{"id":3909,"date":"2024-12-19T11:14:08","date_gmt":"2024-12-19T16:14:08","guid":{"rendered":"https:\/\/med.virginia.edu\/neuroscience\/?p=3909"},"modified":"2024-12-19T11:14:08","modified_gmt":"2024-12-19T16:14:08","slug":"lulu-jiang-awarded-3-6-million-to-investigate-rna-modifications-in-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/neuroscience\/2024\/12\/19\/lulu-jiang-awarded-3-6-million-to-investigate-rna-modifications-in-alzheimers-disease\/","title":{"rendered":"Lulu Jiang Awarded $3.6 Million to Investigate RNA Modifications in Alzheimer\u2019s Disease"},"content":{"rendered":"

December 2024 – Congrats to Lulu Jiang, who was awarded a $3.6 million R01 grant from the National Institute on Aging for her project titled \u201cEpitranscriptomic Mechanism in the Pathogenesis of Alzheimer\u2019s Disease.\u201d Dr. Jiang\u2019s project will investigate a novel aspect of AD biology: the role of RNA modifications in disease progression. Recent findings from her research show that tau aggregation is associated with increased levels of m6A-modified RNA, which disrupts protein translation and contributes to neuronal dysfunction. Her study aims to uncover how dysregulated RNA modifications drive AD pathogenesis and evaluate potential therapeutic strategies. If successful, this work could provide transformative insights into the molecular mechanisms underlying AD and inform the development of novel RNA-targeted therapies.<\/p>\n

Visit this link for the full announcement!<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

December 2024 – Congrats to Lulu Jiang, who was awarded a $3.6 million R01 grant from the National Institute on Aging for her project titled \u201cEpitranscriptomic Mechanism in the Pathogenesis of Alzheimer\u2019s Disease.\u201d Dr. Jiang\u2019s project will investigate a novel aspect of AD biology: the role of RNA modifications in disease progression. Recent findings from […]<\/p>\n","protected":false},"author":2002,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"class_list":["post-3909","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":false,"yoast_head":"\nLulu Jiang Awarded $3.6 Million to Investigate RNA Modifications in Alzheimer\u2019s Disease - Neuroscience<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/neuroscience\/2024\/12\/19\/lulu-jiang-awarded-3-6-million-to-investigate-rna-modifications-in-alzheimers-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lulu Jiang Awarded $3.6 Million to Investigate RNA Modifications in Alzheimer\u2019s Disease - Neuroscience\" \/>\n<meta property=\"og:description\" content=\"December 2024 – Congrats to Lulu Jiang, who was awarded a $3.6 million R01 grant from the National Institute on Aging for her project titled \u201cEpitranscriptomic Mechanism in the Pathogenesis of Alzheimer\u2019s Disease.\u201d Dr. Jiang\u2019s project will investigate a novel aspect of AD biology: the role of RNA modifications in disease progression. 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