Suna Onengut-Gumuscu

Triolo, T. M., Parikh, H. M., Tosur, M., Ferrat, L. A., You, L., Gottlieb, P. A., . . . Redondo, M. J. (2024). Genetic Associations With C-peptide Levels Before Type 1 Diabetes Diagnosis in At-risk Relatives. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. doi:10.1210/clinem/dgae349

Felton, J. L., Redondo, M. J., Oram, R. A., Speake, C., Long, S. A., Onengut-Gumuscu, S., . . . Franks, P. W. (2024). Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review. COMMUNICATIONS MEDICINE, 4(1). doi:10.1038/s43856-024-00478-y

Felton, J. L., Griffin, K. J., Oram, R. A., Speake, C., Long, S. A., Onengut-Gumuscu, S., . . . Sims, E. K. (2023). Disease-modifying therapies and features linked to treatment response in type 1 diabetes prevention: a systematic review. COMMUNICATIONS MEDICINE, 3(1). doi:10.1038/s43856-023-00357-y

Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., . . . Franks, P. W. (2023). Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine. NATURE MEDICINE, 29(10), 2438-2457. doi:10.1038/s41591-023-02502-5

Newman, J. R. B., Long, S. A., Speake, C., Greenbaum, C. J., Cerosaletti, K., Rich, S. S., . . . Concannon, P. (2023). Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes. COMMUNICATIONS BIOLOGY, 6(1). doi:10.1038/s42003-023-05327-7

Onengut-Gumuscu, S., Webb-Robertson, B. -J. M., Sarkar, S., Manichaikul, A., Hu, X., Frazer-Abel, A., . . . Rich, S. S. (2024). Genetic variants in the complement system and their potential link in the aetiology of type 1 diabetes. DIABETES-METABOLISM RESEARCH AND REVIEWS, 40(1). doi:10.1002/dmrr.3716

Miller, R. G., Mychaleckyj, J. C., Onengut-Gumuscu, S., Feingold, E., Orchard, T. J., & Costacou, T. (2023). DNA methylation and 28-year cardiovascular disease risk in type 1 diabetes: the Epidemiology of Diabetes Complications (EDC) cohort study. CLINICAL EPIGENETICS, 15(1). doi:10.1186/s13148-023-01539-0

Kudtarkar, P., Costanzo, M. C., Sun, Y., Jang, D., Koesterer, R., Mychaleckyj, J. C., . . . Burtt, N. P. (2023). Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal. PLOS BIOLOGY, 21(8). doi:10.1371/journal.pbio.3002233

Dillard, L. J., Rosenow, W. T., Calabrese, G. M., Mesner, L. D., Al-Barghouthi, B. M., Abood, A., . . . Farber, C. R. (2023). Single-Cell Transcriptomics of Bone Marrow Stromal Cells in Diversity Outbred Mice: A Model for Population-Level scRNA-Seq Studies. JOURNAL OF BONE AND MINERAL RESEARCH, 38(9), 1350-1363. doi:10.1002/jbmr.4882

Buckner, T., Johnson, R. K., Vanderlinden, L. A., Carry, P. M., Romero, A., Onengut-Gumuscu, S., . . . Norris, J. M. (2023). An Oxylipin-Related Nutrient Pattern and Risk of Type 1 Diabetes in the Diabetes Autoimmunity Study in the Young (DAISY). NUTRIENTS, 15(4). doi:10.3390/nu15040945

Buckner, T., Johnson, R. K., Vanderlinden, L. A., Carry, P. M., Romero, A., Onengut-Gumuscu, S., . . . Norris, J. M. (2023). Genome-wide analysis of oxylipins and oxylipin profiles in a pediatric population. FRONTIERS IN NUTRITION, 10. doi:10.3389/fnut.2023.1040993

Michalek, D. A., Onengut-Gumuscu, S., Repaske, D. R., & Rich, S. S. (2023). Precision Medicine in Type 1 Diabetes. JOURNAL OF THE INDIAN INSTITUTE OF SCIENCE, 103(1), 335-351. doi:10.1007/s41745-023-00356-x

Miller, R. G., Mychaleckyj, J. C., Onengut-Gumuscu, S., Orchard, T. J., & Costacou, T. (2023). TXNIP DNA methylation is associated with glycemic control over 28 years in type 1 diabetes: findings from the Pittsburgh Epidemiology of Diabetes Complications (EDC) study. BMJ OPEN DIABETES RESEARCH & CARE, 11(1). doi:10.1136/bmjdrc-2022-003068

Turner, A. W., Hu, S. S., Mosquera, J. V., Ma, W. F., Hodonsky, C. J., Wong, D., . . . Miller, C. L. (2022). Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk (vol 54, pg 804, 2022). NATURE GENETICS, 54(8), 1259. doi:10.1038/s41588-022-01142-8

Redondo, M. J., Gignoux, C. R., Dabelea, D., Hagopian, W. A., Onengut-Gumuscu, S., Oram, R. A., & Rich, S. S. (2022). Type 1 diabetes in diverse ancestries and the use of genetic risk scores. LANCET DIABETES & ENDOCRINOLOGY, 10(8), 597-608. doi:10.1016/S2213-8587(22)00159-0

Turner, A. W., Hu, S. S., Mosquera, J. V., Ma, W. F., Hodonsky, C. J., Wong, D., . . . Miller, C. L. (2022). Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk. NATURE GENETICS, 54(6), 804-+. doi:10.1038/s41588-022-01069-0

Lucas, C. D., Medina, C. B., Bruton, F. A., Dorward, D. A., Raymond, M. H., Tufan, T., . . . Ravichandran, K. S. (2022). Pannexin 1 drives efficient epithelial repair after tissue injury. SCIENCE IMMUNOLOGY, 7(71). doi:10.1126/sciimmunol.abm4032

Torn, C., Liu, X., Onengut-Gumuscu, S., Counts, K. M., Moreno, J. L., Remedios, C. L., . . . Parikh, H. M. (2022). Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-08058-7

Braenne, I., Onengut-Gumuscu, S., Chen, R., Manichaikul, A. W., Rich, S. S., Chen, W. -M., & Farber, C. R. (2021). Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-01840-z

Arandjelovic, S., Perry, J. S. A., Zhou, M., Ceroi, A., Smirnov, I., Walk, S. F., . . . Ravichandran, K. S. (2021). ELMO1 signaling is a promoter of osteoclast function and bone loss. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-25239-6

Mychaleckyj, J. C., Valo, E., Ichimura, T., Ahluwalia, T. S., Dina, C., Miller, R. G., . . . Krolewski, A. S. (2021). Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 32(10), 2634-2651. doi:10.1681/ASN.2020101457

Robertson, C. C., Inshaw, J. R. J., Onengut-Gumuscu, S., Chen, W. -M., Santa Cruz, D. F., Yang, H., . . . Rich, S. S. (2021). Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. NATURE GENETICS, 53(7), 962-+. doi:10.1038/s41588-021-00880-5

Al-Barghouthi, B. M., Mesner, L. D., Calabrese, G. M., Brooks, D., Tommasini, S. M., Bouxsein, M. L., . . . Farber, C. R. (2021). Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-23649-0

Da Mesquita, S., Papadopoulos, Z., Dykstra, T., Brase, L., Farias, F. G., Wall, M., . . . Kipnis, J. (2021). Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy. NATURE, 593(7858), 255-+. doi:10.1038/s41586-021-03489-0

Olson, T. L., Cheon, H., Xing, J. C., Olson, K. C., Paila, U., Hamele, C. E., . . . Loughran, T. P. J. (2021). Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias. BLOOD, 138(8), 662-673. doi:10.1182/blood.2020005831

Miller, R. G., Orchard, T. J., Onengut-Gumuscu, S., Chen, W. -M., Rich, S. S., & Costacou, T. (2021). Heterogeneous long-term trajectories of glycaemic control in type 1 diabetes. DIABETIC MEDICINE, 38(8). doi:10.1111/dme.14545

Bonifacio, E., Weiß, A., Winkler, C., Hippich, M., Rewers, M. J., Toppari, J., . . . TEDDY Study Group. (2021). An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood.. Diabetes care, dc202122. doi:10.2337/dc20-2122

Miller, R. G., McGurnaghan, S. J., Onengut-Gumuscu, S., Chen, W. -M., Colhoun, H. M., Rich, S. S., . . . Costacou, T. (2021). Insulin resistance-associated genetic variants in type 1 diabetes. JOURNAL OF DIABETES AND ITS COMPLICATIONS, 35(4). doi:10.1016/j.jdiacomp.2020.107842

Tran, P. M. H., Purohit, S., Kim, E., bin Satter, K., Hopkins, D., Waugh, K., . . . She, J. -X. (2021). The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway. JOURNAL OF TRANSLATIONAL AUTOIMMUNITY, 4. doi:10.1016/j.jtauto.2021.100127

Laker, R. C., Altintas, A., Lillard, T. S., Zhang, M., Connelly, J. J., Sabik, O. L., . . . Yan, Z. (2021). Exercise during pregnancy mitigates negative effects of parental obesity on metabolic function in adult mouse offspring. JOURNAL OF APPLIED PHYSIOLOGY, 130(3), 605-616. doi:10.1152/japplphysiol.00641.2020

Onengut-Gumuscu, S., Paila, U., Chen, W. -M., Ratan, A., Zhu, Z., Steck, A. K., . . . Rich, S. S. (2020). Novel genetic risk factors influence progression of islet autoimmunity to type 1 diabetes. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-75690-6

Sidore, C., Orru, V., Cocco, E., Steri, M., Inshaw, J. R. J., Pitzalis, M., . . . Zoledziewska, M. (2021). PRF1 mutation alters immune system activation, inflammation, and risk of autoimmunity. MULTIPLE SCLEROSIS JOURNAL, 27(9), 1332-1340. doi:10.1177/1352458520963937

Aherrahrou, R., Guo, L., Nagraj, V. P., Aguhob, A., Hinkle, J., Chen, L., . . . Civelek, M. (2020). Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells. CIRCULATION RESEARCH, 127(12), 1552-1565. doi:10.1161/CIRCRESAHA.120.317415

Vehik, K., Bonifacio, E., Lernmark, Å., Yu, L., Williams, A., Schatz, D., . . . TEDDY Study Group. (2020). Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study.. Diabetes care, 43(9), 2066-2073. doi:10.2337/dc19-2547

Cui, D., Drake, J. C., Wilson, R. J., Shute, R. J., Lewellen, B., Zhang, M., . . . Yan, Z. (2020). A novel voluntary weightlifting model in mice promotes muscle adaptation and insulin sensitivity with simultaneous enhancement of autophagy and mTOR pathway. FASEB JOURNAL, 34(6), 7330-7344. doi:10.1096/fj.201903055R

Li, Q., Parikh, H., Butterworth, M. D., Lernmark, A., Hagopian, W., Rewers, M., . . . Krischer, J. P. (2020). Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study. DIABETES, 69(3), 465-476. doi:10.2337/db19-0756

Wang, T. T., Yang, J., Dighe, S., Schmachtenberg, M. W., Leigh, N. T., Farber, E., . . . Olson, T. L. (2020). Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation. CANCERS, 12(1). doi:10.3390/cancers12010126

Liu, X., Vehik, K., Huang, Y., Elding Larsson, H., Toppari, J., Ziegler, A. G., . . . TEDDY Study Group. (2020). Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study.. Diabetes care, 43(3), 556-562. doi:10.2337/dc19-1670

Perry, J. S. A., Morioka, S., Medina, C. B., Etchegaray, J. I., Barron, B., Raymond, M. H., . . . Ravichandran, K. S. (2019). Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway. NATURE CELL BIOLOGY, 21(12), 1532-+. doi:10.1038/s41556-019-0431-1

Fernandez-Castaneda, A., Chappell, M. S., Rosen, D. A., Seki, S. M., Beiter, R. M., Johanson, D. M., . . . Gaultier, A. (2020). The active contribution of OPCs to neuroinflammation is mediated by LRP1. ACTA NEUROPATHOLOGICA, 139(2), 365-382. doi:10.1007/s00401-019-02073-1

Salem, R. M., Todd, J. N., Sandholm, N., Cole, J. B., Chen, W. -M., Andrews, D., . . . Florez, J. C. (2019). Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 30(10), 2000-2016. doi:10.1681/ASN.2019030218

Krischer, J. P., Liu, X., Vehik, K., Akolkar, B., Hagopian, W. A., Rewers, M. J., . . . TEDDY Study Group. (2019). Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report.. Diabetes care, 42(6), 1051-1060. doi:10.2337/dc18-2282

Singh, S., Wang, L., Schaff, D. L., Sutcliffe, M. D., Koeppel, A. F., Kim, J., . . . Janes, K. A. (2019). In situ 10-cell RNA sequencing in tissue and tumor biopsy samples. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-41235-9

Jacobsen, L. M., Larsson, H. E., Tamura, R. N., Vehik, K., Clasen, J., Sosenko, J., . . . Triplett, E. (2019). Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children. PEDIATRIC DIABETES, 20(3), 263-270. doi:10.1111/pedi.12812

Onengut-Gumuscu, S., Chen, W. -M., Robertson, C. C., Bonnie, J. K., Farber, E., Zhu, Z., . . . Rich, S. S. (2019). Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score. DIABETES CARE, 42(3), 406-415. doi:10.2337/dc18-1727

Hippich, M., Beyerlein, A., Hagopian, W. A., Krischer, J. P., Vehik, K., Knoop, J., . . . Ziegler, A. -G. (2019). Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families. DIABETES, 68(4), 847-857. doi:10.2337/db18-0882

Marquez, A., Kerick, M., Zhernakova, A., Gutierrez-Achury, J., Chen, W. -M., Onengut-Gumuscu, S., . . . Martin, J. (2018). Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations. GENOME MEDICINE, 10. doi:10.1186/s13073-018-0604-8

Da Mesquita, S., Louveau, A., Vaccari, A., Smirnov, I., Cornelison, R. C., Kingsmore, K. M., . . . Kipnis, J. (2018). Publisher Correction: Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.. Nature, 564(7734), E7. doi:10.1038/s41586-018-0689-7

Morioka, S., Perry, J. S. A., Raymond, M. H., Medina, C. B., Zhu, Y., Zhao, L., . . . Ravichandran, K. S. (2018). Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. NATURE, 563(7733), 714-718. doi:10.1038/s41586-018-0735-5

Rewers, M., Hyoty, H., Lernmark, A., Hagopian, W., She, J. -X., Schatz, D., . . . Krischer, J. (2018). The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update. CURRENT DIABETES REPORTS, 18(12). doi:10.1007/s11892-018-1113-2

Westra, H. -J., Martinez-Bonet, M., Onengut-Gumuscu, S., Lee, A., Luol, Y., Teslovich, N., . . . Raychaudhuri, S. (2018). Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. NATURE GENETICS, 50(10), 1366-+. doi:10.1038/s41588-018-0216-7

Da Mesquita, S., Louveau, A., Vaccari, A., Smirnov, I., Cornelison, R. C., Kingsmore, K. M., . . . Kipnis, J. (2018). Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. NATURE, 560(7717), 185-+. doi:10.1038/s41586-018-0368-8

Sharma, A., Liu, X., Hadley, D., Hagopian, W., Chen, W. -M., Onengut-Gumuscu, S., . . . She, J. -X. (2018). Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort. JOURNAL OF AUTOIMMUNITY, 89, 90-100. doi:10.1016/j.jaut.2017.12.008

Penberthy, K. K., Rival, C., Shankman, L. S., Raymond, M. H., Zhang, J., Perry, J. S. A., . . . Ravichandran, K. S. (2017). Context-dependent compensation among phosphatidylserine-recognition receptors. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-15191-1

Shi, Y., Stornetta, R. L., Stornetta, D. S., Onengut-Gumuscu, S., Farber, E. A., Turner, S. D., . . . Bayliss, D. A. (2017). Neuromedin B Expression Defines the Mouse Retrotrapezoid Nucleus. JOURNAL OF NEUROSCIENCE, 37(48), 11744-11757. doi:10.1523/JNEUROSCI.2055-17.2017

Norris, J. M., Lee, H. -S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., . . . Hagopian, W. (2018). Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity. DIABETES, 67(1), 146-154. doi:10.2337/db17-0802

Newman, J. R. B., Conesa, A., Mika, M., New, F. N., Onengut-Gumuscu, S., Atkinson, M. A., . . . Concannon, P. (2017). Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes. GENOME RESEARCH, 27(11), 1807-1815. doi:10.1101/gr.217984.116

Manichaikul, A., Wang, X. -Q., Sun, L., Dupuis, J., Borczuk, A. C., Nguyen, J. N., . . . Lederer, D. J. (2017). Genome-wide association study of subclinical interstitial lung disease in MESA. RESPIRATORY RESEARCH, 18. doi:10.1186/s12931-017-0581-2

Steck, A. K., Xu, P., Geyer, S., Redondo, M. J., Antinozzi, P., Wentworth, J. M., . . . Pugliese, A. (2017). Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes?. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 102(8), 2873-2880. doi:10.1210/jc.2016-4003

Lundgren, M., Steed, L. J., Tamura, R., Jonsdottir, B., Gesualdo, P., Crouch, C., . . . Larsson, H. E. (2017). Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity. BMC PEDIATRICS, 17. doi:10.1186/s12887-017-0884-y

Manichaikul, A., Sun, L., Borczuk, A. C., Onengut-Gumuscu, S., Farber, E. A., Mathai, S. K., . . . Lederer, D. J. (2017). Plasma Soluble Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis. ANNALS OF THE AMERICAN THORACIC SOCIETY, 14(5), 628-635. doi:10.1513/AnnalsATS.201606-485OC

Marin, I. A., Goertz, J. E., Ren, T., Rich, S. S., Onengut-Gumuscu, S., Farber, E., . . . Gaultier, A. (2017). Microbiota alteration is associated with the development of stress-induced despair behavior. SCIENTIFIC REPORTS, 7. doi:10.1038/srep43859

Han, C. Z., Juncadella, I. J., Kinchen, J. M., Buckley, M. W., Klibanov, A. L., Dryden, K., . . . Ravichandran, K. S. (2016). Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation. NATURE, 539(7630), 570-+. doi:10.1038/nature20141

Torn, C., Liu, X., Hagopian, W., Lernmark, A., Simell, O., Rewers, M., . . . Krischer, J. (2016). Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study. SCIENTIFIC REPORTS, 6. doi:10.1038/srep27887

Han, B., Pouget, J. G., Slowikowski, K., Stahl, E., Lee, C. H., Diogo, D., . . . Raychaudhuri, S. (2016). A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. NATURE GENETICS, 48(7), 803-+. doi:10.1038/ng.3572

Uusitalo, U., Liu, X., Yang, J., Aronsson, C. A., Hummel, S., Butterworth, M., . . . Virtanen, S. M. (2016). Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study. JAMA PEDIATRICS, 170(1), 20-28. doi:10.1001/jamapediatrics.2015.2757

Sharma, A., Liu, X., Hadley, D., Hagopian, W., Liu, E., Chen, W. -M., . . . She, J. -X. (2016). Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort. PLOS ONE, 11(3). doi:10.1371/journal.pone.0152476

Ge, Y., Onengut-Gumuscu, S., Quinlan, A. R., Mackey, A. J., Wright, J. A., Buckner, J. H., . . . Concannon, P. (2016). Targeted Deep Sequencing in Multiple-Affected Sibships of European Ancestry Identifies Rare Deleterious Variants in PTPN22 That Confer Risk for Type 1 Diabetes. DIABETES, 65(3), 794-802. doi:10.2337/db15-0322

Wang, Q., Grainger, A. T., Manichaikul, A., Farber, E., Onengut-Gumuscu, S., & Shi, W. (2015). Genetic linkage of hyperglycemia and dyslipidemia in an intercross between BALB/cJ and SM/J Apoe-deficient mouse strains. BMC GENETICS, 16. doi:10.1186/s12863-015-0292-y

Keating, B. J., van Setten, J., Jacobson, P. A., Holmes, M. V., Verma, S. S., Chandrupatla, H. R., . . . Asselbergs, F. W. (2015). Design and Implementation of the International Genetics and Translational Research in Transplantation Network. TRANSPLANTATION, 99(11), 2401-2412. doi:10.1097/TP.0000000000000913

Gutierrez-Achury, J., Romanos, J., Bakker, S. F., Kumar, V., de Haas, E. C., Trynka, G., . . . Wijmenga, C. (2015). Contrasting the Genetic Background of Type 1 Diabetes and Celiac Disease Autoimmunity. DIABETES CARE, 38, S37-S44. doi:10.2337/dcs15-2007

Lenz, T. L., Deutsch, A. J., Han, B., Hu, X., Okada, Y., Eyre, S., . . . Raychaudhuri, S. (2015). Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases. NATURE GENETICS, 47(9), 1085-+. doi:10.1038/ng.3379

Hu, X., Deutsch, A. J., Lenz, T. L., Onengut-Gumuscu, S., Han, B., Chen, W. -M., . . . Raychaudhuri, S. (2015). Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk. NATURE GENETICS, 47(8), 898-+. doi:10.1038/ng.3353

Wallace, C., Cutler, A. J., Pontikos, N., Pekalski, M. L., Burren, O. S., Cooper, J. D., . . . Wicker, L. S. (2015). Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping. PLOS GENETICS, 11(6). doi:10.1371/journal.pgen.1005272

Hadley, D., Hagopian, W., Liu, E., She, J. -X., Simell, O., Akolkar, B., . . . Agardh, D. (2015). HLA-DPB1^☆04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study. AMERICAN JOURNAL OF GASTROENTEROLOGY, 110(6), 915-920. doi:10.1038/ajg.2015.150

Furman, D., Jojic, V., Sharma, S., Shen-Orr, S. S., Angel, C. J. L., Onengut-Gumuscu, S., . . . Davis, M. M. (2015). Cytomegalovirus infection enhances the immune response to influenza. SCIENCE TRANSLATIONAL MEDICINE, 7(281). doi:10.1126/scitranslmed.aaa2293

Brorsson, C. A., Onengut, S., Chen, W. -M., Wenzlau, J., Yu, L., Baker, P., . . . Pociot, F. (2015). Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes. DIABETES, 64(8), 3017-3027. doi:10.2337/db14-1730

Isobe, N., Madireddy, L., Khankhanian, P., Matsushita, T., Caillier, S. J., More, J. M., . . . Oksenberg, J. R. (2015). An ImmunoChip study of multiple sclerosis risk in African Americans. BRAIN, 138, 1518-1530. doi:10.1093/brain/awv078

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