Type 1 diabetes and hypoglycemia
Diabetes and Insulin Action
My research is focused on developing an artificial pancreas, understanding the mechanism(s) by which diabetes affects heart function, and defining the role of carotid bodies in the regulation of blood glucose in humans with and without diabetes.
Integrated Carbohydrate Physiology and Translation.
Osteoporosis and bone metabolism; artificial pancreas for type 1 diabetes
Hormonal control of blood pressure and kidney function; renin-angiotensin-aldosterone system; dopominergic system; renal and vascular paracrine systems; cell and molecular biology of vascular hormones.
Osteoporosis, metabolic bone disease, disorders of calcium and vitamin D metabolism
Reproductive Endocrinology; Biomathematical Modeling of the Hypothalamic-Pituitary-Ovarian AxisConditions.
Understanding the mechanisms that regulate glucagon secretion, glucose homeostasis, and growth hormone release. Mathematical modeling of hormone networks. Diabetes, hypoglycemia, artificial pancreas technology.
The Role of Diabetes in Cognitive Decline
Regulation of pituitary gene expression.
Insulin signaling, insulin-regulated membrane trafficking and associated changes in cellular function and whole body physiology
Insulin action, energy metabolism and diabetes complications
Mechanisms of GnRH Regulation of Gonadotropin and Steriod Synthesis; the Etiology of PCOS in Adolescence
Reproductive neuroendocrinology and polycystic ovary syndrome.
Hypertension, obesity, ghrelin and the renin-angiotensin system
Hypothalamic Peptide and Steroid Regulation of Pituitary Gene Transcription; Estrogen Action in Neuroendocrine and Reproductive Tissues; Estrogen Action in Breast Cancer
Endocrine hypertension, angiotensin receptors, renal paracrine hormones
Endocrinology and metabolism, specifically neuroendocrinology and hypothalamic pituitary disease