Sarah Flowers

Gibson, G. E., Feldman, H. H., Zhang, S., Flowers, S. A., & Luchsinger, J. A. (2022). Pharmacological thiamine levels as a therapeutic approach in Alzheimer's disease. FRONTIERS IN MEDICINE, 9. doi:10.3389/fmed.2022.1033272

McCann, M. S., Fernandez, H. R., Flowers, S. A., & Maguire-Zeiss, K. A. (2021). Polychlorinated biphenyls induce oxidative stress and metabolic responses in astrocytes. NEUROTOXICOLOGY, 86, 59-68. doi:10.1016/j.neuro.2021.07.001

Yang, F. N., Bronshteyn, M., Flowers, S. A., Dawson, M., Kumar, P., Rebeck, G. W., . . . Jiang, X. (2021). Low CD4⁺ cell count nadir exacerbates the impacts of APOE ε4 on functional connectivity and memory in adults with HIV. AIDS, 35(5), 727-736. doi:10.1097/QAD.0000000000002840

Fernandez, H. R., Varma, A., Flowers, S. A., & Rebeck, G. W. (2020). Cancer Chemotherapy Related Cognitive Impairment and the Impact of the Alzheimer's Disease Risk Factor APOE. CANCERS, 12(12). doi:10.3390/cancers12123842

Flowers, S. A., Thomsson, K. A., Ali, L., Huang, S., Mthembu, Y., Regmi, S. C., . . . Karlsson, N. G. (2020). Decrease of core 2 O-glycans on synovial lubricin in osteoarthritis reduces galectin-3 mediated crosslinking. JOURNAL OF BIOLOGICAL CHEMISTRY, 295(47), 16023-16036. doi:10.1074/jbc.RA120.012882

Flowers, S. A., & Rebeck, G. W. (2020). APOE in the normal brain. NEUROBIOLOGY OF DISEASE, 136. doi:10.1016/j.nbd.2019.104724

Gibson, G. E., Luchsinger, J. A., Cirio, R., Chen, H., Franchino-Elder, J., Hirsch, J. A., . . . Fonzetti, P. (2020). Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial. JOURNAL OF ALZHEIMERS DISEASE, 78(3), 989-1010. doi:10.3233/JAD-200896

Flowers, S. A., Grant, O. C., Woods, R. J., & Rebeck, G. W. (2020). O-glycosylation on cerebrospinal fluid and plasma apolipoprotein E differs in the lipid-binding domain. GLYCOBIOLOGY, 30(2), 74-85. doi:10.1093/glycob/cwz084

Wenzel, E. D., Speidell, A., Flowers, S. A., Wu, C., Avdoshina, V., & Mocchetti, I. (2019). Histone deacetylase 6 inhibition rescues axonal transport impairments and prevents the neurotoxicity of HIV-1 envelope protein gp120. CELL DEATH & DISEASE, 10. doi:10.1038/s41419-019-1920-7

Flowers, S. A., Lane, C. S., & Karlsson, N. G. (2019). Deciphering Isomers with a Multiple Reaction Monitoring Method for the Complete Detectable O-Glycan Repertoire of the Candidate Therapeutic, Lubricin. ANALYTICAL CHEMISTRY, 91(15), 9819-9827. doi:10.1021/acs.analchem.9b01485

Lane, C. S., McManus, K., Widdowson, P., Flowers, S. A., Powell, G., Anderson, I., & Campbell, J. L. (2019). Separation of Sialylated Glycan Isomers by Differential Mobility Spectrometry. ANALYTICAL CHEMISTRY, 91(15), 9916-9924. doi:10.1021/acs.analchem.9b01595

Flowers, S. A., Zieba, A., Ornros, J., Jin, C., Rolfson, O., Bjorkman, L. I., . . . Karlsson, N. G. (2017). Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-13558-y

Flowers, S. A., Kalamajski, S., Ali, L., Bjorkman, L. I., Raj, J. R., Aspberg, A., . . . Jin, C. (2017). Cartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions. OSTEOARTHRITIS AND CARTILAGE, 25(9), 1496-1504. doi:10.1016/j.joca.2017.03.016

Flowers, S. A., Zhou, X., Wu, J., Wang, Y., Makambi, K., Kallakury, B. V., . . . Goldman, R. (2016). Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck. ONCOTARGET, 7(28), 43177-43187. doi:10.18632/oncotarget.9506

Chaudhury, N. M. A., Proctor, G. B., Karlsson, N. G., Carpenter, G. H., & Flowers, S. A. (2016). Reduced Mucin-7 (Muc7) Sialylation and Altered Saliva Rheology in Sjogren's Syndrome Associated Oral Dryness. MOLECULAR & CELLULAR PROTEOMICS, 15(3), 1048-1059. doi:10.1074/mcp.M115.052993

Zad, M., Flowers, S. A., Bankvall, M., Jontell, M., & Karlsson, N. G. (2015). Salivary mucin MUC7 oligosaccharides in patients with recurrent aphthous stomatitis. CLINICAL ORAL INVESTIGATIONS, 19(8), 2147-2152. doi:10.1007/s00784-015-1495-3

Vitiazeva, V., Kattla, J. J., Flowers, S. A., Linden, S. K., Premaratne, P., Weijdegard, B., . . . Karlsson, N. G. (2015). The O-Linked Glycome and Blood Group Antigens ABO on Mucin-Type Glycoproteins in Mucinous and Serous Epithelial Ovarian Tumors. PLOS ONE, 10(6). doi:10.1371/journal.pone.0130197

Ali, L., Flowers, S. A., Jin, C., Bennet, E. P., Ekwall, A. -K. H., & Karlsson, N. G. (2014). The O-glycomap of Lubricin, a Novel Mucin Responsible for Joint Lubrication, Identified by Site-specific Glycopeptide Analysis. MOLECULAR & CELLULAR PROTEOMICS, 13(12), 3396-3409. doi:10.1074/mcp.M114.040865

Campbell, M. P., Nguyen-Khuong, T., Hayes, C. A., Flowers, S. A., Alagesan, K., Kolarich, D., . . . Karlsson, N. G. (2014). Validation of the curation pipeline of UniCarb-DB: Building a global glycan reference MS/MS repository. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1844(1), 108-116. doi:10.1016/j.bbapap.2013.04.018

Flowers, S. A., Ali, L., Lane, C. S., Olin, M., & Karlsson, N. G. (2013). Selected Reaction Monitoring to Differentiate and Relatively Quantitate Isomers of Sulfated and Unsulfated Core 1 O-Glycans from Salivary MUC7 Protein in Rheumatoid Arthritis. MOLECULAR & CELLULAR PROTEOMICS, 12(4), 921-931. doi:10.1074/mcp.M113.028878