Volker Kiessling

Nyenhuis S. B., Karandikar N., Kiessling V., Kreutzberger A. J. B., Thapa A., Liang B., Tamm L. K., Cafiso D. S., Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact, 2021; Nat Commun. 12(1) 761. PMID: | PMCID: PMC7859215

Lee J., Kreutzberger A. J. B., Odongo L., Nelson E. A., Nyenhuis D. A., Kiessling V., Liang B., Cafiso D. S., White J. M., Tamm L. K., Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry, 2021; Nat Struct Mol Biol. 28(2) 181-189. PMID: | PMCID: PMC7992113

Narahari A. K., Kreutzberger A. J., Gaete P. S., Chiu Y. H., Leonhardt S. A., Medina C. B., Jin X., Oleniacz P. W., Kiessling V., Barrett P. Q., Ravichandran K. S., Yeager M., Contreras J. E., Tamm L. K., Bayliss D. A., ATP and large signaling metabolites flux through caspase-activated Pannexin 1 channels, 2021; Elife. 10() . PMID: | PMCID: PMC7806264

Kreutzberger A. J. B., Kiessling V., Doyle C. A., Schenk N., Upchurch C. M., Elmer-Dixon M., Ward A. E., Preobraschenski J., Hussein S. S., Tomaka W., Seelheim P., Kattan I., Harris M., Liang B., Kenworthy A. K., Desai B. N., Leitinger N., Anantharam A., Castle J. D., Tamm L. K., Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2, 2020; Elife. 9() . PMID: | PMCID: PMC7738183

Ward A. E., Kiessling V., Pornillos O., White J. M., Ganser-Pornillos B. K., Tamm L. K., HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy, 2020; J Biol Chem. 295(45) 15183-15195. PMID: | PMCID: PMC7650252

Kreutzberger A. J. B., Kiessling V., Stroupe C., Liang B., Preobraschenski J., Ganzella M., Kreutzberger M. A. B., Nakamoto R., Jahn R., Castle J. D., Tamm L. K., In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties, 2019; Nat Commun. 10(1) 3904. PMID: | PMCID: PMC6715626

Kiessling V., Kreutzberger A. J. B., Liang B., Nyenhuis S. B., Seelheim P., Castle J. D., Cafiso D. S., Tamm L. K., A molecular mechanism for calcium-mediated synaptotagmin-triggered exocytosis, 2018; Nat Struct Mol Biol. 25(10) 911-917. PMID: | PMCID: PMC6176490

Blackburn MR, Hubbard C, Kiessling V, Bi Y, Kloss B, Tamm LK, Zimmer J, Distinct reaction mechanisms for hyaluronan biosynthesis in different kingdoms of life., 2017; Glycobiology. 28(2) 108-121. PMID: 29190396

Kreutzberger AJB, Kiessling V, Liang B, Yang ST, Castle JD, Tamm LK, Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability., 2017; Biophysical journal. 113(9) 1912-1915. PMID: 29037600 | PMCID: PMC5685784

Kreutzberger AJB, Kiessling V, Liang B, Seelheim P, Jakhanwal S, Jahn R, Castle JD, Tamm LK, Reconstitution of calcium-mediated exocytosis of dense-core vesicles., 2017; Science advances. 3(7) e1603208. PMID: 28776026 | PMCID: PMC5517108

Yang ST, Kreutzberger AJB, Kiessling V, Ganser-Pornillos BK, White JM, Tamm LK, HIV virions sense plasma membrane heterogeneity for cell entry., 2017; Science advances. 3(6) e1700338. PMID: 28782011 | PMCID: PMC5489272

Kiessling V, Liang B, Kreutzberger AJ, Tamm LK, Planar Supported Membranes with Mobile SNARE Proteins and Quantitative Fluorescence Microscopy Assays to Study Synaptic Vesicle Fusion., 2017; Frontiers in molecular neuroscience. 10() 72. PMID: 28360838 | PMCID: PMC5352703

Zdanowicz R, Kreutzberger A, Liang B, Kiessling V, Tamm LK, Cafiso DS, Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion., 2017; Biophysical journal. 113(6) 1235-1250. PMID: 28456331 | PMCID: PMC5607037

Chiu YH, Jin X, Medina CB, Leonhardt SA, Kiessling V, Bennett BC, Shu S, Tamm LK, Yeager M, Ravichandran KS, Bayliss DA, A quantized mechanism for activation of pannexin channels., 2017; Nature communications. 8() 14324. PMID: 28134257 | PMCID: PMC5290276

Kiessling V., Liang B., Kreutzberger A. J., Tamm L. K., Planar Supported Membranes with Mobile SNARE Proteins and Quantitative Fluorescence Microscopy Assays to Study Synaptic Vesicle Fusion, 2017; Front Mol Neurosci. 10() 72. PMID:

Kiessling V., Liang B., Tamm L. K., Reconstituting SNARE-mediated membrane fusion at the single liposome level, 2017; Methods Cell Biol. 128() 339-63. PMID:

Yang S. T., Kiessling V., Tamm L. K., Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion, 2016; Nat Commun. 7() 11401. PMID:

Kreutzberger AJ, Liang B, Kiessling V, Tamm LK, Assembly and Comparison of Plasma Membrane SNARE Acceptor Complexes., 2016; Biophysical journal. 110(10) 2147-50. PMID: 27178662 | PMCID: PMC4881159

Yang ST, Kreutzberger AJB, Lee J, Kiessling V, Tamm LK, The role of cholesterol in membrane fusion., 2016; Chemistry and physics of lipids. 199() 136-143. PMID: 27179407 | PMCID: PMC4972649

Yang ST, Lim SI, Kiessling V, Kwon I, Tamm LK, Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein., 2016; Scientific reports. 6() 32866. PMID: 27605302 | PMCID: PMC5015116

Kiessling V., Yang S. T., Tamm L. K., Supported lipid bilayers as models for studying membrane domains, 2015; Curr Top Membr. 75() 1-23. PMID:

Yang S. T., Kiessling V., Simmons J. A., White J. M., Tamm L. K., HIV gp41-mediated membrane fusion occurs at edges of cholesterol-rich lipid domains, 2015; Nat Chem Biol. 11(6) 424-31. PMID:

Hernandez J. M., Kreutzberger A. J., Kiessling V., Tamm L. K., Jahn R., Variable cooperativity in SNARE-mediated membrane fusion, 2014; Proc Natl Acad Sci U S A. 111(33) 12037-42. PMID:

Liang B., Kiessling V., Tamm L. K., Prefusion structure of syntaxin-1A suggests pathway for folding into neuronal trans-SNARE complex fusion intermediate, 2013; Proc Natl Acad Sci U S A. 110(48) 19384-9. PMID:

Kiessling V., Ahmed S., Domanska M. K., Holt M. G., Jahn R., Tamm L. K., Rapid fusion of synaptic vesicles with reconstituted target SNARE membranes, 2013; Biophys J. 104(9) 1950-8. PMID:

Kiessling V., Wan C., Tamm L. K., Domain coupling in asymmetric lipid bilayers, 2008; Biochim Biophys Acta. 1788(1) 64-71. PMID:

Kiessling V., Crane J. M., Tamm L. K., Transbilayer effects of raft-like lipid domains in asymmetric planar bilayers measured by single molecule tracking, 2006; Biophys J. 91(9) 3313-26. PMID:

Kiessling V., Transbilayer coupling of lipid dynamics, ; Biophys J. 103(12) 2409-10. PMID:

Kreutzberger A. J., Kiessling V., Tamm L. K., High cholesterol obviates a prolonged hemifusion intermediate in fast SNARE-mediated membrane fusion, ; Biophys J. 109(2) 319-29. PMID:

Tamm L. K., Crane J., Kiessling V., Membrane fusion: a structural perspective on the interplay of lipids and proteins, ; Curr Opin Struct Biol. 13(4) 453-66. PMID:

Crane J. M., Kiessling V., Tamm L. K., Measuring lipid asymmetry in planar supported bilayers by fluorescence interference contrast microscopy, ; Langmuir. 21(4) 1377-88. PMID:

Domanska M. K., Kiessling V., Stein A., Fasshauer D., Tamm L. K., Single vesicle millisecond fusion kinetics reveals number of SNARE complexes optimal for fast SNARE-mediated membrane fusion, ; J Biol Chem. 284(46) 32158-66. PMID:

Domanska M. K., Kiessling V., Tamm L. K., Docking and fast fusion of synaptobrevin vesicles depends on the lipid compositions of the vesicle and the acceptor SNARE complex-containing target membrane, ; Biophys J. 99(9) 2936-46. PMID:

Kiessling V., Domanska M. K., Tamm L. K., Single SNARE-mediated vesicle fusion observed in vitro by polarized TIRFM, ; Biophys J. 99(12) 4047-55. PMID:

Kiessling V., Tamm L. K., Measuring distances in supported bilayers by fluorescence interference-contrast microscopy: polymer supports and SNARE proteins, ; Biophys J. 84(1) 408-18. PMID:

Kiessling V., Vassanelli S., Potassium channel gating in adhesion: from an oocyte-silicon to a neuron-astrocyte adhesion contact, ; Eur Biophys J. 34(2) 113-26. PMID:

Lu B., Kiessling V., Tamm L. K., Cafiso D. S., The juxtamembrane linker of full-length synaptotagmin 1 controls oligomerization and calcium-dependent membrane binding, ; J Biol Chem. 289(32) 22161-71. PMID:

Kreutzberger A. J., Liang B., Kiessling V., Tamm L. K., Assembly and Comparison of Plasma Membrane SNARE Acceptor Complexes, ; Biophys J. 110(10) 2147-50. PMID:

Kreutzberger A. J. B., Kiessling V., Liang B., Yang S. T., Castle J. D., Tamm L. K., Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability, ; Biophys J. 113(9) 1912-1915. PMID:

Moissoglu K., Kiessling V., Wan C., Hoffman B. D., Norambuena A., Tamm L. K., Schwartz M. A., Regulation of Rac1 translocation and activation by membrane domains and their boundaries, ; J Cell Sci. 127(0) 2565-76. PMID:

Murray D. H., Tamm L. K., Kiessling V., Supported double membranes, ; J Struct Biol. 168(1) 183-9. PMID:

Sanganna Gari R. R., Seelheim P., Marsh B., Kiessling V., Creutz C. E., Tamm L. K., Quaternary structure of the small amino acid transporter OprG from Pseudomonas aeruginosa, ; J Biol Chem. 293(44) 17267-17277. PMID:

Wan C., Kiessling V., Cafiso D. S., Tamm L. K., Partitioning of synaptotagmin I C2 domains between liquid-ordered and liquid-disordered inner leaflet lipid phases, ; Biochemistry. 50(13) 2478-85. PMID:

Wan C., Kiessling V., Tamm L. K., Coupling of cholesterol-rich lipid phases in asymmetric bilayers, ; Biochemistry. 47(7) 2190-8. PMID:

Yang S. T., Lim S. I., Kiessling V., Kwon I., Tamm L. K., Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein, ; Sci Rep. 6() 32866. PMID:

Zdanowicz R., Kreutzberger A., Liang B., Kiessling V., Tamm L. K., Cafiso D. S., Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion, ; Biophys J. 113(6) 1235-1250. PMID:

Kiessling V., Imaging fast SNARE mediated-membrane fusion in planar-supported bilayers, ; Biophys J. 89(4) 2185-6. PMID: