Shyam Raghavan, M.D.

Syam Raghavan, M.D.
Assistant Professor of Pathology


Medical School: Stanford University School of Medicine, 2012
Residency:University of California San Francisco, Plastic and Reconstructive Surgery, 2012-2016
Stanford University School of Medicine, Anatomic Pathology, 2016-2019
Fellowships: Stanford University School of Medicine, Gastrointestinal Pathology, 2018-2019
Stanford University School of Medicine, Dermatopathology, 2019-2020


Dermatopathology; General surgical pathology with specialization in gastrointestinal pathology and soft tissue pathology


I have a particular interest in studying the molecular drivers of melanocytic neoplasia, but am also involved in the study of both soft tissue tumors as well as mesenchymal tumors of the gastrointestinal tract.


  1. Puing AG, Raghavan SS, Aleshin MA, Ho DY. Hemophagocytic lymphohistiocytosis secondary to progressive disseminated histoplasmosis presenting as cellulitis. Med Mycol Case Rep. 2021 Jun 24;33:18-20. doi: 10.1016/j.mmcr.2021.06.002.
  2. Gru AA, Bacchi CE, Pulitzer M, Bhagat G, Kempf W, Robson A, Plaza JA, Pincus L, Raghavan SS, Xu M, Vencato da Silva T, Salavaggione AL, Subtil A, Battistella M. Secondary skin involvement in classic Hodgkin lymphoma: Results of an international collaborative cutaneous lymphoma working group study of 25 patients. J Cutan Pathol. 2021 Jun 4. doi: 10.1111/cup.14077.
  3. Craddock AP, Gru AA, Mannschreck D, Wilson BB, Raghavan SS. Primary Cutaneous Monomorphic Post-transplant Lymphoproliferative Disorder Mimicking Squamous Cell Carcinoma In Situ. Am J Dermatopathol. 2021 Apr 21. doi: 10.1097/DAD.0000000000001950.
  4. Hobbs LK, Noland MB, Raghavan SS, Gru AA. Pemphigus erythematosus: A case series from a tertiary academic center and literature review. J Cutan Pathol. 2021 Aug;48(8):1038-1050. doi: 10.1111/cup.13992.
  5. Czech MM, Nayak AK, Subramanian K, Suarez JF, Ferguson J, Jacobson KB, Montgomery SP, Chang M, Bae GH, Raghavan SS, Wang H, Miranti E, Budvytiene I, Shoor SM, Banaei N, Rieger K, Deresinski S, Holubar M, Blackburn BG. Reactivation of Chagas Disease in a Patient With an Autoimmune Rheumatic Disease: Case Report and Review of the Literature. Open Forum Infect Dis. 2021 Feb 5;8(2):ofaa642. doi: 10.1093/ofid/ofaa642.
  6. Gradecki SE, Gru AA, Rieger KE, Raghavan SS. Histopathology of primary cutaneous adenoid cystic carcinoma of the scrotum presenting with predominantly solid growth. J Cutan Pathol. 2020 Dec 14. doi: 10.1111/cup.13928.
  7. Hirotsu KE, Rana J, Wang JY, Raghavan SS, Rieger KE, Srinivas S, Fan AC, Kwong BY, Novoa RA, Zaba LC. Clinicopathologic characterization of enfortumab vedotin-associated cutaneous toxicity in patients with urothelial carcinoma. J Am Acad Dermatol. 2020 Dec 7:S0190-9622(20)33156-X. doi: 10.1016/j.jaad.2020.11.067.
  8. Gru AA, Bhagat G, Subtil A, Raghavan SS, Pulitzer M, Chung C, Sangueza M, Plaza JA. Spindle-cell (Sarcomatoid) Variant of Cutaneous Anaplastic Large-cell Lymphoma (C-ALCL): An Unusual Mimicker of Cutaneous Malignant Mesenchymal Tumors-A Series of 11 Cases. Am J Surg Pathol. 2021 Jun 1;45(6):796-802. doi: 10.1097/PAS.0000000000001623.
  9. Chang MS, Bae GH, Almazan T, Raghavan SS, Wang JY, Czech MM, Wang H, Banaei N, Blackburn BG, Novoa RA, Rieger KE. Concurrent Trypanosoma cruzi and Cytomegalovirus Reactivation in an Immunosuppressed Patient With Limited Cutaneous Systemic Sclerosis. Am J Dermatopathol. 2020 Nov 16. doi: 10.1097/DAD.0000000000001842.
  10. Brown RA, Wang JY, Raghavan SS, Zhang J, Wan DC, Born D, Koo M, Hazard FK, Novoa RA, Rieger KE. ALK-positive compound Spitz nevus with extensive perineural and intraneural neurotropism. J Cutan Pathol. 2021 Jan;48(1):154-159. doi: 10.1111/cup.13890.
  11. Raghavan SS, Kapler ES, Dinges MM, Bastian BC, Yeh I. Eruptive Spitz nevus, a striking example of benign metastasis. Sci Rep. 2020 Oct 1;10(1):16216. doi: 10.1038/s41598-020-73264-0.
  12. Wang JY, Hirotsu KE, Neal TM, Raghavan SS, Kwong BY, Khodadoust MS, Brown RA, Novoa RA, Kim YH, Rieger KE. Histopathologic Characterization of Mogamulizumab-associated Rash. Am J Surg Pathol. 2020 Dec;44(12):1666-1676. doi: 10.1097/PAS.0000000000001587.
  13. Scapa JV, Cloutier JM, Raghavan SS, Peters-Schulze G, Varma S, Charville GW. DDIT3 Immunohistochemistry Is a Useful Tool for the Diagnosis of Myxoid Liposarcoma. Am J Surg Pathol. 2021 Feb 1;45(2):230-239. doi: 10.1097/PAS.0000000000001564.
  14. Raghavan SS, Wang JY, Kwok S, Rieger KE, Novoa RA, Brown RA. PRAME expression in melanocytic proliferations with intermediate histopathologic or spitzoid features. J Cutan Pathol. 2020 Dec;47(12):1123-1131. doi: 10.1111/cup.13818.
  15. Raghavan SS, Wang JY, Toland A, Bangs CD, Rieger KE, Novoa RA, Charville GW, Brown RA. Diffuse PRAME expression is highly specific for malignant melanoma in the distinction from clear cell sarcoma. J Cutan Pathol. 2020 Dec;47(12):1226-1228. doi: 10.1111/cup.13812.
  16. Raghavan SS, Saleem A, Wang JY, Rieger KE, Brown RA, Novoa RA. Diagnostic Utility of LEF1 Immunohistochemistry in Differentiating Deep Penetrating Nevi From Histologic Mimics. Am J Surg Pathol. 2020 Oct;44(10):1413-1418. doi: 10.1097/PAS.0000000000001513.
  17. Raghavan SS, Clark M, Louie CY, Jensen KC, Dietrich B, Beadle BM, El-Sawy T, Baik F, Kunder CA, Brown RA. Molecular profiling of a primary cutaneous signet-ring cell/histiocytoid carcinoma of the eyelid. J Cutan Pathol. 2020 Sep;47(9):860-864. doi: 10.1111/cup.13733.