Jianhua Cang
Jefferson Scholars Foundation Professor, Biology
Charlottesville, VA 22904
Bio & Overview
Academic Information
- Department
- Biology
- Academic Title
- Jefferson Scholars Foundation Professor
Primary Education
- B.S., undefinedPeking (Beijing) Universitynull
- Ph.D., undefinedUniversity of Virginianull
- Postdoc, undefinedUniversity of California, San Diegonull
- Postdoc, undefinedUniversity of California, San Francisconull
Other Appointments
- Jefferson Scholars Foundation Professor, Neuroscience
Other Affiliations
- MSTP
- BIMS
Research Interests
Research Disciplines
- Neuroscience
Research Opportunities
- Molecular and Systems Neuroscience
PhD Programs
- Neuroscience
Selected Publications
2024
DePiero, V. J., Deng, Z., Chen, C., Savier, E. L., Chen, H., Wei, W., & Cang, J. (2024). Transformation of Motion Pattern Selectivity from Retina to Superior Colliculus.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 44(20), e1704232024. doi:10.1523/jneurosci.1704-23.2024
Miller, D. A., Grannonico, M., Liu, M., Savier, E., McHaney, K., Erisir, A., . . . Zhang, H. F. (2024). Visible-Light Optical Coherence Tomography Fibergraphy of the Tree Shrew Retinal Ganglion Cell Axon Bundles.. IEEE transactions on medical imaging, PP. doi:10.1109/tmi.2024.3380530
2023
Sun, C., Zheng, S., Perry, J. S. A., Norris, G. T., Cheng, M., Kong, F., . . . Hill, D. L. (2023). Maternal diet during early gestation influences postnatal taste activity-dependent pruning by microglia. JOURNAL OF EXPERIMENTAL MEDICINE, 220(12). doi:10.1084/jem.20212476
Fu, J., Tanabe, S., & Cang, J. (2023). Widespread and Multifaceted Binocular Integration in the Mouse Primary Visual Cortex. JOURNAL OF NEUROSCIENCE, 43(38), 6495-6507. doi:10.1523/JNEUROSCI.0925-23.2023
Liu, Y., Savier, E. L., DePiero, V. J., Chen, C., Schwalbe, D. C., Abraham-Fan, R. -J., . . . Cang, J. (2023). Mapping visual functions onto molecular cell types in the mouse superior colliculus. NEURON, 111(12). doi:10.1016/j.neuron.2023.03.036
2022
Tanabe, S., Fu, J., & Cang, J. (2022). Strong tuning for stereoscopic depth indicates orientation-specific recurrent circuitry in tree shrew V1. CURRENT BIOLOGY, 32(24), 5274-+. doi:10.1016/j.cub.2022.10.063
Skyberg, R., Tanabe, S., Chen, H., & Cang, J. (2022). Coarse-to-fine processing drives the efficient coding of natural scenes in mouse visual cortex. CELL REPORTS, 38(13). doi:10.1016/j.celrep.2022.110606
Li, C., McHaney, K. M., Sederberg, P. B., & Cang, J. (2022). Tree Shrews as an Animal Model for Studying Perceptual Decision-Making Reveal a Critical Role of Stimulus-Independent Processes in Guiding Behavior. ENEURO, 9(6). doi:10.1523/ENEURO.0419-22.2022
2021
Basso, M. A., Bickford, M. E., & Cang, J. (2021). Unraveling circuits of visual perception and cognition through the superior colliculus. NEURON, 109(6), 918-937. doi:10.1016/j.neuron.2021.01.013
Tohmi, M., Tanabe, S., & Cang, J. (2021). Motion Streak Neurons in the Mouse Visual Cortex. CELL REPORTS, 34(2). doi:10.1016/j.celrep.2020.108617
2020
Chen, H., Savier, E. L., DePiero, V. J., & Cang, J. (2021). Lack of Evidence for Stereotypical Direction Columns in the Mouse Superior Colliculus. JOURNAL OF NEUROSCIENCE, 41(3), 461-473. doi:10.1523/JNEUROSCI.1155-20.2020
2019
Savier, E. L., Chen, H., & Cang, J. (2019). Effects of Locomotion on Visual Responses in the Mouse Superior Colliculus. JOURNAL OF NEUROSCIENCE, 39(47), 9360-9368. doi:10.1523/JNEUROSCI.1854-19.2019
Xu, X., Cang, J., & Riecke, H. (2019). Development and Binocular Matching of Orientation Selectivity in Visual Cortex: A Computational Model. doi:10.1101/682211
2018
Barchini, J., Shi, X., Chen, H., & Cang, J. (2018). Bidirectional encoding of motion contrast in the mouse superior colliculus. ELIFE, 7. doi:10.7554/eLife.35261
Cang, J., Savier, E., Barchini, J., & Liu, X. (2018). Visual Function, Organization, and Development of the Mouse Superior Colliculus. ANNUAL REVIEW OF VISION SCIENCE, VOL 4, 4, 239-262. doi:10.1146/annurev-vision-091517-034142
Shi, X., Jin, Y., & Cang, J. (2018). Transformation of Feature Selectivity From Membrane Potential to Spikes in the Mouse Superior Colliculus.. Frontiers in cellular neuroscience, 12, 163. doi:10.3389/fncel.2018.00163
2017
Ahmad, T., Bouwman, R. A., Grigoras, I., Aldecoa, C., Hofer, C., Hoeft, A., . . . Wildes, T. (2017). In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study. EJSO, 43(12), 2324-2332. doi:10.1016/j.ejso.2017.08.002
Levine, J. N., Chen, H., Gu, Y., & Cang, J. (2017). Environmental Enrichment Rescues Binocular Matching of Orientation Preference in the Mouse Visual Cortex. JOURNAL OF NEUROSCIENCE, 37(24), 5822-5833. doi:10.1523/JNEUROSCI.3534-16.2017
Shi, X., Barchini, J., Ledesma, H. A., Koren, D., Jin, Y., Liu, X., . . . Cang, J. (2017). Retinal origin of direction selectivity in the superior colliculus. NATURE NEUROSCIENCE, 20(4), 550-+. doi:10.1038/nn.4498
2016
Gu, Y., & Cang, J. (2016). Binocular matching of thalamocortical and intracortical circuits in the mouse visual cortex. ELIFE, 5. doi:10.7554/eLife.22032
2015
Wang, L., Liu, M., Segraves, M. A., & Cang, J. (2015). Visual Experience Is Required for the Development of Eye Movement Maps in the Mouse Superior Colliculus. JOURNAL OF NEUROSCIENCE, 35(35), 12281-12286. doi:10.1523/JNEUROSCI.0117-15.2015
Krishnan, K., Wang, B. -S., Lu, J., Wang, L., Maffei, A., Cang, J., & Huang, Z. J. (2015). MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex.. Proceedings of the National Academy of Sciences of the United States of America, 112(34), E4782-E4791. doi:10.1073/pnas.1506499112
Inayat, S., Barchini, J., Chen, H., Feng, L., Liu, X., & Cang, J. (2015). Neurons in the Most Superficial Lamina of the Mouse Superior Colliculus Are Highly Selective for Stimulus Direction. JOURNAL OF NEUROSCIENCE, 35(20), 7992-8003. doi:10.1523/JNEUROSCI.0173-15.2015
Levine, J. N., Gu, Y., & Cang, J. (2015). Seeing Anew through Interneuron Transplantation.. Neuron, 86(4), 858-860. doi:10.1016/j.neuron.2015.05.003
Chen, H., Zhao, Y., Liu, M., Feng, L., Puyang, Z., Yi, J., . . . Liu, X. (2015). Progressive Degeneration of Retinal and Superior Collicular Functions in Mice With Sustained Ocular Hypertension. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 56(3), 1971-1984. doi:10.1167/iovs.14-15691
2014
Zhao, X., Liu, M., & Cang, J. (2014). Visual cortex modulates the magnitude but not the selectivity of looming-evoked responses in the superior colliculus of awake mice.. Neuron, 84(1), 202-213. doi:10.1016/j.neuron.2014.08.037
Sarnaik, R., Chen, H., Liu, X., & Cang, J. (2014). Genetic disruption of the On visual pathway affects cortical orientation selectivity and contrast sensitivity in mice. JOURNAL OF NEUROPHYSIOLOGY, 111(11), 2276-2286. doi:10.1152/jn.00558.2013
Chen, S., Yi, J., Inayat, S., Liu, W., Cang, J., & Zhang, H. F. (2014). Measuring absolute microvascular blood flow in cortex using visible-light optical coherence tomography.. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2014, 3881-3884. doi:10.1109/embc.2014.6944471
Liu, M., Wang, L., & Cang, J. (2014). Different roles of axon guidance cues and patterned spontaneous activity in establishing receptive fields in the mouse superior colliculus. FRONTIERS IN NEURAL CIRCUITS, 8. doi:10.3389/fncir.2014.00023
2013
Wang, B. -S., Feng, L., Liu, M., Liu, X., & Cang, J. (2013). Environmental Enrichment Rescues Binocular Matching of Orientation Preference in Mice that Have a Precocious Critical Period. NEURON, 80(1), 198-209. doi:10.1016/j.neuron.2013.07.023
Zhao, X., Chen, H., Liu, X., & Cang, J. (2013). Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus. JOURNAL OF NEUROSCIENCE, 33(31), 12751-+. doi:10.1523/JNEUROSCI.0095-13.2013
Cang, J., & Feldheim, D. A. (2013). Developmental mechanisms of topographic map formation and alignment.. Annual review of neuroscience, 36, 51-77. doi:10.1146/annurev-neuro-062012-170341
Feng, L., Zhao, Y., Yoshida, M., Chen, H., Yang, J. F., Kim, T. S., . . . Liu, X. (2013). Sustained Ocular Hypertension Induces Dendritic Degeneration of Mouse Retinal Ganglion Cells That Depends on Cell Type and Location. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(2), 1106-1117. doi:10.1167/iovs.12-10791
Sarnaik, R., Wang, B. -S., & Cang, J. (2014). Experience-dependent and independent binocular correspondence of receptive field subregions in mouse visual cortex.. Cerebral cortex (New York, N.Y. : 1991), 24(6), 1658-1670. doi:10.1093/cercor/bht027
Zhao, X., Liu, M., & Cang, J. (2013). Sublinear binocular integration preserves orientation selectivity in mouse visual cortex. NATURE COMMUNICATIONS, 4. doi:10.1038/ncomms3088
2012
Grimbert, F., & Cang, J. (2012). New model of retinocollicular mapping predicts the mechanisms of axonal competition and explains the role of reverse molecular signaling during development.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(28), 9755-9768. doi:10.1523/jneurosci.6180-11.2012
2011
Yoshida, M., Feng, L., Grimbert, F., Rangarajan, K. V., Buggele, W., Copenhagen, D. R., . . . Liu, X. (2011). Overexpression of Neurotrophin-3 Stimulates a Second Wave of Dopaminergic Amacrine Cell Genesis after Birth in the Mouse Retina. JOURNAL OF NEUROSCIENCE, 31(35), 12663-12673. doi:10.1523/JNEUROSCI.1100-11.2011
Rangarajan, K. V., Lawhn-Heath, C., Feng, L., Kim, T. S., Cang, J., & Liu, X. (2011). Detection of Visual Deficits in Aging DBA/2J Mice by Two Behavioral Assays. CURRENT EYE RESEARCH, 36(5), 481-491. doi:10.3109/02713683.2010.549600
2010
Wang, L., Sarnaik, R., Rangarajan, K., Liu, X., & Cang, J. (2010). Visual Receptive Field Properties of Neurons in the Superficial Superior Colliculus of the Mouse. JOURNAL OF NEUROSCIENCE, 30(49), 16573-16584. doi:10.1523/JNEUROSCI.3305-10.2010
Cantrell, D. R., Cang, J., Troy, J. B., & Liu, X. (2010). Non-Centered Spike-Triggered Covariance Analysis Reveals Neurotrophin-3 as a Developmental Regulator of Receptive Field Properties of ON-OFF Retinal Ganglion Cells. PLOS COMPUTATIONAL BIOLOGY, 6(10). doi:10.1371/journal.pcbi.1000967
Spruston, N., & Cang, J. (2010). Timing isn't everything.. Nature neuroscience, 13(3), 277-279. doi:10.1038/nn0310-277
Wang, B. -S., Sarnaik, R., & Cang, J. (2010). Critical period plasticity matches binocular orientation preference in the visual cortex.. Neuron, 65(2), 246-256. doi:10.1016/j.neuron.2010.01.002
Failor, S., Nguyen, V., Darcy, D. P., Cang, J., Wendland, M. F., Stryker, M. P., & McQuillen, P. S. (2010). Neonatal cerebral hypoxia-ischemia impairs plasticity in rat visual cortex.. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(1), 81-92. doi:10.1523/jneurosci.5656-08.2010