Publications

NLR-Dependent Regulation of Inflammation in Multiple Sclerosis

Frontiers in Immunology
Marjan Gharagozloo, Katsiaryna V. Gris, Tara Mahvelati, Abdelaziz Amrani, John R. Lukens, and Denis Gris

 

Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.

Journal of Immunology
Jillian P. Rhoads, John R. Lukens, Ashley J. Wilhelm, Jared L. Moore, Yanice Mendez-Fernandez, Thirumala-Devi Kanneganti and Amy S. Major

 

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease

Immunity
Prajwal Gurung, Gaofeng Fan, John R. Lukens, Peter Vogel, Nicholas K. Tonks, Thirumala-Devi Kanneganti

 

 

 lukens1Emerging Roles for the Immune System in Traumatic Brain Injury

Frontiers in Immunology
Celia A. McKee, John R. Lukens

 

Untitled

The Brain’s Reward Circuitry Regulates Immunity.

Nature
Elizabeth L Frost, John R. Lukens

 

 

NEURON_87_1.c1.indd

Dealing with Danger in the CNS: The Response of the Immune System to Injury

Neuron
Sachin P. Gadani, James T. Walsh, John R. Lukens, Jonathan Kipnis

 

IMMUNI_42_4_C1.indd

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells.

Immunity
Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD.

Dietary Modulation

Dietary modulation of the microbiome affects autoinflammatory disease.

Nature
Lukens JR, Gurung P, Vogel P, Johnson GR, Carter RA, McGoldrick DJ, Bandi SR, Calabrese CR, Vande Walle L, Lamkanfi M, Kanneganti TD.

RIP1-Driven Autoinflammation

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

Nature Medicine
Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD.

 

Critical Role for Inflammasome

Critical role for inflammasome-independent IL-1β production in osteomyelitis.

Proceedings of the National Academy of Sciences USA
Lukens JR, Gross JM, Calabrese C, Iwakura Y, Lamkanfi M, Vogel P, Kanneganti TD.

 

Inflammasome-Derived IL-1B

Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells.

The Journal of Immunology
Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD.

 

Beyond Canonical Inflammasomes

Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease.

Seminars in Immunopathology
Lukens JR, Kanneganti TD.

 

IL-1 family cytokines trigger sterile inflammatory disease

IL-1 family cytokines trigger sterile inflammatory disease.

Frontiers in Immunology
Lukens JR, Gross JM, Kanneganti TD.

 

 

 

 

Complete PubMed publication list