Core faculty members and research scientists of the CIIR have available 13,000 square feet of recently renovated research space on the 4th and 5th floors of the University of Virginia Old Medical School building.<\/p>\n
The UVA Health System has a number of shared instrumentation facilities available to investigators and trainees interested in research:<\/p>\n
UVA Office of Research Core Administration<\/strong><\/a><\/p>\n Advanced Microscopy<\/strong><\/a> Beirne B. Carter Center for Immunology Research<\/strong><\/a> Biomolecular Analysis Facility (BAF)<\/strong><\/a> Biomolecular Magnetic Resonance Facility (BMRF)<\/strong><\/a> Biostatistics \u00bb Center for Biomedical Ethics<\/strong><\/a> Center for Cell Signaling<\/strong><\/a> Center for Comparative Medicine<\/strong><\/a> Flow Cytometry<\/strong><\/a> Genomic Analysis and Technology Core General Clinical Research Center (GCRC) \u00bb W.M. Keck Center for Cellular Imaging<\/strong><\/a> Molecular Imaging Core<\/strong><\/a> Molmart Product Core<\/strong><\/a> Research Histology Core<\/strong><\/a> Tissue Culture Facility<\/strong><\/a>
\nThis facility provides access to electron and light microscopes, training in microscope use and sample preparation, a full range of TEM and SEM preparatory services, and consultation regarding microscopy applications in biomedical investigations.<\/p>\n
\nThis center offers an outstanding Interdisciplinary Training Program in Immunology developed by internationally recognized faculty. Immunology research and training is focused in the areas of: allergy\/atopic disease, antigen presentation, autoimmunity, host immune response to infection, innate immune mechanisms, lymphocyte development, and tumor immunology.<\/p>\n
\nThe Biomolecular Analysis Facility (BAF) provides a centralized setting for a diverse but interactive suite of services, instrumentation, and\u00a0e<\/span>xpertise in the areas of proteomics, metabolomics, small molecules, and molecular interactions. Some instrumentation is available open-access while other services are provided by the staff.<\/p>\n
\nThis facility facilitates and promotes research that utilizes NMR (nuclear magnetic resonance) spectroscopy to examine biologically important molecules, providing information on molecular structure and dynamics at atomic level resolution.<\/p>\n
\nThe Division of Biostatistics and Epidemiology in the Department of Public Health Sciences of the School of Medicine provides collaborative consulting in study design, conduct, analysis, and interpretation.<\/p>\n
\nThis center’s mission is to advance education, research, and service concerning moral values in health care. The program is devoted to helping those in the public sector who are charged with making decisions to respond to the challenges facing health care systems.<\/p>\n
\nThis multidisciplinary biomedical research center in the School of Medicine provides a vibrant atmosphere to study cellular and molecular mechanisms of signal transduction.<\/p>\n
\nThis center’s mission is to support biomedical research and teaching that utilizes laboratory animals. This is done in a manner that promotes the policies set by the Institutional Animal Care and Use Committee (IACUC) whose charge is to oversee compliance by UVA personnel with federal regulations and guidelines.<\/p>\n
\nThe flow cytometry core provides state-of-the-art instrumentation such as the DIVA FACSVantage SE TurboSortT. Also offers 4 way high speed cell sorting and complex analytical services and has three dual laser FACSCaliburT benchtop analyzers. Recent additions include a Cyan ADP nine color benchtop cytometer, an Imagestream100 imaging flow cytometer and a Luminex 100 bead based multiplex analyzer.<\/p>\n
\n<\/strong><\/a>The Genome Analysis and Technology Core provides\u00a0high throughput (Next Generation) sequencing services\u00a0for both novice and experienced users alike, by providing timely assistance in all facets of experimentation from project design\/execution to data analysis\/reporting.
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\nThis NIH-sponsored facility includes a ten-bed, inpatient and outpatient multidisciplinary human clinical investigative unit that can be used by any qualified investigator and has been used by faculty from almost every department within the University, encompassing over 250 research protocols. The center maintains an Informatics Core that provides clinical investigators with the latest computer tools to facilitate the analysis of data and subsequent publication process needed after the compilation of research data. The core laboratory performs multiple specific assays of research-oriented human samples and to perform high-volume, high-precision estimation of human hormones by radioimmunoassay and immunoradiometric and chemiluminescence assays. Assay results are electronically stored in CRC computers for subsequent analysis of biorhythms.<\/p>\n
\nThis center is a state-of-the-art optical imaging facility that provides continual development and implementation of novel optical imaging methods that interface expertise in biology, optics and electronic engineering. The center has imaging systems to image from a single molecule to the whole animal, with specialized processing software including FRET and FLIM.<\/p>\n
\nThis facility offers the latest advances in imaging\/spectroscopy strategies for imaging in vivo of live animals, and excised human and animal organs.<\/p>\n
\nMolMart supplies molecular biology reagents to UVA researchers.<\/p>\n
\nThis facility provides a range of capabilities directed at correlative studies in basic, preclinical and clinical investigations. Services include: tissue fixation and processing, tissue sectioning, histology section staining, cell preparation for immunocytology, immunohistology and immunocytology, and laser capture microdissection. This core is closely tied to several others including the Genome\u00a0Analysis\u00a0&\u00a0Technology Core, Protein Sciences Core, Tissue Procurement Facility, and Molecular Assessment and Preclinical Studies Core.<\/p>\n
\nThis core facility is a central source of tissue culture media, reagents, sterile hood space, cell banking, cell culture consultation and specialized tissue culture cell services. The facility provides services to the UVA research community including cell culture and storage services, transfections, baculovirus transfections, viral titering, mycoplasma testing, and training in tissue culture techniques.<\/p>\n