6/17/2025
Overview. We use diverse approaches - molecular virology, RNA biology, high throughput sequencing & bioinformatics - to understand how herpesviruses reshape the RNA landscape to influence infection outcomes.Why we study herpesviruses. Our…
6/17/2025
Our research is focused on the structure and function of macromolecular assemblies, using the techniques of electron cryo-microscopy and three-dimensional reconstruction. Historically, we have been working in two different areas:…
6/17/2025
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika COVID-19, Influenza, Zika fever, and Ebola hemorrhagic fever are diseases caused by highly pathogenic RNA viruses that…
6/17/2025
OVERVIEW: How does the body recognize an infectious organism? During infection, how does it determine when to escalate inflammation for pathogen clearance versus dampen inflammation to prevent damage to self? What…
6/17/2025
Our research focuses on the application of chemical engineering principles to problems in microbial ecology. The aim is to develop a fundamental understanding of mechanisms underlying microbial behavior which will…
6/17/2025
We develop nanoscale imaging methods for 3D single-molecule localization in intact bacterial cells. Our two primary research objectives are: 1. Development of 3D super-resolution imaging methods, including instrument design, sample preparation,…
6/17/2025
Multiple Sclerosis is a currently incurable autoimmune disease that affects 400,000 Americans and millions worldwide. The disease is characterized by destruction of myelin, the protective coat that wraps neuronal axons…
6/17/2025
Research in the Güler Malaria Lab focuses on the human-infective malaria parasite, Plasmodium falciparum. Some of our projects are described below: ·We are interested in underlying mechanisms that drive genetic change…
6/17/2025
My research is focused on elucidating the immunoregulatory mechanism by Hepatitis C virus (HCV). HCV is a global health concern causing severe liver disease such as fibrosis, cirrhosis and hepatocellular…
6/17/2025
Toxoplasma gondii is an intracellular, protozoan parasite that infects approximately one-third of the world population. The parasite can be acquired congenitally or in adults, through the ingestion of contaminated food…
