Molecular Assessments and Preclinical Studies description

The Molecular Assessments and Preclinical Studies (MAPS) Core is a cost-effective preclinical research facility dedicated to investigations of human disease models in rodents and relevant therapeutic drug development systems.  Although the Core’s roots are in cancer investigations, over the years we have expanded services to include investigations into a wide range of disease models.  The MAPS Core is located in the Medical School Building, room 4767 and is available to all University of Virginia investigators. Our services move research projects from the bench or from a patient sample into an in vivo rodent model context, thereby enhancing the translation of UVA investigator discoveries into useful knowledge for clinical therapeutic applications in the effective management of human diseases.  The MAPS Core services are an integral part of the UVA translational and innovation research initiatives.

In order to facilitate the preclinical study needs at the University of Virginia, the considerably experienced and dedicated MAPS Core staff offers Consultation, Animal Use Protocol Support, Project Management, Therapeutic Testing (treatment programs and maximum tolerated dose evaluations), Xenograft Services (subcutaneous, orthotopic, and metastasis), Animal Monitoring, Surgical Services and Training.  The MAPS Core can do all or part of a study for investigators or we can train investigators to do all or part of their study on their own.

Please contact Core Director Marya Dunlap-Brown ( or faculty director Charles Landen ( for further details or to discuss a project.