{"id":205,"date":"2015-11-13T13:46:48","date_gmt":"2015-11-13T18:46:48","guid":{"rendered":"https:\/\/med.virginia.edu\/pathology\/?page_id=205"},"modified":"2025-08-27T10:26:40","modified_gmt":"2025-08-27T14:26:40","slug":"m-beatriz-s-lopes-m-d-ph-d","status":"publish","type":"page","link":"https:\/\/med.virginia.edu\/pathology\/contact\/m-beatriz-s-lopes-m-d-ph-d\/","title":{"rendered":"M. Beatriz S. Lopes, M.D., Ph.D."},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-4845\" src=\"https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-211x300.jpg\" alt=\"\" width=\"211\" height=\"300\" srcset=\"https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-211x300.jpg 211w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-720x1024.jpg 720w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-105x150.jpg 105w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-768x1093.jpg 768w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-1080x1536.jpg 1080w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic-141x200.jpg 141w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2022\/04\/Lopes-Web-Pic.jpg 1192w\" sizes=\"(max-width: 211px) 100vw, 211px\" \/><\/p>\n<p>Professor Emeritus of Pathology<\/p>\n<h4><span class=\"wdcfontSize2\">EDUCATION<\/span><span class=\"wdcfontSize2\"><span class=\"wdcfontSize2\">:<\/span><\/span><\/h4>\n<p><b>Medical School<\/b>: University of Sao Paulo School of Medicine, December 1982, MD, January 1993, PhD)<br \/>\n<b>Residency:<\/b> Anatomic Pathology, University of Sao Paulo School of Medicine, January 1983 &#8211; January 1986<br \/>\n<b>Fellowship:<\/b> Neuropathology, University of Sao Paulo School of Medicine, February 1986 &#8211; December 1988; Fellowship in Neuropathology, University of Virginia \u00a0Health Sciences Center, January 1989 &#8211; December 1992<\/p>\n<h4>CLINICAL<span class=\"wdcfontSize2\">:<\/span><\/h4>\n<p><span class=\"wdcfontSize2\">Neuropathology, Pituitary Pathology, Autopsy Pathology.<\/span><\/p>\n<h4>RESEARCH INTERESTS<span class=\"wdcfontSize2\">:<\/span><\/h4>\n<p class=\"fontsize12\">My research interests focus on two major areas: 1- Hypothalamic, pituitary and peripheral interactions in the pathogenesis of pituitary adenomas; 2 \u2013 Molecular mechanisms of pathogenesis and invasion of brain tumors. Experimental techniques in our laboratory include cell culture, immunohistochemistry, immunofluorescence, and in situ hybridization.<\/p>\n<h4>REFERENCES<span class=\"wdcfontSize2\">:<\/span><\/h4>\n<ul class=\"noindent\">\n<li><strong>Lopes MB<\/strong>, Sloan E, Polder J. Mixed Gangliocytoma-Pituitary Adenoma: Insights on the Pathogenesis of a Rare Sellar Tumor. Am J Surg Pathol. 2017 May;41 (5):586-595. PubMed PMID: 28079576.<\/li>\n<li>Louis DN, Wesseling P, Paulus W, Giannini C, Batchelor TT, Cairncross JG, Capper D, Figarella-Branger D, <strong>Lopes MB<\/strong>, Wick W, van den Bent M. cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC). Acta 2018 Mar;135(3):481-484. PubMed PMID: 29372318.<\/li>\n<li>Louis DN, Giannini C, Capper D, Paulus W, Figarella-Branger D, <strong>Lopes MB<\/strong>, Batchelor TT, Cairncross JG, van den Bent M, Wick W, Wesseling P. cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma\/anaplastic astrocytoma, IDH-mutant. Acta Neuropathol. 2018 Apr;135(4):639-642. PubMed PMID: 29497819.<\/li>\n<li>Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, \u2026 <strong>Lopes B<\/strong>, \u2026 von Deimling A, Pfister SM. DNA methylation-based classification of central nervous system tumours. Nature. 2018 Mar 22;555(7697):469-474. PubMed PMID: 29539639.<\/li>\n<li><strong>Lopes MBS<\/strong>. Pathology of prolactinomas: any predictive value? Pituitary. 2020 Feb;23(1):3-8. doi: 10.1007\/s11102-019-00997-1. PMID: 31641970 Review.<\/li>\n<li><strong>Lopes MBS<\/strong>. World Health Organization 2017 Classification of Pituitary Tumors. Endocrinol Metab Clin North Am. 2020 Sep;49(3):375-386. doi: 10.1016\/j.ecl.2020.05.001. Epub 2020 Jul 15. PMID: 32741477.<\/li>\n<li>Patel SH, Batchala PP, Mrachek EKS, <strong>Lopes MBS<\/strong>, Schiff D, Fadul CE, Patrie JT, Jain R, Druzgal TJ, Williams ES. MRI and CT Identify Isocitrate Dehydrogenase (IDH)-Mutant Lower-Grade Gliomas Misclassified to 1p\/19q Codeletion Status with Fluorescence in Situ Hybridization. 2020 Jan;294(1):160-167. doi: 10.1148\/radiol.2019191140. Epub 2019 Nov 12. PMID: 31714193.<\/li>\n<\/ul>\n<h4>BOOK CHAPTERS<span class=\"wdcfontSize2\">:<\/span><\/h4>\n<div>\n<p>Kleinschmidt-DeMasters BK, <strong>Lopes MBS<\/strong>. Histologic Features of Pituitary Adenomas and Sellar Region Masses. In: Practical Surgical Neuropathology: a Diagnostic Approach. 2nd Ed. Perry A, Brat DJ (Eds.), Elsevier, 2018, pp 453-492<\/p>\n<p><strong>Lopes MBS<\/strong>. Pituitary and Sellar Region. In: Histology for Pathologists. 5th Ed. Mills SE (Ed.). Wolters Kluwer, 2020, pp 270-299.<\/p>\n<p><strong>Lopes MBS<\/strong>. Tumors of the Pituitary Gland. In: Diagnostic Histopathology of Tumors. 5th Ed. Fletcher CDM (ed.) Elsevier, 2020, pp. 1211-1243.<\/p>\n<p><strong>Lopes MBS<\/strong>, VandenBerg SR. Tumors of the Central Nervous System. In: Diagnostic Histopathology of Tumors. 5th Ed. Fletcher CDM (ed.) Elsevier, 2020, pp. 2067-2171.<\/p>\n<\/div>\n<p>A more complete list of Dr. Lopes&#8217; publications can be obtained from <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?orig_db=PubMed&amp;db=PubMed&amp;cmd=Search&amp;term=Lopes%2C%20Beatriz%20S%5Bauthor%5D\">PubMed.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Professor Emeritus of Pathology EDUCATION: Medical School: University of Sao Paulo School of Medicine, December 1982, MD, January 1993, PhD) Residency: Anatomic Pathology, University of Sao Paulo School of Medicine, January 1983 &#8211; January 1986 Fellowship: Neuropathology, University of Sao Paulo School of Medicine, February 1986 &#8211; December 1988; Fellowship in Neuropathology, University of Virginia [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":14,"menu_order":26,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-205","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>M. 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