Publications

Th17 Cells in Parkinson’s Disease: The Bane of the Midbrain.

Cell Stem Cell
Ashley C. Bolte, John R. Lukens.

 

 

Critical Roles for Microbiota-Mediated Regulation of the Immune System in a Prenatal Immune Activation Model of Autism.

Journal of Immunology
Catherine R. Lammert, Elizabeth L. Frost, Ashley C. Bolte, Matt J. Paysour, Mariah E. Shaw, Calli E. Bellinger, Thaddeus K. Weigel, Eli R. Zunder and John R. Lukens.

 

NLR-Dependent Regulation of Inflammation in Multiple Sclerosis.

Frontiers in Immunology
Marjan Gharagozloo, Katsiaryna V. Gris, Tara Mahvelati, Abdelaziz Amrani, John R. Lukens, and Denis Gris.

 

 

Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9.

Journal of Immunology
Jillian P. Rhoads, John R. Lukens, Ashley J. Wilhelm, Jared L. Moore, Yanice Mendez-Fernandez, Thirumala-Devi Kanneganti and Amy S. Major.

 

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.

Immunity
Prajwal Gurung, Gaofeng Fan, John R. Lukens, Peter Vogel, Nicholas K. Tonks, Thirumala-Devi Kanneganti.

 

 

 Emerging Roles for the Immune System in Traumatic Brain Injury.

Frontiers in Immunology
Celia A. McKee, John R. Lukens.

 

Untitled

The Brain’s Reward Circuitry Regulates Immunity.

Nature
Elizabeth L Frost, John R. Lukens.

 

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Dealing with Danger in the CNS: The Response of the Immune System to Injury.

Neuron
Sachin P. Gadani, James T. Walsh, John R. Lukens, Jonathan Kipnis.

 

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The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells.

Immunity
Lukens JR, Gurung P, Shaw PJ, Barr MJ, Zaki MH, Brown SA, Vogel P, Chi H, Kanneganti TD.

Dietary Modulation

Dietary modulation of the microbiome affects autoinflammatory disease.

Nature
Lukens JR, Gurung P, Vogel P, Johnson GR, Carter RA, McGoldrick DJ, Bandi SR, Calabrese CR, Vande Walle L, Lamkanfi M, Kanneganti TD.

RIP1-Driven Autoinflammation

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

Nature
Lukens JR, Vogel P, Johnson GR, Kelliher MA, Iwakura Y, Lamkanfi M, Kanneganti TD.

 

Critical Role for Inflammasome

Critical role for inflammasome-independent IL-1β production in osteomyelitis.

Proceedings of the National Academy of Sciences USA
Lukens JR, Gross JM, Calabrese C, Iwakura Y, Lamkanfi M, Vogel P, Kanneganti TD.

 

Inflammasome-Derived IL-1B

Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells.

The Journal of Immunology
Lukens JR, Barr MJ, Chaplin DD, Chi H, Kanneganti TD.

 

Beyond Canonical Inflammasomes

Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease.

Seminars in Immunopathology
Lukens JR, Kanneganti TD.

 

IL-1 family cytokines trigger sterile inflammatory disease

IL-1 family cytokines trigger sterile inflammatory disease.

Frontiers in Immunology
Lukens JR, Gross JM, Kanneganti TD.

 

 

 

 

Complete PubMed publication list