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Todd Bauer

Todd Bauer

Stephen H. Watts Professor of Surgery; Chief, Division of Surgical Oncology, Surgery

Bio & Overview

The Bauer laboratory is focused on developing novel therapies for the treatment of pancreatic cancer and colorectal cancer.

Academic Information

Department
Surgery
Academic Title
Associate Professor

Primary Education

  • BA, Biology, University of Pennsylvania, Philadelphia, PA, 1991
  • BS, Economics, University of Pennsylvania, Philadelphia, PA, 1991
  • MD, Surgery, University of Pennsylvania, Philadelphia, PA, 1995

Other Affiliations

  • Member, Cancer Cell Signaling Program

Research Interests

Cancer metastasis, chemotherapy resistance, genetic and epigenetic regulation

Research Disciplines

  • Cancer Biology
  • Experimental Pathology

Research Opportunities

  • Cancer Biology
  • Experimental Pathology

PhD Programs

  • Experimental Pathology

Selected Publications

2024

Perez, I. C., Bigelow, A., Shami, V. M., Sauer, B. G., Wang, A. Y., Strand, D. S., . . . Buerlein, R. C. D. (2024). Comparative accuracy of four guidelines to predict high-grade dysplasia or malignancy in surgically resected pancreatic intraductal papillary mucinous neoplasms: Small nuances between guidelines lead to vastly different results.. Annals of hepato-biliary-pancreatic surgery. doi:10.14701/ahbps.24-049

Brown, B. A., Myers, P. J., Adair, S. J., Pitarresi, J. R., Sah-Teli, S. K., Campbell, L. A., . . . Lazzara, M. J. (2024). A Histone Methylation-MAPK Signaling Axis Drives Durable Epithelial-Mesenchymal Transition in Hypoxic Pancreatic Cancer. CANCER RESEARCH, 84(11), 1764-1780. doi:10.1158/0008-5472.CAN-22-2945

Rane, A., Jarmoshti, J., Abdullah-Bin, S., Adair, S., Torres-Castro, K., Honrado, C., . . . Swami, N. S. (2024). Dielectrophoretic enrichment of live chemo-resistant circulating-like pancreatic cancer cells from media of drug-treated adherent cultures of solid tumors. LAB ON A CHIP, 24(3), 561-571. doi:10.1039/d3lc00804e

2023

Alaimo, L., Moazzam, Z., Lima, H. A., Endo, Y., Ruzzenente, A., Guglielmi, A., . . . Pawlik, T. M. (2023). An attempt to establish and apply global benchmarks for liver resection of malignant hepatic tumors. SURGERY, 174(6), 1384-1392. doi:10.1016/j.surg.2023.08.024

Ali, L. R., Lenehan, P. J., Cardot-Ruffino, V., Dias Costa, A., Katz, M. H. G., Bauer, T. W., . . . Dougan, S. K. (2024). PD-1 Blockade Induces Reactivation of Nonproductive T-Cell Responses Characterized by NF-κB Signaling in Patients with Pancreatic Cancer. CLINICAL CANCER RESEARCH, 30(3), 542-553. doi:10.1158/1078-0432.CCR-23-1444

Lattimore, C. M. M., Kane, W. J. J., Subbarao, S., Venitti, C., Cramer, C. L. L., Turkheimer, L. M. M., . . . Zaydfudim, V. M. M. (2023). Long-term surveillance of branch-duct intraductal papillary mucinous neoplasms without worrisome or high-risk features. JOURNAL OF SURGICAL ONCOLOGY, 128(7), 1087-1094. doi:10.1002/jso.27414

Alaimo, L., Lima, H. A., Moazzam, Z., Endo, Y., Yang, J., Ruzzenente, A., . . . Pawlik, T. M. (2023). ASO Visual Abstract: Development and Validation of a Machine Learning Model to Predict Early Recurrence of Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(9), 5418-5419. doi:10.1245/s10434-023-13712-z

Alaimo, L., Lima, H. A., Moazzam, Z., Endo, Y., Yang, J., Ruzzenente, A., . . . Pawlik, T. M. M. (2023). Development and Validation of a Machine-Learning Model to Predict Early Recurrence of Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(9), 5406-5415. doi:10.1245/s10434-023-13636-8

Alaimo, L., Moazzam, Z., Endo, Y., Lima, H. A., Butey, S. P., Ruzzenente, A., . . . Pawlik, T. M. (2023). ASO Visual Abstract: The Application of Artificial Intelligence to Investigate Long-Term Outcomes and Assess Optimal Margin Width in Hepatectomy for Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(7), 4304-4305. doi:10.1245/s10434-023-13411-9

Endo, Y., Moazzam, Z., Woldesenbet, S., Lima, H. A., Alaimo, L., Munir, M. M., . . . Pawlik, T. M. (2023). Predictors and Prognostic Significance of Postoperative Complications for Patients with Intrahepatic Cholangiocarcinoma. WORLD JOURNAL OF SURGERY, 47(7), 1792-1800. doi:10.1007/s00268-023-06974-x

Salahi, A., Honrado, C., Moore, J., Adair, S., Bauer, T. W., & Swami, N. S. (2023). Supervised learning on impedance cytometry data for label-free biophysical distinction of pancreatic cancer cells versus their associated fibroblasts under gemcitabine treatment. BIOSENSORS & BIOELECTRONICS, 231. doi:10.1016/j.bios.2023.115262

Alaimo, L., Moazzam, Z., Endo, Y., Lima, H. A., Butey, S. P., Ruzzenente, A., . . . Pawlik, T. M. (2023). The Application of Artificial Intelligence to Investigate Long-Term Outcomes and Assess Optimal Margin Width in Hepatectomy for Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(7), 4292-4301. doi:10.1245/s10434-023-13349-y

Endo, Y., Moazzam, Z., Lima, H. A., Alaimo, L., Munir, M. M., Shaikh, C. F., . . . Pawlik, T. M. (2023). The impact of tumor location on the value of lymphadenectomy for intrahepatic cholangiocarcinoma. HPB, 25(6), 650-658. doi:10.1016/j.hpb.2023.02.013

Munir, M. M., Endo, Y., Lima, H. A., Alaimo, L., Moazzam, Z., Shaikh, C., . . . Pawlik, T. M. (2023). Albumin-Bilirubin Grade and Tumor Burden Score Predict Outcomes Among Patients with Intrahepatic Cholangiocarcinoma After Hepatic Resection: a Multi-Institutional Analysis. JOURNAL OF GASTROINTESTINAL SURGERY, 27(3), 544-554. doi:10.1007/s11605-023-05578-z

Moazzam, Z., Alaimo, L., Endo, Y., Lima, H. A., Ruzzenente, A., Guglielmi, A., . . . Pawlik, T. M. (2023). Combined Tumor Burden Score and Carbohydrate Antigen 19-9 Grading System to Predict Outcomes Among Patients with Intrahepatic Cholangiocarcinoma. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 236(4), 804-813. doi:10.1097/XCS.0000000000000557

Gamache, A., Conarroe, C., Adair, S., Bauer, T., Padilla, F., & Bullock, T. N. J. (2023). Interrogating the CD27:CD70 axis in αCD40-dependent control of pancreatic adenocarcinoma. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 11. doi:10.3389/fcell.2023.1173686

2022

Alaimo, L., Moazzam, Z., Endo, Y., Lima, H. A., Ruzzenente, A., Guglielmi, A., . . . Pawlik, T. M. (2023). ASO Visual Abstract: Long-Term Recurrence-Free and Overall Survival Differ Based on Common, Proliferative, and Inflammatory Subtypes After Resection of Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(3), 1406-1407. doi:10.1245/s10434-022-12856-8

Zhang, X. -F., Xue, F., Weiss, M., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2023). Lymph Node Examination and Patterns of Nodal Metastasis Among Patients with Left- Versus Right-Sided Intrahepatic Cholangiocarcinoma After Major Curative-Intent Resection. ANNALS OF SURGICAL ONCOLOGY, 30(3), 1424-1433. doi:10.1245/s10434-022-12797-2

Endo, Y., Sasaki, K., Moazzam, Z., Lima, H. A., Alaimo, L., Guglielmi, A., . . . Pawlik, T. M. (2023). Higher Tumor Burden Status Dictates the Impact of Surgical Margin Status on Overall Survival in Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(4), 2023-2032. doi:10.1245/s10434-022-12803-7

Alaimo, L., Moazzam, Z., Endo, Y., Lima, H. A., Ruzzenente, A., Guglielmi, A., . . . Pawlik, T. M. (2023). Long-Term Recurrence-Free and Overall Survival Differ Based on Common, Proliferative, and Inflammatory Subtypes After Resection of Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 30(3), 1392-1403. doi:10.1245/s10434-022-12795-4

Endo, Y., Moazzam, Z., Alaimo, L., Lima, H. A., Munir, M. M., Shaikh, C. F., . . . Pawlik, T. M. (2023). Predictive risk-score model to select patients with intrahepatic cholangiocarcinoma for adjuvant chemotherapy. HPB, 25(2), 229-238. doi:10.1016/j.hpb.2022.10.011

Honrado, C., Salahi, A., Adair, S. J., Moore, J. H., Bauer, T. W., & Swami, N. S. (2022). Automated biophysical classification of apoptotic pancreatic cancer cell subpopulations by using machine learning approaches with impedance cytometry. LAB ON A CHIP, 22(19), 3708-3720. doi:10.1039/d2lc00304j

Alaimo, L., Moazzam, Z., Brown, Z. J., Endo, Y., Ruzzenente, A., Guglielmi, A., . . . Pawlik, T. M. (2023). ASO Visual Abstract: Application of Hazard Function to Investigate Recurrence of Intrahepatic Cholangiocarcinoma After Curative-Intent Liver Resection: A Novel Approach to Characterize Recurrence. ANNALS OF SURGICAL ONCOLOGY, 30(3), 1352-1353. doi:10.1245/s10434-022-12575-0

Alaimo, L., Moazzam, Z., Brown, Z. J., Endo, Y., Ruzzenente, A., Guglielmi, A., . . . Pawlik, T. M. (2023). Application of Hazard Function to Investigate Recurrence of Intrahepatic Cholangiocarcinoma After Curative-Intent Liver Resection: A Novel Approach to Characterize Recurrence. ANNALS OF SURGICAL ONCOLOGY, 30(3), 1340-1349. doi:10.1245/s10434-022-12463-7

Spolverato, G., Capelli, G., Lorenzoni, G., Gregori, D., He, J., Popescu, I., . . . Pawlik, T. M. (2022). ASO Visual Abstract: Dynamic Prediction of Survival After Curative Resection of Intrahepatic Cholangiocarcinoma: A Landmarking-Based Analysis. ANNALS OF SURGICAL ONCOLOGY, 29(12), 7644-7645. doi:10.1245/s10434-022-12290-w

Spolverato, G., Capelli, G., Lorenzoni, G., Gregori, D., He, J., Popescu, I., . . . Pawlik, T. M. (2022). Dynamic Prediction of Survival After Curative Resection of Intrahepatic Cholangiocarcinoma: A Landmarking-Based Analysis. ANNALS OF SURGICAL ONCOLOGY, 29(12), 7634-7641. doi:10.1245/s10434-022-12156-1

Franssen, S., Soares, K. C., Jolissaint, J. S., Tsilimigras, D. I., Buettner, S., Alexandrescu, S., . . . Koerkamp, B. G. (2022). Comparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma. JAMA SURGERY, 157(7), 590-596. doi:10.1001/jamasurg.2022.1298

Lattimore, C. M., Kane, W. J., Sarosiek, B. M., Coleman, C. M., Turrentine, F. E., Forkin, K. T., . . . Zaydfudim, V. M. (2022). Efficacy of opioid spinal analgesia for postoperative pain management after pancreatoduodenectomy. HPB, 24(11), 1930-1936. doi:10.1016/j.hpb.2022.06.002

Wei, T., Zhang, X. -F., He, J., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2022). Prognostic impact of perineural invasion in intrahepatic cholangiocarcinoma: multicentre study. BRITISH JOURNAL OF SURGERY, 109(7), 610-616. doi:10.1093/bjs/znac098

Ozturk, H., Cingoz, H., Tufan, T., Yang, J., Adair, S. J., Tummala, K. S., . . . Adli, M. (2022). ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer. DEVELOPMENTAL CELL, 57(11), 1331-+. doi:10.1016/j.devcel.2022.04.014

Tsilimigras, D. I., Ejaz, A., Cloyd, J., Guglielmi, A., Aldrighetti, L., Weiss, M., . . . Pawlik, T. M. (2022). Tumor Necrosis Impacts Prognosis of Patients Undergoing Resection for T1 Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 29(7), 4326-4334. doi:10.1245/s10434-022-11462-y

Tsilimigras, D. I., Ejaz, A., Cloyd, J., Guglielmi, A., Aldrighetti, L., Weiss, M., . . . Pawlik, T. M. (2022). ASO Visual Abstract: Tumor Necrosis Impacts the Prognosis of Patients Undergoing Resection for T1 Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 29(7), 4335-4336. doi:10.1245/s10434-022-11485-5

Nishioka, Y., Chun, Y. S., Overman, M. J., Cao, H. S. T., Tzeng, C. -W. D., Mason, M. C., . . . Newhook, T. E. (2022). Effect of Co-mutation of RAS and TP53 on Postoperative ctDNA Detection and Early Recurrence after Hepatectomy for Colorectal Liver Metastases. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 234(4), 474-483. doi:10.1097/XCS.0000000000000093

Buerlein, R. C. D., Strand, D. S., Uppal, D. S., Patrie, J. T., Sauer, B. G., Shami, V. M., . . . Wang, A. Y. (2022). Endobiliary Ablation Improves Survival in Patients With Unresectable Perihilar Cholangiocarcinoma Compared to Stenting Alone. TECHNIQUES AND INNOVATIONS IN GASTROINTESTINAL ENDOSCOPY, 24(3), 226-233. doi:10.1016/j.tige.2022.01.002

2021

Kunk, P. R., Dougherty, S. C., Lynch, K., Whitehair, R., Meneveau, M., Obeid, J. M., . . . Rahma, O. E. (2021). Myeloid Cell Infiltration Correlates With Prognosis in Cholangiocarcinoma and Varies Based on Tumor Location. JOURNAL OF IMMUNOTHERAPY, 44(7), 254-263. doi:10.1097/CJI.0000000000000378

Honrado, C., Adair, S. J., Moore, J. H., Salahi, A., Bauer, T. W., & Swami, N. S. (2021). Apoptotic Bodies in the Pancreatic Tumor Cell Culture Media Enable Label-Free Drug Sensitivity Assessment by Impedance Cytometry. ADVANCED BIOLOGY, 5(8). doi:10.1002/adbi.202100438

Dong, G., Boukhechba, M., Shaffer, K. M., Ritterband, L. M., Gioeli, D. G., Reilley, M. J., . . . Chow, P. I. (2021). Using Graph Representation Learning to Predict Salivary Cortisol Levels in Pancreatic Cancer Patients. JOURNAL OF HEALTHCARE INFORMATICS RESEARCH, 5(4), 401-419. doi:10.1007/s41666-021-00098-4

Zhang, X. -F., Xue, F., He, J., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2021). Proposed modification of the eighth edition of the AJCC staging system for intrahepatic cholangiocarcinoma. HPB, 23(9), 1456-1466. doi:10.1016/j.hpb.2021.02.009

2020

Tsilimigras, D. I., Hyer, J. M., Paredes, A. Z., Moris, D., Sahara, K., Guglielmi, A., . . . Pawlik, T. M. (2021). Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy?. ANNALS OF SURGICAL ONCOLOGY, 28(4), 1970-1978. doi:10.1245/s10434-020-09393-7

Wei, X., Yang, J., Adair, S. J., Ozturk, H., Kuscu, C., Lee, K. Y., . . . Adli, M. (2020). Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(45), 28068-28079. doi:10.1073/pnas.2009899117

Thiele, R. H., Sarosiek, B. M., Modesitt, S. C., McMurry, T. L., Tiouririne, M., Martin, L. W., . . . Hedrick, T. L. (2021). Development and Impact of an Institutional Enhanced Recovery Program on Opioid Use, Length of Stay, and Hospital Costs Within an Academic Medical Center: A Cohort Analysis of 7774 Patients. ANESTHESIA AND ANALGESIA, 132(2), 442-455. doi:10.1213/ANE.0000000000005182

Tsilimigras, D. I., Sahara, K., Wu, L., Moris, D., Bagante, F., Guglielmi, A., . . . Pawlik, T. M. (2020). Very Early Recurrence After Liver Resection for Intrahepatic Cholangiocarcinoma Considering Alternative Treatment Approaches. JAMA SURGERY, 155(9), 823-831. doi:10.1001/jamasurg.2020.1973

Tsilimigras, D. I., Sahara, K., Paredes, A. Z., Moro, A., Mehta, R., Moris, D., . . . Pawlik, T. M. (2021). Predicting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma. JOURNAL OF GASTROINTESTINAL SURGERY, 25(5), 1156-1163. doi:10.1007/s11605-020-04720-5

Tsilimigras, D. I., Hyer, J. M., Paredes, A. Z., Diaz, A., Moris, D., Guglielmi, A., . . . Pawlik, T. M. (2020). A Novel Classification of Intrahepatic Cholangiocarcinoma Phenotypes Using Machine Learning Techniques: An International Multi-Institutional Analysis. ANNALS OF SURGICAL ONCOLOGY, 27(13), 5224-5232. doi:10.1245/s10434-020-08696-z

Xiang, J. -X., Zhang, X. -F., Weiss, M., Aldrighetti, L., Poultsides, G. A., Bauer, T. W., . . . Pawlik, T. M. (2020). Multi-institutional Development and External Validation of a Nomogram Predicting Recurrence After Curative Liver Resection for Neuroendocrine Liver Metastasis. ANNALS OF SURGICAL ONCOLOGY, 27(10), 3717-3726. doi:10.1245/s10434-020-08620-5

Tsilimigras, D. I., Sahara, K., Moris, D., Mehta, R., Paredes, A. Z., Ratti, F., . . . Pawlik, T. M. (2020). Assessing Textbook Outcomes Following Liver Surgery for Primary Liver Cancer Over a 12-Year Time Period at Major Hepatobiliary Centers. ANNALS OF SURGICAL ONCOLOGY, 27(9), 3318-3327. doi:10.1245/s10434-020-08548-w

Tsilimigras, D. I., Moris, D., Mehta, R., Paredes, A. Z., Sahara, K., Guglielmi, A., . . . Pawlik, T. M. (2020). The systemic immune-inflammation index predicts prognosis in intrahepatic cholangiocarcinoma: an international multi-institutional analysis. HPB, 22(12), 1667-1674. doi:10.1016/j.hpb.2020.03.011

Moro, A., Mehta, R., Sahara, K., Tsilimigras, D. I., Paredes, A. Z., Farooq, A., . . . Pawlik, T. M. (2020). The Impact of Preoperative CA19-9 and CEA on Outcomes of Patients with Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 27(8), 2888-2901. doi:10.1245/s10434-020-08350-8

Zaydfudim, V. M., Turrentine, F. E., Smolkin, M. E., Bauer, T. B., Adams, R. B., & McMurry, T. L. (2020). The impact of cirrhosis and MELD score on postoperative morbidity and mortality among patients selected for liver resection. AMERICAN JOURNAL OF SURGERY, 220(3), 682-686. doi:10.1016/j.amjsurg.2020.01.022

Zhang, X. -F., Xue, F., Dong, D. -H., Weiss, M., Popescu, I., Marques, H. P., . . . Pawlik, T. M. (2021). Number and Station of Lymph Node Metastasis After Curative-intent Resection of Intrahepatic Cholangiocarcinoma Impact Prognosis. ANNALS OF SURGERY, 274(6), E1187-E1195. doi:10.1097/SLA.0000000000003788

2019

McGrath, J. S., Honrado, C., Moore, J. H., Adair, S. J., Varhue, W. B., Salahi, A., . . . Swami, N. S. (2020). Electrophysiology-based stratification of pancreatic tumorigenicity by label-free single-cell impedance cytometry. ANALYTICA CHIMICA ACTA, 1101, 90-98. doi:10.1016/j.aca.2019.12.033

Hu, L. -S., Zhang, X. -F., Weiss, M., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2020). Redefining Conditional Overall and Disease-Free Survival After Curative Resection for Intrahepatic Cholangiocarcinoma: a Multi-institutional, International Study of 1221 patients. JOURNAL OF GASTROINTESTINAL SURGERY, 24(12), 2756-2765. doi:10.1007/s11605-019-04472-x

Tsilimigras, D. I., Mehta, R., Moris, D., Sahara, K., Bagante, F., Paredes, A. Z., . . . Pawlik, T. M. (2020). A Machine-Based Approach to Preoperatively Identify Patients with the Most and Least Benefit Associated with Resection for Intrahepatic Cholangiocarcinoma: An International Multi-institutional Analysis of 1146 Patients. ANNALS OF SURGICAL ONCOLOGY, 27(4), 1110-1119. doi:10.1245/s10434-019-08067-3

Spolverato, G., Bagante, F., Aldrighetti, L., Poultsides, G., Bauer, T. W., Fields, R. C., . . . Pawlik, T. M. (2020). Neuroendocrine Liver Metastasis: Prognostic Implications of Primary Tumor Site on Patients Undergoing Curative Intent Liver Surgery (vol 21, pg 2039, 2017). JOURNAL OF GASTROINTESTINAL SURGERY, 24(1), 231. doi:10.1007/s11605-019-04371-1

Moro, A., Paredes, A. Z., Farooq, A., Sahara, K., Tsilimigras, D. I., Mehta, R., . . . Soubrane, O. (2019). Discordance in prediction of prognosis among patients with intrahepatic cholangiocarcinoma: A preoperative vs postoperative perspective. JOURNAL OF SURGICAL ONCOLOGY, 120(6), 946-955. doi:10.1002/jso.25671

Nagdas, S., Kashatus, J. A., Nascimento, A., Hussain, S. S., Trainor, R. E., Pollock, S. R., . . . Kashatus, D. F. (2019). Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth. CELL REPORTS, 28(7), 1845-+. doi:10.1016/j.celrep.2019.07.031

Bagante, F., Spolverato, G., Merath, K., Weiss, M., Alexandrescu, S., Marques, H. P., . . . Pawlik, T. M. (2019). Intrahepatic cholangiocarcinoma tumor burden: A classification and regression tree model to define prognostic groups after resection. SURGERY, 166(6), 983-990. doi:10.1016/j.surg.2019.06.005

Merath, K., Chen, Q., Bagante, F., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2019). A Multi-institutional International Analysis of Textbook Outcomes Among Patients Undergoing Curative-Intent Resection of Intrahepatic Cholangiocarcinoma. JAMA SURGERY, 154(6). doi:10.1001/jamasurg.2019.0571

Sahara, K., Tsilimigras, D. I., Merath, K., Bagante, F., Guglielmi, A., Aldrighetti, L., . . . Pawlik, T. M. (2019). Therapeutic Index Associated with Lymphadenectomy Among Patients with Intrahepatic Cholangiocarcinoma: Which Patients Benefit the Most from Nodal Evaluation?. ANNALS OF SURGICAL ONCOLOGY, 26(9), 2959-2968. doi:10.1245/s10434-019-07483-9

Tsilimigras, D. I., Hyer, J. M., Moris, D., Sahara, K., Bagante, F., Guglielmi, A., . . . Soubrane, O. (2019). Prognostic utility of albumin-bilirubin grade for short- and long-term outcomes following hepatic resection for intrahepatic cholangiocarcinoma: A multi-institutional analysis of 706 patients. JOURNAL OF SURGICAL ONCOLOGY, 120(2), 206-213. doi:10.1002/jso.25486

Hu, L. -S., Zhang, X. -F., Weiss, M., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2019). Recurrence Patterns and Timing Courses Following Curative-Intent Resection for Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 26(8), 2549-2557. doi:10.1245/s10434-019-07353-4

Zhang, X. -F., Lv, Y., Weiss, M., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2019). Should Utilization of Lymphadenectomy Vary According to Morphologic Subtype of Intrahepatic Cholangiocarcinoma?. ANNALS OF SURGICAL ONCOLOGY, 26(7), 2242-2250. doi:10.1245/s10434-019-07336-5

Buettner, S., ten Cate, D. W. G., Bagante, F., Alexandrescu, S., Marques, H. P., Lamelas, J., . . . Koerkamp, B. G. (2019). Survival after Resection of Multiple Tumor Foci of Intrahepatic Cholangiocarcinoma. JOURNAL OF GASTROINTESTINAL SURGERY, 23(11), 2239-2246. doi:10.1007/s11605-019-04184-2

Merath, K., Mehta, R., Hyer, J. M., Bagante, F., Sahara, K., Alexandrescu, S., . . . Pawlik, T. M. (2019). Impact of body mass index on tumor recurrence among patients undergoing curative-intent resection of intrahepatic cholangiocarcinoma- a multi-institutional international analysis. EJSO, 45(6), 1084-1091. doi:10.1016/j.ejso.2019.03.004

Martin, A. N., Wilkins, L. R., Das, D., Johnston, L. E., Bauer, T. W., Adams, R. B., & Zaydfudim, V. M. (2019). Efficacy of Radiofrequency Ablation versus Transarterial Chemoembolization for Patients with Solitary Hepatocellular Carcinoma ≤3 cm. AMERICAN SURGEON, 85(2), 150-155. Retrieved from https://www.webofscience.com/

Gioeli, D., Snow, C. J., Simmers, M. B., Hoang, S. A., Figler, R. A., Allende, J. A., . . . Wamhoff, B. R. (2019). Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells. LAB ON A CHIP, 19(7), 1193-1204. doi:10.1039/c8lc00755a

2018

Hu, L. -S., Weiss, M., Popescu, I., Marques, H. P., Aldrighetti, L., Maithel, S. K., . . . Pawlik, T. M. (2019). Impact of microvascular invasion on clinical outcomes after curative-intent resection for intrahepatic cholangiocarcinoma. JOURNAL OF SURGICAL ONCOLOGY, 119(1), 21-29. doi:10.1002/jso.25305

Szlachta, K., Kuscu, C., Tufan, T., Adair, S. J., Shang, S., Michaels, A. D., . . . Adli, M. (2018). CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response. NATURE COMMUNICATIONS, 9. doi:10.1038/s41467-018-06676-2

Xiang, J. -X., Zhang, X. -F., Weiss, M., Aldrighetti, L., Poultsides, G. A., Bauer, T. W., . . . Pawlik, T. M. (2018). Early recurrence of well-differentiated (G1) neuroendocrine liver metastasis after curative-intent surgery: Risk factors and outcome. JOURNAL OF SURGICAL ONCOLOGY, 118(7), 1096-1104. doi:10.1002/jso.25246

Xiang, J. -X., Zhang, X. -F., Beal, E. W., Weiss, M., Aldrighetti, L., Poultsides, G. A., . . . Pawlik, T. M. (2018). Hepatic Resection for Non-functional Neuroendocrine Liver Metastasis: Does the Presence of Unresected Primary Tumor or Extrahepatic Metastatic Disease Matter?. ANNALS OF SURGICAL ONCOLOGY, 25(13), 3928-3935. doi:10.1245/s10434-018-6751-8

Sham, J. G., Ejaz, A., Gage, M. M., Bagante, F., Reames, B. N., Maithel, S., . . . He, J. (2019). The Impact of Extent of Liver Resection Among Patients with Neuroendocrine Liver Metastasis: an International Multi-institutional Study. JOURNAL OF GASTROINTESTINAL SURGERY, 23(3), 484-491. doi:10.1007/s11605-018-3862-2

Narayanan, S., Martin, A. N., Turrentine, F. E., Bauer, T. W., Adams, R. B., & Zaydfudim, V. M. (2018). Mortality after pancreaticoduodenectomy: assessing early and late causes of patient death. JOURNAL OF SURGICAL RESEARCH, 231, 304-308. doi:10.1016/j.jss.2018.05.075

Bagante, F., Weiss, M., Alexandrescu, S., Marques, H. P., Aldrighetti, L., Maithel, S. K., . . . Pawlik, T. M. (2018). Long-term outcomes of patients with intraductal growth sub-type of intrahepatic cholangiocarcinoma. HPB, 20(12), 1189-1197. doi:10.1016/j.hpb.2018.05.017

Buettner, S., Spolverato, G., Kimbrough, C. W., Alexandrescu, S., Marques, H. P., Lamelas, J., . . . Pawlik, T. M. (2018). The impact of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio among patients with intrahepatic cholangiocarcinoma. SURGERY, 164(3), 411-418. doi:10.1016/j.surg.2018.05.002

Sasaki, K., Margonis, G. A., Andreatos, N., Chen, Q., Barbon, C., Bagante, F., . . . Pawlik, T. M. (2018). Serum tumor markers enhance the predictive power of the AJCC and LCSGJ staging systems in resectable intrahepatic cholangiocarcinoma. HPB, 20(10), 956-965. doi:10.1016/j.hpb.2018.04.005

Zhang, X. -F., Chakedis, J., Bagante, F., Chen, Q., Beal, E. W., Lv, Y., . . . Pawlik, T. M. (2018). Trends in use of lymphadenectomy in surgery with curative intent for intrahepatic cholangiocarcinoma. BRITISH JOURNAL OF SURGERY, 105(7), 857-866. doi:10.1002/bjs.10827

Zhang, X. -F., Bagante, F., Chen, Q., Beal, E. W., Lv, Y., Weiss, M., . . . Pawlik, T. M. (2018). Perioperative and long-term outcome of intrahepatic cholangiocarcinoma involving the hepatic hilus after curative-intent resection: comparison with peripheral intrahepatic cholangiocarcinoma and hilar cholangiocarcinoma. SURGERY, 163(5), 1114-1120. doi:10.1016/j.surg.2018.01.001

Bagante, F., Merath, K., Squires, M. H., Weiss, M., Alexandrescu, S., Marques, H. P., . . . Pawlik, T. M. (2018). The Limitations of Standard Clinicopathologic Features to Accurately Risk-Stratify Prognosis after Resection of Intrahepatic Cholangiocarcinoma. JOURNAL OF GASTROINTESTINAL SURGERY, 22(3), 477-485. doi:10.1007/s11605-018-3682-4

Knapp, K. A., Pires, E. S., Adair, S. J., Mandal, A., Mills, A. M., Olson, W. C., . . . Herr, J. C. (2018). Evaluation of SAS1B as a target for antibody-drug conjugate therapy in the treatment of pancreatic cancer.. Oncotarget, 9(10), 8972-8984. doi:10.18632/oncotarget.23944

Bagante, F., Spolverato, G., Weiss, M., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2018). Surgical Management of Intrahepatic Cholangiocarcinoma in Patients with Cirrhosis: Impact of Lymphadenectomy on Peri-Operative Outcomes. WORLD JOURNAL OF SURGERY, 42(8), 2551-2560. doi:10.1007/s00268-017-4453-1

Martin, A. N., Narayanan, S., Turrentine, F. E., Bauer, T. W., Adams, R. B., & Zaydfudim, V. M. (2018). Pancreatic duct size and gland texture are associated with pancreatic fistula after pancreaticoduodenectomy but not after distal pancreatectomy. PLOS ONE, 13(9). doi:10.1371/journal.pone.0203841

Hu, Y., Johnston, L. E., Shami, V. M., Bauer, T. W., Adams, R. B., Stukenborg, G. J., & Zaydfudim, V. M. (2018). Comparative Effectiveness of Resection vs Surveillance for Pancreatic Branch Duct Intraductal Papillary Mucinous Neoplasms With Worrisome Features. JAMA SURGERY, 153(3), 225-232. doi:10.1001/jamasurg.2017.4587

Arner, D. M., Corning, B. E., Ahmed, A. M., Ho, H. C., Weinbaum, B. J., Siddiqui, U., . . . Sauer, B. G. (2018). Molecular analysis of pancreatic cyst fluid changes clinical management. ENDOSCOPIC ULTRASOUND, 7(1), 29-33. doi:10.4103/eus.eus_22_17

2017

Michaels, A. D., Newhook, T. E., Adair, S. J., Morioka, S., Gaudreau, B. J., Nagdas, S., . . . Bauer, T. W. (2018). CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer. CLINICAL CANCER RESEARCH, 24(6), 1415-1425. doi:10.1158/1078-0432.CCR-17-2283

Sasaki, K., Margonis, G. A., Andreatos, N., Bagante, F., Weiss, M., Barbon, C., . . . Pawlik, T. M. (2018). Preoperative Risk Score and Prediction of Long-Term Outcomes after Hepatectomy for Intrahepatic Cholangiocarcinoma. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 226(4), 393-405. doi:10.1016/j.jamcollsurg.2017.12.011

Martin, A. N., Narayanan, S., Turrentine, F. E., Bauer, T. W., Adams, R. B., Stukenborg, G. J., & Zaydfudim, V. M. (2018). Clinical Factors and Postoperative Impact of Bile Leak After Liver Resection. JOURNAL OF GASTROINTESTINAL SURGERY, 22(4), 661-667. doi:10.1007/s11605-017-3650-4

Zhang, X. -F., Beal, E. W., Bagante, F., Chakedis, J., Weiss, M., Popescu, I., . . . Pawlik, T. M. (2018). Early versus late recurrence of intrahepatic cholangiocarcinoma after resection with curative intent. BRITISH JOURNAL OF SURGERY, 105(7), 848-856. doi:10.1002/bjs.10676

Ejaz, A., Reames, B. N., Maithel, S., Poultsides, G. A., Bauer, T. W., Fields, R. C., . . . Pawlik, T. M. (2018). Cytoreductive debulking surgery among patients with neuroendocrine liver metastasis: a multi-institutional analysis. HPB, 20(3), 277-284. doi:10.1016/j.hpb.2017.08.039

Zhang, X. -F., Beal, E. W., Weiss, M., Aldrighetti, L., Poultsides, G. A., Bauer, T. W., . . . Pawlik, T. M. (2018). Timing of disease occurrence and hepatic resection on long-term outcome of patients with neuroendocrine liver metastasis. JOURNAL OF SURGICAL ONCOLOGY, 117(2), 171-181. doi:10.1002/jso.24832

Zhang, X. -F., Chakedis, J., Bagante, F., Beal, E. W., Lv, Y., Weiss, M., . . . Pawlik, T. M. (2018). Implications of Intrahepatic Cholangiocarcinoma Etiology on Recurrence and Prognosis after Curative-Intent Resection: a Multi-Institutional Study. WORLD JOURNAL OF SURGERY, 42(3), 849-857. doi:10.1007/s00268-017-4199-9

Bagante, F., Spolverato, G., Weiss, M., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2017). Defining Long-Term Survivors Following Resection of Intrahepatic Cholangiocarcinoma. JOURNAL OF GASTROINTESTINAL SURGERY, 21(11), 1888-1897. doi:10.1007/s11605-017-3550-7

Spolverato, G., Bagante, F., Aldrighetti, L., Poultsides, G., Bauer, T. W., Field, R. C., . . . Pawlik, T. M. (2017). Neuroendocrine Liver Metastasis: Prognostic Implications of Primary Tumor Site on Patients Undergoing Curative Intent Liver Surgery. JOURNAL OF GASTROINTESTINAL SURGERY, 21(12), 2039-2047. doi:10.1007/s11605-017-3491-1

Zhang, X. -F., Bagante, F., Chakedis, J., Moris, D., Beal, E. W., Weiss, M., . . . Pawlik, T. M. (2017). Perioperative and Long-Term Outcome for Intrahepatic Cholangiocarcinoma: Impact of Major Versus Minor Hepatectomy. JOURNAL OF GASTROINTESTINAL SURGERY, 21(11), 1841-1850. doi:10.1007/s11605-017-3499-6

Zhang, X. -F., Beal, E. W., Chakedis, J., Lv, Y., Bagante, F., Aldrighetti, L., . . . Pawlik, T. M. (2017). Early Recurrence of Neuroendocrine Liver Metastasis After Curative Hepatectomy: Risk Factors, Prognosis, and Treatment. JOURNAL OF GASTROINTESTINAL SURGERY, 21(11), 1821-1830. doi:10.1007/s11605-017-3490-2

Reames, B. N., Bagante, F., Ejaz, A., Spolverato, G., Ruzzenente, A., Weiss, M., . . . Pawlik, T. M. (2017). Impact of adjuvant chemotherapy on survival in patients with intrahepatic cholangiocarcinoma: a multi-institutional analysis. HPB, 19(10), 901-909. doi:10.1016/j.hpb.2017.06.008

Buettner, S., Galjart, B., van Vugt, J. L. A., Bagante, F., Alexandrescu, S., Marques, H. P., . . . Pawlik, T. M. (2017). Performance of prognostic scores and staging systems in predicting long-term survival outcomes after surgery for intrahepatic cholangiocarcinoma. JOURNAL OF SURGICAL ONCOLOGY, 116(8), 1085-1095. doi:10.1002/jso.24759

Ejaz, A., Reames, B. N., Maithel, S., Poultsides, G. A., Bauer, T. W., Fields, R. C., . . . Pawlik, T. M. (2017). The impact of extrahepatic disease among patients undergoing liver-directed therapy for neuroendocrine liver metastasis. JOURNAL OF SURGICAL ONCOLOGY, 116(7), 841-847. doi:10.1002/jso.24727

Spolverato, G., Bagante, F., Aldrighetti, L., Poultsides, G. A., Bauer, T. W., Fields, R. C., . . . Pawlik, T. M. (2017). Management and outcomes of patients with recurrent neuroendocrine liver metastasis after curative surgery: An international multi-institutional analysis. JOURNAL OF SURGICAL ONCOLOGY, 116(3), 298-306. doi:10.1002/jso.24670

Bagante, F., Spolverato, G., Weiss, M., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2017). Impact of Morphological Status on Long-Term Outcome Among Patients Undergoing Liver Surgery for Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 24(9), 2491-2501. doi:10.1245/s10434-017-5870-y

Bagante, F., Spolverato, G., Weiss, M., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2018). Assessment of the Lymph Node Status in Patients Undergoing Liver Resection for Intrahepatic Cholangiocarcinoma: the New Eighth Edition AJCC Staging System. JOURNAL OF GASTROINTESTINAL SURGERY, 22(1), 52-59. doi:10.1007/s11605-017-3426-x

Reames, B. N., Ejaz, A., Koerkamp, B. G., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2017). Impact of major vascular resection on outcomes and survival in patients with intrahepatic cholangiocarcinoma: A multi-institutional analysis. JOURNAL OF SURGICAL ONCOLOGY, 116(2), 133-139. doi:10.1002/jso.24633

Spolverato, G., Bagante, F., Weiss, M., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2017). Comparative performances of the 7th and the 8th editions of the American Joint Committee on Cancer staging systems for intrahepatic cholangiocarcinoma. JOURNAL OF SURGICAL ONCOLOGY, 115(6), 696-703. doi:10.1002/jso.24569

Bagante, F., Spolverato, G., Merath, K., Postlewait, L. M., Poultsides, G. A., Mullen, M. G., . . . Pawlik, T. M. (2017). Neuroendocrine liver metastasis: The chance to be cured after liver surgery. JOURNAL OF SURGICAL ONCOLOGY, 115(6), 687-695. doi:10.1002/jso.24563

Buettner, S., Koerkamp, B. G., Ejaz, A., Buisman, F. E., Kim, Y., Margonis, G. A., . . . Pawlik, T. M. (2017). The effect of preoperative chemotherapy treatment in surgically treated intrahepatic cholangiocarcinoma patients-A multi-institutional analysis. JOURNAL OF SURGICAL ONCOLOGY, 115(3), 312-318. doi:10.1002/jso.24524

2016

Martin, A. N., Kerwin, M. J., Turrentine, F. E., Bauer, T. W., Adams, R. B., Stukenborg, G. J., & Zaydfudim, V. M. (2016). Blood transfusion is an independent predictor of morbidity and mortality after hepatectomy. JOURNAL OF SURGICAL RESEARCH, 206(1), 106-112. doi:10.1016/j.jss.2016.07.013

Martin, A. N., Das, D., Turrentine, F. E., Bauer, T. W., Adams, R. B., & Zaydfudim, V. M. (2016). Morbidity and Mortality After Gastrectomy: Identification of Modifiable Risk Factors. JOURNAL OF GASTROINTESTINAL SURGERY, 20(9), 1554-1564. doi:10.1007/s11605-016-3195-y

Margonis, G. A., Buettner, S., Sasaki, K., Kim, Y., Ratti, F., Russolillo, N., . . . Pawlik, T. M. (2016). The role of liver-directed surgery in patients with hepatic metastasis from primary breast cancer: a multi-institutional analysis. HPB, 18(8), 700-705. doi:10.1016/j.hpb.2016.05.014

Bagante, F., Spolverato, G., Cucchetti, A., Gani, F., Popescu, I., Ruzzenente, A., . . . Pawlik, T. M. (2016). Defining when to offer operative treatment for intrahepatic cholangiocarcinoma: A regret-based decision curves analysis. SURGERY, 160(1), 106-117. doi:10.1016/j.surg.2016.01.023

Margonis, G. A., Samaha, M., Kim, Y., Postlewait, L. M., Kunz, P., Maithel, S., . . . Pawlik, T. M. (2016). A Multi-institutional Analysis of Duodenal Neuroendocrine Tumors: Tumor Biology Rather than Extent of Resection Dictates Prognosis. JOURNAL OF GASTROINTESTINAL SURGERY, 20(6), 1098-1105. doi:10.1007/s11605-016-3135-x

Newhook, T. E., Lindberg, J. M., Adair, S. J., Kim, A. J., Stelow, E. B., Rahma, O. E., . . . Bauer, T. W. (2016). Adjuvant Trametinib Delays the Outgrowth of Occult Pancreatic Cancer in a Mouse Model of Patient-Derived Liver Metastasis. ANNALS OF SURGICAL ONCOLOGY, 23(6), 1993-2000. doi:10.1245/s10434-016-5116-4

Vitale, A., Spolverato, G., Bagante, F., Gani, F., Popescu, I., Marques, H. P., . . . Pawlik, T. M. (2016). A multi-institutional analysis of elderly patients undergoing a liver resection for intrahepatic cholangiocarcinoma. JOURNAL OF SURGICAL ONCOLOGY, 113(4), 420-426. doi:10.1002/jso.24148

Kunk, P. R., Bauer, T. W., Slingluff, C. L., & Rahma, O. E. (2016). From bench to bedside a comprehensive review of pancreatic cancer immunotherapy. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 4. doi:10.1186/s40425-016-0119-z

Michaels, A., Lindberg, J. M., Newhook, T., Adair, S. J., Mullen, M. G., Parsons, J., & Bauer, T. W. (2016). Probing Compensatory Signaling to MEK Inhibition Uncovers the Vulnerability of Pancreatic Cancer to Dual Therapy with Trametinib Plus Foretinib. ANNALS OF SURGICAL ONCOLOGY, 23, S6-S7. Retrieved from https://www.webofscience.com/

2015

Zaydfudim, V. M., Kerwin, M. J., Turrentine, F. E., Bauer, T. W., Adams, R. B., & Stukenborg, G. J. (2016). The impact of chronic liver disease on the risk assessment of ACS NSQIP morbidity and mortality after hepatic resection. SURGERY, 159(5), 1308-1315. doi:10.1016/j.surg.2015.11.020

Newhook, T. E., Lapar, D. J., Walters, D. M., Gupta, S., Jolissaint, J. S., Adams, R. B., . . . Bauer, T. W. (2015). Impact of Postoperative Venous Thromboembolism on Postoperative Morbidity, Mortality, and Resource Utilization after Hepatectomy. AMERICAN SURGEON, 81(12), 1216-1223. Retrieved from https://www.webofscience.com/

Walters, D. M., Shada, A. L., LaPar, D. J., Adams, R. B., & Bauer, T. W. (2015). A Long Gastrojejunostomy Is Associated With Decreased Incidence and Severity of Delayed Gastric Emptying After Pancreaticoduodenectomy. PANCREAS, 44(8), 1273-1279. doi:10.1097/MPA.0000000000000415

Bagante, F., Gani, F., Spolverato, G., Xu, L., Alexandrescu, S., Marques, H. P., . . . Pawlik, T. M. (2015). Intrahepatic Cholangiocarcinoma: Prognosis of Patients Who Did Not Undergo Lymphadenectomy. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 221(6), 1031-+. doi:10.1016/j.jamcollsurg.2015.09.012

Zaydfudim, V. M., McMurry, T. L., Harrigan, A. M., Friel, C. M., Stukenborg, G. J., Bauer, T. W., . . . Hedrick, T. L. (2015). Improving treatment and survival: a population-based study of current outcomes after a hepatic resection in patients with metastatic colorectal cancer. HPB, 17(11), 1019-1024. doi:10.1111/hpb.12488

Spolverato, G., Vitale, A., Cucchetti, A., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2015). Can hepatic resection provide a long-term cure for patients with intrahepatic cholangiocarcinoma?. CANCER, 121(22), 3998-4006. doi:10.1002/cncr.29619

Newhook, T. E., LaPar, D. J., Lindberg, J. M., Bauer, T. W., Adams, R. B., & Zaydfudim, V. M. (2016). Morbidity and mortality of hepatectomy for benign liver tumors. AMERICAN JOURNAL OF SURGERY, 211(1), 102-108. doi:10.1016/j.amjsurg.2015.06.010

Zaydfudim, V. M., Wang, A. Y., de Lange, E. E., Zhao, Z., Moskaluk, C. A., Bauer, T. W., & Adams, R. B. (2015). IgG4-Associated Cholangitis Can Mimic Hilar Cholangiocarcinoma. GUT AND LIVER, 9(4), 556-560. doi:10.5009/gnl14241

Spolverato, G., Kim, Y., Alexandrescu, S., Marques, H. P., Lamelas, J., Aldrighetti, L., . . . Pawlik, T. M. (2016). Management and Outcomes of Patients with Recurrent Intrahepatic Cholangiocarcinoma Following Previous Curative-Intent Surgical Resection. ANNALS OF SURGICAL ONCOLOGY, 23(1), 235-243. doi:10.1245/s10434-015-4642-9

Soares, K. C., Kim, Y., Spolverato, G., Maithel, S., Bauer, T. W., Marques, H., . . . Pawlik, T. M. (2015). Presentation and Clinical Outcomes of Choledochal Cysts in Children and Adults A Multi-institutional Analysis. JAMA SURGERY, 150(6), 577-584. doi:10.1001/jamasurg.2015.0226

Spolverato, G., Kim, Y., Ejaz, A., Alexandrescu, S., Marques, H., Aldrighetti, L., . . . Pawlik, T. M. (2015). Conditional Probability of Long-term Survival After Liver Resection for Intrahepatic Cholangiocarcinoma A Multi-institutional Analysis of 535 Patients. JAMA SURGERY, 150(6), 538-545. doi:10.1001/jamasurg.2015.0219

Spolverato, G., Maqsood, H., Vitale, A., Alexandrescu, S., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2015). Readmission After Liver Resection for Intrahepatic Cholangiocarcinoma: a Multi-Institutional Analysis. JOURNAL OF GASTROINTESTINAL SURGERY, 19(7), 1334-1341. doi:10.1007/s11605-015-2826-z

Spolverato, G., Yakoob, M. Y., Kim, Y., Alexandrescu, S., Marques, H. P., Lamelas, J., . . . Pawlik, T. M. (2015). Impact of Complications on Long-Term Survival After Resection of Intrahepatic Cholangiocarcinoma. CANCER, 121(16), 2730-2739. doi:10.1002/cncr.29419

Bischof, D. A., Kim, Y., Dodson, R., Jimenez, M. C., Behman, R., Cocieru, A., . . . Pawlik, T. M. (2015). Conditional Disease-Free Survival After Surgical Resection of Gastrointestinal Stromal Tumors A Multi-institutional Analysis of 502 Patients. JAMA SURGERY, 150(4), 299-306. doi:10.1001/jamasurg.2014.2881

Newhook, T. E., LaPar, D. J., Lindberg, J. M., Bauer, T. W., Adams, R. B., & Zaydfudim, V. M. (2015). Morbidity and Mortality of Pancreaticoduodenectomy for Benign and Premalignant Pancreatic Neoplasms. JOURNAL OF GASTROINTESTINAL SURGERY, 19(6), 1072-1077. doi:10.1007/s11605-015-2799-y

Spolverato, G., Yakoob, M. Y., Kim, Y., Alexandrescu, S., Marques, H. P., Lamelas, J., . . . Pawlik, T. M. (2015). The Impact of Surgical Margin Status on Long-Term Outcome After Resection for Intrahepatic Cholangiocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 22(12), 4020-4028. doi:10.1245/s10434-015-4472-9

Bischof, D. A., Dodson, R., Jimenez, M. C., Behman, R., Cocieru, A., Blazer, D. G. I. I. I., . . . Pawlik, T. M. (2015). Adherence to Guidelines for Adjuvant Imatinib Therapy for GIST: A Multi-institutional Analysis. JOURNAL OF GASTROINTESTINAL SURGERY, 19(6), 1022-1028. doi:10.1007/s11605-015-2782-7

Arnaoutakis, D. J., Kim, Y., Pulitano, C., Zaydfudim, V., Squires, M. H., Kooby, D., . . . Pawlik, T. M. (2015). Management of Biliary Cystic Tumors: A Multi-institutional Analysis of a Rare Liver Tumor. ANNALS OF SURGERY, 261(2), 361-367. doi:10.1097/SLA.0000000000000543

2014

Margonis, G. A., Spolverato, G., Kim, Y., Marques, H., Poultsides, G., Maithel, S., . . . Pawlik, T. M. (2015). Minimally Invasive Resection of Choledochal Cyst: a Feasible and Safe Surgical Option. JOURNAL OF GASTROINTESTINAL SURGERY, 19(5), 858-865. doi:10.1007/s11605-014-2722-y

Spolverato, G., Kim, Y., Alexandrescu, S., Popescu, I., Marques, H. P., Aldrighetti, L., . . . Pawlik, T. M. (2015). Is Hepatic Resection for Large or Multifocal Intrahepatic Cholangiocarcinoma Justified? Results from a Multi-Institutional Collaboration. ANNALS OF SURGICAL ONCOLOGY, 22(7), 2218-2225. doi:10.1245/s10434-014-4223-3

Bischof, D. A., Kim, Y., Behman, R., Karanicolas, P. J., Quereshy, F. A., Blazer, D. G. I. I. I., . . . Pawlik, T. M. (2014). A Nomogram to Predict Disease-Free Survival After Surgical Resection of GIST. JOURNAL OF GASTROINTESTINAL SURGERY, 18(12), 2123-2129. doi:10.1007/s11605-014-2658-2

Lindberg, J. M., Newhook, T. E., Adair, S. J., Walters, D. M., Kim, A. J., Stelow, E. B., . . . Bauer, T. W. (2014). Co-Treatment with Panitumumab and Trastuzumab Augments Response to the MEK Inhibitor Trametinib in a Patient-Derived Xenograft Model of Pancreatic Cancer. NEOPLASIA, 16(7), 562-571. doi:10.1016/j.neo.2014.06.004

Zhu, A. X., Borger, D. R., Kim, Y., Cosgrove, D., Ejaz, A., Alexandrescu, S., . . . Pawlik, T. M. (2014). Genomic Profiling of Intrahepatic Cholangiocarcinoma: Refining Prognosis and Identifying Therapeutic Targets. ANNALS OF SURGICAL ONCOLOGY, 21(12), 3827-3834. doi:10.1245/s10434-014-3828-x

Bischof, D. A., Kim, Y., Blazer, D. G. I. I. I., Behman, R., Karanicolas, P. J., Law, C. H., . . . Pawlik, T. M. (2014). Surgical Management of Advanced Gastrointestinal Stromal Tumors: An International Multi-Institutional Analysis of 158 Patients. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 219(3), 439-449. doi:10.1016/j.jamcollsurg.2014.02.037

Spolverato, G., Ejaz, A., Kim, Y., Sotiropoulos, G. C., Pau, A., Alexandrescu, S., . . . Pawlik, T. M. (2014). Tumor Size Predicts Vascular Invasion and Histologic Grade Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma. JOURNAL OF GASTROINTESTINAL SURGERY, 18(7), 1284-1291. doi:10.1007/s11605-014-2533-1

Strand, D. S., Cosgrove, N. D., Patrie, J. T., Cox, D. G., Bauer, T. W., Adams, R. B., . . . Wang, A. Y. (2014). ERCP-directed radiofrequency ablation and photodynamic therapy are associated with comparable survival in the treatment of unresectable cholangiocarcinoma. GASTROINTESTINAL ENDOSCOPY, 80(5), 794-804. doi:10.1016/j.gie.2014.02.1030

Hyder, O., Marques, H., Pulitano, C., Marsh, J. W., Alexandrescu, S., Bauer, T. W., . . . Pawlik, T. M. (2014). A Nomogram to Predict Long-term Survival After Resection for Intrahepatic Cholangiocarcinoma An Eastern and Western Experience. JAMA SURGERY, 149(5), 432-438. doi:10.1001/jamasurg.2013.5168

Bischof, D. A., Kim, Y., Dodson, R., Jimenez, M. C., Behman, R., Cocieru, A., . . . Pawlik, T. M. (2014). Open Versus Minimally Invasive Resection of Gastric GIST: A Multi-Institutional Analysis of Short- and Long-Term Outcomes. ANNALS OF SURGICAL ONCOLOGY, 21(9), 2941-2948. doi:10.1245/s10434-014-3733-3

Newhook, T. E., Blais, E. M., Lindberg, J. M., Adair, S. J., Xin, W., Lee, J. K., . . . Bauer, T. W. (2014). A Thirteen-Gene Expression Signature Predicts Survival of Patients with Pancreatic Cancer and Identifies New Genes of Interest. PLOS ONE, 9(9). doi:10.1371/journal.pone.0105631

Chakraborty, S., Morris, M. M., Bauer, T. W., Adams, R. B., Stelow, E. B., Petroni, G., & Sanoff, H. K. (2014). Accelerated fraction radiotherapy with capecitabine as neoadjuvant therapy for borderline resectable pancreatic cancer.. Gastrointestinal cancer research : GCR, 7(1), 15-22.

2013

Soares, K. C., Arnaoutakis, D. J., Kamel, I., Anders, R., Adams, R. B., Bauer, T. W., & Pawlik, T. M. (2014). Cystic Neoplasms of the Liver: Biliary Cystadenoma and Cystadenocarcinoma. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 218(1), 119-128. doi:10.1016/j.jamcollsurg.2013.08.014

Hyder, O., Hatzaras, I., Sotiropoulos, G. C., Paul, A., Alexandrescu, S., Marques, H., . . . Pawlik, T. M. (2013). Recurrence after operative management of intrahepatic cholangiocarcinoma. SURGERY, 153(6), 811-818. doi:10.1016/j.surg.2012.12.005

Abdalla, E. K., Bauer, T. W., Chun, Y. S., D'Angelica, M., Kooby, D. A., & Jarnagin, W. R. (2013). Locoregional surgical and interventional therapies for advanced colorectal cancer liver metastases: expert consensus statements. HPB, 15(2), 119-130. doi:10.1111/j.1477-2574.2012.00597.x

Walters, D. M., Lindberg, J. M., Adair, S. J., Newhook, T. E., Cowan, C. R., Stokes, J. B., . . . Bauer, T. W. (2013). Inhibition of the Growth of Patient-Derived Pancreatic Cancer Xenografts with the MEK Inhibitor Trametinib Is Augmented by Combined Treatment with the Epidermal Growth Factor Receptor/HER2 Inhibitor Lapatinib. NEOPLASIA, 15(2), 143-U207. doi:10.1593/neo.121712

Walters, D. M., Stokes, J. B., Adair, S. J., Stelow, E. B., Borgman, C. A., Lowrey, B. T., . . . Bauer, T. W. (2013). Clinical, Molecular and Genetic Validation of a Murine Orthotopic Xenograft Model of Pancreatic Adenocarcinoma Using Fresh Human Specimens. PLOS ONE, 8(10). doi:10.1371/journal.pone.0077065

2012

Walters, D. M., McGarey, P., LaPar, D. J., Strong, A., Good, E., Adams, R. B., & Bauer, T. W. (2013). A 6-day clinical pathway after a pancreaticoduodenectomy is feasible, safe and efficient. HPB, 15(9), 668-673. doi:10.1111/hpb.12016

de Jong, M. C., Marques, H., Clary, B. M., Bauer, T. W., Marsh, J. W., Ribero, D., . . . Pawlik, T. M. (2012). The impact of portal vein resection on outcomes for hilar cholangiocarcinoma. CANCER, 118(19), 4737-4747. doi:10.1002/cncr.27492

Chakraborty, S., Bauer, T. W., Morris, M. M., Yarde, E., Parsons, J. T., Adams, R. B., & Sanoff, H. K. (2012). Accelerated fraction radiotherapy with concomitant capecitabine as neoadjuvant therapy of borderline resectable pancreatic cancer.. J Clin Oncol, 30(4_suppl), 329. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/27983147

2011

Stokes, J. B., Adair, S. J., Slack-Davis, J. K., Walters, D. M., Tilghman, R. W., Hershey, E. D., . . . Bauer, T. W. (2011). Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment. MOLECULAR CANCER THERAPEUTICS, 10(11), 2135-2145. doi:10.1158/1535-7163.MCT-11-0261

de Jong, M. C., Nathan, H., Sotiropoulos, G. C., Paul, A., Alexandrescu, S., Marques, H., . . . Pawlik, T. M. (2011). Intrahepatic Cholangiocarcinoma: An International Multi-Institutional Analysis of Prognostic Factors and Lymph Node Assessment. JOURNAL OF CLINICAL ONCOLOGY, 29(23), 3140-3145. doi:10.1200/JCO.2011.35.6519

Mayo, S. C., de Jong, M. C., Bloomston, M., Pulitano, C., Clary, B. M., Reddy, S. K., . . . Pawlik, T. M. (2011). Surgery Versus Intra-arterial Therapy for Neuroendocrine Liver Metastasis: A Multicenter International Analysis. ANNALS OF SURGICAL ONCOLOGY, 18(13), 3657-3665. doi:10.1245/s10434-011-1832-y

Walters, D. M., Stokes, J. B., Adams, R. B., & Bauer, T. W. (2011). Use of a Falciform Ligament Pedicle Flap to Decrease Pancreatic Fistula After Distal Pancreatectomy. PANCREAS, 40(4), 595-599. doi:10.1097/MPA.0b013e3182153a4e

Walters, D. M., LaPar, D. J., de Lange, E. E., Sarti, M., Stokes, J. B., Adams, R. B., & Bauer, T. W. (2011). Pancreas-Protocol Imaging at a High-Volume Center Leads to Improved Preoperative Staging of Pancreatic Ductal Adenocarcinoma. ANNALS OF SURGICAL ONCOLOGY, 18(10), 2764-2771. doi:10.1245/s10434-011-1693-4

Pawlik, T. M., Pulitano, C., Alexandrescu, S., Gamblin, T. C., Ferrone, C., Sotiropoulos, G., . . . International Intrahepatic Cholangiocarcinoma Collaborative Group. (2011). Intrahepatic cholangiocarcinoma: An international, multi-institutional analysis of prognostic factors and lymph node assessment.. J Clin Oncol, 29(4_suppl), 162. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/27985653

Stokes, J. B., Nolan, N. J., Stelow, E. B., Walters, D. M., Weiss, G. R., de Lange, E. E., . . . Bauer, T. W. (2011). Preoperative Capecitabine and Concurrent Radiation for Borderline Resectable Pancreatic Cancer. ANNALS OF SURGICAL ONCOLOGY, 18(3), 619-627. doi:10.1245/s10434-010-1456-7

2010

Bausch, D., Thomas, S., Mino-Kenudson, M., Fernandez-del Castillo, C., Bauer, T. W., Williams, M., . . . Kelly, K. A. (2011). Plectin-1 as a Novel Biomarker for Pancreatic Cancer. CLINICAL CANCER RESEARCH, 17(2), 302-309. doi:10.1158/1078-0432.CCR-10-0999

Pop, G. H., Richter, J. A., Sauer, B., Rehan, M. E., Ho, H. C., Adams, R. B., . . . Kahaleh, M. (2011). Bridge to surgery using partially covered self-expandable metal stents (PCMS) in malignant biliary stricture: an acceptable paradigm?. SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 25(2), 613-618. doi:10.1007/s00464-010-1231-7

Mayo, S. C., de Jong, M. C., Pulitano, C., Clary, B. M., Reddy, S. K., Gamblin, T. C., . . . Pawlik, T. M. (2010). Surgical Management of Hepatic Neuroendocrine Tumor Metastasis: Results from an International Multi-Institutional Analysis. ANNALS OF SURGICAL ONCOLOGY, 17(12), 3129-3136. doi:10.1245/s10434-010-1154-5

Bonatti, H. J. R., Harris, T., Bauer, T., Enfield, K., Sabri, S., Sawyer, R. G., . . . Hagspiel, K. D. (2010). Transfemoral Catheter Thrombolysis and Use of Sildenafil in Acute Massive Pulmonary Embolism. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 24(6), 980-984. doi:10.1053/j.jvca.2009.12.009