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Ann L. Beyer

Ann L. Beyer

Professor Emeritus, Microbiology, Immunology, and Cancer Biology

Bio & Overview

Academic Information

Department
Microbiology, Immunology, and Cancer Biology

Primary Education

  • BS, Biochemistry, Centre College, 1973
  • PhD, Molecular Biology, Vanderbilt University; Nashville TN, 1977
  • Postdoc, Molecular Biology, University of Virginia, 1979

Other Appointments

  • Professor, Microbiology, Immunology, and Cancer Biology
  • Professor, MII
  • Professor, BMBG

Other Affiliations

  • Member, Molecular Genetics and Epigenetics Program
  • Professor, BIMS

Research Interests

RNA Analysis

Selected Publications

2015

Zhang, Y., French, S. L., Beyer, A. L., & Schneider, D. A. (2016). The Transcription Factor THO Promotes Transcription Initiation and Elongation by RNA Polymerase I. JOURNAL OF BIOLOGICAL CHEMISTRY, 291(6), 3010-3018. doi:10.1074/jbc.M115.673442

Engel, K. L., French, S. L., Viktorovskaya, O. V., Beyer, A. L., & Schneider, D. A. (2015). Spt6 Is Essential for rRNA Synthesis by RNA Polymerase I. MOLECULAR AND CELLULAR BIOLOGY, 35(13), 2321-2331. doi:10.1128/MCB.01499-14

2014

Soltanieh, S., Osheim, Y. N., Spasov, K., Trahan, C., Beyer, A. L., & Dragon, F. (2015). DEAD-Box RNA Helicase Dbp4 Is Required for Small-Subunit Processome Formation and Function. MOLECULAR AND CELLULAR BIOLOGY, 35(5), 816-830. doi:10.1128/MCB.01348-14

Axt, K., French, S. L., Beyer, A. L., & Tollervey, D. (2014). Kinetic Analysis Demonstrates a Requirement for the Rat1 Exonuclease in Cotranscriptional Pre-rRNA Cleavage. PLOS ONE, 9(2). doi:10.1371/journal.pone.0085703

2013

Harris, B., Bose, T., Lee, K. K., Wang, F., Lu, S., Ross, R. T., . . . Gerton, J. L. (2014). Cohesion promotes nucleolar structure and function. MOLECULAR BIOLOGY OF THE CELL, 25(3), 337-346. doi:10.1091/mbc.E13-07-0377

Lebaron, S., Segerstolpe, A., French, S. L., Dudnakova, T., Alves, F. D. L., Granneman, S., . . . Tollervey, D. (2013). Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly. MOLECULAR CELL, 52(5), 707-719. doi:10.1016/j.molcel.2013.10.017

Viktorovskaya, O. V., Engel, K. L., French, S. L., Cui, P., Vandeventer, P. J., Pavlovic, E. M., . . . Schneider, D. A. (2013). Divergent Contributions of Conserved Active Site Residues to Transcription by Eukaryotic RNA Polymerases I and II. CELL REPORTS, 4(5), 974-984. doi:10.1016/j.celrep.2013.07.044

Johnson, J. M., French, S. L., Osheim, Y. N., Li, M., Hall, L., Beyer, A. L., & Smith, J. S. (2013). Rpd3-and Spt16-Mediated Nucleosome Assembly and Transcriptional Regulation on Yeast Ribosomal DNA Genes. MOLECULAR AND CELLULAR BIOLOGY, 33(14), 2748-2759. doi:10.1128/MCB.00112-13

Zhang, Y., Anderson, S. J., French, S. L., Sikes, M. L., Viktorovskaya, O. V., Huband, J., . . . Schneider, D. A. (2013). The SWI/SNF Chromatin Remodeling Complex Influences Transcription by RNA Polymerase I in Saccharomyces cerevisiae. PLOS ONE, 8(2). doi:10.1371/journal.pone.0056793

2012

McKnight, S., Beyer, A., & Gall, J. (2012). Oscar Miller (1925-2012) RETROSPECTIVE. SCIENCE, 335(6075), 1457. doi:10.1126/science.1220681

2011

Lemay, V., Hossain, A., Osheim, Y. N., Beyer, A. L., & Dragon, F. (2011). Identification of novel proteins associated with yeast snR30 small nucleolar RNA. NUCLEIC ACIDS RESEARCH, 39(22), 9659-9670. doi:10.1093/nar/gkr659

Huber, A., French, S. L., Tekotte, H., Yerlikaya, S., Stahl, M., Perepelkina, M. P., . . . Loewith, R. (2011). Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L. EMBO JOURNAL, 30(15), 3052-3064. doi:10.1038/emboj.2011.221

Anderson, S. J., Sikes, M. L., Zhang, Y., French, S. L., Salgia, S., Beyer, A. L., . . . Schneider, D. A. (2011). The Transcription Elongation Factor Spt5 Influences Transcription by RNA Polymerase I Positively and Negatively. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(21), 18816-18824. doi:10.1074/jbc.M110.202101

2010

French, S. L., Sikes, M. L., Hontz, R. D., Osheim, Y. N., Lambert, T. E., El Hage, A., . . . Beyer, A. L. (2011). Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. MOLECULAR AND CELLULAR BIOLOGY, 31(3), 482-494. doi:10.1128/MCB.00589-10

El Hage, A., French, S. L., Beyer, A. L., & Tollervey, D. (2010). Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. GENES & DEVELOPMENT, 24(14), 1546-1558. doi:10.1101/gad.573310