Todd Fox

Ohya, Y., Ogiso, Y., Matsuda, M., Sakae, H., Nishida, K., Miki, Y., . . . Kitatani, K. (2024). Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells. CELLS, 13(5). doi:10.3390/cells13050405

Ung, J., Tan, S. -F., Fox, T. E., Shaw, J. J. P., Taori, M., Horton, B. J., . . . Feith, D. J. (2023). Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. CANCERS, 15(24). doi:10.3390/cancers15245866

Thim, E. A., Fox, T., Deering, T., Vass, L. R., Sheybani, N. D., Kester, M., & Price, R. J. (2023). Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound.. bioRxiv. doi:10.1101/2023.03.23.532394

Fisher-Wellman, K. H., Kassai, M., Hagen, J. T., Neufer, P. D., Kester, M., Loughran Jr., T. P., . . . Cabot, M. C. (2023). Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia. CANCERS, 15(6). doi:10.3390/cancers15061883

Sakae, H., Ogiso, Y., Matsuda, M., Shimora, H., Deering, T., Fox, T. E., . . . Kitatani, K. (2023). Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma. CELLS, 12(4). doi:10.3390/cells12040591

Ung, J., Tan, S. -F., Shaw, J., Fox, T., Kester, M., Feith, D., & Loughran, T. J. (2022). Superior Anti-Leukemic Effects of Combined Acid Ceramidase and Bcl-2 Inhibition in Acute Myeloid Leukemia. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 22, S211-S212. Retrieved from https://www.webofscience.com/

Khokhlatchev, A. V., Sharma, A., Deering, T. G., Shaw, J. J. P., Costa-Pinheiro, P., Golla, U., . . . Kester, M. (2022). Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia. FASEB JOURNAL, 36(10). doi:10.1096/fj.202200765R

DiPasquale, M., Deering, T. G., Desai, D., Sharma, A. K., Amin, S., Fox, T. E., . . . Heberle, F. A. (2022). Influence of ceramide on lipid domain stability studied with small-angle neutron scattering: The role of acyl chain length and unsaturation. CHEMISTRY AND PHYSICS OF LIPIDS, 245. doi:10.1016/j.chemphyslip.2022.105205

Ung, J., Tan, S. -F., Fox, T. E., Shaw, J. J. P., Vass, L. R., Costa-Pinheiro, P., . . . Loughran, T. P. (2022). Harnessing the power of sphingolipids: Prospects for acute myeloid leukemia. BLOOD REVIEWS, 55. doi:10.1016/j.blre.2022.100950

Qi, X., Wu, F., Kim, S. H., Kaifi, J. T., Kimchi, E. T., Snyder, H., . . . Li, G. (2022). Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer. FASEB JOURNAL, 36(4). doi:10.1096/fj.202101707R

Salotto, K. E., Olson, W. C. J., Pollack, K. E., Illendula, A., Michel, E., Henriques, S., . . . Snyder, H. W. (2022). A nano-enhanced vaccine for metastatic melanoma immunotherapy. CANCER DRUG RESISTANCE, 5(3), 829-845. doi:10.20517/cdr.2021.132

LeBlanc, F. R., Hasanali, Z. S., Stuart, A., Shimko, S., Sharma, K., Leshchenko, V. V., . . . Epner, E. M. (2022). Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma.. Oncotarget, 13, 986-1002. doi:10.18632/oncotarget.28258

Fisher-Wellman, K. H., Hagen, J. T., Kassai, M., Kao, L. -P., Nelson, M. A. M., McLaughlin, K. L., . . . Cabot, M. C. (2022). Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia. FASEB JOURNAL, 36(1). doi:10.1096/fj.202101194RRR

Costa-Pinheiro, P., Heher, A., Raymond, M. H., Jividen, K., Shaw, J. J. P., Paschal, B. M., . . . Kester, M. (2020). Role of SPTSSB-Regulated de Novo Sphingolipid Synthesis in Prostate Cancer Depends on Androgen Receptor Signaling. ISCIENCE, 23(12). doi:10.1016/j.isci.2020.101855

Shaw, J. J. P., Boyer, T. L., Venner, E., Beck, P. J., Slamowitz, T., Caste, T., . . . Kester, M. (2020). Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome-Induced Cell Death in Head and Neck Squamous Cell Carcinoma. MOLECULAR CANCER THERAPEUTICS, 19(12), 2621-2633. doi:10.1158/1535-7163.MCT-20-0182

Patterson, L., Allen, J., Posey, I., Shaw, J. J. P., Costa-Pinheiro, P., Walker, S. J., . . . Kester, M. (2020). Glucosylceramide production maintains colon integrity in response toBacteroides fragilistoxin-induced colon epithelial cell signaling. FASEB JOURNAL, 34(12), 15922-15945. doi:10.1096/fj.202001669R

Bories, G. F. P., Yeudall, S., Serbulea, V., Fox, T. E., Isakson, B. E., & Leitinger, N. (2020). Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway. BLOOD, 136(13), 1535-1548. doi:10.1182/blood.2020004964

Keppley, L. J. W., Walker, S. J., Gademsey, A. N., Smith, J. P., Keller, S. R., Kester, M., & Fox, T. E. (2020). Nervonic acid limits weight gain in a mouse model of diet-induced obesity. FASEB JOURNAL, 34(11), 15314-15326. doi:10.1096/fj.202000525R

Olson, K. C., Moosic, K. B., Jones, M. K., Larkin, P. M. K., Olson, T. L., Toro, M. F., . . . Loughran, T. P. J. (2020). Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations. CANCER MEDICINE, 9(18), 6533-6549. doi:10.1002/cam4.3246

Zanieri, F., Levi, A., Montefusco, D., Longato, L., De Chiara, F., Frenguelli, L., . . . Rombouts, K. (2020). Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH. CELLS, 9(5). doi:10.3390/cells9051237

Drews, K., Calgi, M. P., Harrison, W. C., Drews, C. M., Costa-Pinheiro, P., Shaw, J. J. P., . . . Kester, M. (2020). Glucosylceramide synthase maintains influenza virus entry and infection. PLOS ONE, 15(2). doi:10.1371/journal.pone.0228735

Pearson, J. M., Tan, S. -F., Sharma, A., Annageldiyev, C., Fox, T. E., Abad, J. L., . . . Loughran, T. P. (2020). Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid Leukemia. MOLECULAR CANCER RESEARCH, 18(3), 352-363. doi:10.1158/1541-7786.MCR-19-0619

Barth, B. M., Wang, W., Toran, P. T., Fox, T. E., Annageldiyev, C., Ondrasik, R. M., . . . Claxton, D. F. (2019). Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia. BLOOD ADVANCES, 3(17), 2598-2603. doi:10.1182/bloodadvances.2018021295

Moore, J. H., Varhue, W. B., Su, Y. -H., Linton, S. S., Farmehini, V., Fox, D. E., . . . Swami, N. S. (2019). Conductance-Based Biophysical Distinction and Microfluidic Enrichment of Nanovesicles Derived from Pancreatic Tumor Cells of Varying Invasiveness. ANALYTICAL CHEMISTRY, 91(16), 10424-10431. doi:10.1021/acs.analchem.8b05745

Kao, L. -P., Morad, S. A. F., Davis, T. S., MacDougall, M. R., Kassai, M., Abdelmageed, N., . . . Cabot, M. C. (2019). Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells. JOURNAL OF LIPID RESEARCH, 60(9), 1590-1602. doi:10.1194/jlr.RA119000251

Ramakrishnan, G., Perez, N. M., Carroll, C., Moore, M. M., Nakarnoto, R. K., & Fox, T. E. (2019). Citryl Ornithine Is an Intermediate in a Three-Step Biosynthetic Pathway for Rhizoferrin in Francisella. ACS CHEMICAL BIOLOGY, 14(8), 1760-1766. doi:10.1021/acschembio.9b00297

Drews, K., Calgi, M. P., Harrison, W. C., Drews, C. M., Costa-Pinheiro, P., Shaw, J. J. P., . . . Kester, M. (2019). Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis. JOURNAL OF VIROLOGY, 93(12). doi:10.1128/JVI.00017-19

Moreau, G. B., Ramakrishnan, G., Cook, H. L., Fox, T. E., Nayak, U., Ma, J. Z., . . . Petri, W. A. J. (2019). Childhood growth and neurocognition are associated with distinct sets of metabolites. EBIOMEDICINE, 44, 597-606. doi:10.1016/j.ebiom.2019.05.043

Tan, S. -F., Dunton, W., Liu, X., Fox, T. E., Morad, S. A. F., Desai, D., . . . Loughran, T. P. (2019). Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-B-dependent P-glycoprotein upregulation. JOURNAL OF LIPID RESEARCH, 60(6), 1078-1086. doi:10.1194/jlr.M091876

Shah, A., Melhuish, T. A., Fox, T. E., Frierson, H. F. J., & Wotton, D. (2019). TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth. GENES & DEVELOPMENT, 33(7-8), 388-402. doi:10.1101/gad.320127.118

Kumar, M., Ji, B., Babaei, P., Das, P., Lappa, D., Ramakrishnan, G., . . . Nielsen, J. (2018). Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling. METABOLIC ENGINEERING, 49, 128-142. doi:10.1016/j.ymben.2018.07.018

Li, G., Liu, D., Kimchi, E. T., Kaifi, J. T., Qi, X., Manjunath, Y., . . . Staveley-O'Carroll, K. F. (2018). Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice. GASTROENTEROLOGY, 154(4), 1024-+. doi:10.1053/j.gastro.2017.10.050

Linton, S. S., Abraham, T., Liao, J., Clawson, G. A., Butler, P. J., Fox, T., . . . Matters, G. L. (2018). Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages. PLOS ONE, 13(11). doi:10.1371/journal.pone.0206759

Zhang, X., Kitatani, K., Toyoshima, M., Ishibashi, M., Usui, T., Minato, J., . . . Yaegashi, N. (2018). Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer. MOLECULAR CANCER THERAPEUTICS, 17(1), 50-59. doi:10.1158/1535-7163.MCT-17-0173

Shin, M., Snyder, H. W., Donyito, G., Schurman, L. D., Fox, T. E., Lichtman, A. H., . . . Hsu, K. -L. (2018). Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo. MOLECULAR PHARMACEUTICS, 15(3), 721-728. doi:10.1021/acs.molpharmaceut.7b00657

Loc, W. S., Linton, S. S., Wilczynski, Z. R., Matters, G. L., McGovern, C. O., Abraham, T., . . . Adair, J. H. (2017). Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 13(7), 2313-2324. doi:10.1016/j.nano.2017.06.017

Vijayan, M., Xia, C., Song, Y. E., Ngo, H., Studstill, C. J., Drews, K., . . . Hahm, B. (2017). Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. JOURNAL OF IMMUNOLOGY, 199(2), 677-687. doi:10.4049/jimmunol.1601959

Ganta, V. C., Choi, M. H., Kutateladze, A., Fox, T. E., Farber, C. R., & Annex, B. H. (2017). A MicroRNA93-Interferon Regulatory Factor-9-Immunoresponsive Gene-1-Itaconic Acid Pathway Modulates M2-Like Macrophage Polarization to Revascularize Ischemic Muscle. CIRCULATION, 135(24), 2403-+. doi:10.1161/CIRCULATIONAHA.116.025490

Hengst, J. A., Dick, T. E., Sharma, A., Doi, K., Hegde, S., Tan, S. -F., . . . Yun, J. K. (2017). SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.. Cancer translational medicine, 3(4), 109-121. doi:10.4103/ctm.ctm_7_17

Tan, S. -F., Liu, X., Fox, T. E., Barth, B. M., Sharma, A., Turner, S. D., . . . Loughran, T. P. J. (2016). Acid ceramidase is upregulated in AML and represents a novel therapeutic target. ONCOTARGET, 7(50), 83208-83222. doi:10.18632/oncotarget.13079

Young, M. M., Takahashi, Y., Fox, T. E., Yun, J. K., Kester, M., & Wang, H. -G. (2016). Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking. CELL REPORTS, 17(6), 1532-1545. doi:10.1016/j.celrep.2016.10.019

Morad, S. A. F., Ryan, T. E., Neufer, P. D., Zeczycki, T. N., Davis, T. S., MacDougall, M. R., . . . Cabot, M. C. (2016). Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. JOURNAL OF LIPID RESEARCH, 57(7), 1231-1242. doi:10.1194/jlr.M067389

Rivera, I. -G., Ordonez, M., Presa, N., Gangoiti, P., Gomez-Larrauri, A., Trueba, M., . . . Gomez-Munoz, A. (2016). Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells. BIOCHEMICAL PHARMACOLOGY, 102, 107-119. doi:10.1016/j.bcp.2015.12.009

Kester, M., Bassler, J., Fox, T. E., Carter, C. J., Davidson, J. A., & Parette, M. R. (2015). Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic. BIOLOGICAL CHEMISTRY, 396(6-7), 737-747. doi:10.1515/hsz-2015-0129

Morad, S. A. F., Tan, S. -F., Feith, D. J., Kester, M., Claxton, D. F., Loughran, T. P. J., . . . Cabot, M. C. (2015). Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia-Impact on enzyme activity and response to cytotoxics. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1851(7), 919-928. doi:10.1016/j.bbalip.2015.03.001

Haakenson, J. K., Khokhlatchev, A. V., Choi, Y. J., Linton, S. S., Zhang, P., Zaki, P. M., . . . Kester, M. (2015). Lysosomal Degradation of CD44 Mediates Ceramide Nanoliposome-induced Anoikis and Diminished Extravasation in Metastatic Carcinoma Cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 290(13), 8632-8643. doi:10.1074/jbc.M114.609677

Dick, T. E., Hengst, J. A., Fox, T. E., Colledge, A. L., Kale, V. P., Sung, S. -S., . . . Yun, J. K. (2015). The Apoptotic Mechanism of Action of the Sphingosine Kinase 1 Selective Inhibitor SKI-178 in Human Acute Myeloid Leukemia Cell Lines. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 352(3), 494-508. doi:10.1124/jpet.114.219659

LeBlanc, F. R., Liu, X., Hengst, J., Fox, T., Calvert, V., Petricoin, E. F. I. I. I., . . . Loughran, T. P. J. (2015). Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia. CANCER BIOLOGY & THERAPY, 16(12), 1830-1840. doi:10.1080/15384047.2015.1078949

Jones, K. A., Kim, P. D., Patel, B. B., Kelsen, S. G., Braverman, A., Swinton, D. J., . . . Yeung, A. T. (2013). Immunodepletion Plasma Proteomics by TripleTOF 5600 and Orbitrap Elite/LTQ-Orbitrap Velos/Q Exactive Mass Spectrometers. JOURNAL OF PROTEOME RESEARCH, 12(10), 4351-4365. doi:10.1021/pr400307u

Morad, S. A. F., Levin, J. C., Tan, S. -F., Fox, T. E., Feith, D. B., & Cabot, M. C. (2013). Novel off-target effect of tamoxifen - Inhibition of acid ceramidase activity in cancer cells. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1831(12), 1657-1664. doi:10.1016/j.bbalip.2013.07.016

Jiang, Y., DiVittore, N. A., Young, M. M., Jia, Z., Xie, K., Ritty, T. M., . . . Fox, T. E. (2013). Altered Sphingolipid Metabolism in Patients with Metastatic Pancreatic Cancer. BIOMOLECULES, 3(3), 435-448. doi:10.3390/biom3030435

Hankins, J. L., Ward, K. E., Linton, S. S., Barth, B. M., Stahelin, R. V., Fox, T. E., & Kester, M. (2013). Ceramide 1-Phosphate Mediates Endothelial Cell Invasion via the Annexin a2-p11 Heterotetrameric Protein Complex. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(27), 19726-19738. doi:10.1074/jbc.M113.481622

Barth, B. M., Shanmugavelandy, S. S., Kaiser, J. M., McGovern, C., Altnoglu, E. I., Haakenson, J. K., . . . Kester, M. (2013). PhotoImmunoNanoTherapy Reveals an Anticancer Role for Sphingosine Kinase 2 and Dihydrosphingosine-1-Phosphate. ACS NANO, 7(3), 2132-2144. doi:10.1021/nn304862b

Ryland, L. K., Doshi, U. A., Shanmugavelandy, S. S., Fox, T. E., Aliaga, C., Broeg, K., . . . Kester, M. (2013). C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia. PLOS ONE, 8(12). doi:10.1371/journal.pone.0084648

Watters, R. J., Fox, T. E., Tan, S. -F., Shanmugavelandy, S., Choby, J. E., Broeg, K., . . . Liu, X. (2013). Targeting glucosylceramide synthase synergizes with C₆-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia. LEUKEMIA & LYMPHOMA, 54(6), 1288-1296. doi:10.3109/10428194.2012.752485

Fox, T. E., Young, M. M., Pedersen, M. M., Han, X., Gardner, T. W., & Kester, M. (2012). Diabetes Diminishes Phosphatidic Acid in the Retina: A Putative Mediator for Reduced mTOR Signaling and Increased Neuronal Cell Death. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 53(11), 7257-7267. doi:10.1167/iovs.11-7626

Kaiser, J. M., Imai, H., Haakenson, J. K., Brucklacher, R. M., Fox, T. E., Shanmugavelandy, S. S., . . . Kester, M. (2013). Nanoliposomal minocycline for ocular drug delivery. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 9(1), 130-140. doi:10.1016/j.nano.2012.03.004

Madhunapantula, S. V., Hengst, J., Gowda, R., Fox, T. E., Yun, J. K., & Robertson, G. P. (2012). Targeting sphingosine kinase-1 to inhibit melanoma. PIGMENT CELL & MELANOMA RESEARCH, 25(2). doi:10.1111/j.1755-148X.2012.00970.x

Hankins, J. L., Fox, T. E., Barth, B. M., Unrath, K. A., & Kester, M. (2011). Exogenous Ceramide-1-phosphate Reduces Lipopolysaccharide (LPS)-mediated Cytokine Expression. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(52), 44357-44366. doi:10.1074/jbc.M111.264010

Jiang, Y., DiVittore, N. A., Kaiser, J. M., Shanmugavelandy, S. S., Fritz, J. L., Heakal, Y., . . . Kester, M. (2011). Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer. CANCER BIOLOGY & THERAPY, 12(7), 574-585. doi:10.4161/cbt.12.7.15971

Heakal, Y., Woll, M. P., Fox, T., Seaton, K., Levenson, R., & Kester, M. (2011). Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains. CANCER BIOLOGY & THERAPY, 12(5), 427-435. doi:10.4161/cbt.12.5.15984

Liao, A., Broeg, K., Fox, T., Tan, S. -F., Watters, R., Shah, M. V., . . . Liu, X. (2011). Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia. BLOOD, 118(10), 2793-2800. doi:10.1182/blood-2011-01-331447

O'Neill, S. M., Yun, J. K., Fox, T. E., & Kester, M. (2011). Transcriptional regulation of the human neutral ceramidase gene. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 511(1-2), 21-30. doi:10.1016/j.abb.2011.04.012

O'Neill, S. M., Houck, K. L., Yun, J. K., Fox, T. E., & Kester, M. (2011). AP-1 binding transcriptionally regulates human neutral ceramidase. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 511(1-2), 31-39. doi:10.1016/j.abb.2011.04.009

Ryland, L. K., Fox, T. E., Liu, X., Loughran, T. P., & Kester, M. (2011). Dysregulation of sphingolipid metabolism in cancer. CANCER BIOLOGY & THERAPY, 11(2), 138-149. doi:10.4161/cbt.11.2.14624

Fox, T. E., Young, M. M., Pedersen, M. M., Giambuzzi-Tussey, S., Kester, M., & Gardner, T. W. (2011). Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 300(3), E600-E609. doi:10.1152/ajpendo.00641.2010

Watters, R. J., Liu, X., Fox, T. E., Kester, M., & Loughran, T. P. (2011). Targeting the sphingolipid pathway in NK large granular lymphocyte leukemia. CANCER RESEARCH, 71. doi:10.1158/1538-7445.AM2011-4302

Takahashi, Y., Meyerkord, C. L., Hori, T., Runkle, K., Fox, T. E., Kester, M., . . . Wang, H. -G. (2011). Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. AUTOPHAGY, 7(1), 61-73. doi:10.4161/auto.7.1.14015

Barth, B. M., Gustafson, S. J., Young, M. M., Fox, T. E., Shanmugavelandy, S. S., Kaiser, J. M., . . . Kuhn, T. B. (2010). Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance. CANCER BIOLOGY & THERAPY, 10(11), 1126-1137. doi:10.4161/cbt.10.11.13438

Fox, T. E., Bewley, M. C., Unrath, K. A., Pedersen, M. M., Anderson, R. E., Jung, D. Y., . . . Kester, M. (2011). Circulating sphingolipid biomarkers in models of type 1 diabetes. JOURNAL OF LIPID RESEARCH, 52(3), 509-517. doi:10.1194/jlr.M010595

Winter, J. N., Fox, T. E., Kester, M., Jefferson, L. S., & Kimball, S. R. (2010). Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 299(2), C335-C344. doi:10.1152/ajpcell.00039.2010

Ganapathi, S. B., Fox, T. E., Kester, M., & Elmslie, K. S. (2010). Ceramide modulates HERG potassium channel gating by translocation into lipid rafts. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 299(1), C74-C86. doi:10.1152/ajpcell.00462.2009

Fox, T. E., & Kester, M. (2010). Therapeutic Strategies for Diabetes and Complications: A Role for Sphingolipids?. SPHINGOLIPIDS AS SIGNALING AND REGULATORY MOLECULES, 688, 206-216. Retrieved from https://www.webofscience.com/