{"id":1730516,"date":"2025-06-17T11:13:10","date_gmt":"2025-06-17T15:13:10","guid":{"rendered":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/"},"modified":"2025-08-21T06:21:21","modified_gmt":"2025-08-21T10:21:21","slug":"ubc3yv","status":"publish","type":"faculty-listing","link":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/","title":{"rendered":"Chun, Changzoon"},"content":{"rendered":"

Cilia are evolutionary conserved subcellular organelles essential for various cellular functions including homeostasis, sensing external stimuli and mechanosensation. Dysfunctional cilia are implicated in a number of chronic disabling conditions in humans, collectively known as ciliopathies. The transition zone (TZ), a multiprotein complex at the base of the cilium, maintains the cilium\u2019s unique composition by regulating the entry and exit of proteins. The composition and organization of the TZ can vary among cilia in different organisms and cell types. We use Expansion microscopy (ExM) combined with super-resolution microscope to delineate the TZ structure in multiciliated chemosensory cilia in olfactory sensory neuron and a single mechanosensory primary cilium in vascular endothelium. Currently, our research focuses on investigating the mechanotransduction of endothelial primary cilia in the thoracic and abdominal aorta.<\/p>\n","protected":false},"featured_media":1735360,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_links_to":"","_links_to_target":""},"otheraff":[],"phd-degree":[],"primary":[2342],"research-discipline":[2512,2490,2500],"research-opportunity":[],"training-grant":[],"class_list":["post-1730516","faculty-listing","type-faculty-listing","status-publish","has-post-thumbnail","hentry","primary-pharmacology","research-discipline-cardiovascular-biology","research-discipline-molecular-biology","research-discipline-molecular-pharmacology"],"acf":[],"yoast_head":"\nChun, Changzoon - Research Faculty Directory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chun, Changzoon - Research Faculty Directory\" \/>\n<meta property=\"og:description\" content=\"Cilia are evolutionary conserved subcellular organelles essential for various cellular functions including homeostasis, sensing external stimuli and mechanosensation. Dysfunctional cilia are implicated in a number of chronic disabling conditions in humans, collectively known as ciliopathies. The transition zone (TZ), a multiprotein complex at the base of the cilium, maintains the cilium\u2019s unique composition by regulating […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/\" \/>\n<meta property=\"og:site_name\" content=\"Research Faculty Directory\" \/>\n<meta property=\"article:modified_time\" content=\"2025-08-21T10:21:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/08\/ubc3yv.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/\",\"url\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/\",\"name\":\"Chun, Changzoon - Research Faculty Directory\",\"isPartOf\":{\"@id\":\"https:\/\/med.virginia.edu\/faculty\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/08\/ubc3yv.jpeg\",\"datePublished\":\"2025-06-17T15:13:10+00:00\",\"dateModified\":\"2025-08-21T10:21:21+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/#primaryimage\",\"url\":\"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/08\/ubc3yv.jpeg\",\"contentUrl\":\"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/08\/ubc3yv.jpeg\",\"width\":600,\"height\":800,\"caption\":\"Changzoon Chun\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/med.virginia.edu\/faculty\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Chun, Changzoon\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/med.virginia.edu\/faculty\/#website\",\"url\":\"https:\/\/med.virginia.edu\/faculty\/\",\"name\":\"Research Faculty Directory\",\"description\":\"University of Virginia School of Medicine\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/med.virginia.edu\/faculty\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Chun, Changzoon - Research Faculty Directory","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/ubc3yv\/","og_locale":"en_US","og_type":"article","og_title":"Chun, Changzoon - Research Faculty Directory","og_description":"Cilia are evolutionary conserved subcellular organelles essential for various cellular functions including homeostasis, sensing external stimuli and mechanosensation. 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