{"id":6859,"date":"2024-05-30T15:04:24","date_gmt":"2024-05-30T15:04:24","guid":{"rendered":"https:\/\/med.virginia.edu\/mic\/?p=6859"},"modified":"2024-05-30T15:04:24","modified_gmt":"2024-05-30T15:04:24","slug":"anna-cliffe-phd-awarded-2-7-million-to-study-how-atrx-protein-protects-against-herpes-simplex-virus-which-impacts-more-than-60-of-the-u-s-population","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/mic\/2024\/05\/30\/anna-cliffe-phd-awarded-2-7-million-to-study-how-atrx-protein-protects-against-herpes-simplex-virus-which-impacts-more-than-60-of-the-u-s-population\/","title":{"rendered":"Anna Cliffe, PhD, Awarded $2.7 Million to Study How ATRX Protein Protects Against Herpes Simplex Virus, which impacts more than 60% of the U.S. population."},"content":{"rendered":"<p>Anna Cliffe, PhD, an associate professor in the Department of Microbiology, Immunology, and Cancer Biology, was awarded a $2.7 million R01 grant from the National Institutes of Health for a project titled \u201cThe role of ATRX in both promoting the establishment of HSV latency and restricting reactivation.\u201d<\/p>\n<p>The Cliffe lab studies mechanisms of Herpes Simplex Virus (HSV) latent infection and reactivation in neurons. More than 60% of the U.S. population is infected with the virus, which can cause a range of disease outcomes, including oral and genital lesions, keratitis, and encephalitis, and potentially contribute to the development of Alzheimer\u2019s disease. The virus persists for life as a latent infection of neurons and can periodically reactivate in response to a variety of stimuli to cause disease. \u00a0<a href=\"https:\/\/click.mc.virginia.edu\/?qs=304c74f86f79ab59e5f79f0b2e6350d85bacf26d5fb86042d4f84cc0ac8f517c6a7dce3238e8ad2c6d2c430f00e9361a350aa1692b47e3cf295d200dbb78114b\" data-linkto=\"https:\/\/\">LEARN MORE<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Anna Cliffe, PhD, an associate professor in the Department of Microbiology, Immunology, and Cancer Biology, was awarded a $2.7 million R01 grant from the National Institutes of Health for a project titled \u201cThe role of ATRX in both promoting the establishment of HSV latency and restricting reactivation.\u201d The Cliffe lab studies mechanisms of Herpes Simplex [&hellip;]<\/p>\n","protected":false},"author":181,"featured_media":6860,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[],"class_list":["post-6859","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news"],"acf":false,"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - 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