{"id":1735491,"date":"2025-09-10T15:25:13","date_gmt":"2025-09-10T19:25:13","guid":{"rendered":"https:\/\/med.virginia.edu\/faculty\/?post_type=faculty-listing&#038;p=1735491"},"modified":"2025-09-17T06:36:06","modified_gmt":"2025-09-17T10:36:06","slug":"krl6c","status":"publish","type":"faculty-listing","link":"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/krl6c\/","title":{"rendered":"Levental, Kandice"},"content":{"rendered":"<p>The structure and composition of the plasma membrane is a major determinant of its function, and while recent advances in super-resolution microscopy and isolated mammalian plasma membranes have provided key insights into this relationship, major open questions remain.  For example, the precise molecular mechanisms of functional regulation of signaling by membrane domains are unknown.  Further, the diversity of plasma membrane structure and composition, and the impact of this diversity on those cells\u2019 functions, in various cell lineages have not been widely explored.  Finally, the majority of cellular lipids are derived directly from dietary sources, but how a cell is able to buffer dietary changes and maintain homeostasis is unclear. &#013;&#010;&#013;&#010;Combining tools from molecular and cell biology, membrane biophysics, protein biochemistry, and synthetic biology we seek to answer fundamental questions about the nature and function of cellular lipid membranes.&#013;&#010;<\/p>\n","protected":false},"featured_media":1735521,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_links_to":"","_links_to_target":""},"otheraff":[2396],"phd-degree":[],"primary":[2335],"research-discipline":[2516],"research-opportunity":[2546,2549,2559,2560],"training-grant":[],"class_list":["post-1735491","faculty-listing","type-faculty-listing","status-publish","has-post-thumbnail","hentry","otheraff-molecular-physiology-and-biological-physics","primary-molecular-physiology-and-biological-physics","research-discipline-molecular-physiology-and-biological-physics","research-opportunity-ro-biophysicsandstructuralbiology","research-opportunity-ro-cellbiology","research-opportunity-ro-chemistryandphysicsoflivingsystems","research-opportunity-ro-physiologicalbasisofhumandisease"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Levental, Kandice - Research Faculty Directory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/faculty\/faculty-listing\/krl6c\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Levental, Kandice - Research Faculty Directory\" \/>\n<meta property=\"og:description\" content=\"The structure and composition of the plasma membrane is a major determinant of its function, and while recent advances in super-resolution microscopy and isolated mammalian plasma membranes have provided key insights into this relationship, major open questions remain. For example, the precise molecular mechanisms of functional regulation of signaling by membrane domains are unknown. 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