Gene Targeted Mouse

The core outsources the gene targeting projects.  Once appropriately targeting ES cell clones have been identified, they should be expanded and aliquots refrozen, tested by karyotyping and for mycoplasma, and the core will schedule blastocyst injections with the desired number of clones in consultation with the investigator.
implanting/ changing a mouses dna to effect its genes before birth

homologous Recombination gene targeting timeline

micro organisms
mice huddling