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Patrick M. Dillon

Patrick M. Dillon

Professor of Medicine, Medicine- Hematology and Oncology

Primary Location
PO Box 800716
UVA Div. of Hematology & Oncology
Charlottesville, VA 22908
Primary Phone Number
Fax Number
434.244.7534

Bio & Overview

Dillon specializes in the treatment of breast and skin cancers. His current research focuses on immune modulation for treatment of human cancers. He also leads clinical trials of chemotherapeutic agents for the treatment of breast cancer. He promotes cancer survivorship issues and takes an interest in early and late term side effects of cancer treatments.

Academic Information

Department
Medicine- Hematology and Oncology

Primary Education

  • Clinical Fellowship, Hematology & Oncology, University of North Carolinanull
  • MD, University of North Carolina at Chapel Hillnull
  • Residency, Internal Medicine, University of Virginianull

Other Appointments

  • Medicine

Research Interests

Development of clinical trials in breast cancer; cancer immunotherapy; cancer survivorship improvement; cancer and aging.

Selected Publications

2024

Collis, R. W., Gee, A. J., Dillon, P., & Warwick, M. (2024). Slimmer's Palsy Following Weight Loss Associated With Metastatic Breast Cancer: A Case Report. CUREUS JOURNAL OF MEDICAL SCIENCE, 16(1). doi:10.7759/cureus.52519

Millard, T., Brenin, C., Humphrey, C., Dhakal, A., Falkson, C., Petroni, G., . . . Dillon, P. (2024). A Pilot Study of the Combination of Entinostat with Capecitabine in Advanced Breast Cancer. INTERNATIONAL JOURNAL OF BREAST CANCER, 2024. doi:10.1155/2024/5515966

2023

Tandon, M., Yacur, M., Brenin, C., & Dillon, P. (2024). Cryotherapy for prevention of chemotherapy induced peripheral neuropathy in breast cancer. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 194. doi:10.1016/j.critrevonc.2023.104244

Schlefman, J., Brenin, C., Millard, T., & Dillon, P. (2023). Estrogen receptor positive breast cancer: contemporary nuances to sequencing therapy. MEDICAL ONCOLOGY, 41(1). doi:10.1007/s12032-023-02255-8

Jusino, S., Fadul, C. E. E., & Dillon, P. (2023). Systematic review of the management of brain metastases from hormone receptor positive breast cancer. JOURNAL OF NEURO-ONCOLOGY, 162(1), 45-57. doi:10.1007/s11060-023-04276-9

Ladwa, A., Elghawy, O., Schroen, A., Abernathy, K., Schlefman, J., & Dillon, P. (2023). Complete Response of Triple-Negative Metaplastic Carcinoma of the Breast Using Pembrolizumab. CASE REPORTS IN ONCOLOGY, 16(1), 1129-1135. doi:10.1159/000534146

Kilmartin, C., Westover, C., Raghavan, S., Dillon, P. M., & Campbell, C. A. (2023). Desmoid Tumor and Implant-Based Breast Reconstruction. CASE REPORTS IN ONCOLOGY, 16(1), 74-80. doi:10.1159/000525350

2022

Morris, B. B., Smith, J. P., Zhang, Q., Jiang, Z., Hampton, O. A., Churchman, M. L., . . . Mayo, M. W. (2022). Replicative Instability Drives Cancer Progression. BIOMOLECULES, 12(11). doi:10.3390/biom12111570

Bidard, F. -C., Kaklamani, V. G., Neven, P., Streich, G., Montero, A. J., Forget, F., . . . Bardia, A. (2022). Elacestrant (oral selective estrogen receptor degrader) Versus Standard Endocrine Therapy for Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Results From the Randomized Phase III EMERALD Trial. JOURNAL OF CLINICAL ONCOLOGY, 40(28), 3246-+. doi:10.1200/JCO.22.00338

Harris, A. R., Esparza, S., Azimi, M. S., Cornelison, R., Azar, F. N., Llaneza, D. C., . . . Munson, J. M. (2022). Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy. FRONTIERS IN ONCOLOGY, 12. doi:10.3389/fonc.2022.801764

Mort, J., Maheshwari, S., Basu, N., Dillon, P., Brady, K., Bear, H., & Millard, T. (2022). A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim. CASE REPORTS IN ONCOLOGICAL MEDICINE, 2022. doi:10.1155/2022/7295305

2021

Dillon, P. M., Tushir-Singh, J., & Lum, L. G. (2022). Bispecific antibodies for the treatment of breast cancer. EXPERT OPINION ON BIOLOGICAL THERAPY, 22(8), 1017-1027. doi:10.1080/14712598.2021.1922665

Moore, M., Mills, A., Dillon, P., Atkins, K., & Shanes, E. (2021). Pleomorphic adenoma of the breast: A potential morphologic and molecular pitfall in the era of genomic risk stratification. CURRENT PROBLEMS IN CANCER: CASE REPORTS, 3. doi:10.1016/j.cpccr.2020.100047

Sytov, A., Brenin, C., Millard, T., Showalter, S., & Dillon, P. (2021). Long-Term Non-progression in Metastatic Breast Cancer Beyond 5 Years: Case Series and Review. CURRENT BREAST CANCER REPORTS, 13(3), 208-215. doi:10.1007/s12609-021-00410-6

Mariotti, V., Han, H., Ismail-Khan, R., Tang, S. J., Dillon, P., Montero, A. J., . . . Soliman, H. (2021). Effect of Taxane Chemotherapy With or Without Indoximod in Metastatic Breast Cancer A Randomized Clinical Trial. JAMA ONCOLOGY, 7(1), 61-69. doi:10.1001/jamaoncol.2020.5572

2020

Silvestre, J., Gosse, T., Read, P., Gentzler, R., Purow, B., Asthagiri, A., . . . Fadul, C. E. (2021). Genesis of Quality Measurements to Improve the Care Delivered to Patients With Brain Metastases. JCO ONCOLOGY PRACTICE, 17(3), 146-+. doi:10.1200/OP.20.00233

Wages, N. A., Millard, T. A., Dillon, P. M., Brenin, C. M., & Petroni, G. R. (2020). Efficient dose-finding for drug combination studies involving a shift in study populations. CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS, 17. doi:10.1016/j.conctc.2020.100519

Arora, P., Talamo, L., Dillon, P., Gentzler, R. D., Millard, T., Salerno, M., . . . Gaughan, E. M. (2020). Severe combined cardiac and neuromuscular toxicity from immune checkpoint blockade: an institutional case series. CARDIO-ONCOLOGY, 6(1). doi:10.1186/s40959-020-00076-6

Dillon, P. M., Brenin, C. M., & Slingluff, C. L. J. (2020). Evaluating Nelipepimut-S in the Treatment of Breast Cancer: A Short Report on the Emerging Data. BREAST CANCER-TARGETS AND THERAPY, 12, 69-75. doi:10.2147/BCTT.S224758

2019

Vinayak, S., Tolaney, S. M., Schwartzberg, L., Mita, M., McCann, G., Tan, A. R., . . . Telli, M. L. (2019). Open-label Clinical Trial of Niraparib Combined With Pembrolizumab for Treatment of Advanced or Metastatic Triple-Negative Breast Cancer. JAMA ONCOLOGY, 5(8), 1132-1140. doi:10.1001/jamaoncol.2019.1029

Thomas, M. H., Higgs, L. K., Modesitt, S. C., Schroen, A. T., Ring, K. L., & Dillon, P. M. (2019). Cases and evidence for panel testing in cancer genetics: Is site-specific testing dead?. JOURNAL OF GENETIC COUNSELING, 28(3), 700-707. doi:10.1002/jgc4.1044

Millard, T., Gupta, A., Brenin, C., Marshall, P., & Dillon, P. (2019). Radiographically Occult Carcinomatous Spread of Breast Cancer to the Liver: A Challenging Case. CASE REPORTS IN ONCOLOGICAL MEDICINE, 2019. doi:10.1155/2019/4935615

2018

Van Swearingen, A. E. D., Siegel, M. B., Deal, A. M., Sambade, M. J., Hoyle, A., Hayes, D. N., . . . Anders, C. K. (2018). LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases. BREAST CANCER RESEARCH AND TREATMENT, 171(3), 637-648. doi:10.1007/s10549-018-4852-5

Dill, E. A., Dillon, P. M., Bullock, T. N., & Mills, A. M. (2018). IDO expression in breast cancer: an assessment of 281 primary and metastatic cases with comparison to PD-L1. MODERN PATHOLOGY, 31(10), 1513-1522. doi:10.1038/s41379-018-0061-3

Mills, A. M., Dill, E. A., Moskaluk, C. A., Dziegielewski, J., Bullock, T. N., & Dillon, P. M. (2018). The Relationship Between Mismatch Repair Deficiency and PD-L1 Expression in Breast Carcinoma. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 42(2), 183-191. doi:10.1097/PAS.0000000000000949

2017

Kim, Y., Dillon, P. M., Park, T., & Lee, J. K. (2018). CONCORD biomarker prediction for novel drug introduction to different cancer types. ONCOTARGET, 9(1), 1091-1106. doi:10.18632/oncotarget.23124

Dillon, P. M., Petroni, G. R., Smolkin, M. E., Brenin, D. R., Chianese-Bullock, K. A., Smith, K. T., . . . Slingluff, C. L. J. (2017). A pilot study of the immunogenicity of a 9-peptide breast cancer vaccine plus poly-ICLC in early stage breast cancer. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 5. doi:10.1186/s40425-017-0295-5

Vernali, S., Waxweiler, W. T., Dillon, P. M., Kanetsky, P. A., Orlow, I., Luo, L., . . . Thomas, N. E. (2017). Association of Incident Amelanotic Melanoma With Phenotypic Characteristics, MC1R Status, and Prior Amelanotic Melanoma. JAMA DERMATOLOGY, 153(10), 1026-1031. doi:10.1001/jamadermatol.2017.2444

Jovanovic, B., Mayer, I. A., Mayer, E. L., Abramson, V. G., Bardia, A., Sanders, M. E., . . . Pietenpol, J. A. (2017). A Randomized Phase II Neoadjuvant Study of Cisplatin, Paclitaxel With or Without Everolimus in Patients with Stage II/III Triple-Negative Breast Cancer (TNBC): Responses and Long-term Outcome Correlated with Increased Frequency of DNA Damage Response Gene Mutations, TNBC Subtype, AR Status, and Ki67. CLINICAL CANCER RESEARCH, 23(15), 4035-4045. doi:10.1158/1078-0432.CCR-16-3055

Dill, E. A., Gru, A. A., Atkins, K. A., Friedman, L. A., Moore, M. E., Bullock, T. N., . . . Mills, A. M. (2017). PD-L1 Expression and Intratumoral Heterogeneity Across Breast Cancer Subtypes and Stages An Assessment of 245 Primary and 40 Metastatic Tumors. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 41(3), 334-342. doi:10.1097/PAS.0000000000000780

Romano, A. M., Gade, K. E., Nielsen, G., Havard, R., Harrison, J. H. J., Barclay, J., . . . Dillon, P. M. (2017). Early Palliative Care Reduces End-of-Life Intensive Care Unit (ICU) Use but Not ICU Course in Patients with Advanced Cancer. ONCOLOGIST, 22(3), 318-323. doi:10.1634/theoncologist.2016-0227

Dillon, P. M., Geroni, G. R., Horton, B. J., Moskaluk, C. A., Fracasso, P. M., Douvas, M. G., . . . Thomas, C. Y. (2017). A Phase II Study of Dovitinib in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma. Clinical Cancer Research, 23(15), 4138-4145. doi:10.1158/1078-0432.CCR-16-2942

Dillon, P. M., Petroni, G. R., Horton, B. J., Moskaluk, C. A., Fracasso, P. M., Douvas, M. G., . . . Thomas, C. Y. (2017). A Phase II Study of Dovitinib in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma. CLINICAL CANCER RESEARCH, 23(15), 4138-4145. doi:10.1158/1078-0432.CCR-16-2942

Martin, A. N., Dillon, P. M., Jones, D. E., Brenin, D. R., & Lapides, D. A. (2017). Anti-Yo Mediated Paraneoplastic Cerebellar Degeneration Associated with Pseudobulbar Affect in a Patient with Breast Cancer. CASE REPORTS IN ONCOLOGICAL MEDICINE, 2017. doi:10.1155/2017/8120689

2016

Fanous, I., & Dillon, P. (2016). Cancer treatment-related cardiac toxicity: prevention, assessment and management. MEDICAL ONCOLOGY, 33(8). doi:10.1007/s12032-016-0801-5

Hamirani, Y., Fanous, I., Kramer, C. M., Wong, A., Salerno, M., & Dillon, P. (2016). Anthracycline- and trastuzumab-induced cardiotoxicity: a retrospective study. MEDICAL ONCOLOGY, 33(7). doi:10.1007/s12032-016-0797-x

Pierson, T. M., Tebit, E. V., El Sayed, A., Smolkin, M. E., & Dillon, P. M. (2016). Orbital Metastases from Breast Cancer: Retrospective Analysis at an Academic Cancer Center. BREAST JOURNAL, 22(4), 447-450. doi:10.1111/tbj.12604

Gentzler, R., Hall, R., Kunk, P. R., Gaughan, E., Dillon, P., Slingluff, C. L. J., & Rahma, O. E. (2016). Beyond melanoma: inhibiting the PD-1/PDL-1 pathway in solid tumors. IMMUNOTHERAPY, 8(5), 583-600. doi:10.2217/imt-2015-0029

Winn, J. S., Baker, M. G., Fanous, I. S., Slack-Davis, J. K., Atkins, K. A., & Dillon, P. M. (2016). Lobular Breast Cancer and Abdominal Metastases: A Retrospective Review and Impact on Survival. ONCOLOGY, 91(3), 135-142. doi:10.1159/000447264

2015

Blackhall, L. J., Read, P., Stukenborg, G., Dillon, P., Barclay, J., Romano, A., & Harrison, J. (2016). CARE Track for Advanced Cancer: Impact and Timing of an Outpatient Palliative Care Clinic. JOURNAL OF PALLIATIVE MEDICINE, 19(1), 57-63. doi:10.1089/jpm.2015.0272

Joshi, P., Smolkin, M. E., & Dillon, P. (2016). Role of postoperative radiation therapy in patients with adenoid cystic carcinoma: a SEER analysis. JOURNAL OF RADIATION ONCOLOGY, 5(2), 153-159. doi:10.1007/s13566-015-0234-3

Stukenborg, G. J., Blackhall, L. J., Harrison, J. H., Dillon, P. M., & Read, P. W. (2016). Longitudinal patterns of cancer patient reported outcomes in end of life care predict survival. SUPPORTIVE CARE IN CANCER, 24(5), 2217-2224. doi:10.1007/s00520-015-3024-y

Dillon, P. M., Chakraborty, S., Moskaluk, C. A., Joshi, P. J., & Thomas, C. Y. (2016). Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 38(4), 620-627. doi:10.1002/hed.23925

Fanous, I., & Dillon, P. (2016). Paraneoplastic neurological complications of breast cancer. EXPERIMENTAL HEMATOLGY & ONCOLOGY, 5. doi:10.1186/s40164-016-0058-x

Romano, A. M., Wages, N. A., Smolkin, M., Fortune, K. L., Atkins, K., & Dillon, P. M. (2015). Tubular carcinoma of the breast: institutional and SEER database analysis supporting a unique classification.. Breast disease, 35(2), 103-111. doi:10.3233/bd-140396

2014

Thomas, N. E., Kricker, A., Waxweiler, W. T., Dillon, P. M., Busam, K. J., From, L., . . . Berwick, M. (2014). Comparison of Clinicopathologic Features and Survival of Histopathologically Amelanotic and Pigmented Melanomas A Population-Based Study. JAMA DERMATOLOGY, 150(12), 1306-1314. doi:10.1001/jamadermatol.2014.1348

Sanoff, H. K., Deal, A. M., Krishnamurthy, J., Torrice, C., Dillon, P., Sorrentino, J., . . . Muss, H. B. (2014). Effect of Cytotoxic Chemotherapy on Markers of Molecular Age in Patients With Breast Cancer. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 106(4). doi:10.1093/jnci/dju057

Dillon, P. M., Olson, W. C., Czarkowski, A., Petroni, G. R., Smolkin, M., Grosh, W. W., . . . Slingluff, C. L. J. (2014). A melanoma helper peptide vaccine increases Th1 cytokine production by leukocytes in peripheral blood and immunized lymph nodes. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2. doi:10.1186/2051-1426-2-23

2013

Stukenborg, G. J., Blackhall, L., Harrison, J., Barclay, J. S., Dillon, P., Davis, M. A., . . . Read, P. (2014). Cancer patient-reported outcomes assessment using wireless touch screen tablet computers. QUALITY OF LIFE RESEARCH, 23(5), 1603-1607. doi:10.1007/s11136-013-0595-2

Marchetti, M. A., Noland, M. M., Dillon, P. M., & Greer, K. E. (2013). Taxane associated subacute cutaneous lupus erythematosus.. Dermatology online journal, 19(8), 19259.

2012

Roberts, P. J., Usary, J. E., Darr, D. B., Dillon, P. M., Pfefferle, A. D., Whittle, M. C., . . . Sharpless, N. E. (2012). Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models. CLINICAL CANCER RESEARCH, 18(19), 5290-5303. doi:10.1158/1078-0432.CCR-12-0563

Combest, A. J., Roberts, P. J., Dillon, P. M., Sandison, K., Hanna, S. K., Ross, C., . . . Zamboni, W. C. (2012). Genetically Engineered Cancer Models, But Not Xenografts, Faithfully Predict Anticancer Drug Exposure in Melanoma Tumors. ONCOLOGIST, 17(10), 1303-1316. doi:10.1634/theoncologist.2012-0274

Pritchard, J. E., Dillon, P. M., Conaway, M. R., Silva, C. M., & Parsons, S. J. (2012). A Mechanistic Study of the Effect of Doxorubicin/Adriamycin on the Estrogen Response in a Breast Cancer Model. ONCOLOGY, 83(6), 305-320. doi:10.1159/000341394

2010

Song, Z., von Figura, G., Liu, Y., Kraus, J. M., Torrice, C., Dillon, P., . . . Rudolph, K. L. (2010). Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood. AGING CELL, 9(4), 607-615. doi:10.1111/j.1474-9726.2010.00583.x