List of Equipment in Research Cores-table

Equipment

Uses

Core

Use type

Building

Room

JEOL 1230 transmission electron microscope, real-time digital imaging (2Kx2K),  ultra high resolution digital imaging (4Kx4K), film imaging. Advanced Microscopy Facility core or user operated Old Medical School 4806
Zeiss Sigma VP HD field emission SEM scanning electron microscope Advanced Microscopy Facility core or user operated Old Medical School 4806
Zeiss LSM 510 META/FCS confocal microscope, inverted, with 3 channels and a programmable detector Advanced Microscopy Facility core or user operated West Complex Center for Cell Signaling
Zeiss LSM 700 confocal microscope, inverted, with 4 channels, ZEN software Advanced Microscopy Facility core or user operated Old Medical School 4806
Zeiss LSM 710 Zeiss LSM 710 Multiphoton confocal. upright, 4 channels, 6 laser lines, Coherent Chameleon IR laser, Advanced Microscopy Facility core or user operated Old Medical School 4809
Zeiss LSM 880 Zeiss LSM 880. Reads 10 dyes simultaneously, high sensitivity detector, environmental chamber for live cell imaging Advanced Microscopy Facility core or user operated MR4 5136
Leica Ultracut UC7 ultramicrotome preparation of samples for transmission electron microscopy Advanced Microscopy Facility core or user operated Old Medical School 4806
Olympus BX51 with digital camera Brightfield, Fluorescence, Phase Contrast and DIC Advanced Microscopy Facility core or user operated Old Medical School 4806
Olympus SZX12 dual objective stereo microscope with digital camera Brightfield, Darkfield and Fluorescence Advanced Microscopy Facility core or user operated Old Medical School 4806
High Resolution Vacuum Evaporator for rotary shadowing metal coating Advanced Microscopy Facility core or user operated Old Medical School 4806
Leica Ultracut Ultramicrotomes (3) Advanced Microscopy Facility core or user operated Old Medical School 4806
Critical Point Dryer Advanced Microscopy Facility core or user operated Old Medical School 4806
Sputter Coater Advanced Microscopy Facility core or user operated Old Medical School 4806
Computing clusters, dedicated access, 8 cores, 128GB RAM Bioinformatics Core
Computing cluster, shared access, over 1500 cores, over 3TB RAM Bioinformatics Core
Ingenuity Pathway Analysis, Oncomine Premium subscription based bioinformatics software Bioinformatics Core
Bioconductor software for bioinformatics and statistical computing, over 600 packages Bioinformatics Core
Bruker Avance III NMR spectrometer 800MHz Biomolecular Magnetic Resonance Facility core or user operated Chemistry 133
Bruker Avance III NMR spectrometer 600MHz Biomolecular Magnetic Resonance Facility core or user operated Chemistry 133
Bruker Avance DRX NMR spectrometer 600MHz Biomolecular Magnetic Resonance Facility core or user operated Chemistry 106
Varian NMRS  spectrometer 600MHz Biomolecular Magnetic Resonance Facility core or user operated Chemistry 111
Varian Inova 500 NMR spectrometer 500MHz Biomolecular Magnetic Resonance Facility core or user operated Chemistry 175
Leica ASLMD laser microdissection apparatus micro scale dissection of fixed or frozen tissue Biorepository and Tissue Research Facility user operated MR6 G712
Arcturus (Life Technologies) XT-TI laser microdissection apparatus micro scale dissection of fixed or frozen tissue under bright-field, phase contrast or fluorescence visualization Biorepository and Tissue Research Facility user operated MR6 G712
Pathology Devices TMArrayer semi-automated tissue microarray apparatus production of tissue microarrays Biorepository and Tissue Research Facility core operated MR6 G710
QIAGEN QIAcube robotic workstation fully automated protein and nucleic acid extraction Biorepository and Tissue Research Facility core operated MR6 G712
Promega Maxwell16 robotic workstation fully automated protein and nucleic acid extraction Biorepository and Tissue Research Facility core operated MR6 G712
QIAGEN TissueLyser II tissue disruption/homogenization for fresh, frozen or fixed tissue Biorepository and Tissue Research Facility core operated MR6 G712
Next Advance Bullet Blender tissue homogenizer tissue disruption/homogenization for fresh, frozen or fixed tissue Biorepository and Tissue Research Facility core operated MR6 G712
Miltenyi Biotech gentleMACS™ Dissociator fresh tissue dissociation for viable cells Biorepository and Tissue Research Facility core operated MR6 G712
Bio-Rad iMark Absorbance Microplate Reader 96-well format plate reader; available filters 415,450,595,620,655,750 nm Biorepository and Tissue Research Facility core or user operated MR6 G712
Bio-Rad Experion microcapillary electrophoresis system microscale/LabChip RNA and DNA analysis Biorepository and Tissue Research Facility core operated MR6 G712
NanoDrop spectrophotometer microscale DNA and RNA quantitation Biorepository and Tissue Research Facility core or user operated MR6 G712
DAKO Autostainer/Autostainer Plus automated immunohistochemistry platform Biorepository and Tissue Research Facility core operated MR6 G712
DAKO PT Link pretreatment module semi-automated depariffinization and antigen retrieval for immunohistochemistry Biorepository and Tissue Research Facility core operated MR6 G712
Leica 3050S research cryostat preparation of frozen tissue sections Biorepository and Tissue Research Facility core or user operated MR6 G710
Olympus BX41TF with 12 megapixel Digital Camera and Olympus Microsuite Pathology bright-field photomicroscopy and remote collaboration Biorepository and Tissue Research Facility core or user operated MR6 G712
Nikon COOLSCOPE bright-field photomicroscopy Biorepository and Tissue Research Facility core or user operated MR6 B520
Leica SCN400 digital whole-slide scanner with SlidePath Digital Image Hub, Tissue IA, and OpTMA Module bright-field whole slide imaging, image analysis, and tissue microarray de-arraying, annotation, and analysis Biorepository and Tissue Research Facility core operated MR6 B703
Sakura Finetek VIP5 Processor automated processing of formalin-fixed tissue Biorepository and Tissue Research Facility core operated MR6 G710
Sakura Finetek Tissue-Tek TEC preparation of paraffin blocks Biorepository and Tissue Research Facility core operated MR6 G710
Microm HM 325 with collimator microtome for sectioning paraffin blocks and tissue microarrays Biorepository and Tissue Research Facility core operated MR6 G710
MVE-Chart 1536P vapor phase LN2 freezers vapor phase biospecimen storage Biorepository and Tissue Research Facility core operated MR6 B501
-30º C freezer biospecimen storage Biorepository and Tissue Research Facility core operated MR6 G701A
-80º C freezers biospecimen storage Biorepository and Tissue Research Facility core operated MR6 G701A
Applied Biosystems 3730 DNA analyzer Sanger sequencing of DNA; SNPlex®; genotyping DNA Sciences core operated Jordan 1044
Illumina genome analyzer analysis of whole chromosomes, targeted genomic regions, BACS, whole genomes, gene expression, small RNA discovery. DNA Sciences core operated Jordan 1044
Illumina MiSeq sequencing system small, rapid next gen sequencing projects DNA Sciences core operated Jordan 1044
Applied Biosystems Prism 7900HT sequence Detection System real time PCR DNA Sciences core operated Jordan 1076
Affymetrix Gene Chip System studying changes in gene expression DNA Sciences core operated Jordan 1071
Agilent Bioanalyzer capillary electrophoresis of small samples of DNA and RNA for quality control DNA Sciences core operated Jordan 1076
NanoVue Spectrophotometer measuring absorbances of small volumes, especially quantitation of DNA DNA Sciences core operated Jordan 1076
QIAcube DNA/RNA purification apparatus nucleic acid extraction DNA Sciences core operated Jordan 1076
Bio-Rad QX200™ Droplet Digital™ PCR System absolute quantitation of DNA and RNA DNA Sciences core operated Jordan 1076
SensorMedics Vmax Metabolic Stress Testing Systems Clinical measurement of oxygen consumption during exercise Exercise Physiology Core Barringer Wing 5527
BOD POD GS Body Composition tracking system (COSMED) Air displacement plethysmography system for determining body composition, e.g. fat free tissue and fat tissue Exercise Physiology Core Barringer Wing 5527
GE Case Exercise Testing System including ECG and Treadmill Clinical measurement of oxygen consumption during exercise Exercise Physiology Core Barringer Wing 5527
Monark Arm Crank Ergometer Upper body ergometer Exercise Physiology Core Barringer Wing 5527
SensorMedics Deltatrac Bedside Metabolic System Measurement of basal or resting metabolism Exercise Physiology Core Barringer Wing (mobile use) 5527
Quinton Q-Stress ECG system Electrocardiograph for exercise testing; compatible with Lode ergometer Exercise Physiology Core Barringer Wing 5527
Lode Bicycle Ergometer Electronically calibrated research ergometer Exercise Physiology Core Barringer Wing 5527
Specialty Software
sliceOmatic (TomoVision) Medical image analysis software for measurement, segmentation and analyzes of multi-slice scanner data. Exercise Physiology Core Barringer Wing 2406
Brachial Analyzer (MIA Vascular Research Tools 5) Medical image analysis software for the  assessment of FMD/endothelial function of brachial artery  from ultrasound image data. Exercise Physiology Core Barringer Wing 2406
Becton Dickinson FACSVantage SE Turbo Sorter with DIVA option 4 way sorting,  sterile sorting,  BSL2 materials, with 3 lasers Flow Cytometry Facility core operated Jordan 2013
Becton Dickinson Fortessa LSRII benchtop analyzer 4 lasers, 16 color analyses at up to 30,000 cells/sec Flow Cytometry Facility core or user operated Jordan 2011
Becton Dickinson/Cytek FACSCalibur Benchtop Analyzer 5 color analyses Flow Cytometry Facility core or user operated Jordan 2011
Becton Dickinson/Cytek FACSCalibur Benchtop Analyzer
10 color analyses with Automated Micro-Sampler system for 96 well plates Flow Cytometry Facility core or user operated Jordan 2011
Becton Dickinson FACSCalibur Benchtop Analyzer 4 color analyses Flow Cytometry Facility core or user operated Jordan 2011
Becton Dickinson FACSCalibur Benchtop Analyzer 4 color analyses Flow Cytometry Facility user operated Jordan 2011
Beckman Coulter CyAn ADP LX 9 Color 9 color analysis at up to 30,000 cells/sec Flow Cytometry Facility core or user operated Jordan 2011
Amnis ImagestreamX Mark II imaging cytometer, for dark field, bright field and fluorescent images with 4 lasers, 12 channels, 20X, 40X, 60X magnifications, 96 well plate automation Flow Cytometry Facility core or user operated Jordan 2011
Luminex® 100™  System measures multiple analytes using multiple assay formats Flow Cytometry Facility core or user operated Jordan 2011
Luminex MAGPIX® measures multiple analytes such as chemokines from mouse or human sample Flow Cytometry Facility core or user operated Jordan 2011
BD Influx cell sorter for BSL2 samples in custom Baker biosafety cabinet sorting of BSL2 samples using 5 lasers, 15 colors Flow Cytometry Facility core operated Jordan 2013
Becton Dickinson Influx cell sorter for BSL3 sorting of BSL3 samples with 5 lasers, 17 colors Flow Cytometry Facility core operated MR6 BSL3 facility
DVS Sciences CyTOF 2 analysis of multiple parameters at single cell level Flow Cytometry Facility core operated Jordan 2013
Data analysis work station (5) 4 Mac stations and 1 PC with FloJo and Modfit software Flow Cytometry Facility user operated Jordan 2011
AutoMACS Pro Isolation of cell populations  labelled with 50 nm superparamagnetic particles  conjugated to antibodies to cell surface antigens Flow Cytometry Facility user operated Jordan 2011
Leica DM IRB inverted microscopes Genetically Engineered Murine Model Core core operated MR5 G339
Leitz micromanipulators Genetically Engineered Murine Model Core core operated MR5 G339
Sutter P-87 micropipette puller Genetically Engineered Murine Model Core core operated MR5 G339
De Fonbrune microforge Genetically Engineered Murine Model Core core operated MR5 G339
Bio-Cool BCIV40A Controlled-Rate Freezer Genetically Engineered Murine Model Core core operated MR5 G339
XYClone laser system Genetically Engineered Murine Model Core core operated MR5 G339
BTX ECM630 Electroporator Genetically Engineered Murine Model Core core operated Jordan 2223
Eppendorf EP Gradient Mastercycler Genetically Engineered Murine Model Core core operated Jordan 2223
UVIdoc LCD Gel Documentation System Genetically Engineered Murine Model Core core operated Jordan 2223
Matrix Assisted Laser Desorption Ionization-Time Of Flight mass spectrometer (MALDI-TOF), Bruker Microflex measure mass of intact molecules, normally peptides, protein, also small pieces of DNA, other molecules Mass Spectrometry core or user operated Jordan 1105
Thermo LTQ Velos Orbitrap mass spectrometer determination of peptide sequences for protein identification in complex mixtures of proteins, relative quantitation of proteins in mixtures, identification of phosphorylation sites and other post translational modifications Mass Spectrometry core operated Jordan 1105
Thermo TSQ Quantum Access absolute quantitation of peptides and proteins with appropriate standards.Triple quadrupole machine. Mass Spectrometry core operated Jordan 1105
FEI Tecnai™ Spirit transmission electron microscopy of negatively stained samples, cryo-electron microscopy Molecular Electron Microscopy Core user operated Life Sciences Annex, Snyder Building, Fontaine Park
FEI Tecnai™ F20 cryo-electron microscopy (moderate resolution), high resolution negative stain  electron microscopy Molecular Electron Microscopy Core user operated Life Sciences Annex, Snyder Building, Fontaine Park
FEI Titan Krios high resolution cryo-electron microscopy Molecular Electron Microscopy Core user operated Life Sciences Annex, Snyder Building, Fontaine Park
FEI Vitrobot sample vitrification for cryo-transmission electron microscopy Molecular Electron Microscopy Core user operated Life Sciences Annex, Snyder Building, Fontaine Park
7 Tesla Bruker/Siemens ClinScan small animal MRI MRI scans of small animals Molecular Imaging Core core or user operated MR4 room 1184
4.7 Tesla Varian 200/400 MRI small animal imager with Varian Direct Drive imaging console MRI scans of small animals Molecular Imaging Core core or user operated Snyder Building
Caliper IVIS Spectrum bioluminescence and fluorescence scanner fluorescence and luminescence scanner for tissue samples Molecular Imaging Core core or user operated Snyder Building
Siemens Medical Solutions Focus 120  Micro Positron Emission Tomography scanner scan tissues or small animals using positrons Molecular Imaging Core Snyder Building
Siemens Eclipse  Cyclotron production of isotopes for PET scanning Molecular Imaging Core core operated (Siemens/PETNET) Snyder Building
Radiochemistry modules synthesis of radiolabels Molecular Imaging Core core operated Snyder Building
ultrasound scanner ultrasound imaging Molecular Imaging Core
Tissue processors for formalin and Bouin’s fixed tissues Research Histology Core core operated MR4 1123
tissue embedding station Research Histology Core core operated MR4 1123
microtomes preparing thin sections for microscopy Research Histology Core core operated MR4 1123
stainer, automated staining of tissue sections Research Histology Core core operated MR4 1123
cryostat preparing frozen tissue sections for microscopy Research Histology Core core operated MR4 1123
fluorescent plate reader assays using fluorescent reagents in 6 to 384 well plates Shared Instrumentation user operated Jordan 1074
circular dichroism spectropolarimeter, Aviv 410 secondary structure of proteins, including melting studies Shared Instrumentation user operated Jordan 1074
Bio-Rad FX fluorescent gel scanner scanning gels stained with Sypro Ruby and other fluorescent stains. 3 laser sources, several filters to cover common visible wavelengths. Shared Instrumentation core operated Jordan 232
Dionex HPLC system for 0.3 to 4.6 mm diameter columns analysis of small samples of  peptides, proteins and other molecules Shared Instrumentation core operated Jordan 1051
Amersham FPLC separation of proteins, peptides, and other molecules in aqueous buffers by gel filtration or ion exchange; a steel free system Shared Instrumentation core operated Jordan 232
Bio-Rad GS-800 densitometer scanning X-ray type films, gels stained with visible stains like Coomassie and silver Shared Instrumentation user operated Jordan 1074
ImageQuant Tl software relative quantitation of bands on gels and film Shared Instrumentation user operated Jordan 1074
Aperio ScanScope scanning microscopy slide to digital images at magnifications of 20X, 40X, 63X for digital pathology Shared Instrumentation user operated Jordan 1074
fortéBIO Octet96 molecular interactions using BioLayer Interferometry Shared Instrumentation user operated Jordan 1074
Pharmacia/GE IPGphor isoelectric focusing apparatus, with 18 cm strip holders, Ettan Dalt 6 electrophoresis apparatus isoelectric focusing Shared Instrumentation user operated Jordan 232
Bio-Rad Protean IEF cell, 11 cm, 17 cm, 24 cm strip holders,Criterion Dodeca cell Protean II Xi cell,Protean Plus Dodeca cell isoelectric focusing, 2-D gels Shared Instrumentation user operated Jordan 232
Acea xCELLigence RTCA real time cell analysis instrument real time, continuous measurement of cellular activity, including migration, based on impedance measurements Shared Instrumentation user operated Jordan 1051
Biotek ELx800 absorbance plate reader absorbance measurements on microtiter plates at 450, 562, 600, 660 nm Shared Instrumentation user operated Jordan 1074
Inverted microscopes, Axio and Olympus Tissue Culture Facility core or user operated Jordan 2-34
Olympus IM microscope Tissue Culture Facility core or user operated Jordan 2-34
CO2 incubators Tissue Culture Facility core or user operated Jordan 2-34
Incubators maintenance of insect cell lines Tissue Culture Facility core operated Jordan 2-34
cold storage, -80°C, liquid nitrogen cell storage Tissue Culture Facility core operated Jordan 2-34
Biosafety cabinets (3) cell culture Tissue Culture Facility user operated Jordan 2-34