{"id":1734063,"date":"2025-06-21T20:40:30","date_gmt":"2025-06-22T00:40:30","guid":{"rendered":"https:\/\/med.virginia.edu\/faculty\/?post_type=faculty-listing&#038;p=1734063"},"modified":"2025-06-27T06:41:04","modified_gmt":"2025-06-27T10:41:04","slug":"avs5u","status":"publish","type":"faculty-listing","link":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/","title":{"rendered":"Somlyo, Avril V."},"content":{"rendered":"<p>Our research focuses on the molecular basis of smooth muscle contraction, the role of RhoA GTP exchange factors (GEFs) and GTP activating proteins (GAPs) in smooth muscle signaling, and identifying selective therapeutic targets related to these molecules. Studies are conducted at various levels, from molecular to animal models, to understand the function of these signaling molecules in both normal and diseased states.<\/p>\n","protected":false},"featured_media":1734904,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_links_to":"","_links_to_target":""},"otheraff":[2392,2419],"phd-degree":[2572],"primary":[2335],"research-discipline":[2493,2494,2512,2509],"research-opportunity":[2546,2563,2560],"training-grant":[2320],"class_list":["post-1734063","faculty-listing","type-faculty-listing","status-publish","has-post-thumbnail","hentry","otheraff-cardiovascular-research-center","otheraff-chemical-and-structural-biology-program","phd-degree-phd-physiology","primary-molecular-physiology-and-biological-physics","research-discipline-biophysics","research-discipline-biophysics-structural-biology","research-discipline-cardiovascular-biology","research-discipline-physiology","research-opportunity-ro-biophysicsandstructuralbiology","research-opportunity-ro-cardiovasculardisease","research-opportunity-ro-physiologicalbasisofhumandisease","training-grant-basic-cardiovascular-research-training-grant"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Somlyo, Avril V. - Research Faculty Directory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Somlyo, Avril V. - Research Faculty Directory\" \/>\n<meta property=\"og:description\" content=\"Our research focuses on the molecular basis of smooth muscle contraction, the role of RhoA GTP exchange factors (GEFs) and GTP activating proteins (GAPs) in smooth muscle signaling, and identifying selective therapeutic targets related to these molecules. Studies are conducted at various levels, from molecular to animal models, to understand the function of these signaling [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/\" \/>\n<meta property=\"og:site_name\" content=\"Research Faculty Directory\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-27T10:41:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/06\/avs5u.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"100\" \/>\n\t<meta property=\"og:image:height\" content=\"133\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/\",\"url\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/\",\"name\":\"Somlyo, Avril V. - Research Faculty Directory\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/wp-content\\\/uploads\\\/sites\\\/45\\\/2025\\\/06\\\/avs5u.jpeg\",\"datePublished\":\"2025-06-22T00:40:30+00:00\",\"dateModified\":\"2025-06-27T10:41:04+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/#primaryimage\",\"url\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/wp-content\\\/uploads\\\/sites\\\/45\\\/2025\\\/06\\\/avs5u.jpeg\",\"contentUrl\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/wp-content\\\/uploads\\\/sites\\\/45\\\/2025\\\/06\\\/avs5u.jpeg\",\"width\":100,\"height\":133,\"caption\":\"Avril V. Somlyo\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/faculty-listing\\\/avs5u\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Somlyo, Avril V.\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/#website\",\"url\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/\",\"name\":\"Research Faculty Directory\",\"description\":\"University of Virginia School of Medicine\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/med.virginia.edu\\\/faculty\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Somlyo, Avril V. - Research Faculty Directory","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/","og_locale":"en_US","og_type":"article","og_title":"Somlyo, Avril V. - Research Faculty Directory","og_description":"Our research focuses on the molecular basis of smooth muscle contraction, the role of RhoA GTP exchange factors (GEFs) and GTP activating proteins (GAPs) in smooth muscle signaling, and identifying selective therapeutic targets related to these molecules. Studies are conducted at various levels, from molecular to animal models, to understand the function of these signaling [&hellip;]","og_url":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/","og_site_name":"Research Faculty Directory","article_modified_time":"2025-06-27T10:41:04+00:00","og_image":[{"width":100,"height":133,"url":"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/06\/avs5u.jpeg","type":"image\/jpeg"}],"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/","url":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/","name":"Somlyo, Avril V. - Research Faculty Directory","isPartOf":{"@id":"https:\/\/med.virginia.edu\/faculty\/#website"},"primaryImageOfPage":{"@id":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/#primaryimage"},"image":{"@id":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/#primaryimage"},"thumbnailUrl":"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/06\/avs5u.jpeg","datePublished":"2025-06-22T00:40:30+00:00","dateModified":"2025-06-27T10:41:04+00:00","breadcrumb":{"@id":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/#primaryimage","url":"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/06\/avs5u.jpeg","contentUrl":"https:\/\/med.virginia.edu\/faculty\/wp-content\/uploads\/sites\/45\/2025\/06\/avs5u.jpeg","width":100,"height":133,"caption":"Avril V. Somlyo"},{"@type":"BreadcrumbList","@id":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/avs5u\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/med.virginia.edu\/faculty\/"},{"@type":"ListItem","position":2,"name":"Somlyo, Avril V."}]},{"@type":"WebSite","@id":"https:\/\/med.virginia.edu\/faculty\/#website","url":"https:\/\/med.virginia.edu\/faculty\/","name":"Research Faculty Directory","description":"University of Virginia School of Medicine","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/med.virginia.edu\/faculty\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/faculty-listing\/1734063","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/faculty-listing"}],"about":[{"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/types\/faculty-listing"}],"version-history":[{"count":1,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/faculty-listing\/1734063\/revisions"}],"predecessor-version":[{"id":1734072,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/faculty-listing\/1734063\/revisions\/1734072"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/media\/1734904"}],"wp:attachment":[{"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/media?parent=1734063"}],"wp:term":[{"taxonomy":"otheraff","embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/otheraff?post=1734063"},{"taxonomy":"phd-degree","embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/phd-degree?post=1734063"},{"taxonomy":"primary","embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/primary?post=1734063"},{"taxonomy":"research-discipline","embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/research-discipline?post=1734063"},{"taxonomy":"research-opportunity","embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/research-opportunity?post=1734063"},{"taxonomy":"training-grant","embeddable":true,"href":"https:\/\/med.virginia.edu\/faculty\/wp-json\/wp\/v2\/training-grant?post=1734063"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}