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Biophysics Faculty

Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer

Molecular Mechanisms for Membrane Transport and Cell Signaling

Biophysical Chemistry: Membrane protein structure, function, and dynamics

Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging

Structure and Function of Macromolecular Complexes Using Electron Microscopy

Super-resolution fluorescence imaging of bacterial cells

Structure and functions of caveolin proteins

Translating our discoveries in the microcirculation to tangible benefits in patients.

Mechanisms by which cells direct and regulate protein targeting to the ER and mitochondria, and how molecular control of cell dormancy impacts health and disease.

Architecture and function of biological membranes

Fusion of secretory vesicles with the plasma membrane. Fusion of viral particles with target membranes during viral infection.

Fundamental mechanisms by which membranes and dietary lipids regulate cell physiology

Composition, Biophysics and Physiology of Cellular Membranes

Systems biology, infectious disease, cancer, toxicology, metabolic engineering

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

Structural Biology of Membrane Proteins

Chromosome segregation and aneuploidy in meiosis and mitosis

Roles of complex signaling networks involved in the regulation of cardiovascular function and disease

Proteoform Systems Biology: proteogenomic approaches to uncover the role of proteomic variation in human disease

Identify the calcium signaling abnormalities that lead to vascular dysfunction and blood pressure elevation in cardiovascular disorders

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions

Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.