Brant Isakson

Dunaway, L. S., Saii, K., LoBue, A., Nyshadham, S., Abib, N., Heuser, S. K., . . . Isakson, B. E. (2024). The hemodynamic response to nitrite is acute and dependent upon tissue perfusion.. Nitric oxide : biology and chemistry, 150, 47-52. doi:10.1016/j.niox.2024.07.005

Pavelec, C. M., Young, A. P., Luviano, H. L., Orrell, E. E., Szagdaj, A., Poudel, N., . . . Leitinger, N. (2024). Cardiomyocyte PANX1 Controls Glycolysis and Neutrophil Recruitment in Hypertrophy. CIRCULATION RESEARCH, 135(4), 503-517. doi:10.1161/CIRCRESAHA.124.324650

Luse, M. A., Dunaway, L. S., Nyshadham, S., Carvalho, A., Sedovy, M. W., Ruddiman, C. A., . . . Isakson, B. E. (2024). Endothelial-adipocyte Cx43 mediated gap junctions can regulate adiposity.. Function (Oxford, England), zqae029. doi:10.1093/function/zqae029

Kharel, Y., Huang, T., Dunnavant, K., Foster, D., Souza, G., Nimchuk, K. E., . . . Lynch, K. R. (2024). Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target.. bioRxiv. doi:10.1101/2024.03.26.586765

Pavelec, C. M., Young, A. P., Luviano, H. L., Orrell, E. E., Szagdaj, A., Poudel, N., . . . Leitinger, N. (2024). Pannexin 1 Channels Control Cardiomyocyte Metabolism and Neutrophil Recruitment During Non-Ischemic Heart Failure.. bioRxiv. doi:10.1101/2023.12.29.573679

Dunaway, L. S., Loeb, S. A., Petrillo, S., Tolosano, E., & Isakson, B. E. (2024). Heme metabolism in nonerythroid cells.. The Journal of biological chemistry, 300(4), 107132. doi:10.1016/j.jbc.2024.107132

Wolpe, A. G., Luse, M. A., Baryiames, C., Schug, W. J., Wolpe, J. B., Johnstone, S. R., . . . Isakson, B. E. (2024). Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress. SCIENCE SIGNALING, 17(821). doi:10.1126/scisignal.adg2622

Dunaway, L. S., Luse, M. A., Nyshadham, S., Bulut, G., Alencar, G. F., Chavkin, N. W., . . . Isakson, B. E. (2024). Obesogenic diet disrupts tissue-specific mitochondrial gene signatures in the artery and capillary endothelium.. Physiological genomics, 56(2), 113-127. doi:10.1152/physiolgenomics.00109.2023

Sveeggen, T. M., Isakson, B. E., Straub, A. C., & Bagher, P. (2023). Bedding as a variable affecting fasting blood glucose and vascular physiology in mice. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 325(2), H338-H345. doi:10.1152/ajpheart.00168.2023

Luse, M. A., Jackson, M. G., Juskiewicz, Z. J., & Isakson, B. E. (2023). Physiological functions of caveolae in endothelium. CURRENT OPINION IN PHYSIOLOGY, 35. doi:10.1016/j.cophys.2023.100701

Ruddiman, C. A., Peckham, R., Luse, M. A., Chen, Y. -L., Kuppusamy, M., Corliss, B. A., . . . Isakson, B. E. (2023). Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1. JCI INSIGHT, 8(9). doi:10.1172/jci.insight.165715

Koval, M., Schug, W. J., & Isakson, B. E. (2023). Pharmacology of pannexin channels. CURRENT OPINION IN PHARMACOLOGY, 69. doi:10.1016/j.coph.2023.102359

Shah, S. A., Reagan, C. E., Bresticker, J. E., Wolpe, A. G., Good, M. E., Macal, E. H., . . . Epstein, F. H. (2023). Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition. JACC-BASIC TO TRANSLATIONAL SCIENCE, 8(5), 501-514. doi:10.1016/j.jacbts.2022.11.005

Ragland, T. J., Heiston, E. M., Ballantyne, A., Stewart, N. R., La Salvia, S., Musante, L., . . . Malin, S. K. (2023). Extracellular vesicles and insulin-mediated vascular function in metabolic syndrome. PHYSIOLOGICAL REPORTS, 11(1). doi:10.14814/phy2.15530

Chu, P. -L., Gigliotti, J. C., Cechova, S., Bodonyi-Kovacs, G., Wang, Y. T., Chen, L., . . . Le, T. H. (2023). Collectrin (Tmem27) deficiency in proximal tubules causes hypertension in mice and a TMEM27 variant associates with blood pressure in males in a Latino cohort. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 324(1), F30-F42. doi:10.1152/ajprenal.00176.2022

Dunaway, L. S., Billaud, M., Macal, E., Good, M. E., Medina, C. B., Lorenz, U., . . . Isakson, B. E. (2023). Amount of Pannexin 1 in Smooth Muscle Cells Regulates Sympathetic Nerve-Induced Vasoconstriction. HYPERTENSION, 80(2), 416-425. doi:10.1161/HYPERTENSIONAHA.122.20280

Luse, M. A., Kruger, N., Good, M. E., Biwer, L. A., Serbulea, V., Salamon, A., . . . Isakson, B. E. (2022). Smooth muscle cell FTO regulates contractile function. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 323(6), H1212-H1220. doi:10.1152/ajpheart.00427.2022

Keller, T. C. S., Lechauve, C., Keller, A. S., Broseghini-Filho, G. B., Butcher, J. T., Page, H. R. A., . . . Isakson, B. E. (2022). Endothelial alpha globin is a nitrite reductase. NATURE COMMUNICATIONS, 13(1). doi:10.1038/s41467-022-34154-3

Baldwin, S. N., Forrester, E. A., Homer, N. Z. M., Andrew, R., Barrese, V., Stott, J. B., . . . Greenwood, I. A. (2023). Marked oestrous cycle-dependent regulation of rat arterial K_V7.4 channels driven by GPER1. BRITISH JOURNAL OF PHARMACOLOGY, 180(2), 174-193. doi:10.1111/bph.15947

King, D. R., Sedovy, M. W., Eaton, X., Dunaway, L. S., Good, M. E., Isakson, B. E., & Johnstone, S. R. (2022). Cell-to-cell Communication in the Resistance Vasculature. COMPREHENSIVE PHYSIOLOGY, 12(4), 3833-3867. doi:10.1002/cphy.c210040

Granade, M. E., Hargett, S. R., Lank, D. S., Lemke, M. C., Luse, M. A., Isakson, B. E., . . . Harris, T. E. (2022). Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation. MOLECULAR METABOLISM, 63. doi:10.1016/j.molmet.2022.101543

Cortese-Krott, M. M., Suvorava, T., Leo, F., Heuser, S. K., LoBue, A., Li, J., . . . Kelm, M. (2022). Red blood cell eNOS is cardioprotective in acute myocardial infarction. REDOX BIOLOGY, 54. doi:10.1016/j.redox.2022.102370

Wolpe, A. G., Luse, M. A., Johnstone, S. R., Xue, J., Sabapathy, V., Wakefield, B., . . . Isakson, B. E. (2022). Endothelial Pannexin 3-B Cell Lymphoma-6 Interactions Protect Against Oxidative Stress. FASEB JOURNAL, 36. doi:10.1096/fasebj.2022.36.S1.R5405

Luse, M. A., Pavelic, C., Tessema, R., Cochran, J., Minshall, R. D., Leitinger, N., & Isakson, B. E. (2022). Genetic deletion of endothelial Caveolin-1 is protective against metabolic disease.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36 Suppl 1. doi:10.1096/fasebj.2022.36.s1.r5416

Wenceslau, C. F., McCarthy, C. G., Earley, S., England, S. K., Filosa, J. A., Goulopoulou, S., . . . Webb, R. C. (2022). Reply to Boedtkjer and Aalkjaer. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 322(4), H687-H688. doi:10.1152/ajpheart.00117.2022

Wenceslau, C. F., McCarthy, C. G., Earley, S., England, S. K., Filosa, J. A., Goulopoulou, S., . . . Webb, R. C. (2022). Reply to De Mey et al.. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 322(4), H683-H684. doi:10.1152/ajpheart.00086.2022

Filiberto, A. C., Spinosa, M. D., Elder, C. T., Su, G., Leroy, V., Ladd, Z., . . . Sharma, A. K. (2022). Endothelial pannexin-1 channels modulate macrophage and smooth muscle cell activation in abdominal aortic aneurysm formation. NATURE COMMUNICATIONS, 13(1). doi:10.1038/s41467-022-29233-4

Molina, S. A., Maier-Begandt, D., Isakson, B. E., & Koval, M. (2022). Electrophysiological Measurements of Isolated Blood Vessels. BIO-PROTOCOL, 12(6). doi:10.21769/BioProtoc.4359

Kiger, L., Keith, J., Freiwan, A., Fernandez, A. G., Tillman, H., Isakson, B. E., . . . Lechauve, C. (2022). Redox-Regulation of α-Globin in Vascular Physiology. ANTIOXIDANTS, 11(1). doi:10.3390/antiox11010159

Grimmer, B., Krauszman, A., Hu, X., Kabir, G., Connelly, K. A., Li, M., . . . Kuebler, W. M. (2022). Pannexin 1: a novel regulator of acute hypoxic pulmonary vasoconstriction. CARDIOVASCULAR RESEARCH, 118(11), 2535-2547. doi:10.1093/cvr/cvab326

King, D. R., Sedovy, M. W., Leng, X., Xue, J., Lamouille, S., Koval, M., . . . Johnstone, S. R. (2021). Mechanisms of Connexin Regulating Peptides. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(19). doi:10.3390/ijms221910186

Daneva, Z., Ottolini, M., Chen, Y. L., Klimentova, E., Kuppusamy, M., Shah, S. A., . . . Sonkusare, S. K. (2021). Endothelial pannexin 1-TRPV4 channel signaling lowers pulmonary arterial pressure in mice. ELIFE, 10. doi:10.7554/eLife.67777

Keller, T. C. S., Lechauve, C., Keller, A. S., Brooks, S., Weiss, M. J., Columbus, L., . . . Isakson, B. E. (2022). THE ROLE OF GLOBINS IN CARDIOVASCULAR PHYSIOLOGY. PHYSIOLOGICAL REVIEWS, 102(2), 859-892. doi:10.1152/physrev.00037.2020

Bisht, K., Okojie, K. A., Sharma, K., Lentferink, D. H., Sun, Y. -Y., Chen, H. -R., . . . Eyo, U. B. (2021). Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-25590-8

Koval, M., Cwiek, A., Carr, T., Good, M. E., Lohman, A. W., & Isakson, B. E. (2021). Pannexin 1 as a driver of inflammation and ischemia-reperfusion injury. PURINERGIC SIGNALLING, 17(4), 521-531. doi:10.1007/s11302-021-09804-8

Leo, F., Suvorava, T., Heuser, S. K., Li, J., LoBue, A., Barbarino, F., . . . Cortese-Krott, M. M. (2021). Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure. CIRCULATION, 144(11), 870-889. doi:10.1161/CIRCULATIONAHA.120.049606

Wenceslau, C. F., McCarthy, C. G., Earley, S., England, S. K., Filosa, J. A., Goulopoulou, S., . . . Webb, R. C. (2021). Guidelines for the measurement of vascular function and structure in isolated arteries and veins. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 321(1), H77-H111. doi:10.1152/ajpheart.01021.2020

Daneva, Z., Marziano, C., Ottolini, M., Chen, Y. -L., Baker, T. M., Kuppusamy, M., . . . Sonkusare, S. K. (2021). Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(17). doi:10.1073/pnas.2023130118

Maier-Begandt, D., Comstra, H. S., Molina, S. A., Krueger, N., Ruddiman, C. A., Chen, Y. -L., . . . Isakson, B. E. (2021). A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. SCIENCE SIGNALING, 14(672). doi:10.1126/scisignal.aba2940

Good, M. E., Young, A. P., Wolpe, A. G., Ma, M., Hall, P. J., Duffy, C. K., . . . Isakson, B. E. (2021). Endothelial Pannexin 1 Regulates Cardiac Response to Myocardial Infarction. CIRCULATION RESEARCH, 128(8), 1211-1213. doi:10.1161/CIRCRESAHA.120.317272

Thakore, P., Alvarado, M. G., Ali, S., Mughal, A., Pires, P. W., Yamasaki, E., . . . Earley, S. (2021). Brain endothelial cell TRPA1 channels initiate neurovascular coupling. ELIFE, 10. doi:10.7554/eLife.63040

Wolpe, A. G., Ruddiman, C. A., Hall, P. J., & Isakson, B. E. (2021). Polarized Proteins in Endothelium and Their Contribution to Function. JOURNAL OF VASCULAR RESEARCH, 58(2), 65-91. doi:10.1159/000512618

Bories, G. F. P., Yeudall, S., Serbulea, V., Fox, T. E., Isakson, B. E., & Leitinger, N. (2020). Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway. BLOOD, 136(13), 1535-1548. doi:10.1182/blood.2020004964

Wischmann, P., Kuhn, V., Suvorava, T., Muessig, J. M., Fischer, J. W., Isakson, B. E., . . . Kelm, M. (2020). Anaemia is associated with severe RBC dysfunction and a reduced circulating NO pool: vascular and cardiac eNOS are crucial for the adaptation to anaemia. BASIC RESEARCH IN CARDIOLOGY, 115(4). doi:10.1007/s00395-020-0799-x

DeLalio, L. J., Masati, E., Mendu, S., Ruddiman, C. A., Yang, Y., Johnstone, S. R., . . . Isakson, B. E. (2020). Pannexin 1 channels in renin-expressing cells influence renin secretion and blood pressure homeostasis. KIDNEY INTERNATIONAL, 98(3), 630-644. doi:10.1016/j.kint.2020.04.041

Yang, Y., Delalio, L. J., Best, A. K., Macal, E., Milstein, J., Donnelly, I., . . . Johnstone, S. R. (2020). Endothelial Pannexin 1 Channels Control Inflammation by Regulating Intracellular Calcium. JOURNAL OF IMMUNOLOGY, 204(11), 2995-3007. doi:10.4049/jimmunol.1901089

Garcia, V., Park, E. J., Siragusa, M., Frohlich, F., Haque, M. M., Pascale, J. V., . . . Sessa, W. C. (2020). Unbiased proteomics identifies plasminogen activator inhibitor-1 as a negative regulator of endothelial nitric oxide synthase. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(17), 9497-9507. doi:10.1073/pnas.1918761117

Biwer, L. A., Askew-Page, H. R., Hong, K., Milstein, J., Johnstone, S. R., Macal, E., . . . Isakson, B. E. (2020). Endothelial calreticulin deletion impairs endothelial function in aged mice. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 318(5), H1041-H1048. doi:10.1152/ajpheart.00586.2019

Leo, F., Krenz, T., Wolff, G., Weidenbach, M., Heiss, C., Kelm, M., . . . Cortese-Krott, M. M. (2020). Assessment of tissue perfusion and vascular function in mice by scanning laser Doppler perfusion imaging. BIOCHEMICAL PHARMACOLOGY, 176. doi:10.1016/j.bcp.2020.113893

Ottolini, M., Hong, K., Cope, E. L., Daneva, Z., DeLalio, L. J., Sokolowski, J. D., . . . Sonkusare, S. K. (2020). Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity. CIRCULATION, 141(16), 1318-1333. doi:10.1161/CIRCULATIONAHA.119.043385

Leo, F., Hutzler, B., Ruddiman, C. A., Isakson, B. E., & Cortese-Krott, M. M. (2020). Cellular microdomains for nitric oxide signaling in endothelium and red blood cells. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 96, 44-53. doi:10.1016/j.niox.2020.01.002

Luse, M. A., Heiston, E. M., Malin, S. K., & Isakson, B. E. (2020). Cellular and Functional Effects of Insulin Based Therapies and Exercise on Endothelium. CURRENT PHARMACEUTICAL DESIGN, 26(30), 3760-3767. doi:10.2174/1381612826666200721002735

McCallinhart, P. E., Biwer, L. A., Clark, O. E., Isakson, B. E., Lilly, B., & Trask, A. J. (2020). Myoendothelial Junctions of Mature Coronary Vessels Express Notch Signaling Proteins. FRONTIERS IN PHYSIOLOGY, 11. doi:10.3389/fphys.2020.00029

Jankowski, J., Perry, H. M., Medina, C. B., Huang, L., Yao, J., Bajwa, A., . . . Okusa, M. D. (2020). Epithelial and endothelial pannexin1 channels mediate AKI (vol 29, pg 1887, 2018). JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 31(1), 231. doi:10.1681/ASN.2019111140

Kruger, N., Biwer, L. A., Good, M. E., Ruddiman, C. A., Wolpe, A. G., DeLalio, L. J., . . . Isakson, B. E. (2020). Loss of Endothelial FTO Antagonizes Obesity-Induced Metabolic and Vascular Dysfunction. CIRCULATION RESEARCH, 126(2), 232-242. doi:10.1161/CIRCRESAHA.119.315531

Good, M. E., Musante, L., La Salvia, S., Howell, N. L., Carey, R. M., Le, T. H., . . . Erdbruegger, U. (2020). Circulating Extracellular Vesicles in Normotension Restrain Vasodilation in Resistance Arteries. HYPERTENSION, 75(1), 218-228. doi:10.1161/HYPERTENSIONAHA.119.13363

Rival, C. M., Xu, W., Shankman, L. S., Morioka, S., Arandjelovic, S., Lee, C. S., . . . Ravichandran, K. S. (2019). Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-12406-z

Shu, X., Ruddiman, C. A., Keller, T. C. S., Keller, A. S., Yang, Y., Good, M. E., . . . Isakson, B. E. (2019). Heterocellular Contact Can Dictate Arterial Function. CIRCULATION RESEARCH, 124(10), 1473-1481. doi:10.1161/CIRCRESAHA.118.313926

Li, J., Cechova, S., Wang, L., Isakson, B. E., Le, T. H., & Shi, W. (2019). Loss of reticulocalbin 2 lowers blood pressure and restrains ANG II-induced hypertension in vivo. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 316(6), F1141-F1150. doi:10.1152/ajprenal.00567.2018

DeLalio, L. J., Billaud, M., Ruddiman, C. A., Johnstone, S. R., Butcher, J. T., Wolpe, A. G., . . . Isakson, B. E. (2019). Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane. JOURNAL OF BIOLOGICAL CHEMISTRY, 294(17), 6940-6956. doi:10.1074/jbc.RA118.006982

Novielli-Kuntz, N. M., Jelen, M., Barr, K., DeLalio, L. J., Feng, Q., Isakson, B. E., . . . Laird, D. W. (2019). Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice. BIOSCIENCE REPORTS, 39. doi:10.1042/BSR20182350

Corliss, B. A., Delalio, L. J., Keller, T. C. S., Keller, A. S., Keller, D. A., Corliss, B. H., . . . Isakson, B. E. (2019). Vascular Expression of Hemoglobin Alpha in Antarctic Icefish Supports Iron Limitation as Novel Evolutionary Driver. FRONTIERS IN PHYSIOLOGY, 10. doi:10.3389/fphys.2019.01389

Artamonov, M. V., Sonkusare, S. K., Good, M. E., Momotani, K., Eto, M., Isakson, B. E., . . . Somlyo, A. V. (2018). RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na⁺/H⁺ exchanger. SCIENCE SIGNALING, 11(554). doi:10.1126/scisignal.aar3924

Suarez-Martinez, A. D., Peirce, S. M., Isakson, B. E., Nice, M., Wang, J., Lounsbury, K. M., . . . Murfee, W. L. (2018). Induction of microvascular network growth in the mouse mesentery. MICROCIRCULATION, 25(8). doi:10.1111/micc.12502

Lechauve, C., Butcher, J. T., Freiwan, A., Biwer, L. A., Keith, J. M., Good, M. E., . . . Weiss, M. J. (2018). Endothelial cell α-globin and its molecular chaperone α-hemoglobin-stabilizing protein regulate arteriolar contractility. JOURNAL OF CLINICAL INVESTIGATION, 128(11), 5073-5082. doi:10.1172/JCI99933

Good, M. E., & Isakson, B. E. (2018). "Yin and Yang" for Notch signaling in the mature vasculature. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 315(6), H1789-H1790. doi:10.1152/ajpheart.00626.2018

Brown, I. A. M., Diederich, L., Good, M. E., DeLalio, L. J., Murphy, S. A., Cortese-Krott, M. M., . . . Isakson, B. E. (2018). Vascular Smooth Muscle Remodeling in Conductive and Resistance Arteries in Hypertension. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 38(9), 1969-1985. doi:10.1161/ATVBAHA.118.311229

DeLalio, L. J., Keller, A. S., Chen, J., Boyce, A. K. J., Artamonov, M. V., Askew-Page, H. R., . . . Isakson, B. E. (2018). Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 38(9), 2065-2078. doi:10.1161/ATVBAHA.118.311290

Molica, F., Figueroa, X. F., Kwak, B. R., Isakson, B. E., & Gibbins, J. M. (2018). Connexins and Pannexins in Vascular Function and Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(6). doi:10.3390/ijms19061663

Jankowski, J., Perry, H. M., Medina, C. B., Huang, L., Yao, J., Bajwa, A., . . . Okusa, M. D. (2018). Epithelial and Endothelial Pannexin1 Channels Mediate AKI. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 29(7), 1887-1899. doi:10.1681/ASN.2017121306

Good, M. E., Chiu, Y. -H., Poon, I. K. H., Jaffe, I. Z., Bayliss, D. A., Isakson, B. E., & Ravichandran, K. S. (2018). Response by Good et al to Letter Regarding Article, "Pannexin-1 Channels as an Unexpected New Target of the Antihypertensive Drug Spironolactone". CIRCULATION RESEARCH, 122(11), E88-E89. doi:10.1161/CIRCRESAHA.118.313080

Sharma, A. K., Charles, E. J., Zhao, Y., Narahari, A. K., Baderdinni, P. K., Good, M. E., . . . Laubach, V. E. (2018). Pannexin-1 channels on endothelial cells mediate vascular inflammation during lung ischemia-reperfusion injury. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 315(2), L301-L312. doi:10.1152/ajplung.00004.2018

Haskins, R. M., Nguyen, A. T., Alencar, G. F., Billaud, M., Kelly-Goss, M. R., Good, M. E., . . . Owens, G. K. (2018). Klf4 has an unexpected protective role in perivascular cells within the microvasculature. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 315(2), H402-H414. doi:10.1152/ajpheart.00084.2018

Johnstone, S. R., & Isakson, B. E. (2018). "Gaps' in targeted ischaemic injury therapies in ST-elevation myocardial infarction. HEART, 104(19), 1557-1558. doi:10.1136/heartjnl-2018-313084

Good, M. E., Eucker, S. A., Li, J., Bacon, H. M., Lang, S. M., Butcher, J. T., . . . Isakson, B. E. (2018). Endothelial cell Pannexin1 modulates severity of ischemic stroke by regulating cerebral inflammation and myogenic tone. JCI INSIGHT, 3(6). doi:10.1172/jci.insight.96272

Hong, K., Cope, E. L., DeLalio, L. J., Marziano, C., Isakson, B. E., & Sonkusare, S. K. (2018). TRPV4 (Transient Receptor Potential Vanilloid 4) Channel-Dependent Negative Feedback Mechanism Regulates G_q Protein-Coupled Receptor-Induced Vasoconstriction. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 38(3), 542-554. doi:10.1161/ATVBAHA.117.310038

Keller, A. S., Keller, T. C. S., DeLalio, L. J., Shahab, G., Yang, Y., Murphy, S. A., . . . Isakson, B. E. (2018). Replacement Therapies in Metabolic Disease. CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 19(5), 382-399. doi:10.2174/1389201019666180619151413

Diederich, L., Suvorava, T., Sansone, R., Keller, T. C. S., Barbarino, F., Sutton, T. R., . . . Cortese-Krott, M. M. (2018). On the Effects of Reactive Oxygen Species and Nitric Oxide on Red Blood Cell Deformability. FRONTIERS IN PHYSIOLOGY, 9. doi:10.3389/fphys.2018.00332

Nyberg, M., Piil, P., Kiehn, O. T., Maagaard, C., Jorgensen, T. S., Egelund, J., . . . Hellsten, Y. (2018). Probenecid Inhibits -Adrenergic Receptor-Mediated Vasoconstriction in the Human Leg Vasculature. HYPERTENSION, 71(1), 151-159. doi:10.1161/HYPERTENSIONAHA.117.10251

Marziano, C., Hong, K., Cope, E. L., Kotlikoff, M. I., Isakson, B. E., & Sonkusare, S. K. (2017). Nitric Oxide-Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 6(12). doi:10.1161/JAHA.117.007157

Good, M. E., Chiu, Y. -H., Poon, I. K. H., Medina, C. B., Butcher, J. T., Mendu, S. K., . . . Ravichandran, K. S. (2018). Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone. CIRCULATION RESEARCH, 122(4), 606-615. doi:10.1161/CIRCRESAHA.117.312380

Biwer, L. A., Good, M. E., Hong, K., Patel, R. K., Agrawal, N., Looft-Wilson, R., . . . Isakson, B. E. (2018). Non-Endoplasmic Reticulum-Based Calr (Calreticulin) Can Coordinate Heterocellular Calcium Signaling and Vascular Function. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 38(1), 120-130. doi:10.1161/ATVBAHA.117.309886

Nyberg, M., Piil, P., Kiehn, O. T., Maagaard, C., Jørgensen, T. S., Egelund, J., . . . Hellsten, Y. (2018). Probenecid Inhibits α-Adrenergic Receptor-Mediated Vasoconstriction in the Human Leg Vasculature.. Hypertension (Dallas, Tex. : 1979), 71(1), 151-159. doi:10.1161/hypertensionaha.117.10251

Biwer, L. A., Lechauve, C., Vanhoose, S., Weiss, M. J., & Isakson, B. E. (2017). A Cell Culture Model of Resistance Arteries. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (127). doi:10.3791/55992

Keller, A. S., Diederich, L., Panknin, C., DeLalio, L. J., Drake, J. C., Sherman, R., . . . Isakson, B. E. (2017). Possible roles for ATP release from RBCs exclude the cAMP-mediated Panx1 pathway. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 313(6), C593-C603. doi:10.1152/ajpcell.00178.2017

DeLalio, L. J., & Isakson, B. E. (2017). ZP1609/danegaptide and mitochondrial connexin hemichannels: a harbinger for peptide drug design. BRITISH JOURNAL OF PHARMACOLOGY, 174(15), 2606-2607. doi:10.1111/bph.13891

Keller, A. S., & Isakson, B. E. (2017). The Evolving Role of Diverse Gaseous Transmitters Mediating Heterocellular Communication Within the Vasculature. ANTIOXIDANTS & REDOX SIGNALING, 26(16), 881-885. doi:10.1089/ars.2017.7059

Durgin, B. G., Cherepanova, O. A., Gomez, D., Karaoli, T., Alencar, G. F., Butcher, J. T., . . . Connelly, J. J. (2017). Smooth muscle cell-specific deletion of Col15a1 unexpectedly leads to impaired development of advanced atherosclerotic lesions. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 312(5), H943-H958. doi:10.1152/ajpheart.00029.2017

Kuhn, V., Diederich, L., Keller, T. C. S., Kramer, C. M., Lueckstaedt, W., Panknin, C., . . . Cortese-Krott, M. M. (2017). Red Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia. ANTIOXIDANTS & REDOX SIGNALING, 26(13), 718-742. doi:10.1089/ars.2016.6954

Begandt, D., Good, M. E., Keller, A. S., DeLalio, L. J., Rowley, C., Isakson, B. E., & Figueroa, X. F. (2017). Pannexin channel and connexin hemichannel expression in vascular function and inflammation. BMC CELL BIOLOGY, 18. doi:10.1186/s12860-016-0119-3

Isakson, B. (2017). A review of the current state of pannexin channels as they relate to the blood vessel wall. Journal of Medical Sciences, 37(5), 179. doi:10.4103/jmedsci.jmedsci_43_17

Keller, T. C. S., Butcher, J. T., Broseghini-Filho, G. B., Marziano, C., DeLalio, L. J., Rogers, S., . . . Isakson, B. E. (2016). Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbX). HYPERTENSION, 68(6), 1494-1503. doi:10.1161/HYPERTENSIONAHA.116.08171

Liu, S., DeLalio, L. J., Isakson, B. E., & Wang, T. T. (2016). AXL-Mediated Productive Infection of Human Endothelial Cells by Zika Virus. CIRCULATION RESEARCH, 119(11), 1183-+. doi:10.1161/CIRCRESAHA.116.309866

Kauffenstein, G., Tamareille, S., Prunier, F., Roy, C., Ayer, A., Toutain, B., . . . Henrion, D. (2016). Central Role of P2Y₆ UDP Receptor in Arteriolar Myogenic Tone. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 36(8), 1598-1606. doi:10.1161/ATVBAHA.116.307739

Biwer, L. A., Taddeo, E. P., Kenwood, B. M., Hoehn, K. L., Straub, A. C., & Isakson, B. E. (2016). Two functionally distinct pools of eNOS in endothelium are facilitated by myoendothelial junction lipid composition. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1861(7), 671-679. doi:10.1016/j.bbalip.2016.04.014

Biwer, L. A., & Isakson, B. E. (2017). Endoplasmic reticulum-mediated signalling in cellular microdomains. ACTA PHYSIOLOGICA, 219(1), 162-175. doi:10.1111/apha.12675

Ivanov, S., Scallan, J. P., Kim, K. -W., Werth, K., Johnson, M. W., Saunders, B. T., . . . Randolph, G. J. (2016). CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability. JOURNAL OF CLINICAL INVESTIGATION, 126(4), 1581-1591. doi:10.1172/JCI84518

Shankman, L. S., Gomez, D., Cherepanova, O. A., Salmon, M., Alencar, G. F., Haskins, R. M., . . . Owens, G. K. (2016). Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.. Nature medicine, 22(2), 217. doi:10.1038/nm0216-217a

Shankman, L. S., Gomez, D., Cherepanova, O. A., Salmon, M., Alencar, G. F., Haskins, R. M., . . . Owens, G. K. (2016). KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis (vol 21, pg 628, 2015). NATURE MEDICINE, 22(2), 217. doi:10.1038/nm0216-217a

Good, M. E., Begandt, D., DeLalio, L. J., Johnstone, S. R., & Isakson, B. E. (2016). Small Interfering RNA-Mediated Connexin Gene Knockdown in Vascular Endothelial and Smooth Muscle Cells. GAP JUNCTION PROTOCOLS, 1437, 71-82. doi:10.1007/978-1-4939-3664-9_5

Shu, X., Keller, T. C. S., Begandt, D., Butcher, J. T., Biwer, L., Keller, A. S., . . . Isakson, B. E. (2015). Endothelial nitric oxide synthase in the microcirculation. CELLULAR AND MOLECULAR LIFE SCIENCES, 72(23), 4561-4575. doi:10.1007/s00018-015-2021-0

Chen, C. -H., Mayo, J. N., Gourdie, R. G., Johnstone, S. R., Isakson, B. E., & Bearden, S. E. (2015). The connexin 43/ZO-1 complex regulates cerebral endothelial F-actin architecture and migration. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 309(9), C600-C607. doi:10.1152/ajpcell.00155.2015

Lohman, A. W., Leskov, I. L., Butcher, J. T., Johnstone, S. R., Stokes, T. A., Begandt, D., . . . Isakson, B. E. (2015). Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation. NATURE COMMUNICATIONS, 6. doi:10.1038/ncomms8965

Adamson, S. E., Meher, A. K., Chiu, Y. -H., Sandilos, J. K., Oberholtzer, N. P., Walker, N. N., . . . Leitinger, N. (2015). Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes. MOLECULAR METABOLISM, 4(9), 610-618. doi:10.1016/j.molmet.2015.06.009

Good, M. E., Begandt, D., DeLalio, L. J., Keller, A. S., Billaud, M., & Isakson, B. E. (2015). Emerging concepts regarding pannexin 1 in the vasculature. BIOCHEMICAL SOCIETY TRANSACTIONS, 43, 495-501. doi:10.1042/BST20150045

Shankman, L. S., Gomez, D., Cherepanova, O. A., Salmon, M., Alencar, G. F., Haskins, R. M., . . . Owens, G. K. (2015). KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. NATURE MEDICINE, 21(6), 628-637. doi:10.1038/nm.3866

Billaud, M., Chiu, Y. -H., Lohman, A. W., Parpaite, T., Butcher, J. T., Mutchler, S. M., . . . Isakson, B. E. (2015). A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells. SCIENCE SIGNALING, 8(364). doi:10.1126/scisignal.2005824

Butcher, J., DeLalio, L., Biwer, L., Lang, S., Weaver, R., Best-Campbell, A., . . . Isakson, B. (2015). Endothelial Cell Hbα Can Regulate Blood Pressure. FASEB JOURNAL, 29. Retrieved from https://www.webofscience.com/

Kavoussi, P. K., Heberlein, K., Straub, A. C., Lowe, G. J., Oliver, J. L., Smith, R. P., . . . Lysiak, J. J. (2015). Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice. ANDROLOGIA, 47(10), 1147-1152. doi:10.1111/and.12395

Straub, A. C., Butcher, J. T., Billaud, M., Mutchler, S. M., Artamonov, M. V., Nguyen, A. T., . . . Isakson, B. E. (2014). Hemoglobin α/eNOS Coupling at Myoendothelial Junctions Is Required for Nitric Oxide Scavenging During Vasoconstriction. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 34(12), 2594-2600. doi:10.1161/ATVBAHA.114.303974

Straub, A. C., Zeigler, A. C., & Isakson, B. E. (2014). The Myoendothelial Junction: Connections That Deliver the Message. PHYSIOLOGY, 29(4), 242-249. doi:10.1152/physiol.00042.2013

Butcher, J. T., Johnson, T., Beers, J., Columbus, L., & Isakson, B. E. (2014). Hemoglobin α in the blood vessel wall. FREE RADICAL BIOLOGY AND MEDICINE, 73, 136-142. doi:10.1016/j.freeradbiomed.2014.04.019

Koval, M., Isakson, B. E., & Gourdie, R. G. (2014). Connexins, pannexins and innexins: Protein cousins with overlapping functions. FEBS LETTERS, 588(8), 1185. doi:10.1016/j.febslet.2014.03.001

Lohman, A. W., & Isakson, B. E. (2014). Differentiating connexin hemichannels and pannexin channels in cellular ATP release. FEBS LETTERS, 588(8), 1379-1388. doi:10.1016/j.febslet.2014.02.004

Isakson, B. E. (2014). Secreting von Willebrand factor in a Gα-SNAP. BLOOD, 123(3), 312-313. doi:10.1182/blood-2013-10-531913

Butcher, J. T., DeLalio, L. J., Biwer, L. A., Weaver, R. B., & Isakson, B. E. (2014). Endothelial Hemoglobin Alpha by the HBA1 Gene Is Crucial to Release of NO-Derived Metabolites into Tissue and Blood. FREE RADICAL BIOLOGY AND MEDICINE, 76, S42. doi:10.1016/j.freeradbiomed.2014.10.390

Kauffenstein, G., Grimaud, L., Ayer, A., Toutain, B., Loufrani, L., Billaud, M., . . . Henrion, D. (2014). Signaling by extracellular nucleotides in resistance arteries-focus on myogenic tone. PURINERGIC SIGNALLING, 10(4), 798-799. Retrieved from https://www.webofscience.com/

Isakson, B. E. (2014). Pannexin 1 channels on smooth muscle cell regulates α1-adrenergic vasoconstriction and blood pressure. PURINERGIC SIGNALLING, 10(4), 671. Retrieved from https://www.webofscience.com/

Lohman, A., & Isakson, B. (2014). Pannexin 1-dependent ATP release from venous endothelium promotes acute vascular inflammation. FASEB JOURNAL, 28(1). Retrieved from https://www.webofscience.com/

Biwer, L., Straub, A., & Isakson, B. (2014). Subcellular enrichment of calreticulin at myoendothelial junctions. FASEB JOURNAL, 28(1). Retrieved from https://www.webofscience.com/

Straub, A., Anh, N., Mutchler, S., & Isakson, B. (2014). Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 42, 141. doi:10.1016/j.niox.2014.09.126

Penuela, S., Lohman, A. W., Lai, W., Gyenis, L., Litchfield, D. W., Isakson, B. E., & Laird, D. W. (2014). Diverse post-translational modifications of the pannexin family of channel-forming proteins. CHANNELS, 8(2), 124-130. doi:10.4161/chan.27422

Billaud, M., Lohman, A. W., Johnstone, S. R., Biwer, L. A., Mutchler, S., & Isakson, B. E. (2014). Regulation of Cellular Communication by Signaling Microdomains in the Blood Vessel Wall. PHARMACOLOGICAL REVIEWS, 66(2), 513-569. doi:10.1124/pr.112.007351

Isakson, B. E., & Thompson, R. J. (2014). Pannexin-1 as a potentiator of ligand-gated receptor signaling. CHANNELS, 8(2), 118-123. doi:10.4161/chan.27978

Adhikari, N., Billaud, M., Carlson, M., Lake, S. P., Montaniel, K. R. C., Staggs, R., . . . Hall, J. L. (2014). Vascular biomechanical properties in mice with smooth muscle specific deletion of Ndst1. MOLECULAR AND CELLULAR BIOCHEMISTRY, 385(1-2), 225-238. doi:10.1007/s11010-013-1831-3

Cechova, S., Zeng, Q., Billaud, M., Mutchler, S., Rudy, C. K., Straub, A. C., . . . Le, T. H. (2013). Loss of Collectrin, an Angiotensin-Converting Enzyme 2 Homolog, Uncouples Endothelial Nitric Oxide Synthase and Causes Hypertension and Vascular Dysfunction. CIRCULATION, 128(16), 1770-1780. doi:10.1161/CIRCULATIONAHA.113.003301

Isakson, B. (2013). REGULATION OF NO BY HEMOGLOBIN IN THE ENDOTHELIUM. FREE RADICAL BIOLOGY AND MEDICINE, 65, S8. doi:10.1016/j.freeradbiomed.2013.10.404

Straub, A. C., Lohman, A. W., Billaud, M., Johnstone, S. R., Dwyer, S. T., Lee, M. Y., . . . Isakson, B. E. (2012). Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. NATURE, 491(7424), 473-477. doi:10.1038/nature11626

Wang, L., Yin, J., Nickles, H. T., Ranke, H., Tabuchi, A., Hoffmann, J., . . . Kuebler, W. M. (2012). Hypoxic pulmonary vasoconstriction requires connexin 40-mediated endothelial signal conduction. JOURNAL OF CLINICAL INVESTIGATION, 122(11), 4218-4230. doi:10.1172/JCI59176

Lohman, A. W., Weaver, J. L., Billaud, M., Sandilos, J. K., Griffiths, R., Straub, A. C., . . . Isakson, B. E. (2012). S-Nitrosylation Inhibits Pannexin 1 Channel Function. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(47). doi:10.1074/jbc.M112.397976

Kauffenstein, G., Ayer, A., Toutain, B., Grimaud, L., Billaud, M., Isakson, B., . . . Henrion, D. (2012). 767 SIGNALING BY EXTRACELLULAR NUCLEOTIDES IN THE VASCULATURE – FOCUS ON MYOGENIC TONE. Journal of Hypertension, 30(Supplement 1), e221. doi:10.1097/01.hjh.0000420734.45312.8b

Lohman, A. W., Billaud, M., & Isakson, B. E. (2012). Mechanisms of ATP release and signalling in the blood vessel wall. CARDIOVASCULAR RESEARCH, 95(3), 269-280. doi:10.1093/cvr/cvs187

Johnstone, S. R., Billaud, M., Lohman, A. W., Taddeo, E. P., & Isakson, B. E. (2012). Posttranslational Modifications in Connexins and Pannexins. JOURNAL OF MEMBRANE BIOLOGY, 245(5-6), 319-332. doi:10.1007/s00232-012-9453-3

Johnstone, S. R., Kroncke, B. M., Straub, A. C., Best, A. K., Dunn, C. A., Mitchell, L. A., . . . Isakson, B. E. (2012). MAPK Phosphorylation of Connexin 43 Promotes Binding of Cyclin E and Smooth Muscle Cell Proliferation. CIRCULATION RESEARCH, 111(2), 201-U205. doi:10.1161/CIRCRESAHA.112.272302

Montaniel, K. R. C., Billaud, M., Graham, C., Kim, S. K., Carlson, M., Zeng, W., . . . Adhikari, N. (2012). Smooth Muscle Specific Deletion of Ndst1 Leads to Decreased Vessel Luminal Area and No Change in Blood Pressure in Conscious Mice. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 5(3), 274-279. doi:10.1007/s12265-012-9369-4

Billaud, M., Lohman, A. W., Straub, A. C., Parpaite, T., Johnstone, S. R., & Isakson, B. E. (2012). Characterization of the Thoracodorsal Artery: Morphology and Reactivity. MICROCIRCULATION, 19(4), 360-372. doi:10.1111/j.1549-8719.2012.00172.x

Billaud, M., Sandilos, J. K., & Isakson, B. E. (2012). Pannexin 1 in the Regulation of Vascular Tone. TRENDS IN CARDIOVASCULAR MEDICINE, 22(3), 68-72. doi:10.1016/j.tcm.2012.06.014

Billaud, M., Johnstone, S. R., & Isakson, B. E. (2012). Loss of Compliance in Small Arteries, but Not in Conduit Arteries, After 6 Weeks Exposure to High Fat Diet. JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 5(3), 256-263. doi:10.1007/s12265-012-9354-y

Heberlein, K. R., Han, J., Straub, A. C., Best, A. K., Kaun, C., Wojta, J., & Isakson, B. E. (2012). A Novel mRNA Binding Protein Complex Promotes Localized Plasminogen Activator Inhibitor-1 Accumulation at the Myoendothelial Junction. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(5), 1271-+. doi:10.1161/ATVBAHA.112.246371

Straub, A., Dwyer, S., Gaston, B., & Isakson, B. (2012). Endothelial cell expression of hemoglobin a regulates nitric oxide signaling. NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 27, S13. doi:10.1016/j.niox.2012.04.048

Montaniel, K. R. C., Adhikari, N., Lake, S., Billaud, M., Carlson, M., Isakson, B. E., . . . Hall, J. L. (2012). Smooth Muscle Specific Deletion of N-deacetylase-sulfotransferase1 (Ndst1) Results in Altered Arterial Elasticity. CIRCULATION, 126(21). Retrieved from https://www.webofscience.com/

Billaud, M., Lohman, A. W., Chiu, Y. -H., Sandilos, J. K., Bayliss, D. A., & Isakson, B. E. (2012). Exclusive interaction between α1D-adrenergic receptor and pannexin 1 can mediate vasoconstriction. FASEB JOURNAL, 26. Retrieved from https://www.webofscience.com/

Lohman, A. W., Weaver, J. L., Billaud, M., Bayliss, D. A., & Isakson, B. E. (2012). Complex interplay between Pannexin 1 cysteine residues and channel regulation. FASEB JOURNAL, 26. Retrieved from https://www.webofscience.com/

Straub, A., Lohman, A., Billaud, M., Dwyer, S., Best, A., Gaston, B., & Isakson, B. (2012). Cytochrome B 5 reductase 3 regulates nitric oxide signaling at the myoendothelial by controlling hemoglobin redox cycling. FASEB JOURNAL, 26. Retrieved from https://www.webofscience.com/

Johnstone, S. R., Kroncke, B. M., Straub, A. C., Best, A. K., Dunn, C. A., Koval, M., . . . Isakson, B. E. (2012). MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. FASEB JOURNAL, 26. Retrieved from https://www.webofscience.com/

Straub, A., Lohman, A., Billaud, M., Johnstone, S., Dwyer, S., Lee, M., . . . Isakson, B. (2012). Hemoglobin expression at the myoendothelial junction regulates nitric oxide scavenging and vasomotor tone. FASEB JOURNAL, 26. Retrieved from https://www.webofscience.com/

Lohman, A. W., Billaud, M., Straub, A. C., Best, A. K., Lee, M., Barr, K., . . . Isakson, B. E. (2012). Expression of pannexin isoforms in the murine arterial network. FASEB JOURNAL, 26. Retrieved from https://www.webofscience.com/

Lowe, G., Kavoussi, P., Straub, A., Steers, W., Costabile, R., Isakson, B., & Lysiak, J. (2012). MYOENDOTHELIAL JUNCTIONS IN THE CORPUS CAVERNOSUM ARE LOST AFTER CAVERNOUS NERVE INJURY. JOURNAL OF SEXUAL MEDICINE, 9, 11. Retrieved from https://www.webofscience.com/

Lohman, A. W., Billaud, M., Straub, A. C., Johnstone, S. R., Best, A. K., Lee, M., . . . Isakson, B. E. (2012). Expression of Pannexin Isoforms in the Systemic Murine Arterial Network. JOURNAL OF VASCULAR RESEARCH, 49(5), 405-416. doi:10.1159/000338758

Looft-Wilson, R. C., Billaud, M., Johnstone, S. R., Straub, A. C., & Isakson, B. E. (2012). Interaction between nitric oxide signaling and gap junctions: Effects on vascular function. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1818(8), 1895-1902. doi:10.1016/j.bbamem.2011.07.031

Koval, M., Billaud, M., Straub, A. C., Johnstone, S. R., Zarbock, A., Duling, B. R., & Isakson, B. E. (2011). Spontaneous Lung Dysfunction and Fibrosis in Mice Lacking Connexin 40 and Endothelial Cell Connexin 43. AMERICAN JOURNAL OF PATHOLOGY, 178(6), 2536-2546. doi:10.1016/j.ajpath.2011.02.045

Billaud, M., Lohman, A. W., Straub, A. C., Looft-Wilson, R., Johnstone, S. R., Araj, C. A., . . . Isakson, B. E. (2011). Pannexin1 Regulates α1-Adrenergic Receptor-Mediated Vasoconstriction. CIRCULATION RESEARCH, 109(1), 80-U284. doi:10.1161/CIRCRESAHA.110.237594

Billaud, M., Ross, J. A., Greyson, M. A., Bruce, A. C., Seaman, S. A., Heberlein, K. R., . . . Isakson, B. E. (2011). A New Method for In Vivo Visualization of Vessel Remodeling Using a Near-Infrared Dye. MICROCIRCULATION, 18(3), 163-171. doi:10.1111/j.1549-8719.2011.00085.x

Sandilos, J. K., Chekeni, F. B., Elliott, M. R., Walk, S. F., Kinchen, J. M., Lazarowski, E. R., . . . Bayliss, D. A. (2011). Caspases Mediate Pannexin 1 Channel Activation in Apoptotic Cells. Biophysical Journal, 100(3), 101a. doi:10.1016/j.bpj.2010.12.759

Straub, A. C., Billaud, M., Best, A. K., & Isakson, B. E. (2011). Apical and basal endothelial nitric oxide release each regulate distinct subcellular functions within the vessel wall. FASEB JOURNAL, 25. Retrieved from https://www.webofscience.com/

Isakson, B. E., Billaud, M., Lohman, A. W., Straub, A. C., Sandilos, J. K., & Bayliss, D. A. (2011). S-nitrosylation of pannexin 1 reduces channel permeability, potentially regulating vasoconstriction. JOURNAL OF VASCULAR RESEARCH, 48, 8. Retrieved from https://www.webofscience.com/

Heberlein, K., Straub, A. C., Best, A. K., Wojta, J., & Isakson, B. E. (2011). Nicotinamide phosphoribosyl transferase coordinates stabilization of plasminogen activator inhibitor-1 mRNA at the myoendothelial junction. FASEB JOURNAL, 25. Retrieved from https://www.webofscience.com/

Billaud, M., Lohman, A. W., Sandilos, J. K., Bayliss, D. A., & Isakson, B. E. (2011). Exclusive interaction between α1D-adrenergic receptor and pannexin 1 can mediate vasoconstriction. JOURNAL OF VASCULAR RESEARCH, 48, 118. Retrieved from https://www.webofscience.com/

Straub, A., Billaud, M., Johnstone, S. R., Best, A. K., Looft-Wilson, R., Gaston, B., . . . Isakson, B. E. (2011). Compartmentalized redox signaling at the myoendothelial junction regulates heterocellular communication in the vessel wall. FASEB JOURNAL, 25. Retrieved from https://www.webofscience.com/

Isakson, B. E., & Billaud, M. (2011). Expression and function of pannexins in the vasculature. JOURNAL OF VASCULAR RESEARCH, 48, 6. Retrieved from https://www.webofscience.com/

Cechova, S., Zeng, Q., Billaud, M., Straub, A., Isakson, B., & Thu, L. (2011). Deletion Of Collectrin, An Ace-2 Homologue, Results In Altered eNOS Expression And Impaired Endothelium-dependent Vasorelaxation. HYPERTENSION, 58(5), E150. Retrieved from https://www.webofscience.com/

Straub, A. C., Billaud, M., Johnstone, S. R., Best, A. K., Yemen, S., Dwyer, S. T., . . . Isakson, B. E. (2011). Compartmentalized Connexin 43 S-Nitrosylation/Denitrosylation Regulates Heterocellular Communication in the Vessel Wall. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(2), 399-U353. doi:10.1161/ATVBAHA.110.215939

Chekeni, F. B., Elliott, M. R., Sandilos, J. K., Walk, S. F., Kinchen, J. M., Lazarowski, E. R., . . . Ravichandran, K. S. (2010). Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. NATURE, 467(7317), 863-U136. doi:10.1038/nature09413

Kadl, A., Meher, A. K., Sharma, P. R., Lee, M. Y., Doran, A. C., Johnstone, S. R., . . . Leitinger, N. (2010). Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2. CIRCULATION RESEARCH, 107(6), 737-U155. doi:10.1161/CIRCRESAHA.109.215715

Johnstone, S. R., Best, A. K., Wright, C. S., Isakson, B. E., Errington, R. J., & Martin, P. E. (2010). Enhanced Connexin 43 Expression Delays Intra-Mitoitc Duration and Cell Cycle Traverse Independently of Gap Junction Channel Function. JOURNAL OF CELLULAR BIOCHEMISTRY, 110(3), 772-782. doi:10.1002/jcb.22590

Heberlein, K., Straub, A. C., Best, A. K., Looft-Wilson, R. C., & Isakson, B. E. (2009). Plasminogen activator inhibitor-1 can regulate myoendothelial junction formation. FASEB JOURNAL, 23. Retrieved from https://www.webofscience.com/

Heberlein, K. R., Straub, A. C., Best, A. K., Greyson, M. A., Looft-Wilson, R. C., Sharma, P. R., . . . Isakson, B. E. (2010). Plasminogen Activator Inhibitor-1 Regulates Myoendothelial Junction Formation. CIRCULATION RESEARCH, 106(6), 1092-1102. doi:10.1161/CIRCRESAHA.109.215723

Wang, L., Yin, J., Isakson, B., de Wit, C., & Kuebler, W. M. (2010). A critical role for connexin 40 in hypoxia induced pulmonary vasoconstriction. FASEB JOURNAL, 24. Retrieved from https://www.webofscience.com/

Straub, A. C., Johnstone, S. R., Best, A. K., Palmer, L., & Isakson, B. E. (2010). Compartmentalized nitric oxide signaling at the myoendothelial junction can regulate gap junction communication. FASEB JOURNAL, 24. Retrieved from https://www.webofscience.com/

Heberlein, K., Han, J., Zorn, G., Kaun, C., Straub, A. C., Best, A. K., . . . Isakson, B. E. (2010). The potential for localized translation and induction of plasminogen activator inhibitor-1 at the myoendothelial junction in response to TNF-alpha. FASEB JOURNAL, 24. Retrieved from https://www.webofscience.com/

Chen, C. -H., Beard, R. S., Straub, A. C., Heberlein, K., Isakson, B. E., & Bearden, S. E. (2010). Homocysteine Modulates the Density and Composition of Myoendothelial Junctions. CIRCULATION, 122(21). Retrieved from https://www.webofscience.com/