Tajie H. Harris

Kovacs, M. A., Babcock, I. W., Marco, A. R., Sibley, L. A., Kelly, A. G., & Harris, T. H. (2024). Vascular Endothelial Growth Factor-C Treatment Enhances Cerebrospinal Fluid Outflow during Toxoplasma gondii Brain Infection but Does Not Improve Cerebral Edema. AMERICAN JOURNAL OF PATHOLOGY, 194(2), 225-237. doi:10.1016/j.ajpath.2023.11.008

Kovacs, M. A., Cowan, M. N., Babcock, I. W., Sibley, L. A., Still, K., Batista, S. J., . . . Harris, T. H. (2022). Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain. ELIFE, 11. doi:10.7554/eLife.80775

Cowan, M. N., Kovacs, M. A., Sethi, I., Babcock, I. W., Still, K., Batista, S. J., . . . Harris, T. H. (2022). Microglial STAT1-sufficiency is required for resistance to toxoplasmic encephalitis. PLOS PATHOGENS, 18(9). doi:10.1371/journal.ppat.1010637

Shallberg, L. A. H., Phan, A. T. A., Christian, D. A. A., Perry, J. A., Haskins, B. E., Beiting, D. P., . . . Hunter, C. A. (2022). Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8⁺ T cell response during acute and chronic toxoplasmosis. PLOS PATHOGENS, 18(6). doi:10.1371/journal.ppat.1010296

Cowan, M. N., Sethi, I., & Harris, T. H. (2022). Microglia in CNS infections: insights from Toxoplasma gondi and other pathogens. TRENDS IN PARASITOLOGY, 38(3), 217-229. doi:10.1016/j.pt.2021.12.004

Noffsinger, B., Witter, A., Sheybani, N., Xiao, A., Manigat, L., Zhong, Q., . . . Purow, B. (2021). Technical choices significantly alter the adaptive immune response against immunocompetent murine gliomas in a model-dependent manner. JOURNAL OF NEURO-ONCOLOGY, 154(2), 145-157. doi:10.1007/s11060-021-03822-7

Still, K. M., Batista, S. J., O'Brien, C. A., Oyesola, O. O., Fruh, S. P., Webb, L. M., . . . Harris, T. H. (2020). Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling. PLOS PATHOGENS, 16(10). doi:10.1371/journal.ppat.1009027

Batista, S. J., Still, K. M., Johanson, D., Thompson, J. A., O'Brien, C. A., Lukens, J. R., & Harris, T. H. (2020). Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-17491-z

Kovacs, M. A., & Harris, T. H. (2020). Long-'Trm' protection of the CNS. NATURE IMMUNOLOGY, 21(8), 825-826. doi:10.1038/s41590-020-0716-3

Batista, S., Still, K., Johanson, D., Thompson, J., O’Brien, C., Lukens, J., & Harris, T. (2020). Gasdermin-D-dependent IL-1αrelease from microglia promotes protective immunity during chronicToxoplasma gondiiinfection. doi:10.1101/2020.01.22.915652

O'Brien, C. A., & Harris, T. H. (2020). ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain. PLOS ONE, 15(1). doi:10.1371/journal.pone.0228251

Webb, L. M., Oyesola, O. O., Fruh, S. P., Kamynina, L., Still, K. M., Patel, R. K., . . . Wojno, E. D. T. (2019). The Notch signaling pathway promotes basophil responses during helminth-induced type 2 inflammation. JOURNAL OF EXPERIMENTAL MEDICINE, 216(6), 1268-1279. doi:10.1084/jem.20180131

O'Brien, C. A., Batista, S. J., Still, K. M., & Harris, T. H. (2019). IL-10 and ICOS Differentially Regulate T Cell Responses in the Brain during Chronic Toxoplasma gondii Infection. JOURNAL OF IMMUNOLOGY, 202(6), 1755-1766. doi:10.4049/jimmunol.1801229

Louveau, A., Herz, J., Alme, M. N., Salvador, A. F., Dong, M. Q., Viar, K. E., . . . Kipnis, J. (2018). CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. NATURE NEUROSCIENCE, 21(10), 1380-+. doi:10.1038/s41593-018-0227-9

Norris, G. T., Smirnov, I., Filiano, A. J., Shadowen, H. M., Cody, K. R., Thompson, J. A., . . . Kipnis, J. (2018). Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury. JOURNAL OF EXPERIMENTAL MEDICINE, 215(7), 1789-1801. doi:10.1084/jem.20172244

Still, K., Batista, S., O’Brien, C., Oyesola, O., Früh, S., Webb, L., . . . Harris, T. (2018). Astrocytes promote a protective immune response to brainToxoplasma gondiiinfection via IL-33-ST2 signaling. doi:10.1101/338400

Klein, R. S., Voskuhl, R., Segal, B. M., Dittel, B. N., Lane, T. E., Bethea, J. R., . . . Cross, A. H. (2017). Speaking out about gender imbalance in invited speakers improves diversity. NATURE IMMUNOLOGY, 18(5), 475-478. doi:10.1038/ni.3707

O'Brien, C. A., Overall, C., Konradt, C., Hall, A. C. O., Hayes, N. W., Wagage, S., . . . Harris, T. H. (2017). CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection. JOURNAL OF IMMUNOLOGY, 198(10), 4054-4061. doi:10.4049/jimmunol.1601581

Hidano, S., Randall, L. M., Dawson, L., Dietrich, H. K., Konradt, C., Klover, P. J., . . . Hunter, C. A. (2016). STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System. MBIO, 7(6). doi:10.1128/mBio.01881-16

Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., . . . Kipnis, J. (2016). Structural and functional features of central nervous system lymphatic vessels (vol 523, pg 337, 2015). NATURE, 533(7602). doi:10.1038/nature16999

Louyeau, A., Harris, T. H., & Kipnis, J. (2015). Revisiting the Mechanisms of CNS Immune Privilege. TRENDS IN IMMUNOLOGY, 36(10), 569-577. doi:10.1016/j.it.2015.08.006

Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., . . . Kipnis, J. (2015). Structural and functional features of central nervous system lymphatic vessels. NATURE, 523(7560), 337-+. doi:10.1038/nature14432

Landrith, T. A., Harris, T. H., & Wilson, E. H. (2015). Characteristics and critical function of CD8+T cells in the Toxoplasma-infected brain. SEMINARS IN IMMUNOPATHOLOGY, 37(3), 261-270. doi:10.1007/s00281-015-0487-3

Cronk, J. C., Derecki, N. C., Ji, E., Xu, Y., Lampano, A. E., Smirnov, I., . . . Kipnis, J. (2015). Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. IMMUNITY, 42(4), 679-691. doi:10.1016/j.immuni.2015.03.013

Banigan, E. J., Harris, T. H., Christian, D. A., Hunter, C. A., & Liu, A. J. (2015). Heterogeneous CD8⁺ T Cell Migration in the Lymph Node in the Absence of Inflammation Revealed by Quantitative Migration Analysis. PLOS COMPUTATIONAL BIOLOGY, 11(2). doi:10.1371/journal.pcbi.1004058

Rashighi, M., Agarwal, P., Richmond, J. M., Harris, T. H., Dresser, K., Su, M. -W., . . . Harris, J. E. (2014). CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo. SCIENCE TRANSLATIONAL MEDICINE, 6(223). doi:10.1126/scitranslmed.3007811

Settles, E. W., Moser, L. A., Harris, T. H., & Knoll, L. J. (2014). Toxoplasma gondii Upregulates Interleukin-12 To Prevent Plasmodium berghei-Induced Experimental Cerebral Malaria. INFECTION AND IMMUNITY, 82(3), 1343-1353. doi:10.1128/IAI.01259-13

Notarangelo, F. M., Wilson, E. H., Horning, K. J., Thomas, M. A. R., Harris, T. H., Fang, Q., . . . Schwarcz, R. (2014). Evaluation of kynurenine pathway metabolism in Toxoplasma gondii-infected mice: Implications for schizophrenia. SCHIZOPHRENIA RESEARCH, 152(1), 261-267. doi:10.1016/j.schres.2013.11.011

Butler, N. S., Harris, T. H., & Blader, I. J. (2013). Regulation of immunopathogenesis during Plasmodium and Toxoplasma infections: more parallels than distinctions?. TRENDS IN PARASITOLOGY, 29(12), 593-602. doi:10.1016/j.pt.2013.10.002

Hall, A. O., Beiting, D. P., Tato, C., John, B., Oldenhove, G., Lombana, C. G., . . . Hunter, C. A. (2012). The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology. IMMUNITY, 37(3), 511-523. doi:10.1016/j.immuni.2012.06.014

Harris, T. H., Banigan, E. J., Christian, D. A., Konradt, C., Wojno, E. D. T., Norose, K., . . . Hunter, C. A. (2012). Generalized Levy walks and the role of chemokines in migration of effector CD8⁺ T cells. NATURE, 486(7404), 545-U145. doi:10.1038/nature11098

Harris, J. E., Harris, T. H., Weninger, W., Wherry, E. J., Hunter, C. A., & Turka, L. A. (2012). A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8⁺ T-Cell Accumulation in the Skin. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 132(7), 1869-1876. doi:10.1038/jid.2011.463

Rashighi, M., Agarwal, P., Harris, T. H., Deng, A., Hunter, C. A., & Harris, J. E. (2012). CXCL10, an IFN-γ-induced chemokine, is required for the development of depigmentation in a mouse model of vitiligo. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 132, S1. Retrieved from https://www.webofscience.com/

Sansing, L. H., Harris, T. H., Welsh, F. A., Kasner, S. E., Hunter, C. A., & Kariko, K. (2011). Toll-like Receptor 4 Contributes to Poor Outcome after Intracerebral Hemorrhage. ANNALS OF NEUROLOGY, 70(4), 646-656. doi:10.1002/ana.22528

John, B., Ricart, B., Wojno, E. D. T., Harris, T. H., Randall, L. M., Christian, D. A., . . . Hunter, C. A. (2011). Analysis of Behavior and Trafficking of Dendritic Cells within the Brain during Toxoplasmic Encephalitis. PLOS PATHOGENS, 7(9). doi:10.1371/journal.ppat.1002246

Sansing, L. H., Harris, T. H., Kasner, S. E., Hunter, C. A., & Kariko, K. (2011). Neutrophil Depletion Diminishes Monocyte Infiltration and Improves Functional Outcome After Experimental Intracerebral Hemorrhage. INTRACEREBRAL HEMORRHAGE RESEARCH: FROM BENCH TO BEDSIDE, 111, 173-178. doi:10.1007/978-3-7091-0693-8_29

Norose, K., Kikumura, A., Luster, A. D., Hunter, C. A., & Harris, T. H. (2011). CXCL10 Is Required to Maintain T-Cell Populations and to Control Parasite Replication during Chronic Ocular Toxoplasmosis. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 52(1), 389-398. doi:10.1167/iovs.10-5819

Harris, J. E., Harris, T. H., Weninger, W., Wherry, E. J., Hunter, C. A., & Turka, L. A. (2011). A new mouse model of vitiligo with epidermal depigmentation reveals a critical role for IFN-gamma in autoreactive T cell homing to the skin. PIGMENT CELL & MELANOMA RESEARCH, 24(4), 808. Retrieved from https://www.webofscience.com/

Tait, E. D., Jordan, K. A., Dupont, C. D., Harris, T. H., Gregg, B., Wilson, E. H., . . . Hunter, C. A. (2010). Virulence of Toxoplasma gondii Is Associated with Distinct Dendritic Cell Responses and Reduced Numbers of Activated CD8⁺ T Cells. JOURNAL OF IMMUNOLOGY, 185(3), 1502-1512. doi:10.4049/jimmunol.0903450

Harris, T. H., Wilson, E. H., Tait, E. D., Buckley, M., Shapira, S., Caamano, J., . . . Hunter, C. A. (2010). NF-κB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS. JOURNAL OF NEUROIMMUNOLOGY, 222(1-2), 19-28. doi:10.1016/j.jneuroim.2009.12.009