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Francis H. Shen

Francis H. Shen

Professor, Orthopaedic Surgery

Primary Location
PO Box 800159
400 Ray C . Hunt Dr., Ste. 330
Primary Phone Number

Bio & Overview

Cell and gene mediate spinal fusion, spinal cord injury and regeneration.

Academic Information

Department
Orthopaedic Surgery
Academic Title
Associate Professor

Primary Education

  • BS, Engineering, University of Michigan, 1992

Other Affiliations

  • Member, Cancer Cell Signaling Program

Research Interests

Cell and gene mediate spinal fusion, spinal cord injury and regeneration.

Selected Publications

2022

Cho, W., Le, J. T., Shimer, A. L., Werner, B. C., Glaser, J. A., & Shen, F. H. (2022). The Feasibility of Translaminar Screws in the Subaxial Cervical Spine: Computed Tomography and Cadaveric Validation. CLINICS IN ORTHOPEDIC SURGERY, 14(1), 105-111. doi:10.4055/cios21059

2021

Shen, F. H., Gasbarrini, A., Lui, D. F., Reynolds, J., Capua, J., & Boriani, S. (2022). Integrated Custom Composite Polyetheretherketone/Carbon fiber (PEEK/CF) Vertebral Body Replacement (VBR) in the Treatment of Bone Tumors of the Spine A Preliminary Report From a Multicenter Study. SPINE, 47(3), 252-260. doi:10.1097/BRS.0000000000004177

Shimer, A. L., & Shen, F. H. (2021). Not Just Shoulders and Knees: An Athlete Has a Spine too! Preface. CLINICS IN SPORTS MEDICINE, 40(3), XI-XII. doi:10.1016/j.csm.2021.04.004

Shen, F. H., Woods, D., Miller, M., Murrell, B., & Vadapalli, S. (2021). Use of the dual construct lowers rod strains in flexion-extension and lateral bending compared to two-rod and two-rod satellite constructs in a cadaveric spine corpectomy model. SPINE JOURNAL, 21(12), 2104-2111. doi:10.1016/j.spinee.2021.05.022

2019

Xiao, L., Huang, R., Zhang, Y., Li, T., Dai, J., Nannapuneni, N., . . . Li, X. (2019). A New Formyl Peptide Receptor-1 Antagonist Conjugated Fullerene Nanoparticle for Targeted Treatment of Degenerative Disc Diseases. ACS APPLIED MATERIALS & INTERFACES, 11(42), 38405-38416. doi:10.1021/acsami.9b11783

Aghdasi, B., Li, X., George, J., & Shen, F. H. (2019). Fixation techniques in revision spine surgery. Seminars in Spine Surgery, 31(2), 87-95. doi:10.1053/j.semss.2019.03.007

Singla, A., Qureshi, R., Chen, D. Q., Nourbakhsh, A., Hassanzadeh, H., Shimer, A. L., & Shen, F. H. (2019). Risk of Surgical Site Infection and Mortality Following Lumbar Fusion Surgery in Patients With Chronic Steroid Usage and Chronic Methicillin-Resistant Staphylococcus aureus Infection.. Spine, 44(7), E408-E413. doi:10.1097/brs.0000000000002864

Labaran, L. A., Puvanesarajah, V., Rao, S. S., Chen, D., Shen, F. H., Jain, A., & Hassanzadeh, H. (2019). Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy. GLOBAL SPINE JOURNAL, 9(8), 807-812. doi:10.1177/2192568219833656

Shen, F. H. (2019). "Should we measure?" and more importantly, "should we report?" Perspective from an adult orthopaedic deformity surgeon. SKELETAL RADIOLOGY, 48(6), 835-836. doi:10.1007/s00256-019-3154-2

Xiao, L., Majumdar, R., Dai, J., Li, Y., Xie, L., Shen, F. H., . . . Li, X. (2019). Molecular Detection and Assessment of Intervertebral Disc Degeneration via a Collagen Hybridizing Peptide. ACS BIOMATERIALS SCIENCE & ENGINEERING, 5(4), 1661-1667. doi:10.1021/acsbiomaterials.9b00070

Chen, D. Q., Shimer, A. L., Li, X., Hassanzadeh, H., Shen, F. H., & Singla, A. (2019). Unplanned Immediate Return to Operating Room After Spine Surgery Significance of Immediate Postoperative Radiographs. SPINE, 44(4), 258-262. doi:10.1097/BRS.0000000000002797

Horowitz, J. A., Puvanesarajah, V., Jain, A., Raad, M., Gjolaj, J. P., Shen, F. H., & Hassanzadeh, H. (2019). Fragility Fracture Risk in Elderly Patients With Cervical Myelopathy. SPINE, 44(2), 96-102. doi:10.1097/BRS.0000000000002762

2018

Singla, A., Qureshi, R., Chen, D. Q., Nourbakhsh, A., Hassanzadeh, H., Shimer, A. L., & Shen, F. H. (2019). Risk of Surgical Site Infection and Mortality Following Lumbar Fusion Surgery in Patients With Chronic Steroid Usage and Chronic Methicillin-Resistant Staphylococcus aureus Infection. SPINE, 44(7), E408-E413. doi:10.1097/BRS.0000000000002864

Horowitz, J. A., Puvanesarajah, V., Jain, A., Li, X. J., Shimer, A. L., Shen, F. H., & Hassanzadeh, H. (2018). Rheumatoid Arthritis Is Associated With an Increased Risk of Postoperative Infection and Revision Surgery in Elderly Patients Undergoing Anterior Cervical Fusion. SPINE, 43(17), E1040-E1044. doi:10.1097/BRS.0000000000002614

Lambrechts, M. J., Wiegers, N. W., Ituarte, F., Shen, F. H., & Nourbakhsh, A. (2018). Safe zone for irrigation and debridement of psoas abscess through a dorsal spinal approach. SURGICAL AND RADIOLOGIC ANATOMY, 40(11), 1217-1221. doi:10.1007/s00276-018-2063-8

Amin, R., Puvanesarajah, V., Qureshi, R., Jain, A., Kebaish, K., Shen, F. H., & Hassanzadeh, H. (2018). Lumbar Spine Fusion Surgery in Solid Organ Transplant Recipients Is Associated With Increased Medical Complications and Mortality. SPINE, 43(9), 617-621. doi:10.1097/BRS.0000000000002393

Qureshi, R., Werner, B., Puvanesarajah, V., Horowitz, J. A., Jain, A., Sciubba, D., . . . Hassanzadeh, H. (2018). Factors Affecting Long-Term Postoperative Narcotic Use in Discectomy Patients. WORLD NEUROSURGERY, 112, E640-E644. doi:10.1016/j.wneu.2018.01.113

Pierce, J. L., Donahue, J. H., Nacey, N. C., Quirk, C. R., Perry, M. T., Faulconer, N., . . . Shen, F. H. (2018). Spinal Hematomas: What a Radiologist Needs to Know. RADIOGRAPHICS, 38(5), 1516-1535. doi:10.1148/rg.2018180099

Nourbakhsh, A., Wiegers, N. W., & Shen, F. H. (2018). Posterior identification and exposure of the V3 segment of the vertebral artery. JOURNAL OF CRANIOVERTEBRAL JUNCTION AND SPINE, 9(1), 44-49. doi:10.4103/jcvjs.JCVJS_125_17

Puvanesarajah, V., Cancienne, J. M., Werner, B. C., Jain, A., Singla, A., Shimer, A. L., . . . Hassanzadeh, H. (2018). Perioperative Complications Associated With Posterolateral Spine Fusions A Study of Elderly Medicare Beneficiaries. SPINE, 43(1), 16-21. doi:10.1097/BRS.0000000000001771

2017

Qureshi, R., Puvanesarajah, V., Jain, A., Shimer, A. L., Shen, F. H., & Hassanzadeh, H. (2017). A Comparison of Anterior and Posterior Lumbar Interbody Fusions Complications, Readmissions, Discharge Dispositions, and Costs. SPINE, 42(24), 1865-1870. doi:10.1097/BRS.0000000000002248

Xiao, L., Hong, K., Roberson, C., Ding, M., Fernandez, A., Shen, F., . . . Li, X. (2018). Hydroxylated Fullerene: A Stellar Nanomedicine to Treat Lumbar Radiculopathy via Antagonizing TNF-α-lnduced Ion Channel Activation, Calcium Signaling, and Neuropeptide Production. ACS BIOMATERIALS SCIENCE & ENGINEERING, 4(1), 266-277. doi:10.1021/acsbiomaterials.7b00735

Shen, F. H., Qureshi, R., Tyger, R., Lehman, R., Singla, A., Shimer, A., & Hassanzadeh, H. (2018). Use of the "dual construct" for the management of complex spinal reconstructions. SPINE JOURNAL, 18(3), 482-490. doi:10.1016/j.spinee.2017.08.235

Puvanesarajah, V., Jain, A., Cancienne, J. M., Stein, B. E., Novicoff, W. M., Shimer, A. L., . . . Hassanzadeh, H. (2017). BMP Use and the Risk of Revision Surgery After Long Posterolateral Fusions in the Elderly. CLINICAL SPINE SURGERY, 30(7), E931-E937. doi:10.1097/BSD.0000000000000489

Cho, W., Le, J. T., Shimer, A. L., Werner, B. C., Glaser, J. A., & Shen, F. H. (2017). Anatomy of Lamina in the Subaxial Cervical Spine With the Special Reference to Translaminar Screws CT and Cadaveric Analysis With Screw Trajectory Simulation. CLINICAL SPINE SURGERY, 30(5), E535-E539. doi:10.1097/BSD.0000000000000159

Qureshi, R., Puvanesarajah, V., Jain, A., Kebaish, K., Shimer, A., Shen, F., & Hassanzadeh, H. (2017). Cost Implications of Primary Versus Revision Surgery in Adult Spinal Deformity. WORLD NEUROSURGERY, 104, 68-73. doi:10.1016/j.wneu.2017.05.002

Puvanesarajah, V., Jain, A., Shimer, A. L., Singla, A., Shen, F., & Hassanzadeh, H. (2017). Complications and Mortality Following One to Two-Level Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 80 Years of Age. SPINE, 42(9), E509-E514. doi:10.1097/BRS.0000000000001876

Puvanesarajah, V., Jain, A., Shimer, A. L., Li, X., Singla, A., Shen, F., & Hassanzadeh, H. (2017). Complications and Mortality Following 1 to 2 Level Lumbar Fusion Surgery in Patients Above 80 Years of Age.. Spine, 42(6), 437-441. doi:10.1097/brs.0000000000001759

Singla, A., Yang, S., Werner, B. C., Cancienne, J. M., Nourbakhsh, A., Shimer, A. L., . . . Shen, F. H. (2017). The impact of preoperative epidural injections on postoperative infection in lumbar fusion surgery. JOURNAL OF NEUROSURGERY-SPINE, 26(5), 645-649. doi:10.3171/2016.9.SPINE16484

Cancienne, J. M., Werner, B. C., Hassanzadeh, H., Singla, A., Shen, F. H., & Shimer, A. L. (2017). The Association of Perioperative Glycemic Control with Deep Postoperative Infection After Anterior Cervical Discectomy and Fusion in Patients with Diabetes. WORLD NEUROSURGERY, 102, 13-17. doi:10.1016/j.wneu.2017.02.118

Puvanesarajah, V., Cancienne, J. M., Shimer, A. L., Shen, F. H., & Hassanzadeh, H. (2017). Complications after Fusion for Thoracolumbar Fractures in Patients with Ankylosing Spondylitis. GLOBAL SPINE JOURNAL, 7(1), 28-32. doi:10.1055/s-0036-1583175

Cancienne, J. M., Werner, B. C., Puvanesarajah, V., Hassanzadeh, H., Singla, A., Shen, F. H., & Shimer, A. L. (2017). Does the Timing of Preoperative Epidural Steroid Injection Affect Infection Risk After ACDF or Posterior Cervical Fusion?. Spine, 42(2), 71-77. doi:10.1097/brs.0000000000001661

Puvanesarajah, V., Werner, B. C., Cancienne, J. M., Jain, A., Pehlivan, H., Shimer, A. L., . . . Hassanzadeh, H. (2017). Morbid Obesity and Lumbar Fusion in Patients Older Than 65 Years Complications, Readmissions, Costs, and Length of Stay. SPINE, 42(2), 122-127. doi:10.1097/BRS.0000000000001692

Puvanesarajah, V., Hassanzadeh, H., Shimer, A. L., Shen, F. H., & Singla, A. (2017). Readmission Rates, Reasons, and Risk Factors Following Anterior Cervical Fusion for Cervical Spondylosis in Patients Above 65 Years of Age. SPINE, 42(2), 78-84. doi:10.1097/BRS.0000000000001663

Xiao, L., Ding, M., Zhang, Y., Chordia, M., Pan, D., Shimer, A., . . . Li, X. (2017). A Novel Modality for Functional Imaging in Acute Intervertebral Disk Herniation via Tracking Leukocyte Infiltration. MOLECULAR IMAGING AND BIOLOGY, 19(5), 703-713. doi:10.1007/s11307-016-1038-6

Puvanesarajah, V., Jain, A., Cancienne, J. M., Shimer, A. L., Singla, A., Shen, F., & Hassanzadeh, H. (2017). Complication and Reoperation Rates Following Surgical Management of Cervical Spondylotic Myelopathy in Medicare Beneficiaries. SPINE, 42(1), 1-7. doi:10.1097/BRS.0000000000001639

2016

Puvanesarajah, V., Nourbakhsh, A., Hassanzadeh, H., Shimer, A. L., Shen, F. H., & Singla, A. (2016). Readmission Rates, Reasons, and Risk Factors in Elderly Patients Treated With Lumbar Fusion for Degenerative Pathology. SPINE, 41(24), 1933-1938. doi:10.1097/BRS.0000000000001631

Reid, R., Puvanesarajah, V., Kandil, A., Yildirim, B., Shimer, A. L., Singla, A., . . . Hassanzadeh, H. (2017). Factors Associated with Patient-Initiated Telephone Calls After Spine Surgery. WORLD NEUROSURGERY, 98, 625-631. doi:10.1016/j.wneu.2016.11.004

Puvanesarajah, V., Jain, A., Hess, D. E., Shimer, A. L., Shen, F. H., & Hassanzadeh, H. (2016). Complications and Mortality After Lumbar Spinal Fusion in Elderly Patients With Late Stage Renal Disease. SPINE, 41(21), E1298-E1302. doi:10.1097/BRS.0000000000001618

Singla, A., Shimer, A. L., & Shen, F. H. (2016). Reply to the Letter to the Editor: Preoperative epidural injections are associated with increased risk of infection after single-level lumbar decompression. SPINE JOURNAL, 16(10), 1283. doi:10.1016/j.spinee.2016.05.006

Yildirim, B., Puvanesarajah, V., An, H. S., Novicoff, W. M., Jain, A., Shen, F. H., & Hassanzadeh, H. (2016). Lumbosacral Epidural Lipomatosis: A Retrospective Matched Case-Control Database Study. WORLD NEUROSURGERY, 96, 209-214. doi:10.1016/j.wneu.2016.08.125

Puvanesarajah, V., Jain, A., Shimer, A. L., Shen, F. H., & Hassanzadeh, H. (2016). The Effect of Coagulopathies on Perioperative Complications and Clinical Outcomes in Patients Treated With Posterior Lumbar Fusions. SPINE, 41(17), E1063-E1068. doi:10.1097/BRS.0000000000001550

Lawrence, D. A., Trotta, B., Shen, F. H., Druzgal, J. T., & Fox, M. G. (2016). Imaging characteristics of cervical spine extra-arachnoid fluid collections managed conservatively. SKELETAL RADIOLOGY, 45(9), 1285-1289. doi:10.1007/s00256-016-2428-1

Cancienne, J. M., Werner, B. C., Loeb, A. E., Yang, S. S., Hassanzadeh, H., Singla, A., . . . Shimer, A. L. (2016). The Effect of Local Intraoperative Steroid Administration on the Rate of Postoperative Dysphagia Following ACDF. SPINE, 41(13), 1084-1088. doi:10.1097/BRS.0000000000001407

Puvanesarajah, V., Shen, F. H., Cancienne, J. M., Novicoff, W. M., Jain, A., Shimer, A. L., & Hassanzadeh, H. (2016). Risk factors for revision surgery following primary adult spinal deformity surgery in patients 65 years and older. JOURNAL OF NEUROSURGERY-SPINE, 25(4), 486-493. doi:10.3171/2016.2.SPINE151345

Cancienne, J. M., Werner, B. C., Puvanesarajah, V., Hassanzadeh, H., Singla, A., Shen, F. H., & Shimer, A. L. (2017). Does the Timing of Preoperative Epidural Steroid Injection Affect Infection Risk After ACDF or Posterior Cervical Fusion?. SPINE, 42(2), 71-77. doi:10.1097/BRS.0000000000001661

Werner, B. C., Samartzis, D., & Shen, F. H. (2016). Spinal Fractures in Patients With Ankylosing Spondylitis: Etiology, Diagnosis, and Management. JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 24(4), 241-249. doi:10.5435/JAAOS-D-14-00149

Yeh, C. -H., Jin, L., Shen, F., Balian, G., & Li, X. J. (2016). miR-221 attenuates the osteogenic differentiation of human annulus fibrosus cells. SPINE JOURNAL, 16(7), 896-904. doi:10.1016/j.spinee.2016.03.026

Diduch, B. K., Hudson, K., Resch, J. E., Shen, F., Broshek, D. K., Brady, W., . . . Miller, M. D. (2016). TREATMENT OF HEAD AND NECK INJURIES IN THE HELMETED ATHLETE. JBJS REVIEWS, 4(3). doi:10.2106/JBJS.RVW.15.00077

Stensby, J. D., Kaliney, R. W., Alford, B., Shen, F. H., Patrie, J. T., & Fox, M. G. (2016). Radiographic Appearance of Transforaminal Lumbar Interbody Fusion Performed With and Without Recombinant Human Morphogenetic Protein-2. AMERICAN JOURNAL OF ROENTGENOLOGY, 206(3), 588-594. doi:10.2214/AJR.15.14503

Samartzis, D., Kalluri, P., Herman, J., Lubicky, J. P., & Shen, F. H. (2016). "Clinical triad" findings in pediatric Klippel-Feil patients. SCOLIOSIS AND SPINAL DISORDERS, 11. doi:10.1186/s13013-016-0075-x

2015

Louie, P. K., Hassanzadeh, H., Shimer, A. L., & Shen, F. H. (2015). Intraoperative neurophysiologic monitoring during spinal osteotomies. Seminars in Spine Surgery, 27(4), 222-228. doi:10.1053/j.semss.2015.04.008

Louie, P. K., Khanna, A. J., Hassanzadeh, H., & Kebaish, K. M. (2015). Intraoperative neurophysiologic monitoring in high-grade spondylolisthesis. Seminars in Spine Surgery, 27(4), 217-221. doi:10.1053/j.semss.2015.04.007

Yang, S., Werner, B. C., Cancienne, J. M., Hassanzadeh, H., Shimer, A. L., Shen, F. H., & Singla, A. (2016). Preoperative epidural injections are associated with increased risk of infection after single-level lumbar decompression. SPINE JOURNAL, 16(2), 191-196. doi:10.1016/j.spinee.2015.07.439

Li, X. J., Jin, L., Hassanzadeh, H., & Shen, F. H. (2015). State of the art and future of stem cells in spine. Seminars in Spine Surgery, 27(2), 93-102. doi:10.1053/j.semss.2015.03.006

Vavken, P., Ganal-Antonio, A. K. B., Quidde, J., Shen, F. H., Chapman, J. R., & Samartzis, D. (2015). Fundamentals of Clinical Outcomes Assessment for Spinal Disorders: Clinical Outcome Instruments and Applications. GLOBAL SPINE JOURNAL, 5(4), 329-338. doi:10.1055/s-0034-1396046

Vavken, P., Ganal-Antonio, A. K. B., Shen, F. H., Chapman, J. R., & Samartzis, D. (2015). Fundamentals of Clinical Outcomes Assessment for Spinal Disorders: Study Designs, Methodologies, and Analyses. GLOBAL SPINE JOURNAL, 5(2), 156-164. doi:10.1055/s-0035-1547525

Shen, F. H. (2015). Reviewer's comment concerning "anterior cervical discectomy versus corpectomy for multilevel cervical spondylotic myelopathy: a meta-analysis" (ESJO-D-14-00408R2 by Shan-Wen Xiao, Hua Jiang, Li-Jing Yang and Zeng-Ming Xiao).. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 24(1), 40. doi:10.1007/s00586-014-3608-0

2014

Cho, W., Le, J. T., Shimer, A. L., Werner, B. C., Glaser, J. A., & Shen, F. H. (2015). The insertion technique of translaminar screws in the thoracic spine: computed tomography and cadaveric validation. SPINE JOURNAL, 15(2), 309-313. doi:10.1016/j.spinee.2014.09.013

Cho, W., Le, J. T., Shimer, A. L., Werner, B. C., Glaser, J. A., & Shen, F. H. (2014). Anatomy of Lamina in the Subaxial Cervical Spine with the Special Reference to Translaminar Screws: CT and Cadaveric Analysis with Screw Trajectory Simulation.. Journal of spinal disorders & techniques. doi:10.1097/bsd.0000000000000159

Fox, M. G., Goldberg, J. M., Gaskin, C. M., Barr, M. S., Patrie, J. T., Shen, F. H., & Alford, B. (2014). MRI of transforaminal lumbar interbody fusion: imaging appearance with and without the use of human recombinant bone morphogenetic protein-2 (rhBMP-2). SKELETAL RADIOLOGY, 43(9), 1247-1255. doi:10.1007/s00256-014-1917-3

Voleti, P. B., Shen, F. H., & Arlet, V. (2014). Failure of Monoaxial Pedicle Screws at the Distal End of Scoliosis Constructs: A Case Series.. Spine deformity, 2(2), 110-121. doi:10.1016/j.jspd.2013.11.004

Yang, D., Wang, D., Shimer, A., Shen, F. H., Li, X., & Yang, X. (2014). Glutathione protects human nucleus pulposus cells from cell apoptosis and inhibition of matrix synthesis. CONNECTIVE TISSUE RESEARCH, 55(2), 132-139. doi:10.3109/03008207.2013.876421

Yang, X., Jin, L., Yao, L., Shen, F. H., Shimer, A. L., & Li, X. (2014). Antioxidative nanofullerol prevents intervertebral disk degeneration. INTERNATIONAL JOURNAL OF NANOMEDICINE, 9, 2419-2430. doi:10.2147/IJN.S60853

Jin, L., Liu, Q., Scott, P., Zhang, D., Shen, F., Balian, G., & Li, X. (2014). Annulus Fibrosus Cell Characteristics Are a Potential Source of Intervertebral Disc Pathogenesis. PLOS ONE, 9(5). doi:10.1371/journal.pone.0096519

2013

Werner, B. C., Li, X., & Shen, F. H. (2014). Stem cells in preclinical spine studies. SPINE JOURNAL, 14(3), 542-551. doi:10.1016/j.spinee.2013.08.031

Liang, H., Li, X., Shimer, A. L., Balian, G., & Shen, F. H. (2014). A novel strategy of spine defect repair with a degradable bioactive scaffold preloaded with adipose-derived stromal cells. SPINE JOURNAL, 14(3), 445-454. doi:10.1016/j.spinee.2013.09.045

Cho, W., Mason, J. R., Smith, J. S., Shimer, A. L., Wilson, A. S., Shaffrey, C. I., . . . Arlet, V. (2013). Failure of lumbopelvic fixation after long construct fusions in patients with adult spinal deformity: clinical and radiographic risk factors. JOURNAL OF NEUROSURGERY-SPINE, 19(4), 445-453. doi:10.3171/2013.6.SPINE121129

Liu, Q., Jin, L., Mahon, B. H., Chordia, M. D., Shen, F. H., & Li, X. (2013). Novel Treatment of Neuroinflammation Against Low Back Pain by Soluble Fullerol Nanoparticles. SPINE, 38(17), 1443-1451. doi:10.1097/BRS.0b013e31828fc6b7

Werner, B. C., Shen, F. H., & Shimer, A. L. (2013). Primary cervical amyloidoma: a case report and review of the literature. SPINE JOURNAL, 13(10), E1-E7. doi:10.1016/j.spinee.2013.04.003

Liu, Q., Jin, L., Shen, F. H., Balian, G., & Li, X. J. (2013). Fullerol nanoparticles suppress inflammatory response and adipogenesis of vertebral bone marrow stromal cells-a potential novel treatment for intervertebral disc degeneration. SPINE JOURNAL, 13(11), 1571-1580. doi:10.1016/j.spinee.2013.04.004

Shen, F. H. -T., & Samartzis, D. (2013). Operative Management of a Sacral Gunshot Injury via Minimally Invasive Techniques and Instrumentation.. Asian spine journal, 7(1), 44-49. doi:10.4184/asj.2013.7.1.44

Jin, L., Feng, G., Reames, D. L., Shimer, A. L., Shen, F. H., & Li, X. (2013). The effects of simulated microgravity on intervertebral disc degeneration. SPINE JOURNAL, 13(3), 235-242. doi:10.1016/j.spinee.2012.01.022

Shen, F. H., Werner, B. C., Liang, H., Shang, H., Yang, N., Li, X., . . . Katz, A. J. (2013). Implications of adipose-derived stromal cells in a 3D culture system for osteogenic differentiation: an in vitro and in vivo investigation. SPINE JOURNAL, 13(1), 32-43. doi:10.1016/j.spinee.2013.01.002

2012

Werner, B. C., Yang, S., Shen, F. H., & Shimer, A. L. (2012). Cauda Equina in the Setting of Thoracolumbar Trauma: Is Early Decompression Indicated?. Seminars in Spine Surgery, 24(4), 226-234. doi:10.1053/j.semss.2012.05.005

Shen, F. H., Mason, J. R., Shimer, A. L., & Arlet, V. M. (2013). Pelvic fixation for adult scoliosis. EUROPEAN SPINE JOURNAL, 22, S265-S275. doi:10.1007/s00586-012-2525-3

Zhang, D., Jin, L., Reames, D. L., Shen, F. H., Shimer, A. L., & Li, X. (2013). Intervertebral Disc Degeneration and Ectopic Bone Formation in Apolipoprotein E Knockout Mice. JOURNAL OF ORTHOPAEDIC RESEARCH, 31(2), 210-217. doi:10.1002/jor.22216

Haller, J. M., Iwanik, M., & Shen, F. H. (2012). Clinically Relevant Anatomy of Recurrent Laryngeal Nerve. SPINE, 37(2), 97-100. doi:10.1097/BRS.0b013e31821f3e86

Jin, L., Wan, Y., Shimer, A. L., Shen, F. H., & Li, X. J. (2012). Intervertebral disk-like biphasic scaffold-demineralized bone matrix cylinder and poly(polycaprolactone triol malate)-for interbody spine fusion. JOURNAL OF TISSUE ENGINEERING, 3(1). doi:10.1177/2041731412454420

2011

Eager, M., Shimer, A., Jahangiri, F. R., Shen, F., & Arlet, V. (2011). Intraoperative neurophysiological monitoring (IONM): lessons learned from 32 case events in 2069 spine cases.. American journal of electroneurodiagnostic technology, 51(4), 247-263. doi:10.1080/1086508x.2011.11079827

Haller, J. M., Iwanik, M., & Shen, F. H. (2011). Clinically Relevant Anatomy of High Anterior Cervical Approach. SPINE, 36(25), 2116-2121. doi:10.1097/BRS.0b013e31820408af

Samartzis, D., Kalluri, P., Herman, J., Lubicky, J. P., & Shen, F. H. (2011). Cervical Scoliosis in the Klippel-Feil Patient. SPINE, 36(23), E1501-E1508. doi:10.1097/BRS.0b013e31823145e4

Liang, H., Werner, B. C., Balian, G., & Shen, F. H. (2011). Bioengineering Techniques with Human Adipose-Derived Stromal Cells. The Spine Journal, 11(10), S71. doi:10.1016/j.spinee.2011.08.177

Beazell, J. R., Grindstaff, T. L., Hart, J. M., Magrum, E. M., Cullaty, M., & Shen, F. H. (2011). Changes in Lateral Abdominal Muscle Thickness During an Abdominal Drawing-In Maneuver in Individuals With and Without Low Back Pain. RESEARCH IN SPORTS MEDICINE, 19(4), 271-282. doi:10.1080/15438627.2011.608053

Werner, B. C., Hogan, M. V., & Shen, F. H. (2011). Candida lusitaniae discitis after discogram in an immunocompetent patient. SPINE JOURNAL, 11(10), E1-E6. doi:10.1016/j.spinee.2011.09.004

Karppinen, J., Shen, F. H., Luk, K. D. K., Andersson, G. B. J., Cheung, K. M. C., & Samartzis, D. (2011). Management of Degenerative Disk Disease and Chronic Low Back Pain. ORTHOPEDIC CLINICS OF NORTH AMERICA, 42(4), 513-+. doi:10.1016/j.ocl.2011.07.009

Cho, W., Shimer, A. L., & Shen, F. H. (2011). Complications Associated with Posterior Lumbar Surgery. Seminars in Spine Surgery, 23(2), 101-113. doi:10.1053/j.semss.2010.12.013

Werner, B. C., Shen, F. H., & Shimer, A. L. (2011). Infections After Lumbar Spine Surgery: Avoidance and Treatment. Seminars in Spine Surgery, 23(2), 142-150. doi:10.1053/j.semss.2010.12.017

Liang, H., Ma, S. -Y., Mohammad, K., Guise, T. A., Balian, G., & Shen, F. H. (2011). The Reaction of Bone to Tumor Growth From Human Breast Cancer Cells in a Rat Spine Single Metastasis Model. SPINE, 36(7), 497-504. doi:10.1097/BRS.0b013e3181d8906f

Yang, X., Wang, D., Hao, J., Gong, M., Arlet, V., Balian, G., . . . Li, X. J. (2011). Enhancement of Matrix Production and Cell Proliferation in Human Annulus Cells Under Bioreactor Culture. TISSUE ENGINEERING PART A, 17(11-12), 1595-1603. doi:10.1089/ten.tea.2010.0449

2010

Eager, M., Jahangiri, F., Shimer, A., Shen, F., & Arlet, V. (2010). Intraoperative neuromonitoring: lessons learned from 32 case events in 2095 spine cases.. Evidence-based spine-care journal, 1(2), 58-61. doi:10.1055/s-0028-1100917

Shen, F. H., & Haller, J. (2010). Extracavitary Approach to the Thoracolumbar Spine. Seminars in Spine Surgery, 22(2), 84-91. doi:10.1053/j.semss.2009.12.007

Liang, H., Wang, K., Shimer, A. L., Li, X., Balian, G., & Shen, F. H. (2010). Use of a bioactive scaffold for the repair of bone defects in a novel reproducible vertebral body defect model. BONE, 47(2), 197-204. doi:10.1016/j.bone.2010.05.023

Hicks, J. M., Singla, A., Shen, F. H., & Arlet, V. (2010). Complications of Pedicle Screw Fixation in Scoliosis Surgery A Systematic Review. SPINE, 35(11), E465-E470. doi:10.1097/BRS.0b013e3181d1021a

Damon, A. M., Lessley, D. J., Salzar, R. S., Bass, C. R., Shen, F. H., Paskoff, G. R., & Shender, B. S. (2010). Kinematic Response of the Spine During Simulated Aircraft Ejections. AVIATION SPACE AND ENVIRONMENTAL MEDICINE, 81(5), 453-459. doi:10.3357/ASEM.2688.2010

Feng, G., Yang, X., Shang, H., Marks, I. W., Shen, F. H., Katz, A., . . . Li, X. (2010). Multipotential Differentiation of Human Anulus Fibrosus Cells An in Vitro Study. JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 92A(3), 675-685. doi:10.2106/JBJS.H.01672

Samartzis, D., Wein, S. M., Shen, F. H., Beazell, J., Francke, E. I., & Anderson, D. G. (2010). A Revisitation of Distractive-Extension Injuries of the Subaxial Cervical Spine A Cadaveric and Radiographic Soft Tissue Analysis. SPINE, 35(4), 395-402. doi:10.1097/BRS.0b013e3181c9fa35

Samartzis, D., Shen, F. H., Herman, J., & Mardjetko, S. M. (2010). Atlantoaxial Rotatory Fixation in the Setting of Associated Congenital Malformations A Modified Classification System. SPINE, 35(4), E119-E127. doi:10.1097/BRS.0b013e3181c9f957