{"id":5063,"date":"2023-02-01T16:33:43","date_gmt":"2023-02-01T21:33:43","guid":{"rendered":"https:\/\/med.virginia.edu\/cphg\/?p=5063"},"modified":"2026-05-22T16:24:25","modified_gmt":"2026-05-22T20:24:25","slug":"mete-civelek-phd-and-collaborators-identify-genes-that-play-key-roles-in-coronary-artery-disease","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/genome-sciences\/2023\/02\/01\/mete-civelek-phd-and-collaborators-identify-genes-that-play-key-roles-in-coronary-artery-disease\/","title":{"rendered":"Mete Civelek, PhD and Collaborators Identify Genes That Play Key Roles in Coronary Artery Disease"},"content":{"rendered":"

University of Virginia researchers and their collaborators have identified genes that play key roles in the development of\u00a0coronary artery disease<\/strong>, the No. 1 cause of death worldwide.<\/p>\n

UVA\u2019s findings essentially pick culprits responsible for coronary artery disease (CAD) out of a far, far larger lineup of potential genetic suspects. That gives scientists promising targets as they work to develop new and better treatments.<\/p>\n

\u201cGenetic studies done in more than 1 million people in the last 15 years identified hundreds of locations on our chromosomes that increase the risk of having a heart attack,\u201d said senior researcher Mete Civelek, PhD, of UVA\u2019s Center for Public Health Genomics and the Department of Biomedical Engineering<\/strong>, a joint program of the School of Medicine and School of Engineering. \u201cWe now identified the genes that are responsible for this risk at these locations. We will be able to use these findings as new therapeutic targets.\u201d<\/p>\n

Read complete story in\u00a0UVA Health Newsroom.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

University of Virginia researchers and their collaborators have identified genes that play key roles in the development of\u00a0coronary artery disease, the No. 1 cause of death worldwide. UVA\u2019s findings essentially pick culprits responsible for coronary artery disease (CAD) out of a far, far larger lineup of potential genetic suspects. That gives scientists promising targets as […]<\/p>\n","protected":false},"author":1287,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[3,8],"tags":[15,196,132],"class_list":["post-5063","post","type-post","status-publish","format-standard","hentry","category-homepage-feed","category-people","tag-cphg","tag-intranet","tag-mete-civelek"],"acf":false,"yoast_head":"\nMete Civelek, PhD and Collaborators Identify Genes That Play Key Roles in Coronary Artery Disease - Department of Genome Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/genome-sciences\/2023\/02\/01\/mete-civelek-phd-and-collaborators-identify-genes-that-play-key-roles-in-coronary-artery-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mete Civelek, PhD and Collaborators Identify Genes That Play Key Roles in Coronary Artery Disease - Department of Genome Sciences\" \/>\n<meta property=\"og:description\" content=\"University of Virginia researchers and their collaborators have identified genes that play key roles in the development of\u00a0coronary artery disease, the No. 1 cause of death worldwide. 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