Selected Publications

Selected Publications (out of over 75)

Derecki N.C., Cardani A.N., Yang C.H., Quinnies K.M., Crihfield A., Lynch K.R., and Kipnis J (2010) Regulation of learning and memory by meningeal immunity: A key role for IL-4. J Exp Med. May 10;207(5):1067-80.

Lu Z., Elliott M.R., Chen Y., Walsh J.T., Klibanov, A.I., Ravichandran K.S. and Kipnis J. (2011) Phagocytic activity of neuronal progenitors regulates adult neurogenesis. Nat Cell Biol. Jul 31;13(9):1076-83.

Derecki N.C., Cronk J.C., Lu Z., Xu E., Abbott S.B.G., Guyenet P.G. and Kipnis J. (2012) Wild type microglia arrest pathology in a mouse model of Rett syndrome. Nature. Mar 18;484(7392):105-9.

Walsh JT, Hendrix S, Boato F, Smirnov I, Zheng J, Lukens JR, Gadani SP, Hechler D, Gölz G, Rosenberger K, Kammertöns T, Vogt J, Vogelaar C, Siffrin V, Radjavi A, Fernandez-Castaneda A, Gaultier A, Gold R, Kanneganti TD, Nitsch R, Zipp Z, and Kipnis J. (2015) MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. J Clin Invest  Feb;125(2):699-714.

Gadani SP, Walsh JT, Smirnov I, Zheng J and Kipnis J. (2015) The glia-derived alarmin IL-33 orchestrates the post CNS injury immune response and promotes recovery. Neuron. Feb 18;85(4):703-9.

Cronk JC, Derecki NC, Ji E, Xu Y, Lampano A, Smirnov I, Baker W, Norris GT, Coddington N, Wolf Y, Klibanov AL, Harris TH, Jung S, Litvak V, and Kipnis J. (2015) Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. Immunity, 42, 679-691.

Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, Derecki NC, Castle D, Mandell JW, Lee KS, Harris TH, Kipnis J. (2015) Structural and functional features of central nervous system lymphatics. Nature, Jul 16;523(7560):337-41. doi: 10.1038/nature14432.

Filiano AJ, Xu Y, Tustison NJ, Marsh RL, Baker W, Smirnov I, Overall CC, Gadani SP, Turner SD, Weng Z, Peerzade SN, Chen H, Lee KS, Scott MM, Beenhakker MP, Litvak V, Kipnis J. (2016) Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. Nature. Jul 21;535(7612):425-9.

Gadani SP, Smirnov I, Smith AT, Overall CC and Kipnis J (2017) Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury. J Exp Med., Feb;214(2):285-296.

Cronk JC, Filiano AJ, Louveau A, Marin I, Marsh R, Ji E, Goldman DH, Smirnov I, Geraci N, Acton S, Overall CC, Kipnis J. (2018) Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia. J Exp Med. Jun 4;215(6):1627-1647

Norris GT, Smirnov I, Filiano AJ, Shadowen HM, Cody KR, Thompson JA, Harris TH, Gaultier A, Overall CC, Kipnis J. (2018) Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury. J Exp Med. Jul 2;215(7):1789-1801.

Da Mesquita S, Louveau A, Vaccari A, Smirnov I, Cornelison RC, Kingsmore KM, Contarino C, Onengut-Gumuscu S, Farber E, Raper D, Viar KE, Powell RD, Baker W, Dabhi N, Bai R, Cao R, Hu S, Rich SS, Munson JM, Lopes MB, Overall CC, Acton ST, Kipnis J. (2018) Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease. Nature. Aug;560(7717):185-191.

PubMed complete list of publications