Diabetes is a complex of disorders characterized by a common final element of hyperglycemia and vascular injury. The pathogenetic differences between type 1 and 2 diabetes are universally recognized, as are the emerging subdivisions of non-insulin dependent diabetes or NIDDM. Common to these is a need to understand the diverse molecular mechanisms that lead to hyperglycemia. All of the various forms of diabetes, arising from differing initiating lesions, share complications, which occur frequently and exact a heavy toll on patients and families.
The Diabetes Center operates in the belief that applying the increasingly sophisticated biochemical, physical, mathematical and molecular biologic tools available to problems relating to the origin of diabetes or its complications will improve the lives of patients with diabetes or patients at risk to developing the disease.
The vision of the Diabetes Center is two-fold.
Second, through the Assay and Animal Characterization Core Laboratory, the Center seeks to implement and if need-be develop for members state-of-the-art methods for studying the pathogenesis and complications of diabetes. First, the Center seeks to foster and support research into the nature of the biologic and clinical problems encompassed by diabetes.
Diabetes Center Core Laboratories
- Assay and Animal Characterization Core
The research focus of the Diabetes Center members includes:
- Pancreatic Islet Biology and Genetics
- The Control of Plasma Glucose in the Clinical Environment
- Insulin Action and Resistance
- Diabetes Complications
The Diabetes Center has previously been supported in part by a Diabetes Endocrine Research Center (DERC) grant from the NIDDK of the NIH.