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Imre Noth

Imre Noth

Professor, Medicine- Pulmonary and Critical Care Medicine

Bio & Overview

Academic Information

Department
Medicine- Pulmonary and Critical Care Medicine

Primary Education

  • MD, Medicine, University of Arizona, 1992

Research Interests

Idiopathic pulmonary fibrosis genetics, genomics and clinical trials

Selected Publications

2024

Carter, H., Costa, R. M., Adams, T. S., Gilchrist, T., Emch, C. E., Bame, M., . . . Gurczynski, S. J. (2024). Dendritic Cell - Fibroblast Crosstalk via TLR9 and AHR Signaling Drives Lung Fibrogenesis.. bioRxiv. doi:10.1101/2024.03.15.584457

Raghu, G., Ghazipura, M., Fleming, T. R., Aronson, K. I., Behr, J., Brown, K. K., . . . Martinez, F. J. (2024). Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Emphasis on 'Feels, Functions, Survives' Report of a Collaborative Discussion in a Symposium with Direct Engagement from Representatives of Patients, Investigators, the National Institutes of Health, a Patient Advocacy Organization, and a Regulatory Agency. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 209(6), 647-669. doi:10.1164/rccm.202312-2213SO

2023

Kim, J. S., Montesi, S. B., Adegunsoye, A., Humphries, S. M., Salisbury, M. L., Hariri, L. P., . . . Podolanczuk, A. J. (2023). Approach to Clinical Trials for the Prevention of Pulmonary Fibrosis. ANNALS OF THE AMERICAN THORACIC SOCIETY, 20(12), 1683-1693. doi:10.1513/AnnalsATS.202303-188PS

Kim, J. S., Murray, S., Yow, E., Anstrom, K. J., Kim, H. J., Flaherty, K. R., . . . Noth, I. (2024). Comparison of Pirfenidone and Nintedanib Post Hoc Analysis of the CleanUP-IPF Study. CHEST, 165(5), 1163-1173. doi:10.1016/j.chest.2023.11.035

Zhang, D., Adegunsoye, A., Oldham, J. M., Kozlitina, J., Garcia, N., Poonawalla, M., . . . Newton, C. A. (2023). Telomere length and immunosuppression in non-idiopathic pulmonary fibrosis interstitial lung disease. EUROPEAN RESPIRATORY JOURNAL, 62(5). doi:10.1183/13993003.00441-2023

Kim, J. S., Ma, S. -F., Ma, J. Z., Huang, Y., Bonham, C. A., Oldham, J. M., . . . Noth, I. (2024). Associations of Plasma Omega-3 Fatty Acids With Progression and Survival in Pulmonary Fibrosis. CHEST, 165(3), 621-631. doi:10.1016/j.chest.2023.09.035

Davis, C. L., Bjoring, M., Hursh, J., Smith, S., Blevins, C., Blackstone, K., . . . Enfield, K. (2023). The Intensive Care Unit Bundle Board: A Novel Real-Time Data Visualization Tool to Improve Maintenance Care for Invasive Catheters. APPLIED CLINICAL INFORMATICS, 14(05), 892-902. doi:10.1055/a-2165-5861

Oldham, J. M., Allen, R. J., Lorenzo-Salazar, J. M., Flores, C., Wain, L. V., & Noth, I. (2023). PCSK6: The Endogenous PAR-1 Agonist Driving Pulmonary Fibrosis? Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207(12), 1644-1645. doi:10.1164/rccm.202303-0402LE

Oldham, J. M., Allen, R. J., Lorenzo-Salazar, J. M., Molyneaux, P. L., Ma, S. -F., Joseph, C., . . . Noth, I. (2023). PCSK6 and Survival in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207(11), 1515-1524. doi:10.1164/rccm.202205-0845OC

Ruan, P., Todd, J. L., Zhao, H., Liu, Y., Vinisko, R., Soellner, J. F., . . . Salisbury, M. L. (2023). Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression. RESPIRATORY RESEARCH, 24(1). doi:10.1186/s12931-023-02435-0

Reynolds, C. J., Del Greco, F., Allen, R. J., Flores, C., Jenkins, R. G., Maher, T. M., . . . Minelli, C. (2023). The causal relationship between gastro-oesophageal reflux disease and idiopathic pulmonary fibrosis: a bidirectional two-sample Mendelian randomisation study. EUROPEAN RESPIRATORY JOURNAL, 61(5). doi:10.1183/13993003.01585-2022

Peljto, A. L., Blumhagen, R. Z., Walts, A. D., Cardwell, J., Powers, J., Corte, T. J., . . . Schwartz, D. A. (2023). Idiopathic Pulmonary Fibrosis Is Associated with Common Genetic Variants and Limited Rare Variants. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207(9), 1194-1202. doi:10.1164/rccm.202207-1331OC

Adegunsoye, A., Newton, C. A., Oldham, J. M., Ley, B., Lee, C. T., Linderholm, A. L., . . . Noth, I. (2023). Telomere length associates with chronological age and mortality across racially diverse pulmonary fibrosis cohorts. NATURE COMMUNICATIONS, 14(1). doi:10.1038/s41467-023-37193-6

Huang, Y., Guzy, R., Ma, S. -F., Bonham, C. A., Jou, J., Schulte, J. J., . . . Noth, I. (2023). Central lung gene expression associates with myofibroblast features in idiopathic pulmonary fibrosis. BMJ OPEN RESPIRATORY RESEARCH, 10(1). doi:10.1136/bmjresp-2022-001391

Kim, J. S., Kim, J., Yin, X., Hiura, G. T., Anderson, M. R., Hoffman, E. A., . . . Oelsner, E. C. (2023). Associations of hiatus hernia with CT-based interstitial lung changes: the MESA Lung Study. EUROPEAN RESPIRATORY JOURNAL, 61(1). doi:10.1183/13993003.03173-2021

2022

Podolanczuk, A., Kim, J. S., Cooper, C. B., Lasky, J. A., Murray, S., Oldham, J. M., . . . Martinez, F. (2022). Design and rationale for the prospective treatment efficacy in IPF using genotype for NAC selection (PRECISIONS) clinical trial. BMC PULMONARY MEDICINE, 22(1). doi:10.1186/s12890-022-02281-8

Geng, Y., Li, L., Yan, J., Liu, K., Yang, A., Zhang, L., . . . Fan, X. (2022). Author Correction: PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis.. Nature communications, 13(1), 7749. doi:10.1038/s41467-022-35543-4

Zhang, D., Newton, C. A., Wang, B., Povysil, G., Noth, I., Martinez, F. J., . . . Garcia, C. K. (2022). Utility of whole genome sequencing in assessing risk and clinically relevant outcomes for pulmonary fibrosis. EUROPEAN RESPIRATORY JOURNAL, 60(6). doi:10.1183/13993003.00577-2022

Geng, Y., Li, L., Yan, J., Liu, K., Yang, A., Zhang, L., . . . Fan, X. (2022). PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis. NATURE COMMUNICATIONS, 13(1). doi:10.1038/s41467-022-34870-w

Bonham, C. A., & Noth, I. (2022). Idiopathic Pulmonary Fibrosis Genetic Risk Factors, Function, and Mechanisms? The Concepts Are Starting to Gel. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206(10), 1197-1199. doi:10.1164/rccm.202208-1591ED

Fainberg, H. P., Oldham, J. M., Molyneaux, P. L., Allen, R. J., Kraven, L. M., Fahy, W. A., . . . Jenkins, R. G. (2022). Forced vital capacity trajectories in patients with idiopathic pulmonary fibrosis: a secondary analysis of a multicentre, prospective, observational cohort. LANCET DIGITAL HEALTH, 4(12), E862-E872. doi:10.1016/S2589-7500(22)00173-X

Partanen, J. J., Happola, P., Zhou, W., Lehisto, A. A., Ainola, M., Sutinen, E., . . . Koskela, J. T. (2022). Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics. CELL GENOMICS, 2(10). doi:10.1016/j.xgen.2022.100181

Zhang, D., Povysil, G., Newton, C. A., Maher, T. M., Molyneaux, P. L., Noth, I., . . . Garcia, C. K. (2022). Genome-wide Enrichment of TERT Rare Variants in Idiopathic Pulmonary Fibrosis Patients of Latino Ancestry. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206(7), 903-905. doi:10.1164/rccm.202203-0622LE

Allen, R. J., Oldham, J. M., Jenkins, D. A., Leavy, O. C., Guillen-Guio, B., Melbourne, C. A., . . . Wain, L. V. (2023). Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study. LANCET RESPIRATORY MEDICINE, 11(1), 65-73. doi:10.1016/S2213-2600(22)00251-X

Kim, J. S., Manichaikul, A. W., Hoffman, E. A., Balte, P., Anderson, M. R., Bernstein, E. J., . . . Podolanczuk, A. J. (2023). MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study. THORAX, 78(6), 566-573. doi:10.1136/thorax-2021-218139

Lipinski, J. H., Erb-Downward, J. R., Huffnagle, G. B., Flaherty, K. R., Martinez, F. J., Moore, B. B., . . . O'Dwyer, D. N. (2022). Toll-Interacting Protein and Altered Lung Microbiota in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206(2), 224-227. doi:10.1164/rccm.202111-2590LE

Zhang, D., Povysil, G., Kobeissy, P. H., Li, Q., Wang, B., Amelotte, M., . . . Garcia, C. K. (2022). Rare and Common Variants in KIF15 Contribute to Genetic Risk of Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 206(1), 56-69. doi:10.1164/rccm.202110-2439OC

Allen, R. J., Stockwell, A., Oldham, J. M., Guillen-Guio, B., Schwartz, D. A., Maher, T. M., . . . Wain, L. V. (2022). Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis. THORAX, 77(8), 829-833. doi:10.1136/thoraxjnl-2021-218577

Kraven, L. M., Taylor, A. R., Molyneaux, P. L., Maher, T., McDonough, J., Mura, M., . . . Wain, L. V. (2022). Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis. THORAX. doi:10.1136/thoraxjnl-2021-218563

Todd, J. L., Neely, M. L., Overton, R., Mulder, H., Roman, J., Lasky, J. A., . . . Palmer, S. M. (2022). Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort (Jan, 10.1007/s00408-021-00505-y, 2022). LUNG, 200(1), 19. doi:10.1007/s00408-022-00516-3

Todd, J. L., Neely, M. L., Overton, R., Mulder, H., Roman, J., Lasky, J. A., . . . Palmer, S. M. (2022). Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort. LUNG, 200(1), 11-18. doi:10.1007/s00408-021-00505-y

2021

Kim, J. S., Anderson, M. R., Bernstein, E. J., Oelsner, E. C., Raghu, G., Noth, I., . . . Podolanczuk, A. J. (2021). Associations of D-Dimer with Computed Tomographic Lung Abnormalities, Serum Biomarkers of Lung Injury, and Forced Vital Capacity MESA Lung Study. ANNALS OF THE AMERICAN THORACIC SOCIETY, 18(11), 1839-1848. doi:10.1513/AnnalsATS.202012-1557OC

Biblowitz, K., Lee, C., Zhu, D., Noth, I., Vij, R., Strek, M. E., . . . Adegunsoye, A. (2021). Association of antinuclear antibody seropositivity with inhaled environmental exposures in patients with interstitial lung disease. ERJ OPEN RESEARCH, 7(4). doi:10.1183/23120541.00254-2021

Martinez, F. J., Anstrom, K. J., & Noth, I. (2021). Antimicrobial Therapy and Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis Reply. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(11), 1071-1072. doi:10.1001/jama.2021.11813

Huang, Y., Oldham, J. M., Ma, S. -F., Unterman, A., Liao, S. -Y., Barros, A. J., . . . Noth, I. (2021). Blood Transcriptomics Predicts Progression of Pulmonary Fibrosis and Associated Natural Killer Cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 204(2), 197-208. doi:10.1164/rccm.202008-3093OC

Noth, I., Cottin, V., Chaudhuri, N., Corte, T. J., Johannson, K. A., Wijsenbeek, M., . . . Maher, T. M. (2021). Home spirometry in patients with idiopathic pulmonary fibrosis: data from the INMARK trial. EUROPEAN RESPIRATORY JOURNAL, 58(1). doi:10.1183/13993003.01518-2020

Guardela, B. M. J., Sun, J., Zhang, T., Xu, B., Balnis, J., Huang, Y., . . . Herazo-Maya, J. D. (2021). 50-gene risk profiles in peripheral blood predict COVID-19 outcomes: A retrospective, multicenter cohort study. EBIOMEDICINE, 69. doi:10.1016/j.ebiom.2021.103439

Hohmann, M. S., Habiel, D. M., Espindola, M. S., Huang, G., Jones, I., Narayanan, R., . . . Hogaboam, C. M. (2021). Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. JCI INSIGHT, 6(11). doi:10.1172/jci.insight.141061

Martinez, F. J., Yow, E., Flaherty, K. R., Snyder, L. D., Durheim, M. T., Wisniewski, S. R., . . . Noth, I. (2021). Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 325(18), 1841-1851. doi:10.1001/jama.2021.4956

Budzikowski, J. D., Foy, J. J., Rashid, A. A., Chung, J. H., Noth, I., & Armato, S. G. I. I. I. (2021). Radiomics-based assessment of idiopathic pulmonary fibrosis is associated with genetic mutations and patient survival. JOURNAL OF MEDICAL IMAGING, 8(3). doi:10.1117/1.JMI.8.3.031903

Leavy, O. C., Ma, S. -F., Molyneaux, P. L., Maher, T. M., Oldham, J. M., Flores, C., . . . Allen, R. J. (2021). Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 203(6), 775-778. doi:10.1164/rccm.202008-3211LE

Adegunsoye, A., Morisset, J., Newton, C. A., Oldham, J. M., Vittinghoff, E., Linderholm, A. L., . . . Ley, B. (2021). Leukocyte telomere length and mycophenolate therapy in chronic hypersensitivity pneumonitis. EUROPEAN RESPIRATORY JOURNAL, 57(3). doi:10.1183/13993003.02872-2020

Espindola, M. S., Habiel, D. M., Coelho, A. L., Stripp, B., Parks, W. C., Oldham, J., . . . Hogaboam, C. M. (2021). Differential Responses to Targeting Matrix Metalloproteinase 9 in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 203(4), 458-470. doi:10.1164/rccm.201910-1977OC

Podolanczuk, A. J., Noth, I., & Raghu, G. (2021). Idiopathic pulmonary fibrosis: prime time for a precision-based approach to treatment with N-acetylcysteine. EUROPEAN RESPIRATORY JOURNAL, 57(1). doi:10.1183/13993003.03551-2020

2020

Wang, B. R., Edwards, R., Freiheit, E. A., Ma, Y., Burg, C., de Andrade, J., . . . Flaherty, K. R. (2020). The Pulmonary Fibrosis Foundation Patient Registry Rationale, Design, and Methods. ANNALS OF THE AMERICAN THORACIC SOCIETY, 17(12), 1620-1628. doi:10.1513/AnnalsATS.202001-035SD

Crews, M. S., Bartholmai, B. J., Adegunsoye, A., Oldham, J. M., Montner, S. M., Karwoski, R. A., . . . Chung, J. H. (2020). Automated CT Analysis of Major Forms of Interstitial Lung Disease. JOURNAL OF CLINICAL MEDICINE, 9(11). doi:10.3390/jcm9113776

Noth, I., & Otoupalova, E. (2020). The Bloom Is in Bud for Interstitial Lung Diseases. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 202(10), 1338-1339. doi:10.1164/rccm.202007-2855ED

Kim, J. S., Steffen, B. T., Podolanczuk, A. J., Kawut, S. M., Noth, I., Raghu, G., . . . Lederer, D. J. (2021). Associations of ω-3 Fatty Acids With Interstitial Lung Disease and Lung Imaging Abnormalities Among Adults. AMERICAN JOURNAL OF EPIDEMIOLOGY, 190(1), 95-108. doi:10.1093/aje/kwaa168

Casanova, N. G., Zhou, T., Gonzalez-Garay, M. L., Lussier, Y. A., Sweiss, N., Ma, S. -F., . . . Garcia, J. G. N. (2021). MicroRNA and protein-coding gene expression analysis in idiopathic pulmonary fibrosis yields novel biomarker signatures associated to survival. TRANSLATIONAL RESEARCH, 228, 1-12. doi:10.1016/j.trsl.2020.07.009

Graham, J., Ventura, I. B., Newton, C. A., Lee, C., Boctor, N., Pugashetti, J. V., . . . Oldham, J. M. (2020). Myositis-specific antibodies identify a distinct interstitial pneumonia with autoimmune features phenotype. EUROPEAN RESPIRATORY JOURNAL, 56(6). doi:10.1183/13993003.01205-2020

Snyder, L. D., Mosher, C., Holtze, C. H., Lancaster, L. H., Flaherty, K. R., Noth, I., . . . Whelan, T. P. M. (2020). Time to diagnosis of idiopathic pulmonary fibrosis in the IPF-PRO Registry. BMJ OPEN RESPIRATORY RESEARCH, 7(1). doi:10.1136/bmjresp-2020-000567

Adegunsoye, A., Neborak, J. M., Zhu, D., Cantrill, B., Garcia, N., Oldham, J. M., . . . Mokhlesi, B. (2020). CPAP Adherence, Mortality, and Progression-Free Survival in Interstitial Lung Disease and OSA. CHEST, 158(4), 1701-1712. doi:10.1016/j.chest.2020.04.067

Adegunsoye, A., Alqalyoobi, S., Linderholm, A., Bowman, W. S., Lee, C. T., Pugashetti, J. V., . . . Oldham, J. M. (2020). Circulating Plasma Biomarkers of Survival in Antifibrotic-Treated Patients With Idiopathic Pulmonary Fibrosis. CHEST, 158(4), 1526-1534. doi:10.1016/j.chest.2020.04.066

Todd, J. L., Vinisko, R., Liu, Y., Neely, M. L., Overton, R., Flaherty, K. R., . . . Belperio, J. A. (2020). Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort. BMC PULMONARY MEDICINE, 20(1). doi:10.1186/s12890-020-1103-4

Anstrom, K. J., Noth, I., Flaherty, K. R., Edwards, R. H., Albright, J., Baucom, A., . . . Martinez, F. J. (2020). Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial. RESPIRATORY RESEARCH, 21(1). doi:10.1186/s12931-020-1326-1

Guillen-Guio, B., Lorenzo-Salazar, J. M., Ma, S. -F., Hou, P. -C., Hernandez-Beeftink, T., Corrales, A., . . . Flores, C. (2020). Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study. LANCET RESPIRATORY MEDICINE, 8(3), 258-266. doi:10.1016/S2213-2600(19)30368-6

Alqalyoobi, S., Adegunsoye, A., Linderholm, A., Hrusch, C., Cutting, C., Ma, S. -F., . . . Oldham, J. M. (2020). Circulating Plasma Biomarkers of Progressive Interstitial Lung Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 201(2), 250-253. doi:10.1164/rccm.201907-1343LE

2019

Hobbs, B. D., Putman, R. K., Araki, T., Nishino, M., Gudmundsson, G., Gudnason, V., . . . Viviano, L. (2019). Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(11), 1402-1413. doi:10.1164/rccm.201903-0511OC

Ley, B., Torgerson, D. G., Oldham, J. M., Adegunsoye, A., Liu, S., Li, J., . . . Wolters, P. J. (2019). Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(9), 1154-1163. doi:10.1164/rccm.201902-0360OC

Todd, J. L., Neely, M. L., Overton, R., Durham, K., Gulati, M., Huang, H., . . . Whelan, T. P. (2019). Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry. RESPIRATORY RESEARCH, 20(1). doi:10.1186/s12931-019-1190-z

Casanova, N., Zhou, T., Gonzalez-Garay, M. L., Rosas, I. O., Goldberg, H. J., Ryter, S. W., . . . Garcia, J. G. N. (2019). Low Dose Carbon Monoxide Exposure in Idiopathic Pulmonary Fibrosis Produces a CO Signature Comprised of Oxidative Phosphorylation Genes. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-50585-3

Noth, I., Wijsenbeek, M., Kolb, M., Bonella, F., Moros, L., Wachtlin, D., & Corte, T. J. (2019). Cardiovascular safety of nintedanib in subgroups by cardiovascular risk at baseline in the TOMORROW and INPULSIS trials. EUROPEAN RESPIRATORY JOURNAL, 54(3). doi:10.1183/13993003.01797-2018

Newton, C. A., Zhang, D., Oldham, J. M., Kozlitina, J., Ma, S. -F., Martinez, F. J., . . . Garcia, C. K. (2019). Telomere Length and Use of Immunosuppressive Medications in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(3), 336-347. doi:10.1164/rccm.201809-1646OC

Maher, T. M., Stowasser, S., Nishioka, Y., White, E. S., Cottin, V., Noth, I., . . . Jenkins, R. G. (2019). Biomarkers of extracellular matrix turnover in patients with idiopathic pulmonary fibrosis given nintedanib (INMARK study): a randomised, placebo-controlled study. LANCET RESPIRATORY MEDICINE, 7(9), 771-779. doi:10.1016/S2213-2600(19)30255-3

Moore, C., Blumhagent, R. Z., Yang, I. V., Walts, A., Powers, J., Walker, T., . . . Schwartz, D. A. (2019). Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200(2), 199-208. doi:10.1164/rccm.201810-1891OC

Adegunsoye, A., Oldham, J. M., Bellam, S. K., Montner, S., Churpek, M. M., Noth, I., . . . Chung, J. H. (2019). Computed Tomography Honeycombing Identifies a Progressive Fibrotic Phenotype with Increased Mortality across Diverse Interstitial Lung Diseases. ANNALS OF THE AMERICAN THORACIC SOCIETY, 16(5), 580-588. doi:10.1513/AnnalsATS.201807-443OC

Adegunsoye, A., Oldham, J. M., Sperling, A. I., Noth, I., Strek, M. E., & Chung, J. H. (2019). Prognostic Impact of Mediastinal Lymph Nodes in Interstitial Lung Diseases: Is Environmental Exposure the Offender? Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(8), 1041-1042. doi:10.1164/rccm.201811-2208LE

Lorenzo-Salazar, J. M., Ma, S. -F., Jou, J., Hou, P. -C., Guillen-Guio, B., Allen, R. J., . . . Flores, C. (2019). Novel idiopathic pulmonary fibrosis susceptibility variants revealed by deep sequencing. ERJ OPEN RESEARCH, 5(2). doi:10.1183/23120541.00071-2019

Newton, C. A., Oldham, J. M., Ley, B., Anand, V., Adegunsoye, A., Liu, G., . . . Garcia, C. K. (2019). Telomere length and genetic variant associations with interstitial lung disease progression and survival. EUROPEAN RESPIRATORY JOURNAL, 53(4). doi:10.1183/13993003.01641-2018

Adegunsoye, A., Oldham, J. M., Bonham, C., Hrusch, C., Nolan, P., Klejch, W., . . . Chung, J. H. (2019). Prognosticating Outcomes in Interstitial Lung Disease by Mediastinal Lymph Node Assessment An Observational Cohort Study with Independent Validation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 199(6), 747-759. doi:10.1164/rccm.201804-0761OC

Barros, A., Oldham, J., & Noth, I. (2019). Genetics of Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 357(5), 379-383. doi:10.1016/j.amjms.2019.02.009

Sturek, J., & Noth, I. (2019). Wandering out of the GWAS wilderness: a new pathway paradigm for complex disease genetics. THORAX, 74(3), 215-216. doi:10.1136/thoraxjnl-2018-212511

Adegunsoye, A., Vij, R., & Noth, I. (2019). Integrating Genomics Into Management of Fibrotic Interstitial Lung Disease. CHEST, 155(5), 1026-1040. doi:10.1016/j.chest.2018.12.011

Bonham, C. A., Hrusch, C. L., Blaine, K. M., Manns, S. T., Vij, R., Oldham, J. M., . . . Sperling, A. I. (2019). T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival.. Respiratory medicine: X, 1, 100002. doi:10.1016/j.yrmex.2019.100002

2018

Bermea, R. S., Adegunsoye, A., Oldham, J., Ventura, I., Lee, C., Chung, J. H., . . . Vij, R. (2019). Anti-RNA binding protein positivity in idiopathic interstitial pneumonia. RESPIRATORY MEDICINE, 146, 23-27. doi:10.1016/j.rmed.2018.11.015

Celada, L. J., Kropski, J. A., Herazo-Maya, J. D., Luo, W., Creecy, A., Abad, A. T., . . . Drake, W. P. (2018). PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. SCIENCE TRANSLATIONAL MEDICINE, 10(460). doi:10.1126/scitranslmed.aar8356

Raghu, G., Pellegrini, C. A., Yow, E., Flaherty, K. R., Meyer, K., Noth, I., . . . Collard, H. R. (2018). Laparoscopic anti-reflux surgery for the treatment of idiopathic pulmonary fibrosis (WRAP-IPF): a multicentre, randomised, controlled phase 2 trial. LANCET RESPIRATORY MEDICINE, 6(9), 707-714. doi:10.1016/S2213-2600(18)30301-1

Noth, I., Oelberg, D., Kaul, M., Conoscenti, C. S., & Raghu, G. (2018). Safety and tolerability of nintedanib in patients with idiopathic pulmonary fibrosis in the USA. EUROPEAN RESPIRATORY JOURNAL, 52(1). doi:10.1183/13993003.02106-2017

Adegunsoye, A., Oldham, J. M., Bellam, S. K., Chung, J. H., Chung, P. A., Biblowitz, K. M., . . . Strek, M. E. (2018). African-American race and mortality in interstitial lung disease: a multicentre propensity-matched analysis. EUROPEAN RESPIRATORY JOURNAL, 51(6). doi:10.1183/13993003.00255-2018

Oldham, J. M., Adegunsoye, A., Khera, S., Lafond, E., Noth, I., Strek, M. E., . . . Chung, J. H. (2018). Underreporting of Interstitial Lung Abnormalities on Lung Cancer Screening Computed Tomography. ANNALS OF THE AMERICAN THORACIC SOCIETY, 15(6), 764-766. doi:10.1513/AnnalsATS.201801-053RL

Chung, J. H., Oldham, J. M., Montner, S. M., Vij, R., Adegunsoye, A., Husain, A. N., . . . Strek, M. E. (2018). CT-Pathologic Correlation of Major Types of Pulmonary Fibrosis: Insights for Revisions to Current Guidelines. AMERICAN JOURNAL OF ROENTGENOLOGY, 210(5), 1034-1041. doi:10.2214/AJR.17.18947

Oldham, J. M., Witt, L. J., Adegunsoye, A., Chung, J. H., Lee, C., Hsu, S., . . . Noth, I. (2018). N-acetylcysteine exposure is associated with improved survival in anti-nuclear antibody seropositive patients with usual interstitial pneumonia. BMC PULMONARY MEDICINE, 18. doi:10.1186/s12890-018-0599-3

Jouneau, S., Noth, I., Wijsenbeek, M., Kolb, M., Bonella, F., Wachtlin, D., & Corte, T. J. (2018). Sécurité cardiovasculaire du nintédanib dans des sous-groupes selon le risque cardiovasculaire initial dans les essais TOMORROW et INPULSIS. Revue des Maladies Respiratoires, 35, A143-A144. doi:10.1016/j.rmr.2017.10.316

Maher, T. M., Stowasser, S., Nishioka, Y., White, E. S., Cottin, V., Noth, I., . . . Jenkins, R. G. (2018). Investigating the effects of nintedanib on biomarkers of extracellular matrix turnover in patients with IPF: design of the randomised placebo-controlled INMARK®trial. BMJ OPEN RESPIRATORY RESEARCH, 5(1). doi:10.1136/bmjresp-2018-000325

2017

Chung, J. H., Cox, C. W., Montner, S. M., Adegunsoye, A., Oldham, J. M., Husain, A. N., . . . Strek, M. E. (2018). CT Features of the Usual Interstitial Pneumonia Pattern: Differentiating Connective Tissue Disease-Associated Interstitial Lung Disease From Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF ROENTGENOLOGY, 210(2), 307-313. doi:10.2214/AJR.17.18384

Rosas, I. O., Goldberg, H. J., Collard, H. R., El-Chemaly, S., Flaherty, K., Hunninghake, G. M., . . . Choi, A. M. K. (2018). A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis. CHEST, 153(1), 94-104. doi:10.1016/j.chest.2017.09.052

Allen, R. J., Porte, J., Braybrooke, R., Flores, C., Fingerlin, T. E., Oldham, J. M., . . . Jenkins, R. G. (2017). Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. LANCET RESPIRATORY MEDICINE, 5(11), 869-880. doi:10.1016/S2213-2600(17)30387-9

Adegunsoye, A., Oldham, J. M., Chung, J. H., Montner, S. M., Lee, C., Witt, L. J., . . . Churpek, M. (2018). Phenotypic Clusters Predict Outcomes in a Longitudinal Interstitial Lung Disease Cohort. CHEST, 153(2), 349-360. doi:10.1016/j.chest.2017.09.026

Herazo-Maya, J. D., Sun, J., Molyneaux, P. L., Li, Q., Villalba, J. A., Tzouvelekis, A., . . . Kaminski, N. (2017). Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study. LANCET RESPIRATORY MEDICINE, 5(11), 857-868. doi:10.1016/S2213-2600(17)30349-1

Carlin, B. W., Schuldheisz, S. K., Noth, I., & Criner, G. J. (2017). Individualizing the selection of long-acting bronchodilator therapy for patients with COPD: considerations in primary care. POSTGRADUATE MEDICINE, 129(7), 725-733. doi:10.1080/00325481.2017.1353885

Huang, Y., Ma, S. -F., Espindola, M. S., Vij, R., Oldham, J. M., Huffnagle, G. B., . . . Noth, I. (2017). Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 196(2), 208-219. doi:10.1164/rccm.201607-1525OC

Chung, J. H., Montner, S. M., Adegunsoye, A., Oldham, J. M., Husain, A. N., Vij, R., . . . Strek, M. E. (2017). CT findings associated with survival in chronic hypersensitivity pneumonitis. EUROPEAN RADIOLOGY, 27(12), 5127-5135. doi:10.1007/s00330-017-4936-3

Adegunsoye, A., Oldham, J. M., Fernández Pérez, E. R., Hamblin, M., Patel, N., Tener, M., . . . Vij, R. (2017). Outcomes of immunosuppressive therapy in chronic hypersensitivity pneumonitis.. ERJ open research, 3(3), 16-2017. doi:10.1183/23120541.00016-2017

Hrusch, C. L., Manns, S. T., Bryazka, D., Casaos, J., Bonham, C. A., Jaffery, M. R., . . . Sperling, A. I. (2018). ICOS protects against mortality from acute lung injury through activation of IL-5+ ILC2s. MUCOSAL IMMUNOLOGY, 11(1), 61-70. doi:10.1038/mi.2017.42

Adegunsoye, A., Oldham, J. M., Valenzi, E., Lee, C., Witt, L. J., Chen, L., . . . Husain, A. N. (2017). Interstitial Pneumonia With Autoimmune Features Value of Histopathology. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 141(7), 960-969. doi:10.5858/arpa.2016-0427-OA

Haycock, P. C., Burgess, S., Nounu, A., Zheng, J., Okoli, G. N., Bowden, J., . . . Smith, G. D. (2017). Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study. JAMA ONCOLOGY, 3(5), 636-651. doi:10.1001/jamaoncol.2016.5945

O'Dwyer, D. N., Norman, K. C., Xia, M., Huang, Y., Gurczynski, S. J., Ashley, S. L., . . . Moore, B. B. (2017). The peripheral blood proteome signature of idiopathic pulmonary fibrosis is distinct from normal and is associated with novel immunological processes. SCIENTIFIC REPORTS, 7. doi:10.1038/srep46560

Chung, J. H., Montner, S. M., Adegunsoye, A., Lee, C., Oldham, J. M., Husain, A. N., . . . Strek, M. E. (2017). CT Findings, Radiologic-Pathologic Correlation, and Imaging Predictors of Survival for Patients With Interstitial Pneumonia With Autoimmune Features. AMERICAN JOURNAL OF ROENTGENOLOGY, 208(6), 1229-1236. doi:10.2214/AJR.16.17121

Raghu, G., Noth, I., & Martinez, F. (2017). N-acetylcysteine for idiopathic pulmonary fibrosis: the door is still open. LANCET RESPIRATORY MEDICINE, 5(1), E1-E2. doi:10.1016/S2213-2600(16)30327-7

Adegunsoye, A., Oldham, J. M., Husain, A. N., Chen, L., Hsu, S., Montner, S., . . . Strek, M. E. (2017). Autoimmune Hypothyroidism As a Predictor of Morality in Chronic Hypersensitivity Pneumonitis. FRONTIERS IN MEDICINE, 4. doi:10.3389/fmed.2017.00170

2016

Singla, S., Zhou, T., Javaid, K., Abbasi, T., Casanova, N., Zhang, W., . . . Machado, R. F. (2016). Expression profiling elucidates a molecular gene signature for pulmonary hypertension in sarcoidosis. PULMONARY CIRCULATION, 6(4), 465-471. doi:10.1086/688316

Oldham, J. M., Lee, C., Valenzi, E., Witt, L. J., Adegunsoye, A., Hsu, S., . . . Strek, M. E. (2016). Azathioprine response in patients with fibrotic connective tissue disease-associated interstitial lung disease. RESPIRATORY MEDICINE, 121, 117-122. doi:10.1016/j.rmed.2016.11.007

Oldham, J. M., Noth, I., & Martinez, F. J. (2016). Pharmacogenetics and interstitial lung disease. CURRENT OPINION IN PULMONARY MEDICINE, 22(5), 456-465. doi:10.1097/MCP.0000000000000289

Noth, I. (2016). When Is It More Than Just a Spicy Meal?. JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, 26(7), 499-500. doi:10.1089/lap.2016.29007.in

Oldham, J. M., Adegunsoye, A., Valenzi, E., Lee, C., Witt, L., Chen, L., . . . Strek, M. E. (2016). Characterisation of patients with interstitial pneumonia with autoimmune features. EUROPEAN RESPIRATORY JOURNAL, 47(6), 1767-1775. doi:10.1183/13993003.01565-2015

Oldham, J. M., Strek, M. E., & Noth, I. (2016). Idiopathic Pulmonary Fibrosis and Hypothyroidism Cannot Forget Subclinical Disease and Difficult-to-Eliminate Corticosteroids Response. CHEST, 149(2), 600-601. doi:10.1016/j.chest.2015.11.014

Maher, T., Noth, I., Allinger, A., Kaul, M., Conoscenti, C. S., & Oelberg, D. (2016). SAFETY AND TOLERABILITY OF NINTEDANIB IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS (IPF): ONE-YEAR DATA FROM POST-MARKETING SURVEILLANCE IN THE UNITED STATES. THORAX, 71, A175. doi:10.1136/thoraxjnl-2016-209333.311

Adegunsoye, A., Hrusch, C. L., Bonham, C. A., Jaffrey, M. R., Blaine, K. M., Sullivan, M., . . . Sperling, A. I. (2016). Skewed Lung CCR4 to CCR6 CD4+ T Cell Ratio in Idiopathic Pulmonary Fibrosis Is Associated with Pulmonary Function. FRONTIERS IN IMMUNOLOGY, 7. doi:10.3389/fimmu.2016.00516

2015

Oldham, J. M., Ma, S. -F., Martinez, F. J., Anstrom, K. J., Raghu, G., Schwartz, D. A., . . . Noth, I. (2015). TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 192(12), 1475-1482. doi:10.1164/rccm.201505-1010OC

Huang, Y., Ma, S. -F., Vij, R., Oldham, J. M., Herazo-Maya, J., Broderick, S. M., . . . Noth, I. (2015). A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis. BMC PULMONARY MEDICINE, 15. doi:10.1186/s12890-015-0142-8

Oldham, J. M., Kumar, D., Lee, C., Patel, S. B., Takahashi-Manns, S., Demchuk, C., . . . Noth, I. (2015). Thyroid Disease Is Prevalent and Predicts Survival in Patients With Idiopathic Pulmonary Fibrosis. CHEST, 148(3), 692-700. doi:10.1378/chest.14-2714

Huang, L. S., Berdyshev, E. V., Tran, J. T., Xie, L., Chen, J., Ebenezer, D. L., . . . Natarajan, V. (2015). Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy. THORAX, 70(12), 1138-1148. doi:10.1136/thoraxjnl-2014-206684

Fischer, A., Antoniou, K. M., Brown, K. K., Cadranel, J., Corte, T. J., du Bois, R. M., . . . Cottin, V. (2015). An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features. EUROPEAN RESPIRATORY JOURNAL, 46(4), 976-987. doi:10.1183/13993003.00150-2015

Vij, R., Denton, C. P., & Noth, I. (2015). Molecular Phenotyping A Guide to Improving Detection of Interstitial Lung Disease in Patients with Rheumatoid Arthritis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(12), 1349-1350. doi:10.1164/rccm.201504-0751ED

Stanley, S. E., Noth, I., & Armanios, M. (2015). What the Genetics "RTEL"ing Us about Telomeres and Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(6), 608-610. doi:10.1164/rccm.201501-0119ED

Wilkes, D. S., Chew, T., Flaherty, K. R., Frye, S., Gibson, K. F., Kaminski, N., . . . Rothhaar, K. (2015). Oral immunotherapy with type V collagen in idiopathic pulmonary fibrosis. EUROPEAN RESPIRATORY JOURNAL, 45(5), 1393-1402. doi:10.1183/09031936.00105314

2014

Stuart, B. D., Lee, J. S., Kozlitina, J., Noth, I., Devine, M. S., Glazer, C. S., . . . Garcia, C. K. (2014). Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation. LANCET RESPIRATORY MEDICINE, 2(7), 557-565. doi:10.1016/S2213-2600(14)70124-9

Huang, L. S., Mathew, B., Li, H., Zhao, Y., Ma, S. -F., Noth, I., . . . Natarajan, V. (2014). The Mitochondrial Cardiolipin Remodeling Enzyme Lysocardiolipin Acyltransferase Is a Novel Target in Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 189(11), 1402-1415. doi:10.1164/rccm.201310-1917OC

Han, M. K., Zhou, Y., Murray, S., Tayob, N., Noth, I., Lama, V. N., . . . Martinez, F. J. (2014). Lung microbiome and disease progression in idiopathic pulmonary fibrosis: an analysis of the COMET study. LANCET RESPIRATORY MEDICINE, 2(7), 548-556. doi:10.1016/S2213-2600(14)70069-4

Sweiss, N. J., Noth, I., Mirsaeidi, M., Zhang, W., Naureckas, E. T., Hogarth, D. K., . . . Baughman, R. P. (2014). EFFICACY RESULTS OF A 52-WEEK TRIAL OF ADALIMUMAB IN THE TREATMENT OF REFRACTORY SARCOIDOSIS. SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES, 31(1), 46-54. Retrieved from https://www.webofscience.com/

Oldham, J. M., & Noth, I. (2014). Idiopathic pulmonary fibrosis: Early detection and referral. RESPIRATORY MEDICINE, 108(6), 819-829. doi:10.1016/j.rmed.2014.03.008

Noth, I., & Olman, M. A. (2014). Rationale for Anticoagulant Therapy of Pulmonary Fibrosis Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 189(3), 363. doi:10.1164/rccm.201307-1328LE

Blackwell, T. S., Tager, A. M., Borok, Z., Moore, B. B., Schwartz, D. A., Anstrom, K. J., . . . Eu, J. P. (2014). Future Directions in Idiopathic Pulmonary Fibrosis Research. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 189(2), 214-222. doi:10.1164/rccm.201306-1141WS

2013

Wei, R., Li, C., Zhang, M., Jones-Hall, Y. L., Myers, J. L., Noth, I., & Liu, W. (2014). Association between MUC5B and TERT polymorphisms and different interstitial lung disease phenotypes. TRANSLATIONAL RESEARCH, 163(5), 494-502. doi:10.1016/j.trsl.2013.12.006

Noth, I., & Kaminski, N. (2013). Idiopathic Pulmonary Fibrosis: Time to Get Personal?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 188(12), 1392-1394. doi:10.1164/rccm.201311-1956ED

Takahashi, S. M., & Noth, I. (2013). GERD and idiopathic pulmonary fibrosis: cause or effect. Current Respiratory Care Reports, 2(4), 260-267. doi:10.1007/s13665-013-0066-9

Herazo-Maya, J. D., Noth, I., Duncan, S. R., Kim, S., Ma, S. -F., Tseng, G. C., . . . Kaminski, N. (2013). Peripheral Blood Mononuclear Cell Gene Expression Profiles Predict Poor Outcome in Idiopathic Pulmonary Fibrosis. SCIENCE TRANSLATIONAL MEDICINE, 5(205). doi:10.1126/scitranslmed.3005964

Allaix, M. E., Fisichella, P. M., Noth, I., Herbella, F. A., Segura, B. B., & Patti, M. G. (2014). Idiopathic Pulmonary Fibrosis and Gastroesophageal Reflux. Implications for Treatment. JOURNAL OF GASTROINTESTINAL SURGERY, 18(1), 100-104. doi:10.1007/s11605-013-2333-z

Sun, X., Ma, S. -F., Wade, M. S., Acosta-Herrera, M., Villar, J., Pino-Yanes, M., . . . Garcia, J. G. N. (2013). Functional promoter variants in sphingosine 1-phosphate receptor 3 associate with susceptibility to sepsis-associated acute respiratory distress syndrome. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 305(7), L467-L477. doi:10.1152/ajplung.00010.2013

Lee, J. S., Collard, H. R., Anstrom, K. J., Martinez, F. J., Noth, I., Roberts, R. S., . . . Raghu, G. (2013). Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials. LANCET RESPIRATORY MEDICINE, 1(5), 369-376. doi:10.1016/S2213-2600(13)70105-X

Peljto, A. L., Zhang, Y., Fingerlin, T. E., Ma, S. -F., Garcia, J. G. N., Richards, T. J., . . . Schwartz, D. A. (2013). Association Between the MUC5B Promoter Polymorphism and Survival in Patients With Idiopathic Pulmonary Fibrosis. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 309(21), 2232-2239. doi:10.1001/jama.2013.5827

Noth, I., & Olman, M. (2013). A Placebo-controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis: A Hidden Subgroup? Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187(9), 1030. doi:10.1164/rccm.201211-2060LE

Allaix, M. E., Fisichella, P. M., Noth, I., Mendez, B. M., & Patti, M. G. (2013). The Pulmonary Side of Reflux Disease: from Heartburn to Lung Fibrosis. JOURNAL OF GASTROINTESTINAL SURGERY, 17(8), 1526-1535. doi:10.1007/s11605-013-2208-3

Noth, I., Zhang, Y., Ma, S. -F., Flores, C., Barber, M., Huang, Y., . . . Garcia, J. G. N. (2013). Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. LANCET RESPIRATORY MEDICINE, 1(4), 309-317. doi:10.1016/S2213-2600(13)70045-6

Noth, I., & Olman, M. (2013). Warfarin in Idiopathic Pulmonary Fibrosis: Friend or Foe, Is It a Matter of Genes and Heparin? Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 187(2), 214. doi:10.1164/ajrccm.187.2.214

Huang, L. S., Berdyshev, E., Mathew, B., Fu, P., Gorshkova, I. A., He, D., . . . Natarajan, V. (2013). Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis. FASEB JOURNAL, 27(4), 1749-1760. doi:10.1096/fj.12-219634

2012

Cipriani, N. A., Strek, M., Noth, I., Gordon, I. O., Charbeneau, J., Krishnan, J. A., . . . Husain, A. N. (2012). Pathologic Quantification of Connective Tissue Disease-Associated Versus Idiopathic Usual Interstitial Pneumonia. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 136(10), 1253-1258. doi:10.5858/arpa.2012-0102-OA

Swigris, J. J., Han, M., Vij, R., Noth, I., Eisenstein, E. L., Anstrom, K. J., . . . Fairclough, D. (2012). The UCSD shortness of breath questionnaire has longitudinal construct validity in idiopathic pulmonary fibrosis. RESPIRATORY MEDICINE, 106(10), 1447-1455. doi:10.1016/j.rmed.2012.06.018

Noth, I., Anstrom, K. J., Calvert, S. B., de Andrade, J., Flaherty, K. R., Glazer, C., . . . Olman, M. A. (2012). A Placebo-Controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 186(1), 88-95. doi:10.1164/rccm.201202-0314OC

Vij, R., & Noth, I. (2012). Peripheral blood biomarkers in idiopathic pulmonary fibrosis. TRANSLATIONAL RESEARCH, 159(4), 218-227. doi:10.1016/j.trsl.2012.01.012

Noth, I., Vij, R., & Strek, M. E. (2012). Interstitial Lung Disease and Antinuclear Antibody Consider Nonspecific Interstitial Pneumonia Histology and Newer Antibodies Response. CHEST, 141(5), 1361. doi:10.1378/chest.12-0026

Noth, I., & Olman, M. (2012). Is Warfarin the Right Anticoagulant in Idiopathic Pulmonary Fibrosis? Reply. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 186(7), 693-694. doi:10.1164/ajrccm.186.7.693a

Zhou, T., Zhang, W., Sweiss, N. J., Chen, E. S., Moller, D. R., Knox, K. S., . . . Garcia, J. G. N. (2012). Peripheral Blood Gene Expression as a Novel Genomic Biomarker in Complicated Sarcoidosis. PLOS ONE, 7(9). doi:10.1371/journal.pone.0044818

2011

Noth, I., Gibson, K. F., & Drake, W. P. (2011). Where Next for Gene Expression Profiling? So Much Promise. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 184(10), 1102-1103. doi:10.1164/rccm.201109-1612ED

Noth, I., Zangan, S. M., Soares, R. V., Forsythe, A., Demchuk, C., Takahashi, S. M., . . . MacMahon, H. (2012). Prevalence of hiatal hernia by blinded multidetector CT in patients with idiopathic pulmonary fibrosis. EUROPEAN RESPIRATORY JOURNAL, 39(2), 344-351. doi:10.1183/09031936.00099910

Vij, R., Noth, I., & Strek, M. E. (2011). Autoimmune-Featured Interstitial Lung Disease A Distinct Entity. CHEST, 140(5), 1292-1299. doi:10.1378/chest.10-2662

Zhang, Y., Noth, I., Garcia, J. G. N., & Kaminski, N. (2011). A Variant in the Promoter of MUC5B and Idiopathic Pulmonary Fibrosis. NEW ENGLAND JOURNAL OF MEDICINE, 364(16), 1576-1577. doi:10.1056/NEJMc1013504

Xue, J., Gochuico, B. R., Alawad, A. S., Feghali-Bostwick, C. A., Noth, I., Nathan, S. D., . . . Duncan, S. R. (2011). The HLA Class II Allele DRB1*1501 Is Over-Represented in Patients with Idiopathic Pulmonary Fibrosis. PLOS ONE, 6(2). doi:10.1371/journal.pone.0014715

Soares, R. V., Forsythe, A., Hogarth, K., Sweiss, N. J., Noth, I., & Patti, M. G. (2011). Interstitial lung disease and gastroesophageal reflux disease: key role of esophageal function tests in the diagnosis and treatment.. Arquivos de gastroenterologia, 48(2), 91-97. doi:10.1590/s0004-28032011000200002

2010

White, S. R., Loisel, D. A., McConville, J. F., Stern, R., Tu, Y., Marroquin, B. A., . . . Ober, C. (2010). Levels of soluble human leukocyte antigen-G are increased in asthmatic airways. EUROPEAN RESPIRATORY JOURNAL, 35(4), 925-927. doi:10.1183/09031936.00164809

Anstrom, K. J., Kaner, R. J., Loyd, J. E., Roman, J., Brown, K. K., King, T. E. J., . . . Reynolds, H. Y. (2010). The IPFnet Strategy Creating a Comprehensive Approach in the Treatment of Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 181(6), 527-528. doi:10.1164/rccm.200903-0483ED