{"id":13,"date":"2015-07-04T22:41:07","date_gmt":"2015-07-05T02:41:07","guid":{"rendered":"http:\/\/cores.med.virginia.edutest-replo\/calendar\/"},"modified":"2024-11-13T11:48:37","modified_gmt":"2024-11-13T16:48:37","slug":"services","status":"publish","type":"page","link":"https:\/\/med.virginia.edu\/molecular-imaging-core\/services\/","title":{"rendered":"Services"},"content":{"rendered":"

The Molecular Imaging Center images small animals with MRI, CT, CT-SPECT, bioluminescence, fluorescence, MicroPET scans, some of which can be combined in multi-modality scans. The Center has image analysis software and produces custom imaging agents. The core offers training so investigators can perform their own experiments, or the core can perform the analyses. <\/span><\/p>\n

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Note that data from different modalities has been combined in many of the examples shown here.<\/p>\n

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Magnetic Resonance Imaging.<\/h4>\n
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  • Tumor imaging and sizing.<\/li>\n
  • Cardiac imaging<\/li>\n
  • 31<\/sup>P NMR non-localized spectroscopy<\/li>\n
  • Diffusion tensor imaging<\/li>\n
  • Fat water imaging<\/li>\n<\/ul>\n

    Data obtained at UVa<\/a><\/td>\n

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Bioluminescence \/ Fluorescence Imaging<\/h4>\n

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Positron Emission Tomography (PET)<\/h4>\n
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  • Fluorodeoxyglucose (18<\/sup>F-FDG) imaging of areas of hypermetabolic activity.<\/li>\n
  • Fluoride ion (18F-) bone imaging.<\/li>\n
  • Imaging of labeled targeted agents, e.g. 64<\/sup>Cu-f<\/i>MLP 18<\/sup>F labeled small molecules<\/li>\n
  • 18<\/sup>F fluorothymidine<\/li>\n
  • 13<\/sup>N ammonia<\/li>\n
  • Isotopes available from PETNET are 18<\/sup>F, 11<\/sup>C, 13<\/sup>N, 15<\/sup>O<\/li>\n<\/ul>\n<\/td>\n

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Ultrasound imaging<\/h4>\n
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  • visualization and sizing of tumor<\/li>\n
  • measuring blood flow in organs and tumors<\/li>\n
  • observing biomarkers of inflammation, tumor neovasculature, ischemia<\/li>\n
  • monitoring microbubble contrast agents<\/li>\n<\/ul>\n

    More applications and operational details on ultrasound<\/a> page.<\/td>\n

\"ultrasound<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

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Cyclotron<\/h4>\n

Production of short lived PET\u00a0isotopes\u00a011<\/sup>C, 13<\/sup>N, and 15<\/sup>O, gamma isotopes 67<\/sup>Ga, 123<\/sup>I, and 111<\/sup>In and 165<\/sup>Er, some of which are used in biomarkers synthesized on site.<\/p>\n

Chemistry Lab for Production of Custom Imaging Agents<\/h4>\n