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Irving L. Kron, MD

Irving L. Kron, MD

Professor of Surgery Emeritus, Surgery

Primary Location
PO Box 800679
Charlottesville, Virginia 22903
Primary Phone Number

Bio & Overview

Academic Information

Department
Surgery
Academic Title
Professor

Other Appointments

  • Molecular Physiology and Biological Physics

Other Affiliations

  • Cardiovascular Research Center
  • BIMS

Research Interests

Transplantation and aortic aneurysms

Selected Publications

2025

At the Heart of It All: Leadership in the Operating Room
Seminars in Thoracic and Cardiovascular Surgery. 2025; DOI:10.1053/J.SEMTCVS.2025.02.005.

Reply: Saving hearts: Utilizing cardiac catheterization after coronary artery bypass grafting
Journal of Thoracic and Cardiovascular Surgery. 2025; DOI:10.1016/J.JTCVS.2025.01.024.

2024

Adenosine 2A Receptor Agonism Improves Survival in Extracorporeal Cardiopulmonary Resuscitation
Journal of Surgical Research. 2024; 301: 404 - 412. DOI:10.1016/J.JSS.2024.06.033.

Appropriateness of Surgical Aortic Valve Replacement for Severe Aortic Stenosis is Increasing
The Annals of thoracic surgery. 2024; 117(2): 361 - 368. DOI:10.1016/J.ATHORACSUR.2022.07.036.

Association of tricuspid regurgitation with clinical events and quality of life after surgery for severe ischemic mitral regurgitation
JTCVS Structural and Endovascular. 2024; 1-2: 100003. DOI:10.1016/J.XJSE.2024.100003.

Machine Learning on 50,000 Manuscripts Shows Increased Clinical Research by Academic Cardiac Surgeons
Journal of Surgical Research. 2024; 303: 71 - 80. DOI:10.1016/J.JSS.2024.08.017.

Reply: The importance of early intervention for ischemia after coronary artery bypass grafting
Journal of Thoracic and Cardiovascular Surgery. 2024; 168(4): e102 - e103. DOI:10.1016/J.JTCVS.2023.10.037.

Rodent Model of Cardiopulmonary Bypass Demonstrates Systemic Inflammation and Neuromarker Changes
Journal of Surgical Research. 2024; 303: 780 - 787. DOI:10.1016/J.JSS.2024.09.041.

Targeted Antioxidant Therapy Reduces Hyperglycemic Exacerbation of Myocardial Ischemia/Reperfusion Injury
Journal of Surgical Research. 2024; 301: 554 - 562. DOI:10.1016/J.JSS.2024.06.023.

The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement
Journal of Thoracic and Cardiovascular Surgery. 2024; 167(2): 624 - 633.e4. DOI:10.1016/J.JTCVS.2022.01.053.

Transient receptor potential vanilloid 4 channel inhibition attenuates lung ischemia-reperfusion injury in a porcine lung transplant model
Journal of Thoracic and Cardiovascular Surgery. 2024; 168(4): e121 - e132. DOI:10.1016/J.JTCVS.2024.03.001.

Unplanned Postoperative Catheterization during Admission for Coronary Artery Bypass Grafting is neither Cheap nor Benign, but May Rescue Patients
Journal of Thoracic and Cardiovascular Surgery. 2024; 168(4): 1094 - 1106.e1. DOI:10.1016/J.JTCVS.2023.08.039.

2023

Barriers to atrial fibrillation ablation during mitral valve surgery
Journal of Thoracic and Cardiovascular Surgery. 2023; 165(2): 650 - 658.e1. DOI:10.1016/J.JTCVS.2021.03.039.

Effect of Cardiopulmonary Bypass on SARS‐CoV‐2 Vaccination Antibody Levels
Journal of the American Heart Association. 2023; 12(17):. DOI:10.1161/JAHA.123.029406.

Postdoctoral National Institutes of Health F32 Grants: Broken Pipeline in the Development of Surgeon Scientists
Annals of Surgery. 2023; DOI:10.1097/SLA.0000000000005956.

Socioeconomic Distress Associated With Increased Use of Percutaneous Coronary Intervention Over Coronary Artery Bypass Grafting
The Annals of thoracic surgery. 2023; 115(4): 914 - 921. DOI:10.1016/J.ATHORACSUR.2022.06.040.

Steen solution protects pulmonary microvascular endothelial cells and preserves endothelial barrier after lipopolysaccharide-induced injury
Journal of Thoracic and Cardiovascular Surgery. 2023; 165(1): e5 - e20. DOI:10.1016/J.JTCVS.2022.04.005.

2022

Commentary: Another layer to the “PPM conundrum”
Journal of Cardiac Surgery. 2022; 37(3): 628 - 629. DOI:10.1111/JOCS.16221.

Commentary: Extracardiac conduit‐total cavopulmonary connection for heterotaxy—Is going the “extra” mile worth it
Journal of Cardiac Surgery. 2022; 37(4): 948 - 949. DOI:10.1111/JOCS.16279.

Commentary: Long-term outcomes after internal thoracic artery grafting: Where does the time go?
JTCVS Open. 2022; 9: 114 - 115. DOI:10.1016/J.XJON.2022.01.011.

Commentary: Should we “keep rollin'” for PA/VSD/MAPCA?
Journal of Cardiac Surgery. 2022; 37(9): 2651 - 2652. DOI:10.1111/JOCS.16651.

Commentary: Small patients with big wounds
Journal of Cardiac Surgery. 2022; 37(11): 3703 - 3704. DOI:10.1111/JOCS.16845.

Commentary: The challenges of propensity score matching in cardiac surgery
Journal of Cardiac Surgery. 2022; 37(3): 588 - 589. DOI:10.1111/JOCS.16199.

Commentary: The Over and Under on Ischemic Mitral Regurgitation Repair
Journal of Thoracic and Cardiovascular Surgery. 2022; 164(3): 865 - 866. DOI:10.1016/J.JTCVS.2020.10.025.

Commentary: Thinking inside and outside of the box with intraextracardiac Fontan
Journal of Cardiac Surgery. 2022; 37(5): 1309 - 1310. DOI:10.1111/JOCS.16372.

Double chambered left ventricle—Two chambers are not better than one
Journal of Cardiac Surgery. 2022; 37(12): 5485 - 5486. DOI:10.1111/JOCS.16976.

Expanding our imagination with reanimation
Journal of Cardiac Surgery. 2022; 37(12): 5499 - 5500. DOI:10.1111/JOCS.17128.

Gastric Aspiration and Ventilator-Induced Model of Acute Respiratory Distress Syndrome in Swine
Journal of Surgical Research. 2022; 280: 280 - 287. DOI:10.1016/J.JSS.2022.07.023.

General principles of teaching cardiac surgery
Journal of Thoracic and Cardiovascular Surgery. 2022; 164(6): e487 - e490. DOI:10.1016/J.JTCVS.2022.07.023.

How to build and sustain an academic cardiothoracic surgery program
Journal of Thoracic and Cardiovascular Surgery. 2022; 163(4): 1431 - 1434. DOI:10.1016/J.JTCVS.2021.03.129.

Hydroxychloroquine Attenuates Myocardial Ischemic and Post-Ischemic Reperfusion Injury by Inhibiting the Toll-Like Receptor 9 – Type I Interferon Pathway
Cardiology and Cardiovascular Medicine. 2022; 06(04):. DOI:10.26502/FCCM.92920278.

National Institutes of Health Funding for Abdominal Organ Transplantation Research Has Declined: A 30-year Analysis
Transplantation. 2022; 106(10): 1909 - 1911. DOI:10.1097/TP.0000000000004082.

Secondary Burn Progression Mitigated by an Adenosine 2A Receptor Agonist
Journal of Burn Care and Research. 2022; 43(1): 133 - 140. DOI:10.1093/JBCR/IRAB053.

Suppression of Neuroinflammation Attenuates Persistent Cognitive and Neurogenic Deficits in a Rat Model of Cardiopulmonary Bypass
Frontiers in Cellular Neuroscience. 2022; 16:. DOI:10.3389/FNCEL.2022.780880.

Topical Neck Cooling Attenuates Inflammatory Responses and Sepsis Progression in Intra-abdominal Sepsis
Journal of the American College of Surgeons. 2022; 235(5): S302 - S302. DOI:10.1097/01.XCS.0000895380.20930.4A.

Topical Neck Cooling Without Systemic Hypothermia Attenuates Myocardial Ischemic Injury and Post-ischemic Reperfusion Injury
Frontiers in Cardiovascular Medicine. 2022; 9:. DOI:10.3389/FCVM.2022.893837.

Two Hours of In Vivo Lung Perfusion Improves Lung Function in Sepsis-Induced Acute Respiratory Distress Syndrome
Seminars in Thoracic and Cardiovascular Surgery. 2022; 34(1): 337 - 346. DOI:10.1053/J.SEMTCVS.2021.02.034.

2021

A 30-year analysis of National Institutes of Health–funded cardiac transplantation research: Surgeons lead the way
Journal of Thoracic and Cardiovascular Surgery. 2021; 162(6): 1757 - 1765.e1. DOI:10.1016/J.JTCVS.2020.06.076.

Abstract 9769: Bicarbonate Treatment Before Reperfusion Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibition of Spleen-Mediated Inflammatory Response
Circulation. 2021; 144(Suppl_1):. DOI:10.1161/CIRC.144.SUPPL_1.9769.

Buy-In, Get More: Protocols to Increase Multi-Arterial Grafting Use
Journal of the American College of Surgeons. 2021; 232(6): 961 - 962. DOI:10.1016/J.JAMCOLLSURG.2021.02.007.

Commentary: Cardiothoracic surgery training made SIMPL
Journal of Cardiac Surgery. 2021; 36(12): 4688 - 4689. DOI:10.1111/JOCS.16023.

Commentary: Correlation of coronary and valve procedure outcomes between centers
Journal of Cardiac Surgery. 2021; 36(2): 659 - 660. DOI:10.1111/JOCS.15241.

Commentary: Getting in the zone: Thoracic endovascular aortic repair safety in Ishimaru zones 0 and 1
JTCVS Techniques. 2021; 7: 7 - 8. DOI:10.1016/J.XJTC.2021.02.001.

Commentary: Litigation risk in congenital cardiac surgery
Journal of Cardiac Surgery. 2021; 36(1): 143 - 144. DOI:10.1111/JOCS.15110.

Commentary: Malpractice in heart transplantation
Journal of Cardiac Surgery. 2021; 36(8): 2791 - 2792. DOI:10.1111/JOCS.15664.

Commentary: Planes, trains, and automobiles—Effective use of prolonged ex vivo heart preservation
Journal of Cardiac Surgery. 2021; 36(7): 2596 - 2597. DOI:10.1111/JOCS.15520.

Commentary: Predictors of postoperative adverse events after cone reconstruction for Ebstein's anomaly
Journal of Cardiac Surgery. 2021; 36(3): 1018 - 1019. DOI:10.1111/JOCS.15376.

Commentary: When will the robots come marching in?
Journal of Cardiac Surgery. 2021; 36(9): 3193 - 3194. DOI:10.1111/JOCS.15715.

Effect of Cardiac Surgery on One-Year Patient-Reported Outcomes: A Prospective Cohort Study
The Annals of thoracic surgery. 2021; 112(5): 1410 - 1416. DOI:10.1016/J.ATHORACSUR.2020.09.061.

Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research
Scientific Reports. 2021; 11(1):. DOI:10.1038/S41598-021-92143-W.

Meaningful Patient-centered Outcomes 1 Year Following Cardiac Surgery
Annals of Surgery. 2021; 273(6): e247 - e254. DOI:10.1097/SLA.0000000000003357.

Mixed type TAPVR—Measure twice, cut once
Journal of Cardiac Surgery. 2021; 36(8): 2954 - 2955. DOI:10.1111/JOCS.15632.

Plasmacytoid Dendritic Cells Mediate Myocardial Ischemia/Reperfusion Injury by Secreting Type I Interferons
Journal of the American Heart Association. 2021; 10(15):. DOI:10.1161/JAHA.121.020754.

Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation
Journal of the American College of Cardiology. 2021; 77(6): 713 - 724. DOI:10.1016/J.JACC.2020.11.066.

Pulsed ultrasound attenuates the hyperglycemic exacerbation of myocardial ischemia–reperfusion injury
Journal of Thoracic and Cardiovascular Surgery. 2021; 161(4): e297 - e306. DOI:10.1016/J.JTCVS.2019.10.096.

REPLY: CONCOMITANT AORTIC REPLACEMENT: HOW PROACTIVE SHOULD WE BE?
Journal of Thoracic and Cardiovascular Surgery. 2021; 161(2): e152 - e153. DOI:10.1016/J.JTCVS.2020.07.108.

Reply: Subvalvular Repair for Ischemic Mitral Regurgitation: Setting up the Endgame
JTCVS Open. 2021; 8: 294 - 295. DOI:10.1016/J.XJON.2021.07.019.

Risk for non-home discharge following surgery for ischemic mitral valve disease
Journal of Thoracic and Cardiovascular Surgery. 2021; 162(6): 1769 - 1778.e7. DOI:10.1016/J.JTCVS.2020.02.084.

TEN YEAR MEDICARE TRENDS IN MITRAL VALVE PROCEDURES: CONTEMPORARY MANAGEMENT AND OUTCOMES
Journal of the American College of Cardiology. 2021; 77(18): 1742. DOI:10.1016/S0735-1097(21)03098-9.

Topical Neck Cooling Prolongs Survival of Rats with Intra-Abdominal Feculent Sepsis by Activation of the Vagus Nerve
International Journal of Molecular Sciences. 2021; 22(18): 9828. DOI:10.3390/IJMS22189828.

Variability and Utilization of Concomitant Atrial Fibrillation Ablation During Mitral Valve Surgery
The Annals of thoracic surgery. 2021; 111(1): 29 - 34. DOI:10.1016/J.ATHORACSUR.2020.05.125.

2020

Adenosine A2A receptor agonist (regadenoson) in human lung transplantation
The Journal of Heart and Lung Transplantation. 2020; 39(6): 563 - 570. DOI:10.1016/J.HEALUN.2020.02.003.

Commentary: Cervical aortic arch repair—an overarching success
Journal of Thoracic and Cardiovascular Surgery. 2020; 159(6): 2214 - 2215. DOI:10.1016/J.JTCVS.2019.03.086.

Commentary: Do Not Fear The Ascending Aorta
Journal of Thoracic and Cardiovascular Surgery. 2020; 159(5): 1681 - 1682. DOI:10.1016/J.JTCVS.2019.05.055.

Commentary: Superior Vena Cava Reconstruction Techniques
JTCVS Techniques. 2020; 4: 187 - 188. DOI:10.1016/J.XJTC.2020.10.040.

Comprehensive National Institutes of Health funding analysis of academic cardiac surgeons
Journal of Thoracic and Cardiovascular Surgery. 2020; 159(6): 2326 - 2335.e3. DOI:10.1016/J.JTCVS.2019.08.032.

Cost-effectiveness of coronary artery bypass grafting plus mitral valve repair versus coronary artery bypass grafting alone for moderate ischemic mitral regurgitation
Journal of Thoracic and Cardiovascular Surgery. 2020; 159(6): 2230 - 2240.e15. DOI:10.1016/J.JTCVS.2019.06.040.

Gastrointestinal Complications After Cardiac Surgery: Highly Morbid but Improving Over Time
Journal of Surgical Research. 2020; 254: 306 - 313. DOI:10.1016/J.JSS.2020.02.019.

Goal-directed resuscitation following cardiac surgery reduces acute kidney injury: A quality initiative pre–post analysis
Journal of Thoracic and Cardiovascular Surgery. 2020; 159(5): 1868 - 1877.e1. DOI:10.1016/J.JTCVS.2019.03.135.

Impact of Complications After Cardiac Operation on One-Year Patient-Reported Outcomes
The Annals of thoracic surgery. 2020; 109(1): 43 - 48. DOI:10.1016/J.ATHORACSUR.2019.05.067.

Inhibition of Toll-Like Receptor 9 Attenuates Myocardial Ischemia-Reperfusion Injury
Journal of the American College of Surgeons. 2020; 231(4): S49. DOI:10.1016/J.JAMCOLLSURG.2020.07.075.

Isolated Lung Perfusion in the Management of Acute Respiratory Distress Syndrome
International Journal of Molecular Sciences. 2020; 21(18): 6820. DOI:10.3390/IJMS21186820.

Mortality After Repeat Revascularization Following PCI or CABG for Left Main Disease
JACC: Cardiovascular Interventions. 2020; 13(3): 375 - 387. DOI:10.1016/J.JCIN.2019.09.019.

Persistent cognitive deficits and neuroinflammation in a rat model of cardiopulmonary bypass
Journal of Thoracic and Cardiovascular Surgery. 2020; 160(4): e185 - e188. DOI:10.1016/J.JTCVS.2019.12.070.

Reduced-flow ex vivo lung perfusion to rehabilitate lungs donated after circulatory death
The Journal of Heart and Lung Transplantation. 2020; 39(1): 74 - 82. DOI:10.1016/J.HEALUN.2019.09.009.

Risk Aversion in Cardiac Surgery: 15-Year Trends in a Statewide Analysis
The Annals of thoracic surgery. 2020; 109(5): 1401 - 1407. DOI:10.1016/J.ATHORACSUR.2019.08.027.

SPECT imaging of lung ischemia-reperfusion injury using [ 99m Tc]cFLFLF for molecular targeting of formyl peptide receptor 1
American Journal of Physiology - Lung Cellular and Molecular Physiology. 2020; 318(2): L304 - L313. DOI:10.1152/AJPLUNG.00220.2018.

Stopping the Burn: Adenosine 2A Receptor Agonist Attenuates Burn Progression in a Porcine Model
Journal of the American College of Surgeons. 2020; 231(4): S331. DOI:10.1016/J.JAMCOLLSURG.2020.07.682.

2019

A focused approach: Specialization in coronary revascularization
Journal of Thoracic and Cardiovascular Surgery. 2019; 157(3): 948 - 949. DOI:10.1016/J.JTCVS.2018.09.004.

Acute Hyperglycemia Exacerbates Myocardial Ischemia/Reperfusion Injury by Activating an FPR1-HMS-NADPH Oxidase Pathway
Journal of the American College of Surgeons. 2019; 229(4): S43. DOI:10.1016/J.JAMCOLLSURG.2019.08.107.

Adenosine 2A Receptor Activation Attenuates Ischemia Reperfusion Injury During Extracorporeal Cardiopulmonary Resuscitation
Annals of Surgery. 2019; 269(6): 1176 - 1183. DOI:10.1097/SLA.0000000000002685.

Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points
Journal of Thoracic and Cardiovascular Surgery. 2019; 157(1): 234 - 243.e9. DOI:10.1016/J.JTCVS.2018.06.093.

Can Lung Transplant Surgeons Still Be Scientists? High Productivity Despite Competitive Funding
The Heart Surgery Forum. 2019; 22(1): E001 - E007. DOI:10.1532/HSF.2024.

Development and Validation of Procedure-Specific Risk Score for Predicting Postoperative Pulmonary Complication: A NSQIP Analysis
Journal of the American College of Surgeons. 2019; 229(4): 355 - 365e3. DOI:10.1016/J.JAMCOLLSURG.2019.05.028.

One-Year Outcomes After MitraClip for Functional Mitral Regurgitation
Circulation. 2019; 139(1): 37 - 47. DOI:10.1161/CIRCULATIONAHA.117.031733.

Outcomes of left main revascularization in patients with acute coronary syndromes and stable ischemic heart disease: Analysis from the EXCEL trial
American Heart Journal. 2019; 214: 9 - 17. DOI:10.1016/J.AHJ.2019.04.016.

Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation
Journal of the American College of Cardiology. 2019; 73(19): 2427 - 2435. DOI:10.1016/J.JACC.2019.02.062.

Preoperative β-blocker use correlates with worse outcomes in patients undergoing aortic valve replacement
Journal of Thoracic and Cardiovascular Surgery. 2019; 158(6): 1589 - 1597.e3. DOI:10.1016/J.JTCVS.2018.12.108.

Socioeconomic Distressed Communities Index Predicts Risk-Adjusted Mortality After Cardiac Surgery
The Annals of thoracic surgery. 2019; 107(6): 1706 - 1712. DOI:10.1016/J.ATHORACSUR.2018.12.022.

TCT-307 Vascular Closure Device Use After PCI for Left Main Disease: Analysis From the EXCEL Trial
Journal of the American College of Cardiology. 2019; 74(13): B305. DOI:10.1016/J.JACC.2019.08.384.

The myocardial infarct-exacerbating effect of cell-free DNA is mediated by the high-mobility group box 1–receptor for advanced glycation end products–Toll-like receptor 9 pathway
Journal of Thoracic and Cardiovascular Surgery. 2019; 157(6): 2256 - 2269.e3. DOI:10.1016/J.JTCVS.2018.09.043.

Travel distance and regional access to cardiac valve surgery
Journal of Cardiac Surgery. 2019; 34(10): 1044 - 1048. DOI:10.1111/JOCS.14199.

2018

“See one, do one, teach one”: It is still possible in cardiothoracic surgical education
Journal of Thoracic and Cardiovascular Surgery. 2018; 156(2): 716 - 717. DOI:10.1016/J.JTCVS.2018.04.042.

A Comparison of Outcomes after Lower Extremity Bypass and Repeat Endovascular Intervention following Failed Previous Endovascular Intervention for Critical Limb Ischemia
Annals of Vascular Surgery. 2018; 48: 24. DOI:10.1016/J.AVSG.2018.01.042.

Amiodarone Protocol Provides Cost-Effective Reduction in Postoperative Atrial Fibrillation
The Annals of thoracic surgery. 2018; 105(6): 1697 - 1702. DOI:10.1016/J.ATHORACSUR.2017.12.029.

Bedside-to-Bench and Back Again: Surgeon-Initiated Translational Research
The Annals of thoracic surgery. 2018; 105(1): 10 - 11. DOI:10.1016/J.ATHORACSUR.2017.06.026.

Cardiothoracic and Vascular Surgeons Achieve High Rates of K Award Conversion Into R01 Funding
The Annals of thoracic surgery. 2018; 106(2): 602 - 607. DOI:10.1016/J.ATHORACSUR.2018.02.029.

Cardiothoracic Surgery Training Grants Provide Protected Research Time Vital to the Development of Academic Surgeons
Journal of Thoracic and Cardiovascular Surgery. 2018; 155(5): 2050 - 2056. DOI:10.1016/J.JTCVS.2017.12.041.

Contemporary outcomes in reoperative mitral valve surgery
Heart. 2018; 104(8): 652 - 656. DOI:10.1136/HEARTJNL-2017-312047.

Coronary artery bypass grafting bundled payment proposal will have significant financial impact on hospitals
Journal of Thoracic and Cardiovascular Surgery. 2018; 155(1): 182 - 188. DOI:10.1016/J.JTCVS.2017.07.035.

Cost of individual complications following coronary artery bypass grafting
Journal of Thoracic and Cardiovascular Surgery. 2018; 155(3): 875 - 882.e1. DOI:10.1016/J.JTCVS.2017.08.144.

Cost-Effectiveness of Mitral Valve Repair Versus Replacement for Severe Ischemic Mitral Regurgitation: A Randomized Clinical Trial From the Cardiothoracic Surgical Trials Network
Circulation - Cardiovascular Quality and Outcomes. 2018; 11(11):. DOI:10.1161/CIRCOUTCOMES.117.004466.

Development of a Risk Prediction Model and Clinical Risk Score for Isolated Tricuspid Valve Surgery
The Annals of thoracic surgery. 2018; 106(1): 129 - 136. DOI:10.1016/J.ATHORACSUR.2017.11.077.

Does Preoperative Troponin Level Impact Outcomes After Coronary Artery Bypass Grafting?
The Annals of thoracic surgery. 2018; 106(1): 46 - 51. DOI:10.1016/J.ATHORACSUR.2018.01.085.

Ex Vivo Assessment of Porcine Donation After Circulatory Death Lungs That Undergo Increasing Warm Ischemia Times
Transplantation Direct. 2018; 4(12): e405. DOI:10.1097/TXD.0000000000000845.

Expanding the donor lung pool: how many donation after circulatory death organs are we missing?
Journal of Surgical Research. 2018; 223: 58 - 63. DOI:10.1016/J.JSS.2017.09.029.

Implementing a Computer-Based Glucose Management Protocol Improves Outcomes and Value in Cardiac Surgery
Journal of the American College of Surgeons. 2018; 227(4): S48. DOI:10.1016/J.JAMCOLLSURG.2018.07.084.

In vivo lung perfusion rehabilitates sepsis-induced lung injury
Journal of Thoracic and Cardiovascular Surgery. 2018; 155(1): 440 - 448.e2. DOI:10.1016/J.JTCVS.2017.08.124.

Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion
Journal of Thoracic and Cardiovascular Surgery. 2018; 156(2): 910 - 917. DOI:10.1016/J.JTCVS.2018.02.090.

Infarct-sparing effect of adenosine A2B receptor agonist is primarily due to its action on splenic leukocytes via a PI3K/Akt/IL-10 pathway
Journal of Surgical Research. 2018; 232: 442 - 449. DOI:10.1016/J.JSS.2018.06.042.

Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease
Journal of the American College of Cardiology. 2018; 72(7): 754 - 765. DOI:10.1016/J.JACC.2018.05.057.

Level 1 evidence remains elusive in asymptomatic severe organic mitral valve regurgitation
Structural Heart. 2018; 2(5): 386 - 387. DOI:10.1080/24748706.2018.1493246.

Loss of Medicaid insurance after successful bariatric surgery: an unintended outcome
Surgical Endoscopy. 2018; 32(1): 212 - 216. DOI:10.1007/S00464-017-5661-3.

Major adverse limb events and major adverse cardiac events after contemporary lower extremity bypass and infrainguinal endovascular intervention in patients with claudication
Journal of Vascular Surgery. 2018; 68(6): 1817 - 1823. DOI:10.1016/J.JVS.2018.06.193.

Minimally invasive mitral valve surgery is associated with excellent resource utilization, cost, and outcomes
Journal of Thoracic and Cardiovascular Surgery. 2018; 156(2): 611 - 616.e3. DOI:10.1016/J.JTCVS.2018.03.108.

National Utilization and Outcomes of Redo Lower Extremity Bypass versus Endovascular Intervention after a Previous Failed Bypass
Annals of Vascular Surgery. 2018; 47: 18 - 23. DOI:10.1016/J.AVSG.2017.08.033.

Need for Permanent Pacemaker after Surgical Aortic Valve Replacement Reduces Long-Term Survival
The Annals of thoracic surgery. 2018; 106(2): 460 - 465. DOI:10.1016/J.ATHORACSUR.2018.02.041.

One-Year Patient-Reported Outcomes Define True Quality after Cardiac Surgery
Journal of the American College of Surgeons. 2018; 227(4): S51 - S52. DOI:10.1016/J.JAMCOLLSURG.2018.07.092.

Pannexin-1 channels on endothelial cells mediate vascular inflammation during lung ischemia-reperfusion injury
American Journal of Physiology - Lung Cellular and Molecular Physiology. 2018; 315(2): L301 - L312. DOI:10.1152/AJPLUNG.00004.2018.

Preoperative anemia versus blood transfusion: Which is the culprit for worse outcomes in cardiac surgery?
Journal of Thoracic and Cardiovascular Surgery. 2018; 156(1): 66 - 74.e2. DOI:10.1016/J.JTCVS.2018.03.109.

Remote Ischemic Preconditioning: a Complex Question with an Even More Complex Answer
Seminars in Thoracic and Cardiovascular Surgery. 2018; 30(1): 34 - 35. DOI:10.1053/J.SEMTCVS.2018.02.020.

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study
Journal of Thoracic and Cardiovascular Surgery. 2018; 155(4): 1555 - 1562.e1. DOI:10.1016/J.JTCVS.2017.10.078.

Stimulation of the Beta2 Adrenergic Receptor at Reperfusion Limits Myocardial Reperfusion Injury via an Interleukin-10-Dependent Anti-Inflammatory Pathway in the Spleen
Circulation Journal. 2018; 82(11): 2829 - 2836. DOI:10.1253/CIRCJ.CJ-18-0061.

Surgeon Scientists Are Disproportionately Affected by Declining NIH Funding Rates
Journal of the American College of Surgeons. 2018; 226(4): 474 - 481. DOI:10.1016/J.JAMCOLLSURG.2017.12.047.

The rest of the story: long-term, patient-reported outcomes in cardiac surgery
Journal of Thoracic and Cardiovascular Surgery. 2018; 156(6): 2191. DOI:10.1016/J.JTCVS.2018.05.093.

Travel Time Does Not Adversely Effect Outcomes After Ventricular Assist Device
The Journal of Heart and Lung Transplantation. 2018; 37(4): S270. DOI:10.1016/J.HEALUN.2018.01.675.

2017

2016 update to The American Association for Thoracic Surgery (AATS) consensus guidelines: Ischemic mitral valve regurgitation
Journal of Thoracic and Cardiovascular Surgery. 2017; 153(5): e97 - e114. DOI:10.1016/J.JTCVS.2017.01.031.

2016 update to The American Association for Thoracic Surgery consensus guidelines: Ischemic mitral valve regurgitation
Journal of Thoracic and Cardiovascular Surgery. 2017; 153(5): 1076 - 1079. DOI:10.1016/J.JTCVS.2016.11.068.

A New Intraoperative Protocol for Reducing Perioperative Transfusions in Cardiac Surgery
The Annals of thoracic surgery. 2017; 104(1): 176 - 181. DOI:10.1016/J.ATHORACSUR.2016.10.032.

Access to Quaternary Care Surgery: Implications for Accountable Care Organizations
Journal of the American College of Surgeons. 2017; 224(4): 525 - 529. DOI:10.1016/J.JAMCOLLSURG.2016.12.017.

Airway pressure release ventilation during ex vivo lung perfusion attenuates injury
Journal of Thoracic and Cardiovascular Surgery. 2017; 153(1): 197 - 204. DOI:10.1016/J.JTCVS.2016.09.029.

Data, not dogma, for ischemic mitral regurgitation
Journal of Thoracic and Cardiovascular Surgery. 2017; 154(1): 137 - 138. DOI:10.1016/J.JTCVS.2017.03.101.

Decubitus ulcers in patients undergoing vascular operations do not influence mortality but affect resource utilization
Surgery. 2017; 161(6): 1720 - 1727. DOI:10.1016/J.SURG.2017.02.002.

Does Preoperative Troponin Level Impact Outcomes after Coronary Artery Bypass Grafting?
Journal of the American College of Surgeons. 2017; 225(4): S28 - S29. DOI:10.1016/J.JAMCOLLSURG.2017.07.043.

Ex Vivo Lung Perfusion Rehabilitates Sepsis-Induced Lung Injury
The Annals of thoracic surgery. 2017; 103(6): 1723 - 1729. DOI:10.1016/J.ATHORACSUR.2017.01.018.

Impact of Medicaid Expansion on Cardiac Surgery Volume and Outcomes
The Annals of thoracic surgery. 2017; 104(4): 1251 - 1258. DOI:10.1016/J.ATHORACSUR.2017.03.079.

Improved outcomes and value in staged hybrid extent II thoracoabdominal aortic aneurysm repair
Journal of Vascular Surgery. 2017; 66(5): 1357 - 1363. DOI:10.1016/J.JVS.2017.03.420.

Improving Outcomes and Value with Staged Hybrid Extent II Thoracoabdominal Aortic Aneurysm Repair
Journal of Vascular Surgery. 2017; 65(1): e12. DOI:10.1016/J.JVS.2016.10.030.

Lower extremity bypass for critical limb ischemia decreases major adverse limb events with equivalent cardiac risk compared with endovascular intervention
Journal of Vascular Surgery. 2017; 66(4): 1109 - 1116.e1. DOI:10.1016/J.JVS.2017.04.036.

Lower Extremity Bypass Is Associated with Lower Short-Term Major Adverse Limb Events and Equivalent Major Adverse Cardiac Events Compared with Endovascular Intervention in A National Cohort with Critical Limb Ischemia
Journal of Vascular Surgery. 2017; 65(1): e4 - e5. DOI:10.1016/J.JVS.2016.10.018.

Lungs donated after circulatory death and prolonged warm ischemia are transplanted successfully after enhanced ex vivo lung perfusion using adenosine A2B receptor antagonism
Journal of Thoracic and Cardiovascular Surgery. 2017; 154(5): 1811 - 1820. DOI:10.1016/J.JTCVS.2017.02.072.

Management of Ebstein’s anomaly
Annals of Cardiothoracic Surgery. 2017; 6(3): 266 - 269. DOI:10.21037/ACS.2017.05.03.

Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death
Respiratory Research. 2017; 18(1):. DOI:10.1186/S12931-017-0704-9.

Methylene Blue for Vasoplegic Syndrome After Cardiac Operation: Early Administration Improves Survival
The Annals of thoracic surgery. 2017; 104(1): 36 - 41. DOI:10.1016/J.ATHORACSUR.2017.02.057.

Mitral Valve Repair
Surgical Clinics. 2017; 97(4): 867 - 888. DOI:10.1016/J.SUC.2017.03.009.

Modifiable Factors Leading to Increased Length of Stay after Carotid Endarterectomy
Annals of Vascular Surgery. 2017; 39: 195 - 203. DOI:10.1016/J.AVSG.2016.05.126.

Obesity Increases Risk‐Adjusted Morbidity, Mortality, and Cost Following Cardiac Surgery
Journal of the American Heart Association. 2017; 6(3):. DOI:10.1161/JAHA.116.003831.

Outcomes of Trainees Performing Coronary Artery Bypass Grafting: Does Resident Experience Matter?
The Annals of thoracic surgery. 2017; 103(3): 975 - 981. DOI:10.1016/J.ATHORACSUR.2016.10.016.

Postoperative Hypoglycemia Is Associated With Worse Outcomes After Cardiac Operations
The Annals of thoracic surgery. 2017; 103(2): 526 - 532. DOI:10.1016/J.ATHORACSUR.2016.05.121.

Predicting recurrent mitral regurgitation after mitral valve repair: A difficult endeavor and a necessity
Journal of Thoracic and Cardiovascular Surgery. 2017; 153(1): 145 - 146. DOI:10.1016/J.JTCVS.2016.09.054.

Pre-Implant Left Ventricular Apex Position Predicts Risk of HeartMate II Pump Thrombosis
The Journal of Heart and Lung Transplantation. 2017; 36(4): S29. DOI:10.1016/J.HEALUN.2017.01.063.

Pre-implant left ventricular apex position predicts risk of HeartMate II pump thrombosis
Journal of Cardiac Surgery. 2017; 32(12): 837 - 842. DOI:10.1111/JOCS.13382.

Repairing the Mitral Subvalvular Apparatus: The New Frontier
Journal of Thoracic and Cardiovascular Surgery. 2017; 153(2): 284 - 285. DOI:10.1016/J.JTCVS.2016.09.073.

Response by Capoulade et al to Letter Regarding Article, “Impact of Left Ventricular to Mitral Valve Ring Mismatch on Recurrent Ischemic Mitral Regurgitation After Ring Annuloplasty”
Circulation. 2017; 135(12):. DOI:10.1161/CIRCULATIONAHA.117.026957.

Sphingosine-1-Phosphate Attenuates Lung Injury in Murine Model of Ex Vivo Lung Perfusion
The Journal of Heart and Lung Transplantation. 2017; 36(4): S91. DOI:10.1016/J.HEALUN.2017.01.230.

Surgeon, not institution, case volume is associated with limb outcomes after lower extremity bypass for critical limb ischemia in the Vascular Quality Initiative
Journal of Vascular Surgery. 2017; 66(5): 1457 - 1463. DOI:10.1016/J.JVS.2017.03.434.

Which ischemic mitral valves should be repaired and how? Time will tell
Journal of Thoracic and Cardiovascular Surgery. 2017; 154(3): 833. DOI:10.1016/J.JTCVS.2017.05.006.

2016

2015 The American Association for Thoracic Surgery Consensus Guidelines: Ischemic mitral valve regurgitation
Journal of Thoracic and Cardiovascular Surgery. 2016; 151(4): 940 - 956. DOI:10.1016/J.JTCVS.2015.08.127.

Attenuation of Pulmonary Ischemia-Reperfusion Injury by Adenosine A 2B Receptor Antagonism
The Annals of thoracic surgery. 2016; 102(2): 385 - 393. DOI:10.1016/J.ATHORACSUR.2016.02.060.

Cardiothoracic Surgical Trials Network: Evidence-based surgery
Journal of Thoracic and Cardiovascular Surgery. 2016; 151(1): 28 - 29. DOI:10.1016/J.JTCVS.2015.09.122.

Donation After Circulatory Death Lungs Transplantable Up to Six Hours After Ex Vivo Lung Perfusion
The Annals of thoracic surgery. 2016; 102(6): 1845 - 1853. DOI:10.1016/J.ATHORACSUR.2016.06.043.

Ex vivo lung perfusion with adenosine A2A receptor agonist allows prolonged cold preservation of lungs donated after cardiac death
Journal of Thoracic and Cardiovascular Surgery. 2016; 151(2): 538 - 546. DOI:10.1016/J.JTCVS.2015.07.075.

How I Teach Mitral Valve Surgery
The Annals of thoracic surgery. 2016; 101(5): 1641 - 1643. DOI:10.1016/J.ATHORACSUR.2016.03.029.

How much is enough to warrant prophylactic tricuspid repair?
Journal of Thoracic and Cardiovascular Surgery. 2016; 151(3): 796 - 797. DOI:10.1016/J.JTCVS.2015.11.003.

Impact of Left Ventricular to Mitral Valve Ring Mismatch on Recurrent Ischemic Mitral Regurgitation After Ring Annuloplasty
Circulation. 2016; 134(17): 1247 - 1256. DOI:10.1161/CIRCULATIONAHA.115.021014.

Introducing the “How I Teach It” Editorial Series
The Annals of thoracic surgery. 2016; 101(1): 11. DOI:10.1016/J.ATHORACSUR.2015.10.068.

Low Risk TAVR: The Long View
The Annals of thoracic surgery. 2016; 102(2): 357. DOI:10.1016/J.ATHORACSUR.2016.04.032.

Mind the Gaps: Comparing Vascular Quality Initiative and National Surgical Quality Improvement Program Populations and Outcomes in Open Infrainguinal Bypass
Journal of Vascular Surgery. 2016; 63(1): 289 - 290. DOI:10.1016/J.JVS.2015.10.039.

Minimally Invasive Mitral Valve Surgery Provides Excellent Outcomes Without Increased Cost: A Multi-Institutional Analysis
The Annals of thoracic surgery. 2016; 102(1): 14 - 21. DOI:10.1016/J.ATHORACSUR.2016.01.084.

Natural history of coexistent mitral regurgitation after aortic valve replacement
Journal of Thoracic and Cardiovascular Surgery. 2016; 151(4): 1032 - 1042.e1. DOI:10.1016/J.JTCVS.2015.12.006.

NOX2 Activation of Natural Killer T Cells Is Blocked by the Adenosine A 2A Receptor to Inhibit Lung Ischemia–Reperfusion Injury
American Journal of Respiratory and Critical Care Medicine. 2016; 193(9): 988 - 999. DOI:10.1164/RCCM.201506-1253OC.

Patient-prosthesis mismatch: surgical aortic valve replacement versus transcatheter aortic valve replacement in high risk patients with aortic stenosis
Journal of Thoracic Disease. 2016; 8(10): E1441 - E1443. DOI:10.21037/JTD.2016.09.62.

Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose‐Alpha‐1,3‐Galactose
Journal of Cardiac Surgery. 2016; 31(7): 446 - 448. DOI:10.1111/JOCS.12764.

Rapamycin prevents bronchiolitis obliterans through increasing infiltration of regulatory B cells in a murine tracheal transplantation model
Journal of Thoracic and Cardiovascular Surgery. 2016; 151(2): 487 - 496.e3. DOI:10.1016/J.JTCVS.2015.08.116.

Surgeon, Not Institution, Case Volume Is Associated With Limb Outcomes After Lower Extremity Bypass for Critical Limb Ischemia in the Vascular Quality Initiative
Journal of Vascular Surgery. 2016; 64(3): 843 - 844. DOI:10.1016/J.JVS.2016.06.033.

Surgical Unroofing for Anomalous Aortic Origin of Coronary Arteries
Operative Techniques in Thoracic and Cardiovascular Surgery. 2016; 21(3): 162 - 177. DOI:10.1053/J.OPTECHSTCVS.2017.07.001.

The History of Incidentally Discovered Penetrating Aortic Ulcers of the Abdominal Aorta
Annals of Vascular Surgery. 2016; 31: 8 - 17. DOI:10.1016/J.AVSG.2015.08.028.

The natural history of penetrating ulcers of the iliac arteries
Journal of Vascular Surgery. 2016; 63(2): 399 - 406. DOI:10.1016/J.JVS.2015.08.097.

The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE
Basic Research in Cardiology. 2016; 111(6):. DOI:10.1007/S00395-016-0583-0.

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation
New England Journal of Medicine. 2016; 374(4): 344 - 353. DOI:10.1056/NEJMOA1512913.

Vascular Quality Initiative and National Surgical Quality Improvement Program registries capture different populations and outcomes in open infrainguinal bypass
Journal of Vascular Surgery. 2016; 64(3): 629 - 637. DOI:10.1016/J.JVS.2016.03.455.