Equipment in research cores

Major equipment in the School of Medicine research cores

EquipmentUseOperated byLocation*Core
Operetta High-Content Imaging SystemIt can acquire, analyze and manage fluorescence, brightfield and digital phase contrast imagesCore or ResearcherOMS 4806Advanced Microscopy Facility
LSM 710Core or ResearcherOMS 4806Advanced Microscopy Facility
Zeiss Sigma VP HD FE-SEM
Core or ResearcherOMS 4806Advanced Microscopy Facility
Zeiss LSM700 confocal microscopeCore or ResearcherOMS 4806Advanced Microscopy Facility
LSM 880 Confocal with AiryscanReads 10 dyes simultaneously, high sensitivity detector, environmental chamber for live cell imagingCore or ResearcherOMS 4806Advanced Microscopy Facility
JOEL JEM-1230 TEMCore or ResearcherOMS 4806Advanced Microscopy Facility
Olympus BX51Brightfield, Fluorescence, Phase Contrast and DICCore or ResearcherOMS 4806Advanced Microscopy Facility
Leica Thunder with TIRFCore or ResearcherOMS 4806Advanced Microscopy Facility
Olympus SZX12 dual objective stereo microscope with digital cameraBrightfield, Darkfield and FluorescenceCore or ResearcherOMS 4806Advanced Microscopy Facility
High Resolution Vacuum Evaporator for rotary shadowingmetal coatingCore or ResearcherOMS 4806Advanced Microscopy Facility
Leica Ultracut Ultramicrotomes (3)Core or ResearcherOMS 4806Advanced Microscopy Facility
Critical Point DryerCore or ResearcherOMS 4806Advanced Microscopy Facility
Sputter CoaterCore or ResearcherOMS 4806Advanced Microscopy Facility
fluorescent plate readerassays using fluorescent reagents in 6 to 384 well plates
researcherPinn 1074 (BAF)
circular dichroism spectropolarimeter, JASCO J-1500secondary structure of proteins, including melting studiesresearcher Pinn 1074 (BAF)
Bio-Rad GS-800 densitometerscanning X-ray type films, gels stained with visible stains like Coomassie and silverresearcherPinn 1074 (BAF)
Aperio ScanScopebrightfield scanning of microscopy slide to digital images at magnifications of 20X, 40X, 63X for digital pathologycore or researcherPinn 1074 (BAF)
Biotek ELx800 absorbance plate readerabsorbance measurements on microtiter plates at 450, 562, 600, 660 nmresearcherPinn 1074 (BAF)
Dionex HPLC system for 0.3 to 4.6 mm diameter columnsanalysis of small samples of peptides, proteins and other moleculescorePinn 1051 BAF)
fortéBIO Octet96molecular interactions using BioLayer Interferometry
researcherPinn 1074 (BAF)
ImageQuant Tl softwarerelative quantitation of bands on gels and filmresearcherPinn 1074 (BAF)
Matrix Assisted Laser Desorption Ionization-Time Of Flight mass spectrometer (MALDI-TOF), Bruker Microflexmeasure mass of intact molecules, normally peptides, protein, also small pieces of DNA, other moleculescore or researcher
Pinn 1105 (BAF)
Acea xCELLigence RTCA real time cell analysis instrumentreal time, continuous measurement of cellular activity, including migration, based on impedance measurements
researcherPinn 1051 BAF)
Thermo Scientific Q Exactive HF-Xidentification and sequencing of proteins; proteomics, analysis of other biomoleculescore
Pinn 1105 (BAF)
Computing clusters, dedicated access, 32 cores, 252GB RAMComputational infrastructure that is essential for analyzing high-throughput biological dataBioinformatics/maintained by UVA ITSUniversity Data Center
OLD IVY
Bioinformatics
Computing clusters, dedicated access, 55 cores, 378GB RAMComputational infrastructure that is essential for analyzing high-throughput biological dataBioinformatics/maintained by UVA ITSUniversity Data Center
OLD IVY
Bioinformatics
Computing clusters, dedicated access, 72 cores, 378GB RAMComputational infrastructure that is essential for analyzing high-throughput biological dataBioinformatics/maintained by UVA ITSUniversity Data Center
OLD IVY
Bioinformatics
Bruker Avance III NMR spectrometer 800MHz with HCN Zpfg cryoprobePerforms wide range of solution NMR experimentsCore or ResearcherChem 138BioNMR
Bruker Avance III NMR spectrometer 600MHz with HCN Zpfg probePerforms wide range of solution NMR experimentsCore or ResearcherChem 138BioNMR
Varian NMRS 600 spectrometer with multiple probesPerforms wide range of solution NMR experimentsCore or ResearcherChem 122BioNMR
Varian NMRS 600 spectrometer with multiple probesPerforms wide range of solution NMR experimentsCore or ResearcherChem 175BioNMR
Varian Inova 500 NMR spectrometer with multiple probesPerforms wide range of solution NMR experimentsCore or ResearcherChem 175
BioNMR
Arcturus (Life Technologies) XT-TI laser microdissection apparatusmicro scale dissection of fixed or frozen tissue under bright-field, phase contrast or fluorescence visualizationresearcherMR6 B703Biorepository & Tissue Research Facility
Pathology Devices TMArrayer semi-automated tissue microarray apparatusSemi-automated construction of tissue microarraysCoreMR6 G714Biorepository & Tissue Research Facility
QIAGEN QIAcube robotic workstationfully automated protein and nucleic acid extractionCoreMR6 G710Biorepository & Tissue Research Facility
Next Advance Bullet Blender tissue homogenizertissue disruption/homogenization for fresh, frozen or fixed tissueCoreMR6 G712Biorepository & Tissue Research Facility
Miltenyi Biotech gentleMACS™ DissociatorFresh tissue dissociation for viable cellsCoreMR6 G712Biorepository & Tissue Research Facility
Bio-Rad iMark Absorbance Microplate Reader96-well format plate reader; available filters 415,450,595,620,655,750 nmCore or ResearcherMR6 G712Biorepository & Tissue Research Facility
DAKO Autostainer PlusAutomated immunohistochemistry platformCore MR6 G710Biorepository & Tissue Research Facility
DAKO PT Link pretreatment moduleSemi-automated depariffinization and antigen retrieval for immunohistochemistryCore MR6 G710Biorepository & Tissue Research Facility
Olympus BX41TF with 12 megapixel Digital Camera and Olympus Microsuite PathologyBright-field photomicroscopy and remote collaborationCore or ResearcherMR6 G712Biorepository & Tissue Research Facility
Sakura Finetek VIP5 ProcessorAutomated processing of formalin-fixed tissueCore MR6 G714Biorepository & Tissue Research Facility
Sakura Finetek Tissue-Tek TECPreparation of paraffin blocksCore MR6 G714Biorepository & Tissue Research Facility
Microm HM 325 with histocollimatorMicrotome for sectioning paraffin blocks and tissue microarraysCore MR6 G714Biorepository & Tissue Research Facility
MVE-Chart vapor phase LN2 freezersCryogenic biospecimen storageCore MR6 B501BBiorepository & Tissue Research Facility
-30º C freezerbiospecimen storage
Core MR6 G701ABiorepository & Tissue Research Facility
-80º C freezersbiospecimen storage
Core MR6 (Multiple Locations)Biorepository & Tissue Research Facility
QIAGEN TissueLyser IITissue disruption/homogenization for fresh, frozen or fixed tissueCoreMR6 G710Biorepository & Tissue Research Facility
Thermo CryoStarNX50Preparation of frozen tissue sectionsCore or ResearcherMR6 G714Biorepository & Tissue Research Facility
Hamamatsu Nanozoomer S360Digital pathology: high-throughput whole slide scanning (brightfield)CoreMR6 G714Biorepository & Tissue Research Facility
Pathcore Flow image management systemDigital pathology: web-based image storage, collaboration, & sharingCore or ResearcherMR6 G714Biorepository & Tissue Research Facility
Visiopharm ONCOTOPIX softwareDigital pathology: whole slide, multi-color image analysisCoreMR6 G714Biorepository & Tissue Research Facility
Nexcelom Cellometer Auto 2000 Automatic Cell Viability Counter systemFluorescence-based cell countingCoreMR6 G712Biorepository & Tissue Research Facility
Agilent 4150 TapestationLabchip-based RNA/DNA quality assessmentCoreMR6 G710Biorepository & Tissue Research Facility
NanoDrop One Flash SpectrophotometerMicroliter volume direct read quantitation of nucleic acid solutionsCore or ResearcherMR6 G712Biorepository & Tissue Research Facility
NanoDrop 3300 FluorospectrometerMicroliter volume dye-based quantitation of nucleic acid solutionsCore or ResearcherMR6 G712Biorepository & Tissue Research Facility
Ventana Discovery UltraAutomated immunohistochemistry and chromogenic RNA in-situ platformCoreMR6 G710Biorepository & Tissue Research Facility
StatSpin CytoFuge 2Creation of cytospin cytology prepsCoreMR6 G710Biorepository & Tissue Research Facility
10X Genomics Chromium ControllerSingle Cell RNA Seq, single nuclei ATAC-seq and single cell proteogenomicsCorePinn 1076Genome Analysis Technology Core
Illumina MiSeq sequencing systemSmall genome sequencing, targeted gene sequencing, 16S metagenomics, and library QCCorePinn 1044Genome Analysis Technology Core
Illumina NextSeq sequencing system
Broad genomics sequencing applications including RNA-Seq (bulk and single cell), whole exome sequencing, high throughput metagenomics and targeted resequencingCorePinn 1044Genome Analysis Technology Core
Applied Biosystems Prism QuantStudio 6 Flex Real Time PCR SystemReal time PCR for gene expression and genotyping applications. Core Pinn 1076Genome Analysis Technology Core
Agilent Bioanalyzer
Capillary electrophoresis of small samples of DNA and RNA for quality controlCore or ResearcherPinn 1076Genome Analysis Technology Core
NanoVue Spectrophotometer
Measuring absorbances of small volumes, especially quantitation of DNACore Pinn 1076Genome Analysis Technology Core
Qubit fluorometerQuantitating small samples of DNA and RNA by fluorescenceCore or ResearcherPinn 1044Genome Analysis Technology Core
Bio-Rad QX200™ Droplet Digital™ PCR SystemAbsolute quantitation of DNA and RNACore or ResearcherPinn 1076Genome Analysis Technology Core
Sage Pippin PrepPreparation of libraries for NGS using agaroe gel electrophoresis to isolate the desired size(s)ResearcherPinn 1076Genome Analysis Technology Core
Covaris S2Shear DNA to sizes suitable for sequencingResearcherPinn 1076Genome Analysis Technology Core
Agilent Tape StationQC instrument for RNAs and DNA. It is used to determine RNA integrity number (RIN) and for sizing NGS libraries prior to sequencingCore or ResearcherPinn 1076Genome Analysis Technology Core
Vyaire VmaxClinical measurement of oxygen consumption during exerciseCoreCollins 2406Exercise Physiology Core Laboratory
BOD POD GS Body Composition tracking system (COSMED)Air displacement plethysmography system for determining body composition, e.g. fat free tissue and fat tissueCoreCollins 2406Exercise Physiology Core Laboratory
GE Case Exercise Testing System including ECG and TreadmillClinical measurement of oxygen consumption during exerciseCoreCollins 2406Exercise Physiology Core Laboratory
Monark Arm Crank ErgometerUpper body ergometerCoreCollins 2406Exercise Physiology Core Laboratory
Quinton Q-Stress ECG systemElectrocardiograph for exercise testing; compatible with Lode ergometerCoreCollins 2406Exercise Physiology Core Laboratory
Lode Corival BikeElectronically calibrated research ergometerCoreCollins 2406Exercise Physiology Core Laboratory
Brachial Analyzer (MIA Vascular Research Tools 5) software
Medical image analysis software for the assessment of FMD/endothelial function of brachial artery from ultrasound image data.CoreCollins 2406Exercise Physiology Core Laboratory
Attune™ NxThigh throughput cytometry with 4 lasers, 14 colors and autosamplerCorePinn 2013 (FCCF)
Becton Dickinson FACSVantage SE Turbo Sorter with DIVA cell sorter10 color, 4 way sorting, sterile sorting, BSL2 materials, with 3 lasersCorePinn 2013 (FCCF)
Becton Dickinson Fortessa LSRII benchtop analyzer4 lasers, 17 detectors at up to 30,000 cells/sec
core or researcherPinn 2011 (FCCF)
Becton Dickinson/Cytek FACSCalibur Benchtop Analyzer3 laser, 5 color analysescore or researcherPinn 2011 (FCCF)
Becton Dickinson/Cytek FACSCalibur Benchtop Analyzer4 laser, 10 color analyses with Automated Micro-Sampler system for 96 well platescore or researcherPinn 2011 (FCCF)
Becton Dickinson/Cytek FACSCalibur Benchtop Analyzer2 laser, 4 color analysescore or researcherPinn 2011 (FCCF)
Becton Dickinson/Cytek FACSCalibur Benchtop Analyzer2 laser, color analysesresearcherPinn 2011 (FCCF)
Amnis ImagestreamX Mark IIimaging cytometer, for dark field, bright field and fluorescent images with 4 lasers, 12 channels, 20X, 40X, 60X magnifications, 96 well plate automationcore or researcherPinn 2011 (FCCF)
Luminex MAGPIX®measures multiple analytes such as chemokines from mouse or human samplePinn 2011 (FCCF)
BD Influx cell sorter for BSL2 samples in custom Baker biosafety cabinet6 way sorting of BSL2 samples using 5 lasers, 15 colorscorePinn 2013 (FCCF)
FACSAria™ Fusionsorting of BSL2 samples with 5 lasers, 15 colors, 4 way sorting(FCCF)
Fluidigm CyTOF 2 Heliosanalysis of multiple parameters at single cell levelcorePinn 2013 (FCCF)
AutoMACS Pro
Isolation of cell populations labelled with 50 nm superparamagnetic particles conjugated to antibodies to cell surface antigensresearcherPinn 2011 (FCCF)
Data analysis work station (5)
4 Mac stations and 1 PC with FloJo and Modfit softwareresearcherPinn 2011 (FCCF)
Leica DM IRB inverted microscopesCoreOMS 1845Genetically Engineered Murine Model Core
Leitz micromanipulatorsCoreOMS 1845Genetically Engineered Murine Model Core
Sutter P-87 micropipette puller
CoreOMS 1845Genetically Engineered Murine Model Core
De Fonbrune microforgeCoreOMS 1845Genetically Engineered Murine Model Core
Bio-Cool BCIV40A Controlled-Rate FreezerCoreOMS 1845Genetically Engineered Murine Model Core
XYClone laser systemCoreOMS 1845Genetically Engineered Murine Model Core
NEPA21 type II super electroporatorCoreOMS 1845Genetically Engineered Murine Model Core
Primetech PMM4G piezo micro manipulatorCoreOMS 1845Genetically Engineered Murine Model Core
Eppendorf femtojet 4i electronic microinjectorCoreOMS 1845Genetically Engineered Murine Model Core
BTX ECM630 ElectroporatorCorePinn 2223Genetically Engineered Murine Model Core
Eppendorf EP Gradient MastercyclerCorePinn 2223Genetically Engineered Murine Model Core
UVIdoc LCD Gel Documentation SystemCorePinn 2223Genetically Engineered Murine Model Core
FEI Tecnai™ Spirittransmission electron microscopy of negatively stained samples, cryo-electron microscopyresearcherLife Sciences Annex, Snyder (MEMC)
FEI Tecnai™ F20
cryo-electron microscopy (moderate resolution), high resolution negative stain electron microscopyresearcherLife Sciences Annex, Snyder (MEMC)
FEI Titan Krioshigh resolution cryo-electron microscopyresearcherLife Sciences Annex, Snyder (MEMC)
FEI Vitrobotsample vitrification for cryo-transmission electron microscopyresearcherLife Sciences Annex, Snyder (MEMC)
7 Tesla Bruker/Siemens ClinScan small animal MRIMRI scans of small animalscore or researchMR4 1184 (MIC)
Caliper IVIS Spectrum bioluminescence and fluorescence scannerfluorescence and luminescence scanner for tissue samplesfluorescence and luminescence scanner for tissue samplescore or researchSnyder (MIC)
Bruker Aibira Si trimodal PET/SPCET/CT scannerscan small animals using positron emission, gamma emission and X-rays with sub-millimeter resolutionSnyder (MIC)
Siemens Eclipse Cyclotron
production of isotopes for PET scanningcore and Siemens/PETNETSnyder (MIC)
Radiochemistry modulessynthesis of radiolabelscore
ultrasound scannerultrasound imaging
Tissue processors for formalin and Bouin’s fixed tissuescoreMR5 1035 (RHC)
tissue embedding stationMR5 1035 (RHC)
microtomespreparing thin sections for microscopycoreMR5 1035 (RHC)
stainer, automatedstaining of tissue sectionscoreMR5 1035 (RHC)
cryostatpreparing frozen tissue sections for microscopycoreMR5 1035 (RHC)
Lonza 4D Nucleofector with X unittransfection of mammalian cellsCore or ResearcherPinn 1071 (SCC)
Inverted microscopes, Axio and OlympusCore or ResearcherPinn 2034Tissue Culture Facility
Olympus IM microscopeCore or ResearcherPinn 2034Tissue Culture Facility
CO2 incubatorsCore or ResearcherPinn 2034Tissue Culture Facility
IncubatorsMaintenance of insect cell linesCore Pinn 2034Tissue Culture Facility
cold storage, liquid nitrogenCell storageCore Pinn 2034Tissue Culture Facility
Biosafety cabinets (2)Cell culturePinn 2034Tissue Culture Facility

Core abbreviations: AMF, Advanced Microscopy Facility; BAF, Biomolecular Analysis Facility; BioNMR, Biomolecular Magnetic Resonance Facility; BTRF, Biorepository and Tissue Research Facility; GATC, Genome Analysis and Technology Core; EPCL, Exercise Physiology Core Laboratory; FCCF, Flow Cytometry Core Facility; GEMM, Genetically Engineered Murine Model Core; MEMC, Molecular Electron Microscopy Core; MIC, Molecular Imaging Core; RHC, Research Histology Core; TCF, SCC, Stem Cell Core; Tissue Culture Facility.*Location information is building name and room number. MSB, Medical School Building. Pinn Hall was formerly called Jordan Hall