avenue for devising therapeutic strategies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Nafiisha Genet, newly appointed Research Assistant Professor in the Hirschi Lab, has been awarded a prestigious Career Development Award from the American Heart Association (AHA).\u00a0Her\u00a0recent published\u00a0study\u00a0in Cell Reports\u00a0(April 2023)\u00a0revealed that\u00a0connexin 43 (Cx43)-mediated neurovascular interactions in the adult brain neural stem cell niche is an important regulator of neural stem [&hellip;]<\/p>\n","protected":false},"author":1740,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[4],"tags":[21],"class_list":["post-106403","post","type-post","status-publish","format-standard","hentry","category-news-and-highlights","tag-delete"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - 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