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Patrick E. H. Jackson

Patrick E. H. Jackson

Associate Professor, Medicine- Infectious Diseases and International Health

Primary Location
PO Box 801340
Charlottesville, VA 22908
Primary Phone Number

Bio & Overview

Academic Information

Department
Medicine- Infectious Diseases and International Health

Primary Education

  • BA, Philosophy, Wake Forest University, 2006
  • MD, University of Virginia, 2010
  • Intern/ Resident, Internal Medicine, University of Virginia, 2013
  • Clinical Fellowship, Infectious Diseases, University of Virginia, 2016
  • Research Fellowship, Infectious Diseases, University of Virginia, 2017

Other Affiliations

  • BIMS

Research Interests

HIV virology

Research Disciplines

  • Infectious Diseases/Biodefense

Research Opportunities

  • Infectious Diseases

Selected Publications

2024

Chandrabhatla, A. S., Narahari, A. K., Horgan, T. M., Patel, P. D., Sturek, J. M., Davis, C. L., . . . Bell, T. D. (2024). Machine Learning-based Analysis of Publications Funded by the National Institutes of Health's Initial COVID-19 Pandemic Response. OPEN FORUM INFECTIOUS DISEASES, 11(4). doi:10.1093/ofid/ofae156

Narahari, A. K., Horgan, T. M., Chandrabhatla, A. S., Gist, D. C., Patel, P. D., Lantieri, M. A., . . . Bell, T. D. (2024). Analysis of National Institutes of Health Funding for the COVID-19 Pandemic. OPEN FORUM INFECTIOUS DISEASES, 11(3). doi:10.1093/ofid/ofae064

Hendrick, J., Ma, J. Z., Haughey, H. M., Coleman, R., Nayak, U., Kadl, A., . . . Petri, W. A. (2024). Pulmonary Function and Survival 1 Year After Dupilumab Treatment of Acute Moderate to Severe Coronavirus Disease 2019: A Follow-up Study From a Phase 2a Trial. OPEN FORUM INFECTIOUS DISEASES, 11(2). doi:10.1093/ofid/ofad630

2023

Jackson, P. E. H., Holsey, J., Turse, L., Hammarskjold, M. -L., & Rekosh, D. (2023). Rev-Rev Response Element Activity Selection Bias at the Human Immunodeficiency Virus Transmission Bottleneck. OPEN FORUM INFECTIOUS DISEASES, 10(10). doi:10.1093/ofid/ofad486

Hendrick, J., Ma, J., Haughey, H., Coleman, R., Nayak, U., Kadl, A., . . . Petri, W. (2023). Pulmonary function and survival one year after dupilumab treatment of acute moderate to severe COVID-19: A follow up study from a Phase IIa trial. doi:10.1101/2023.09.01.23293947

Zhu, B., Wei, X., Narasimhan, H., Qian, W., Zhang, R., Cheon, I. S., . . . Sun, J. (2023). Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19. SCIENCE IMMUNOLOGY, 8(82). doi:10.1126/sciimmunol.adf0348

Jackson, P. E. H., Holsey, J., Turse, L., Marie-Louise, H., & Rekosh, D. (2023). Rev-Rev Response Element Activity Selection Bias at the HIV Transmission Bottleneck.. bioRxiv. doi:10.1101/2023.04.05.535732

2022

Dzhivhuho, G., Holsey, J., Honeycutt, E., O'Farrell, H., Rekosh, D., Hammarskjold, M. -L., & Jackson, P. E. H. (2022). HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-21714-2

Sasson, J., Donlan, A. N., Ma, J. Z., Haughey, H. M., Coleman, R., Nayak, U., . . . Petri, W. A. J. (2022). Safety and Efficacy of Dupilumab for the Treatment of Hospitalized Patients With Moderate to Severe Coronavirus Disease 2019: A Phase 2a Trial. OPEN FORUM INFECTIOUS DISEASES, 9(8). doi:10.1093/ofid/ofac343

Sasson, J., Donlan, A. N., Ma, J. Z., Haughey, H. M., Coleman, R., Nayak, U., . . . Petri, W. A. (2022). Safety and Efficacy of Dupilumab for the Treatment of Hospitalized Patients with Moderate to Severe COVID 19: A Phase IIa Trial.. medRxiv. doi:10.1101/2022.03.30.22273194

2021

Kalil, A. C., Mehta, A. K., Patterson, T. F., Erdmann, N., Gomez, C. A., Jain, M. K., . . . Beigel, J. H. (2021). Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial. LANCET RESPIRATORY MEDICINE, 9(12), 1365-1376. doi:10.1016/S2213-2600(21)00384-2

2020

Kalil, A. C., Patterson, T. F., Mehta, A. K., Tomashek, K. M., Wolfe, C. R., Ghazaryan, V., . . . Beigel, J. H. (2021). Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19. NEW ENGLAND JOURNAL OF MEDICINE, 384(9), 795-807. doi:10.1056/NEJMoa2031994

Jackson, P. E. H., Dzhivhuho, G., Rekosh, D., & Hammarskjold, M. -L. (2020). Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis. CURRENT HIV RESEARCH, 18(2), 85-98. doi:10.2174/1570162X18666200106112842

2019

Gray, L. R., Jackson, R. E., Jackson, P. E. H., Bekiranov, S., Rekosh, D., & Hammarskjold, M. -L. (2019). HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA. RETROVIROLOGY, 16(1). doi:10.1186/s12977-019-0505-y

Sherpa, C., Jackson, P. E. H., Gray, L. R., Anastos, K., Le Grice, S. F. J., Hammarskjold, M. -L., & Rekosh, D. (2019). Evolution of the HIV-1 Rev Response Element during Natural Infection Reveals Nucleotide Changes That Correlate with Altered Structure and Increased Activity over Time. JOURNAL OF VIROLOGY, 93(11). doi:10.1128/JVI.02102-18

Jackson, P. E. H., Huang, J., Sharma, M., Rasmussen, S. K., Hammarskjold, M. -L., & Rekosh, D. (2019). A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-42914-3

2016

Jackson, P. E., Tebit, D. M., Rekosh, D., & Hammarskjold, M. -L. (2016). Rev-RRE Functional Activity Differs Substantially Among Primary HIV-1 Isolates. AIDS RESEARCH AND HUMAN RETROVIRUSES, 32(9), 923-934. doi:10.1089/aid.2016.0047

Liu, P., Jackson, P., Shaw, N., & Heysell, S. (2016). Spectrum of false positivity for the fourth generation human immunodeficiency virus diagnostic tests. AIDS RESEARCH AND THERAPY, 13. doi:10.1186/s12981-015-0086-3