Exocytosis and Secretion of Neurotransmitters and Hormones

Many hormones, neurotransmitters, and secretory proteins are released from cells by exocytosis, which involves complex vesicle trafficking and membrane fusion steps. Investigators at UVa are studying exocytosis and membrane fusion at the cellular and molecular level. Defects in neurotransmitter release lead to multiple neurological and neuro degenerative diseases including epilepsy, Parkinson’s, Alzheimer’s, schizophrenia, and mood disorders.

Faculty Members:

David Cafiso, David Castle, Carl Creutz, Christopher Stroupe, Lukas Tamm