Jasmin Herz, Ph.D.
Is has been a long-standing question as to how restrictions to immune cell entry into the brain and spinal cord parenchyma are overcome. My research seeks to understand the role of the meninges (tissues that surround the brain and spinal cord) and work cooperatively with peripheral immune cells to maintain homeostasis and counteract threats during viral infection. I investigate immune responses initiated locally through lymphatic vessels, meningeal dendritic cell mobilization, and reactivation of infiltrating antiviral T cells. Utilizing a multitude of applications, such as intra-vital microscopy, CyTOF and more classical molecular and histological approaches, I aim to set the foundation for translational studies in the field of Neurovirology to execute protective antiviral immunity of the central nervous tissue.