{"id":512,"date":"2017-06-15T10:01:47","date_gmt":"2017-06-15T14:01:47","guid":{"rendered":"https:\/\/med.virginia.edu\/houpt-group\/?page_id=512"},"modified":"2018-03-29T15:12:39","modified_gmt":"2018-03-29T19:12:39","slug":"tac-collaborations","status":"publish","type":"page","link":"https:\/\/med.virginia.edu\/houpt-group\/research\/tac-collaborations\/","title":{"rendered":"TAC Collaborations"},"content":{"rendered":"

General Informational Guide to TaqMan Array Card Collaborations<\/strong><\/h1>\n

The TaqMan Array Card (TAC) is a 384-well customizable real-time PCR format (from Life Technologies\/Thermo Fisher) that can simultaneously detect 48 multiple infectious disease targets on 8 specimens. The technology compartmentalizes many assays such that (once developed) it is as easy to perform as a single real-time PCR reaction.\u00a0 We find that this makes TAC well-suited for field use, syndromic surveillance, and clinical research.\u00a0 We have developed custom-made cards for enteropathogens\/diarrheal diseases, for pathogens associated with acute febrile illness (with collaborators at CDC), for Mycobacterium tuberculosis<\/em> drug resistance mutations, for Streptococcus pneumoniae<\/em> serotyping, Malaria drug resistance, and others which we have used these extensively around the world.<\/p>\n

We are committed to sharing this useful technology widely for research purposes.\u00a0 However, running TaqMan Array Cards is also a considerable undertaking.\u00a0 Please review some of our layouts and publications below, and if you are interested further contact us<\/a> by email.\u00a0 Good luck!<\/p>\n

Enteric TAC
\n\"Enteric<\/strong>Reference:
\nLiu et al<\/em>., A Laboratory-Developed TaqMan Array Card for Simultaneous Detection of 19 Enteropathogens. J Clin Microbiol<\/em>. Feb 2013; 51(2):472-80<\/a><\/p>\n

 <\/p>\n

Tuberculosis Drug Resistance
\n\"Tuberculosis<\/strong>Reference:
\nPholwat et al<\/em>., Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis to Detect Tuberculosis Drug Resistance Mutations across 10 Genes. MBio<\/em>. Feb 2015; 6(2):e02273<\/a><\/p>\n

 <\/p>\n

Acute Febrile Illnesses
\n\"Acute<\/strong>Reference:
\nLiu et al<\/em>. Development of a TaqMan Array Card for Acute-Febrile-Illness Outbreak Investigation and Surveillance of Emerging Pathogens, including Ebola Virus. J Clin Microbiol<\/em>. Jan 2016; 54(1):49-58<\/a><\/p>\n

 <\/p>\n

Streptococcus pneumonieae
\n\"Streptococcus<\/em><\/strong>Reference:
\nPholwat et al<\/em>., Development of a TaqMan Array Card for Pneumococcal Serotyping on Isolates and Nasopharyngeal Samples. J Clin Microbiol<\/em>. Jul 2016; 54(7):1842-50<\/a><\/p>\n

 <\/p>\n

Malaria
\n\"Malaria<\/strong>Reference:
\nPholwat et al<\/em>. The Malaria TaqMan Array Card Includes 87 Assays for Plasmodium falciparum<\/em> Drug Resistance, Identification of Species, and Genotyping in a Single Reaction. Antimicrobial Agents Chemother<\/em>. Apr 2017; 61(5): pii:e00110-17<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

General Informational Guide to TaqMan Array Card Collaborations The TaqMan Array Card (TAC) is a 384-well customizable real-time PCR format (from Life Technologies\/Thermo Fisher) that can simultaneously detect 48 multiple infectious disease targets on 8 specimens. The technology compartmentalizes many assays such that (once developed) it is as easy to perform as a single real-time […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":170,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-512","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nTAC Collaborations - Houpt Group<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/houpt-group\/research\/tac-collaborations\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TAC Collaborations - Houpt Group\" \/>\n<meta property=\"og:description\" content=\"General Informational Guide to TaqMan Array Card Collaborations The TaqMan Array Card (TAC) is a 384-well customizable real-time PCR format (from Life Technologies\/Thermo Fisher) that can simultaneously detect 48 multiple infectious disease targets on 8 specimens. 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